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      • SCOPUSKCI등재

        Lymphedema Fat Graft: An Ideal Filler for Facial Rejuvenation

        Nicoli, Fabio,Chilgar, Ram M.,Sapountzis, Stamatis,Lazzeri, Davide,Yeo, Matthew Sze Wei,Ciudad, Pedro,Nicoli, Marzia,Lim, Seong Yoon,Chen, Pei-Yu,Constantinides, Joannis,Chen, Hung-Chi Korean Society of Plastic and Reconstructive Surge 2014 Archives of Plastic Surgery Vol.41 No.5

        Lymphedema is a chronic disorder characterized by lymph stasis in the subcutaneous tissue. Lymphatic fluid contains several components including hyaluronic acid and has many important properties. Over the past few years, significant research has been performed to identify an ideal tissue to implant as a filler. Because of its unique composition, fat harvested from the lymphedema tissue is an interesting topic for investigation and has significant potential for application as a filler, particularly in facial rejuvenation. Over a 36-month period, we treated and assessed 8 patients with lymphedematous limbs who concurrently underwent facial rejuvenation with lymphedema fat (LF). We conducted a pre- and postoperative satisfaction questionnaire survey and a histological assessment of the harvested LF fat. The overall mean general appearance score at an average of 6 months after the procedure was $7.2{\pm}0.5$, demonstrating great improvement. Patients reported significant improvement in their skin texture with a reading of $8.5{\pm}0.7$ and an improvement in their self-esteem. This study demonstrates that LF as an ideal autologous injectable filler is clinically applicable and easily available in patients with lymphedema. We recommend the further study and clinical use of this tissue as it exhibits important properties and qualities for future applications and research.

      • KCI등재

        Lymphedema Fat Graft: An Ideal Filler for Facial Rejuvenation

        Fabio Nicoli,Ram M. Chilgar,Stamatis Sapountzis,Davide Lazzeri,Matthew Yeo Sze Wei,Pedro Ciudad,Marzia Nicoli,Seong Yoon Lim,Pei-Yu Chen,Joannis Constantinides,Hung-Chi Chen 대한성형외과학회 2014 Archives of Plastic Surgery Vol.41 No.5

        Lymphedema is a chronic disorder characterized by lymph stasis in the subcutaneous tissue. Lymphatic fluid contains several components including hyaluronic acid and has manyimportant properties. Over the past few years, significant research has been performed toidentify an ideal tissue to implant as a filler. Because of its unique composition, fat harvestedfrom the lymphedema tissue is an interesting topic for investigation and has significantpotential for application as a filler, particularly in facial rejuvenation. Over a 36-monthperiod, we treated and assessed 8 patients with lymphedematous limbs who concurrentlyunderwent facial rejuvenation with lymphedema fat (LF). We conducted a pre- and postoperativesatisfaction questionnaire survey and a histological assessment of the harvested LFfat. The overall mean general appearance score at an average of 6 months after the procedurewas 7.2±0.5, demonstrating great improvement. Patients reported significant improvementin their skin texture with a reading of 8.5±0.7 and an improvement in their self-esteem. Thisstudy demonstrates that LF as an ideal autologous injectable filler is clinically applicable andeasily available in patients with lymphedema. We recommend the further study and clinicaluse of this tissue as it exhibits important properties and qualities for future applications andresearch.

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