http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Expression and Prognostic Implications of FOXO3a and Ki67 in Lung Adenocarcinomas
Liu, Hong-Bin,Gao, Xiang-Xiang,Zhang, Qing,Liu, Jian,Cui, Yuan,Zhu, Yan,Liu, Yi-Fei Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.4
To investigate the significance of FOXO3a and Ki67 in human lung adenocarcinomas. Envision immunohistochemical staining and Western blotting were used to examine the protein expression of FOXO3a in 127 cases of human lung adenocarcinoma specimens. The positive rate in lung adenocarcinoma (55.9%) was lower than that in normal tissues (80%). We found that the expression of FOXO3a was closely related with the degree of differentiation, TNM staging, lymph node metastasis and survival. In addition, significant differences in the different pathological types of lung adenocarcinoma cases (P<0.01). The FOXO3a positive rate of the acini as the main type (APA) (86.7%) and the lepidic as the main type (LPA) (82.4%) was higher than the solid as the main type (SPA) (50.0%), the papilla as the main type (PPA) (42.9%) and the micropapilla as the main type (MPA) (9.4%). Moreover, the expression of FOXO3a was negatively related with Ki67 expression. Our results suggested that the expression of FOXO3a is closely correlated with the aggressiveness of lung adenocarcinoma. It was indicated that disregulation of FOXO3a might play key roles in the occurrence and development of lung a denocarcinoma and joint detection of the two markers might play an important role in diagnosing tumors.
REDUCING SUBSPACES OF A CLASS OF MULTIPLICATION OPERATORS
Liu, Bin,Shi, Yanyue Korean Mathematical Society 2017 대한수학회보 Vol.54 No.4
Let $M_{z^N}(N{\in}{\mathbb{Z}}^d_+)$ be a bounded multiplication operator on a class of Hilbert spaces with orthogonal basis $\{z^n:n{\in}{\mathbb{Z}}^d_+\}$. In this paper, we prove that each reducing subspace of $M_{z^N}$ is the direct sum of some minimal reducing subspaces. For the case that d = 2, we find all the minimal reducing subspaces of $M_{z^N}$ ($N=(N_1,N_2)$, $N_1{\neq}N_2$) on weighted Bergman space $A^2_{\alpha}({\mathbb{B}}_2)$(${\alpha}$ > -1) and Hardy space $H^2({\mathbb{B}}_2)$, and characterize the structure of ${\mathcal{V}}^{\ast}(z^N)$, the commutant algebra of the von Neumann algebra generated by $M_{z^N}$.
Single nucleotide polymorphism-based analysis of the genetic structure of Liangshan pig population
Liu, Bin,Shen, Linyuan,Guo, Zhixian,Gan, Mailing,Chen, Ying,Yang, Runling,Niu, Lili,Jiang, Dongmei,Zhong, Zhijun,Li, Xuewei,Zhang, Shunhua,Zhu, Li Asian Australasian Association of Animal Productio 2021 Animal Bioscience Vol.34 No.7
Objective: To conserve and utilize the genetic resources of a traditional Chinese indigenous pig breed, Liangshan pig, we assessed the genetic diversity, genetic structure, and genetic distance in this study. Methods: We used 50K single nucleotide polymorphism (SNP) chip for SNP detection of 139 individuals in the Liangshan Pig Conservation Farm. Results: The genetically closed conserved population consisted of five overlapping generations, and the total effective content of the population (Ne) was 15. The whole population was divided into five boar families and one non-boar family. Among them, the effective size of each generation subpopulation continuously decreased. However, the proportion of polymorphic markers (P<sub>N</sub>) first decreased and then increased. The average genetic distance of these 139 Liangshan pigs was 0.2823±0.0259, and the average genetic distance of the 14 boars was 0.2723±0.0384. Thus, it can be deduced that the genetic distance changed from generation to generation. In the conserved population, 983 runs of homozygosity (ROH) were detected, and the majority of ROH (80%) were within 100 Mb. The inbreeding coefficient calculated based on ROH showed an average value of 0.026 for the whole population. In addition, the inbreeding coefficient of each generation subpopulation initially increased and then decreased. In the pedigree of the whole conserved population, the error rate of paternal information was more than 11.35% while the maternal information was more than 2.13%. Conclusion: This molecular study of the population genetic structure of Liangshan pig showed loss of genetic diversity during the closed cross-generation reproduction process. It is necessary to improve the mating plan or introduce new outside blood to ensure long-term preservation of Liangshan pig.
( Liu Bin ),( Ning Ning Zhang ),( Chao Zhao ),( Bai Xue Lin ),( Lian Hui Xie ),( Yi Fan Huang ) 한국미생물 · 생명공학회 2012 Journal of microbiology and biotechnology Vol.22 No.10
A xylanase-producing thermophilic strain, Geobacillus sp. TC-W7, was isolated from a hot spring in Yongtai (Fuzhou, China). Subsequently, the xylanase gene that encoded 407 amino acids was cloned and expressed. The recombinant xylanase was purified by GST affinity chromatography and exhibited maximum activity at 75℃ and a pH of 8.2. The enzyme was active up to 95℃ and showed activity over a wide pH range of 5.2 to 10.2. Additionally, the recombinant xylanase showed high thermostability and pH stability. More than 85% of the enzyme`s activity was retained after incubation at 70℃ for 90 min at a pH of 8.2. The activity of the recombinant xylanase was enhanced by treatment with 10 mM enzyme inhibitors (DDT, Tween-20, 2-Me, or TritonX-100) and was inhibited by EDTA or PMSF. Its functionality was stable in the presence of Li+, Na+, and K+, but inhibited by Hg2+, Ni2+, Co2+, Cu2+, Zn2+, Pb2+, Fe3+, and Al3+. The functionality of the crude xylanase had similar properties to the recombinant xylanase except for when it was treated with Al2+ or Fe2+. The enzyme might be a promising candidate for various industrial applications such as the biofuel, food, and paper and pulp industries.
Protection of Suburb Green Space: Contradiction of Protection and Use
Liu Bin-Yi,Xing Yang Korean Institute of Landscape Architecture 2004 Journal of the Korean institute of landscape archi Vol.2 No.-
This paper preliminary discussed the important function and faced problems of suburb green space during the process of urban development. As well as it points out the contradiction of protection and making use of. In this paper it takes the green space system planning in Wuxi as an example. Through introducing the classification, distribution, arrangement principles, overall arrangement tactics and concrete protective measures of suburb green space in Wuxi, the paper also puts forward the correct disposal principles for the relationship between protection and making use of toward the suburb green space to realize 'both-win' of them.
Bin Xie,Jie Li,Lianggui Liu 보안공학연구지원센터 2014 International Journal of Multimedia and Ubiquitous Vol.9 No.12
Enhanced Distributed Channel Access (EDCA) mechanism is used in WLAN to support QoS for various multimedia service flows. IEEE 802.11e EDCA introduces some new QoS parameters based on DCF. How to adjust these parameters is a significant problem. In the paper, we present a novel saturated throughput analysis of the IEEE 802.11e EDCA. This approach involves a novel analytical model that is an extension to previous works, which provide Markov chain analysis to IEEE 802.11e EDCA. Throughput analysis of our model is evaluated by comparison with NS2 simulations. We found the model is correct and suitable for both basic access and request-to-send/clear-to-send (RTS/CTS) access mechanisms.
A J2EE based Management Information System for Higher Vocational Colleges
Bin Lu,Changyu Liu,Cong Li 보안공학연구지원센터 2015 International Journal of Smart Home Vol.9 No.1
Informatization has always been one core competency for effective daily management. Although there are various types of management information systems available, few of them could take into account ever changing management requirements of higher vocational colleges. In this paper, we develop a J2EE based management information system for higher vocational colleges. Firstly, we perform an overview of the entire background and situation of the management informatization for higher vocational colleges. Secondly, according to requirement analysis and use case analysis, we divide the system, which requires three roles, i.e., college administrator, enterprise and graduate, into four functional modules, i.e., user login module, college administrator module, graduate module and enterprise module. Thirdly, for architecture design, we adopt a J2EE four-tier architecture, which are user presentation tier, control treatment tier, business logic tier and data persistence tier. Then, we introduce five entities, which are user information table, enterprise information table, graduate information table, recruitment information table and dynamic news table, for the database design. Furthermore, we also illustrate how we implement the final system.
Bin Liu,Changfeng Yan,Zonggang Wang,Yaofeng Liu,Lixiao Wu 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.7
Deep learning is widely used in the field of rolling bearing fault diagnosis because of its excellent advantages in data analysis. However, in practical industrial scenarios, the capability of intelligent fault diagnosis (IFD) method is still affected by two problems: (1) The signal samples provided for network learning are limited; (2) Fully extracting feature information from the original data is difficult. To address the above issues, a novel fault diagnosis method using joint learning network (JLNet) based on local-global feature perception is proposed. The method enhances the learning mechanism of fault signal through the local information dynamic perception subnetwork, which dynamically distinguishes between local impulse segment and normal signal segment. Then, a global channel attention mechanism (CAM) is used to guide the assignment of weights, which helps bidirectional gated recurrent unit (BiGRU) to learn advanced discriminative features. The feature information of the original signal is thoroughly mined through local-global comprehensive perception, thus realizing efficient diagnosis. In addition, the variation of the characteristics of each layer is analyzed by visualization, which improves the interpretability of the network. Finally, experiments are conducted using two different datasets, and the results show that JLNet has a better diagnostic effects and robustness.