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Wearable Sensors in Healthcare and Sensor-Enhanced Health Information Systems: All Our Tomorrows?
Michael Marschollek,Matthias Gietzelt,Mareike Schulze,Martin Kohlmann,Bianying Song,Klaus-Hendrik Wolf 대한의료정보학회 2012 Healthcare Informatics Research Vol.18 No.2
Wearable sensor systems which allow for remote or self-monitoring of health-related parameters are regarded as one means to alleviate the consequences of demographic change. This paper aims to summarize current research in wearable sensors as well as in sensor-enhanced health information systems. Wearable sensor technologies are already advanced in terms of their technical capabilities and are frequently used for cardio-vascular monitoring. Epidemiologic predictions suggest that neuropsychiatric diseases will have a growing impact on our health systems and thus should be addressed more intensively. Two current project examples demonstrate the benefit of wearable sensor technologies: long-term, objective measurement under daily-life, unsupervised conditions. Finally, up-to-date approaches for the implementation of sensor-enhanced health information systems are outlined. Wearable sensors are an integral part of future pervasive, ubiquitous and person-centered health care delivery. Future challenges include their integration into sensor-enhanced health information systems and sound evaluation studies involving measures of workload reduction and costs.
Taek Hun Kwon,Kyoungin Min,Matthias Wolf,Changill Ban,Tae Gyun Kim 한국구조생물학회 2022 Biodesign Vol.10 No.2
Ribose 5-phosphate isomerase is an enzyme that interconverts ribose 5-phosphate and ribulose 5-phosphate in the pentose phosphate pathway, which participates in NADPH generation, as well as an oxidative and non-oxidative synthesis of pentose sugars. Two distinct forms, ribose 5-phosphate isomerase A (RpiA) and ribose 5-phosphate isomerase B (RpiB), show no sequence identity even though they exist as ubiquitous, highly-conserved proteins in most kingdoms. RpiB from pathogenic, marine Vibrio vulnificus YJ016 (VvRpiB) was purified, crystallized, and analyzed to determine its structure in the apo form and in complex with a ligand. Crystals of the apo form of VvRpiB diffracted X-rays to 3.06 Å resolution, belonging to tetragonal space group I41 while co-crystals of VvRpiB with R5P belonged to the monoclinic space group C2 and diffracted X-rays to 2.07 Å resolution.
Jigeun Nam,Tawoo Kim,Jungkyu Park,Eunae Jo,Nadine Wolf,Thomas Strache,Julia Hahn,Schmidt Matthias,Christian Polak 한국정밀공학회 2024 International Journal of Precision Engineering and Vol.25 No.3
Amorphous metal is used in various applications due to high strength, elastic limit, and excellent soft magnetic properties, but fracture characteristics may deteriorate due to surface roughness or defects generated during manufacturing. So, in this study, we have investigated the effect of mechanical surface treatment on the fracture characteristics of amorphous metal foil. Unlike stainless steel sheets manufactured by the rolling process, amorphous metal foils have a rough surface and surface defects such as fine dimples and stripe patterns generated during the manufacturing process. After mechanical surface treatment such as brushing and grinding, surface roughness and mechanical properties of each specimen were compared. Through surface treatment, surface roughness was improved and defects such as dimple were removed. While the surface roughness Ra value of untreated sample was 0.6 on the wheel side and 0.4 on the air side, after surface treatment, the Ra value was lowered to less than 0.2 on both sides. Tensile tests were conducted to compare the mechanical characteristics of specimens. In case of the brushed or grinded samples, fracture strain increased from 1.5 to 1.8%, but no change in the elastic modulus was observed. Folding tests under repeated bending loads also showed that the durability of the surface treated sample was improved. This is considered to be an effect of eliminating surface defects that begin to crack.