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RISS 인기검색어
- 검색키워드
- 저자 : M. A. Basher (검색결과 3 건)
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Mahmoud, Ayman M.,Alqahtani, Sultan,Othman, Sarah I.,Germoush, Mousa O.,Hussein, Omnia E.,Al-Basher, Gadh,Khim, Jong Seong,Al-Qaraawi, Maha A.,Al-Harbi, Hanan M.,Fadel, Abdulmannan,Allam, Ahmed A. Hindawi 2017 Oxidative medicine and cellular longevity Vol.2017 No.-
<P>Hyperammonemia is a serious complication of liver disease and may lead to encephalopathy and death. This study investigated the effects of <I>Commiphora molmol</I> resin on oxidative stress, inflammation, and hematological alterations in ammonium chloride- (NH<SUB>4</SUB>Cl-) induced hyperammonemic rats, with an emphasis on the glutamate-NO-cGMP and Nrf2/ARE/HO-1 signaling pathways. Rats received NH<SUB>4</SUB>Cl and <I>C. molmol</I> for 8 weeks. NH<SUB>4</SUB>Cl-induced rats showed significant increase in blood ammonia, liver function markers, and tumor necrosis factor-alpha (TNF-<I>α</I>). Concurrent supplementation of <I>C. molmol</I> significantly decreased circulating ammonia, liver function markers, and TNF-<I>α</I> in hyperammonemic rats. <I>C. molmol</I> suppressed lipid peroxidation and nitric oxide and enhanced the antioxidant defenses in the liver, kidney, and cerebrum of hyperammonemic rats. <I>C. molmol</I> significantly upregulated Nrf2 and HO-1 and decreased glutamine and nitric oxide synthase, soluble guanylate cyclase, and Na<SUP>+</SUP>/K<SUP>+</SUP>-ATPase expression in the cerebrum of NH<SUB>4</SUB>Cl-induced hyperammonemic rats. Hyperammonemia was also associated with hematological and coagulation system alterations. These alterations were reversed by <I>C. molmol</I>. Our findings demonstrated that <I>C. molmol</I> attenuates ammonia-induced liver injury, oxidative stress, inflammation, and hematological alterations. This study points to the modulatory effect of <I>C. molmol</I> on glutamate-NO-cGMP and Nrf2/ARE/HO-1 pathways in hyperammonemia. Therefore, <I>C. molmol</I> might be a promising protective agent against hyperammonemia.</P>
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On the Folding of the Rectangular Distribution
El-Shehawy, S.A.,Basher, M. Department of Mathematics 2013 Kyungpook mathematical journal Vol.53 No.1
Based on the concept of the folding, the folding in X-direction and in Y-direction are defined and denoted by the X-Folding and the Y-Folding respectively. We consider a random variable X which follows a rectangular distribution "R(a, b) distribution" with two parameters a, b. This paper aims to apply the folding on the unit area P($a{\leq}X{\leq}b$) and also to study the proposed folding in each direction for R(a, b) distribution and the generated family of the corresponding constructed rectangular probability distributions. Some main properties of this family are reviewed. According to the proposed folding, we derive and discuss some important corresponding functions in closed forms.
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Ultimate load behavior of horizontally curved composite plate girders
N. E. Shanmugam,M. A. Basher,A. R. Khalim 국제구조공학회 2009 Steel and Composite Structures, An International J Vol.9 No.4
This paper is concerned with steel-concrete composite plate girders curved in plan. At the design stage these girders are assumed sometimes to act independent of the deck slabs resting on them in order to simplify the analysis. The advantage of composite action between the steel girders and concrete deck is not utilized. Finite element modeling of such composite action in plate girders is considered in this paper. Details of the finite element modeling and the non-linear analysis of the girders are presented along with the results obtained. Tension field action in the web panels similar to those observed in the straight plate girders is also noticed in these girders. Finite element and experimental results in respect of curved steel plate girders and straight composite plate girders tested by other researchers are presented first to assess the accuracy of the modeling. Effects of parameters such as curvature, steel flange width and web panel width that affect the behavior of composite girders are then considered in the analyses. An approximate method to predict the ultimate strength of horizontally curved composite plate girders is also presented.
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