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      • KCI등재

        Effect of Carbon-Doping on Microstructure and Nanomechanical/Tribological Behavior of Ti–B–C Coatings onto H13 Steel

        E. Contreras,D. Grisales,W. Tillmann,A. Hurtado‑Macias,M. A. Gómez‑Botero 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.8

        Due to its high hardness, chemical and thermal resistance, TiB2has become a great candidate to be used as a protective coating. However, high residual stresses after the deposition and brittleness have become the main obstacles for implementation atindustrial levels. In the present work, the incorporation of graphite was studied as an alternative to improve the performanceof the TiB2coatings and study the influence in the microstructure, Nano mechanical and tribological properties. Ti–B–Ccoatings were deposited with different carbon contents of 10, 20, 28 and 38 at%. XRD results showed that the carbon atomsenter within the crystal lattice of the TiB2forming a solid solution, and consequently, deforming crystal and modifying itslattice parameter of 3.2237–3.3414 Å. HRTEM images and selected area electron diffraction patterns analysis display thelow crystallite or degree of amorphosity due to the carbon concentration (C1.9 mol). Compressive residual stresses decreasein the coatings containing the higher amounts of carbon. The formation of a TiB2-C solid solution contributed to the incrementof nanohardness (H = 25 GPa) and improvement of the resistance to plastic deformation (H3/E2) of coatings. Regardingthe tribological behaviour of the coatings, higher friction coefficient than those obtained on the uncoated substrate wereobserved. However, a reduction of the wear rate was also evident. The presence of a high amount of debris and severe wearof the counterpart material indicates a highly aggressive tribological contact. Roll-like debris with a shape of needles wasfound within the tribological tracks perpendicular to the sliding direction.

      • SCIESCOPUSKCI등재

        Effect of mechanical alloying on the microstructural evolution of a ferritic ODS steel with (Y-Ti-Al-Zr) addition processed by Spark Plasma Sintering (SPS)

        Macia, E.,Garcia-Junceda, A.,Serrano, M.,Hong, S.J.,Campos, M. Korean Nuclear Society 2021 Nuclear Engineering and Technology Vol.53 No.8

        The high-energy milling is one of the most extended techniques to produce Oxide dispersion strengthened (ODS) powder steels for nuclear applications. The consequences of the high energy mill process on the final powders can be measured by means of deformation level, size, morphology and alloying degree. In this work, an ODS ferritic steel, Fe-14Cr-5Al-3W-0.4Ti-0.25Y<sub>2</sub>O<sub>3</sub>-0.6Zr, was fabricated using two different mechanical alloying (MA) conditions (M<sub>std</sub> and M<sub>act</sub>) and subsequently consolidated by Spark Plasma Sintering (SPS). Milling conditions were set to evidence the effectivity of milling by changing the revolutions per minute (rpm) and dwell milling time. Differences on the particle size distribution as well as on the stored plastic deformation were observed, determining the consolidation ability of the material and the achieved microstructure. Since recrystallization depends on the plastic deformation degree, the composition of each particle and the promoted oxide dispersion, a dual grain size distribution was attained after SPS consolidation. M<sub>act</sub> showed the highest areas of ultrafine regions when the material is consolidated at 1100 ℃. Microhardness and small punch tests were used to evaluate the material under room temperature and up to 500 ℃. The produced materials have attained remarkable mechanical properties under high temperature conditions.

      • SCISCIESCOPUS

        Mutations in <i>MAPKBP1</i> Cause Juvenile or Late-Onset Cilia-Independent Nephronophthisis

        Macia, Maxence S.,Halbritter, Jan,Delous, Marion,Bredrup, Cecilie,Gutter, Arthur,Filhol, Emilie,Mellgren, Anne E.C.,Leh, Sabine,Bizet, Albane,Braun, Daniela A.,Gee, Heon Y.,Silbermann, Flora,Henry, Ch University of Chicago Press [etc.] 2017 American journal of human genetics Vol.100 No.2

        <P>Nephronophthisis (NPH), an autosomal-recessive tubulointerstitial nephritis, is the most common cause of hereditary end-stage renal disease in the first three decades of life. Since most NPH gene products (NPHP) function at the primary cilium, NPH is classified as a ciliopathy. We identified mutations in a candidate gene in eight individuals from five families presenting late-onset NPH with massive renal fibrosis. This gene encodes MAPKBP1, a poorly characterized scaffolding protein for JNK signaling. Immunofluorescence analyses showed that MAPKBP1 is not present at the primary cilium and that fibroblasts from affected individuals did not display ciliogenesis defects, indicating that MAPKBP1 may represent a new family of NPHP not involved in cilia-associated functions. Instead, MAPKBP1 is recruited to mitotic spindle poles (MSPs) during the early phases of mitosis where it colocalizes with its paralog WDR62, which plays a key role at MSP. Detected mutations compromise recruitment of MAPKBP1 to the MSP and/or its interaction with JNK2 or WDR62. Additionally, we show increased DNA damage response signaling in fibroblasts from affected individuals and upon knockdown of <I>Mapkbp1</I> in murine cell lines, a phenotype previously associated with NPH. In conclusion, we identified mutations in <I>MAPKBP1</I> as a genetic cause of juvenile or late-onset and cilia-independent NPH.</P>

      • KCI등재

        Design and experimental evaluation of a mixed-mode continuous solar dryer for plaster molds

        K. M. Aguilar-Castro,J. J. Flores-Prieto,M. E. Baltazar-Lopez,E. V. Macias-Melo 대한기계학회 2012 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.26 No.9

        This work aimed to develop and evaluate a mixed-mode continuous solar dryer for plaster molds for the local craft ceramics industry to reduce the drying time during the pottery manufacturing process. This novel design reduces time and movements in the manufacturing line. Indirect solar energy is used to complement direct solar energy; such a combination allows the continuous drying process to meet the energy requirements and optimize solar energy expenses. The experimental results show that the average evaporation rate is 0.7 kg/hr,the average energy consumption is 2.57 MJ/kg-H2O-evaporated, and the drying time is 4 days. The actual drying time represents 20% to 29% of the total foregoing time employed by Morelos-México craft potters. This finding indicates that the dryer continuously works using 66.4% indirect and 33.6% direct solar energy, thereby entailing lower expenses than traditional continuous drying processes.

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