임신중 산전 초음파로 진단된 자궁근종의 임상적 고찰

서정호,김윤숙,김대원,이동운,최규연,이정재,이임순 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.1

Objectives: To study the clinical manifestations; time, mode of delivery, size of myomas and outcome of pregnancy in cases of myomas that were detected prior to pregnancy or during the antenatal care and after delivery. Methods: We statistically analyzed 76 patients with uterine myomas in pregnancy admitted to Soonchunhyang Seoul Hospital during the period of Jan. 1999 and Dec. 2001. Results: The results are as follows. 1. The mean age of patients in the detected group and undetected group were 32.9 years and 32.3 years, respectively. There was no difference in the proportion of primarity between the detected group(98.2%) and the undetected group(79.6%) 2. The most common type of uterine myoma in both groups was intramural myoma (detected group 94.1% vs undetected group 81.3%). The uterine myomas were most commonly located in the anterior portion and fundus(detected group 52.9% and 23.5% respectively vs undetected group 47.4% and 23.7% respectively) and the proportion was not significantly different between the two groups. Uterine myomas with a diameter of 3cm or more in the detected group were detected by clinical examination and ultrasonogram. Rate of uterine myomas with a diameter of 3cm or more in the detected group is 76.5% and less than 3cm is 54.2% which detected incidentally at delivery. 3. The proportion of term infants were detected group 88.2% vs undetected group 91.5%. 4. The most common indications for cesarean section in both groups were cephalopelvic disproportion and repeated cesarean section (detected group 41.2% and 45.8% respectively vs undetected group 11.8% and 18.6% respectively) and there was no significant difference between the two groups. 5. Secondary pathologic changes in the all myomectomy specimens were degeneration in both groups but there was no necrosis or sarcomatous change. 6. Antenatal complications were preterm labor, premature repture of membranes, spontaneous abortion, malpresentation, and placenta previa. Intrauterine growth retardation and placental abruption were not seen in both groups. Conclusion: Myoma detected by ultrasonogram before or during pregnancy is not a significant implication of pregnancy outcome.

고혈압 환자에서 경동맥 신전성의 변화

허영선,김학진,송영빈,안지현,임성훈,이왕수,김상욱,김태호,김치정,류왕성,유언호 중앙대학교 의과대학 의과학연구소 2000 中央醫大誌 Vol.25 No.3

METRIZABILITY FOR THE AUTOHOMEOMORPHISM GROUP OF A METRIC SPACE

LIM, HO-UN,LIM, PYUNG-KI 圓光大學校 基礎自然科學硏究所 1995 基礎科學硏究誌 Vol.14 No.1

거리위상공간 X위에서 정지된 자기위상동형사상들의 공간 H(X)는 위상군을 이룬 다. Y가 X의 compact 부분공간이면 H(Y)는 거리화 가능함을 이용하여 X가 Hemi-compact 일 때 H(X)가 거리공간임을 증명한다. Let X and Y be topological spaces and C(X,Y) the set of all continuous mappings from X into Y. It will be convenient to topologize C(X,Y) and interesting subsets of it with a natural topology. Unfortunately, there are many Ways to do that. In this paper, all spaces are assumed to be metrizable and we shall discuss only the compact open topology on C(X,Y). Let H(X,Y) denote the set of all homeomorphisms from X onto Y considered as a subspace of (X,Y). If X is equal to Y then for H(X,Y). We shall simply write H(X) and call this the autohomeomorphism group of X. The aim of this note is to prove the following theorem ; 〔Theorem A〕. If a space X is hemi-compact, Then H(X) is metrizable.

SOME PROPERTIES OF G-SPACES

LIM, HO-UN,LIM, PYUNG-KI 圓光大學校 基礎自然科學硏究所 1995 基礎科學硏究誌 Vol.14 No.1

본 논문에서는 G가 유한군일때 G-공간의 여러 명제들과 또한 위상군의 동차 성, Compact 성, 고정점집합의 조건에서 G-공간의 성질들을 증명한다. The theory of G-spaces and topological groups is very useful to study many branches of mathematics. In this paper, we prove some propositions for G-spaces under the condition that G is a finite group, investigate theorems using the homeogeneity and the symmetric neighborhoodness of compact topological group, and verify the closedness for the invariant of a Hausdorff G-space.

Hepatic Resection for Hepatic Metastases from Gastric Adenocarcinoma

Baek, Hyoung-Un,Kim, Sang Bum,Cho, Eung-Ho,Jin, Sung-Ho,Yu, Hang Jong,Lee, Jong-Inn,Bang, Ho-Yoon,Lim, Chang-Sup The Korean Gastric Cancer Association 2013 Journal of gastric cancer Vol.13 No.2

Purpose: The effects of hepatic resection on patients with metastatic tumors from gastric adenocarcinomas are unclear. Therefore, we analyzed early clinical outcomes in patients who underwent surgical resection for hepatic metastases from gastric adenocarcinomas. Materials and Methods: From January 2003 to December 2010, 1,508 patients with primary gastric cancers underwent curative gastric resections at the Korea Cancer Center Hospital. Of these patients, 12 with liver-only metastases underwent curative hepatic resection. Their clinical data were analyzed retrospectively. Results: The median follow-up period was 12.5 months (range, 1~85 months); no operative mortalities or major complications were observed. Three patients underwent synchronous resections, and 9 underwent metachronous resections. In the latter group, the median interval between gastrectomy and hepatectomy for hepatic metastasis was 10.5 months (range, 5~47 months). The overall 1- and 5-year survival rates of these 12 patients were 65% and 39%, respectively, with a median overall survival of 31.0 months; 2 patients survived for >5 years. Conclusions: Hepatic resection can be a feasible procedure for treating hepatic metastases from gastric adenocarcinomas. Although this study was small and involved only selected cases, the outcomes of the hepatic resections were comparable and long-term (>5 years) survivors were identified. Surgical resection of the liver can be considered a feasible option in managing hepatic metastases from gastric adenocarcinomas.

고전압 펄스 전기장 처리가 사과의 착즙 특성에 미치는 영향

임정호 ( Jeong Ho Lim ),안성환 ( Seong Hwan Ahn ),이동언 ( Dong Un Lee ),김영호 ( Young Ho Kim ),박기재 ( Kee Jai Park ) 한국식품저장유통학회(구 한국농산물저장유통학회) 2012 한국식품저장유통학회지 Vol.19 No.5

The effects of pretreatment by pulsed electric fields (PEFs) on the juice expression characteristics of the Malus pumila fruit were investigated. Fresh fruits were divided into quarters, were produced on a laboratory scale (100 g apples per lot) by pretreatment with electric fields at two different field intensities (1, 2 kV/cm; n=50, 100, 200, and 400 pulses), and were then pressed at room temperature. Relative to the control samples, the juice yield increased with increasing field intensities. The total phenolics and antioxidant activity were higher in the juice from the PEF-treated fruit than in the juice from the untreated fruit. There was no significant difference in soluble-solid and reducing sugar contents between the PEF-treated and untreated fruits. These results suggest that PEF pretreatment may be useful for increasing the juice yield, total phenolics, and antioxidant activity of the Malus pumila fruit.

백삼의 건조와 가용성 성분 추출에 미치는 pulsed electric fields(PEF)의 효과

임정호(Jeong Ho Lim),심재민(Jae Min Shim),이동언(Dong Un Lee1),김영호(Young Ho Kim),박기재(Kee-Jai Park) 한국식품과학회 2012 한국식품과학회지 Vol.44 No.6

식품의 가공공정에서 투입되는 에너지의 절감을 위한 방안으로 대표적이 농산물 건조제품인 인삼의 건조과정에서 PEF를 처리함으로써 건조효율에 미치는 영향과 PEF를 처리하여 건조한 인삼인 백삼의 열수 추출과정에서의 추출효율에 미치는 영향을 분석하였다. 4년근 수삼을 2 kV/cm, 200 Hz, 7초의 조건으로 PEF를 처리하여 55±1℃에서 건조한 결과 건조시간을 약 38% 단축시킬 수 있는 결과를 얻었다. 건조한 백삼을 95±1℃로 추출한 결과 무처리에 비해 2 kV/cm, 25 Hz, 7초간 PEF 처리한 건조 백삼, 2 kV/cm, 200 Hz, 7초간 PEF 처리하여 건조한 백삼의 열수 추출물의 고형분 함량, 환원당 함량, 유리당 함량 등에서는 유의적인 차이를 나타내었으나 당도와 진세노사이드 함량에서는 부분적인 유의적 차이만을 나타내었다. 이러한 결과를 감안할 때 수삼에 PEF를 처리함으로써 건조시간을 효과적으로 단축시킬 수 있고 추출시에도 가용성 고형분의 추출시간을 단축할 수 있는 유용한 수단이 될 수 있을 것으로 판단된다. This study was designed to investigate the effect of pulsed electric fields on the drying of ginseng and extraction of dried ginseng to reduce energy-consumption. Fresh ginseng was treated in a PEF system of 1 and 2 kV/cm electric field strength, 25 and 200 Hz of frequency, 30 μs of pulse width and pulse number of 175. The samples were subsequently dried for 26 h at 55±1℃, and the characteristic of hot-water extraction on dried ginseng was investigated. The ginseng pretreated with an intensity of 2 kV/cm (200 Hz, n=175) resulted in a reduction of approximately 38% for drying time. The influence of PEF treatment on the water extraction of dried ginseng at 95±1℃ was also investigated. The application of an electric field intensity of 2 kV/cm (25 and 200 Hz, n=175) increased soluble solid content, significantly reducing sugar content and free sugar content of the extract compared to non-PEF-treated samples.

Thrombospondins Mediate the Adhesion of Osteoblast to Extracelluar Matrix

Lim, Dong-Jin,Bae, In-Ho,Jeong, Byung-Chul,Kim, Sun-Hun,Park, Bae-Keun,Kang, Un-Chul,Lee, Shee-Eun,Song, Sang-Hun,Koh, Jeong-Tae KOREAN ACADAMY OF ORAL BIOLOGY 2008 International Journal of Oral Biology Vol.33 No.3

Thrombospondins (TSP-l, TSP-2) are secretory extracellular glycoproteins that are involved in a variety of physiological processes such as tumor cell adhesion, invasion, and metastasis. The present study was undertaken to elucidate the involvement of thrombospondins in the adhesion of osteoblast-like cells using the TSP-l or TSP-2 antisense MG63 and MC3T3-El cell lines. For downregulation of TSPs expression, we prepared antisense constructs for TSP-l and TSP-2 using the pREP4 an episomal mammalian expression vector, which be able to produce the specific antisense oligonucleotides around chromosome. MG63 and MC3T3-El osteoblast-like cells were transfected with the antisense constructs and nonliposomal Fugene 6, and then selected under hygromycin B (50 μg/ml) treatment for 2 weeks. Western blot analysis revealed that expression of the TSP proteins was downregulated in the antisense cell lines. The cell adhesion assay showed that adhesive properties of TSP-l and TSP-2 antisense MG63 cells on the polystyrene culture plate were reduced to 17% and 21% of the control cells, respectively, and those of the TSP-l and TSP-2 antisense MC3T3-El cells also decreased to 19% and 27% of control, respectively. Adhesion of TSP-l and TSP-2 antisense MC3T3-El cells on Type I collagen-coated culture plate decreased to 27% and 76%, respectively. These results indicate that TSP-l and TSP-2 proteins may have an important role in adhesion of osteoblast-like cells to extracellular matrix.

리스페리돈과 올란자핀이 투여된 정신과 환자들에서 간 효소 변화에 대한 후?적 연구

임현국,배치운,박석준,김정진,이창욱,이수정,이철,백인호 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.3

Effects of Ambroxol, S-carboxymethylcysteine, Dextromethorphan and Noscapine on Mucin Release from Airway Goblet Cells

Ho Jin Heo,Hyun Jae Lee,Chi Soon Yoon,Seung Pyong Lim,Jeong Ho Seok,Un Kyo Seo,Choong Jae Lee 대한생리학회-대한약리학회 2005 The Korean Journal of Physiology & Pharmacology Vol.9 No.6

In the present study, we investigated whether ambroxol, S-carboxymethyl-L-cysteine, dextromethorphan and noscapine affect mucin release from airway goblet cells. Confluent primary hamster tracheal surface epithelial cells were metabolically radiolabeled and chased for 30 min in the presence of varying concentrations of the above agents to assess the effects on <SUP>3</SUP>H-mucin release. Noscapine stimulated mucin release during 30 min of treatment period in a dose-dependent manner. However, ambroxol, S-carboxymethyl-L-cysteine and dextromethorphan showed no significant effect on mucin release during 30 min of treatment period. We conclude that noscapine can affect mucin release by acting on airway mucin-secreting cells.