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      • 방사선 센서의 동작특성

        임영화,한상효,김도성,강희동 경북대학교 센서기술연구소 1995 센서技術學術大會論文集 Vol.6 No.1

        A Geiger-M□ller(GM) radiation sensor is fabricated by using the vacuum system and gas feeding system. The base pressure of the vacuum system is 1X10^(-7)torr, and two MFCs(0~10sccm, ±1% accuracy of the full scale) are used to control the composition of filling gas exactly. The fabricated GM radiation sensor is simultaneously filled with the mixture of neon and clorine. The mica window(7.43mg/cm^(2)) is attached to the GM radiation sensor. The optimized GM radiation sensor has about 660V starting voltage, 125V plateua length, and 10%/100V plateau slope.

      • 12-O-Tetradecanoylphorbol-13-Acetate에 의한 HL-60 세포 분화유도중 Vimentin 유전자 전사조절에 대한 AP-1의 역할

        임규,김진희,권도원,김승민,이명선,윤경아,손미영,박종일,윤완희,황병두 忠南大學校 癌共同硏究所 1998 癌共同硏究所 硏究誌 Vol.2 No.1

        Purpose: To gain insight on the role of AP-1 in transcriptional regulation of vimentin gene during differentiation of HL-60 cells by 12-O-tetradecanoylphorbol-13-acetate (TPA), the levels of vimentin mRNA and AP-1 have been investigated with Northern blot hybridization and DNA mobility shift assay. Materials and Methods: HL-60 cells were grown in RPMI 1640 medium supplemented with 10% heat-inactivated fetal calf serum and antibiotics in a humidified 5% CO_(2) at 37°C. Total RNA was prepared by a modification of the method of Karlinsey et al. Northern blot hybridization was performed by the method of Virca et al. EcoRI fragment of pVIM-GEM was used as probe for vimentin mRNA. DNA mobility shift assay was performed by the method of Lim et al. End labeled DNA probe(Upper strand, 5'-CGCTTGATGAGTCAGCCG- 3') for AP-1 binding activity was mixed with nuclear extracts in a 20 μl reaction volume containing 300 mM KC1, 60 mM HEPES, pH 7.9, 25 mM MgCl_(2), 1 mM EDTA, 1 mM DTT, 60% glycerol, and 2μg of poly[dI-dC]. Results: TPA increased vimentin mRNA levels, with maximal stimulation reached at 24 hr. The level of vimentin mRNA was induced in proportion to the concentration of TPA. TPA-induced vimentin mRNA was almost reduced by actinomycin-D pretreatment. TPA-induced stimulation of vimentin gene was completely reduced by staurosporin pretreatment. In DNA mobility shift assay, AP-1 newly appeared at 24 hr during TPA-induced differentiation and was almost not detected after the pretreatment of staurosporin. Conclusions: These results suggest that the induction of vimentin mRNA during TPA-dependent differentiation in HL-60 cells may be mediated by protein kinases C signal transduction and AP-1 is important to transcriptional regulation.

      • 12-O-Tetradecanoylphorbol-13-Acetate에 의한 HL-60 세포 분화유도중 Vimentin 유전자 전사조절에 대한 AP-1의 역할

        임규,김진희,권도원,김승민,이명선,윤경아,손미영,박종일,윤완희,황병두 충남대학교 생물공학연구소 1999 생물공학연구지 Vol.7 No.-

        Purpose: To gain insight on the role of AP-1 in transcriptional regulation of vimentin gene during differentiation of HL-60 cells by 12-O-tetradecanoylphorbol-13-acetate (TPA), the levels of vimentin mRNA and AP-1 have been investigated with Northern blot hybridization and DNA mobility shift assay. Materials and Methods: HL-60 cells were grown in RPMI 1640 medium supplemented with 10% heat-inactivated fetal calf serum and antibiotics in a humidified 5% CO_2 at 37℃. Total RNA was prepared by a modification of the method of Karlinsey et al. Northern blot hybridization was performed by the method of Virca et al. EcoRI fragment of pVIM-GEM was used as probe for vimentin mRNA. DNA mobility shift assay was performed by the method of Lim et al. End labeled DNA probe(Upper strand, 5'-CGCTTGATGAGTCAGCCG- 3') for AP-1 binding activity was mixed with nuclear extracts in a 20 μl reaction volume containing 300 mM KCI, 60 mM HEPES, pH 7.9, 25 mM MgCI_2, 1 mM EDTA, 1 mM DTT, 60% glycerol, and 2 ㎍ of poly[dI-dC]. Results: TPA increased vimentin mRNA levels, with maximal stimulation reached at 24 hr. The level of vimentin mRNA was induced in proportion to the concentration of TPA. TPA-induced vimentin mRNA was almost reduced by actinomycin-D pretreatment. TPA-induced stimulation of vimentin gene was completely reduced by staurosporin pretreatment. In DNA mobility shift assay, AP-1 newly appeared at 24 hr during TPA-induced differentiation and was almost not detected after the pretreatment of staurosporin. Conclusions: These results suggest that the induction of vimentin mRNA during TPA-dependent differentiation in HL-60 cells may be mediated by protein kinases C signal transduction and AP-1 is important to transcriptional regulation.

      • MgO-Al₂O₃-SiO₂계 요업원료(Mullite,Spinel,Cordierite)의 제조 및 소결특성 : Ⅲ. 알콕사이드 졸-겔법에 의한 코디어라이트 미분말의 합성 Ⅲ.Preparation of Cordierite Fine Powder by an Alkoxide Sol-Gel Process

        이홍림,김세기,이온영,정원도,김창은,이희수 연세대학교 산업기술연구소 1989 논문집 Vol.21 No.1

        The gel powder of cordierite composition was prepared from Mg(NO₃)₂6H₂O, Al[ OCHCH₂(CH₃)₂] ₃ and Si(OC ₂??)₄ as sources of Mg, Al and Si-components, using isopropyl alcohol al a solvent and NH₄OH as a catalyst. Due to the difference of hydrolysis rates between Si(OC₂??)₄ and Al[ OCHCH₂(CH₃)₂]₃, the small amount of spinel was formed besides the main phase, cordierite, after clacining. At 900 ℃, μ-cordierite, the low temperature metastable form, was appeared but transformed to α-phase, the high stable form, when calcined at 1100 ℃ for 2h. The specific surface area and mean particle size of powder calcined at 600 ℃ for 2h were 62m²/g and 0.552μm, respectively. However, when acetylacetone was added to Al [OCHCH₂(CH₃)₂]₃ as a stabilizer, the transformation temperature was lowered about 80 ℃. The powder calcined at 600℃ was more porous than the former, resulting the specific surface area and mean particle size of the power to be 236 m²/g and 0.724μ m, respectively.

      • KCI우수등재

        도시경관에 있어서 높이기준유형별 건축물의 형태적 특징에 관한 연구

        김도년,임희지 대한건축학회 2004 대한건축학회논문집 Vol.20 No.8

        Height control is about providing light and air on the streets and managing urban cityscape In order to achieve these goals, major cities in foreign countries are administering various unique height control methods that are adaptable to the city And by examining the architectural characteristics of the cities with various height control methods the following conclusions have been made In most modern cities excluding European historical cities paris and Berlin height limits are eased and controlled by each lot based on the widths of the adjacent streets There is a tendency to lighten the height limits as the height is controlled improvement as it interrupts the continuity of streets results in excessive tall towers and produces abnormal form of buildings like slanted facets Cities like New York and Tokyo, which previously controlled the height by lot are now adopting height-controlling by district in order to create unified street landscapes Recently seoul has introduced block height limits a form of district height controlling methods but it seems that there is a need for various height limits in the areas of atypical urban tissue and of unique characteristics so that they can be applied to the whole city.

      • 예견퍼지 알고리즘을 사용한 트럭-트레일러의 자율주차 제어 시스템에 관한 연구

        손준익,박희경,박재현,강신출,임영도 東亞大學校 附設 情報通信硏究所 1999 情報通信硏究所論文誌 Vol.7 No.1

        본 논문에서는 예견퍼지 알고리즘을 사용하여 트럭-트레일러의 자율주차 제어 시스템의 시뮬레이션을 행한다. 트럭-트레일러의 전·후진 동특성 방정식을 설정하여 예견퍼지 제어기의 설계시에 사용하고, 새상 시스템으로도 사용한다. 제안한 알고리즘으로 시뮬레이션을 통해서 일정 지역내의 임의의 출발점에서 적절한 도중목표를 설정하여 전후진을 하면서 핸들조작 횟수가 적게 최종목표 위치에 잘 주차됨을 입증하였다.

      • KCI등재

        영상 정보를 이용한 자율 주차 시스템에 관한 연구

        김영민(Young-min Kim),강희정(Hee-jung Kang),방상우(Sang-woo Bang),임영도(Young-do Lim) 한국정보기술학회 2010 한국정보기술학회논문지 Vol.8 No.5

        Generally parking of the vehicle only driver sight and in compliance with an experience comes to do the spatial security which is caused by with judging distance and the camera which are accurate the various sensor, but it in recent times is caused by with technical advancement and leads was possible, parking was quicker and safely there made be a possibility of doing. So about unmanned parking the research vehicle with technical advancement and in standard to be advanced from the side which is various comes. In this paper the parking sector from the public parking lot or the formation parking market is clear and importance in the space where the unmanned camera is established in the parking sector depends in real-time image value and is parks autonomously. The camera which is established in the parking sector guard and the vehicle of parking space, recognized the object with real-time image processing and the vehicle wheel track angle in compliance with a image data and presumed Fuzzy-control led and in the four-wheel mobile robot and parking a production value and got applied accomplished.

      • 유착성 관절낭염 치료에 있어서 한방 치료와 양방 치료의 임상적 고찰 : 동서협진 모델 개발을 위한 기초 연구를 중심으로

        남동우,정인태,김주희,박유선,임사비나,이두익,이재동,이윤호,최도영 경희대학교 동서의학연구소 2006 東西醫學硏究所 論文集 Vol.2006 No.-

        Objectives : To observe the effect of acupuncture treatment and western medical treatment on frozen shoulder patients. Methods : 39 voluntary patients were randomly assigned to the Eastern treatment group(E group, n=22) and the Western treatment group(W group, n=17). The E group received acupuncture treatment on LI15, TE14, GB21 and Master Dong's acupuncture points, Shin-gwan and Gyun-joong, twice a week for 4 weeks. The W group received suprascapular nerve block, subacromial injection and trigger point injection, twice a week for 4 weeks. Both groups were instructed to practice self exercise during their daily lives. Evaluations were made before treatment and after treatment using Constant Shoulder Assessment(CSA), Shoulder Pain and Disability Index(SPADI) and the patient's satisfaction concerning the treatment was measured by Visual Analogue Scale(VAS). The obtained data were analyzed and compared. Results : The E group showed significant improvement(p<0.05) according to the CSA and SPADI. The patient's satisfaction scored 5.67 on a scale of 10. The W group showed significant improvement(p<0.05) according to the CSA and SPADI. The patient's satisfaction scored 7.73. But the difference between the two groups were insignificant according to CSA and SPADI. Conclusion : Both acupuncture and nerve block treatment significantly improved frozen shoulder. But the difference of the two treatments was insignificant.

      • SCIESCOPUSKCI등재

        Near-Normalized Gene Expression Profiles in Bladder With Detrusor Overactivity in Rats With Bladder Outlet Obstruction After Deobstruction

        Lee, Tack,Lim, U-Sung,Kang, Dong Hyuk,Jung, Hae-Do,Kim, Hyunzu,Choi, Bo-Hwa,Kang, Ju-Hee,Yoon, Sang-Min,Park, Chang-Shin Korean Continence Society 2017 International Neurourology Journal Vol.21 No.4

        <P><B>Purpose</B></P><P>The pathophysiological role of detrusor overactivity (DO) in the bladder, which is commonly observed in various bladder diseases, is not well understood. DO appears in bladder outlet obstruction (BOO), and may continue even after subsequent deobstruction. DO therefore provides an excellent opportunity to observe molecular biological changes.</P><P><B>Methods</B></P><P>In this study, to understand the molecular effects of persistent DO after BOO induction and deobstruction, we performed awake cystometry on female Sprague-Dawley rats divided into 4 groups: a sham group, a BOO group, a deobstructed group with DO after BOO (DDO), and a deobstructed group without DO after BOO (non-DDO). Total RNA was extracted from the bladder samples, and gene expression profiles were compared between the sham and model groups.</P><P><B>Results</B></P><P>DO was observed in 5 of the 6 rats (83%) in the BOO group, and in 6 of the 13 rats (46%) in the deobstructed group. The non-DDO group showed a significantly greater residual volume than the DDO group. Through a clustering analysis of gene expression profiles, we identified 7,532 common upregulated and downregulated genes, the expression of which changed by more than 2 fold. In the BOO group, 898 upregulated and 2,911 downregulated genes were identified. The non-DDO group showed 3,472 upregulated and 4,025 downregulated genes, whereas in the DDO group, only 145 and 72 genes were upregulated and downregulated, respectively.</P><P><B>Conclusions</B></P><P>Abnormal function and gene expression profiles in bladders after BOO were normalized in the BOO rats with DO after deobstruction, whereas in those without DO, abnormal function persisted and the gene expression profile became more abnormal. DO may play a protective role against the stress to the bladder induced by BOO and deobstruction as a form of adaptive neuroplasticity.</P>

      • KCI등재

        A Survey on the Status and the Importance of Initial History Taking in Dental Clinics in S Area

        ( Do-seon Lim ),( Im-hee Jung ),( Ae-jung Im ),( Hee-jung Lim ) 한국치위생과학회 2020 치위생과학회지 Vol.20 No.4

        Background: A comprehensive history taking at the first visit could be an important start of treatment. This study investigated the current status of the initial history taking for dental patients in S area, and the implementation and importance of the initial history taking process. Based on this, we intend to provide basic data for the development of organized and standardized questionnaires in dental clinics. Methods: In April 2019, 303 dental clinics in S area were targeted and special dental clinics (orthodontics, children, and disabled) were excluded. The questionnaire consisted of 29 items, including general characteristics, systemic disease history, dental history, oral health behaviors, and the data were obtained through self-administered questionnaire. Results: Initial history taking was mostly implemented using oral and questionnaire at the time of the first visit. Systemic disease history, dental history, and oral health behaviors differed in the work experience of the dental clinic staff. As a result of analyzing the importance according to implementation, there were significant differences in all questions except drug-related items. The importance of the questionnaire was highly recognized, but the reason it was not actually implemented was because of existing the questionnaire in the clinic and lack of time. Conclusion: Considering that the initial history taking implementation rate showed low, it is necessary to develop standardize a practical questionnaire and interview skills for dental clinics in the future. In addition, training programs should be provided to dental staff that can recognize the importance of initial history taking questionnaires and contribute to active implementation.

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