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        CFD simulation of coal-water slurry flowing in horizontal pipelines

        Liangyong Chen,Wenhao Pu,Changsui Zhao,Yufeng Duan 한국화학공학회 2009 Korean Journal of Chemical Engineering Vol.26 No.4

        An Eulerian multiphase approach based on kinetic theory of granular flow was used to simulate flow of coal-water slurries (CWS) in horizontal pipelines. The RNG k-ε turbulent model was incorporated in the governing equation to model turbulent two-phase flow with strong particle-particle interactions. In this model, the coal particles with bimodal distribution were considered as two solid-phase components, and the moment exchange between solid and liquid as well as that between solid and solid were accounted for. The model was firstly validated with pressure gradient and concentration profile data from the open literature, and then validated with pressure gradient data of the authors’ experiments. The effects of influx velocity, total influx concentration and grain composition were numerically investigated, and the results have displayed some important slurry flow characteristics, such as constituent particle concentration distribution and velocity distribution as well as pressure gradients, which are very difficult to display in the experiments. The results suggest that both gravity difference between large and small particles and strong particleparticle interaction had significant effects on concentration distribution as well as velocity distribution.

      • KCI등재

        Local resistance characteristics of highly concentrated coal-water slurry flow through fittings

        Meng Liu,Liangyong Chen,Yufeng Duan 한국화학공학회 2009 Korean Journal of Chemical Engineering Vol.26 No.2

        The local resistance characteristics of high concentration coal-water slurry (CWS) flowing through three types of local fittings, namely the gradual contractions, sudden contractions and 90o horizontal elbows, were investigated at a transportation test facility. Results show that the local resistance loss of gradual contractions decreases as the contraction angle increases. When pipe diameter ratio varies little, local resistance loss of sudden contractions changes insignificantly. There is an optimal value of bend diameter ratio, at which the local resistance loss of horizontal elbows is the least. As Reynolds number increases, the resistance coefficients of all the three fittings first reduce and then stabilize, while the three pipes have different ratio of equivalent length to pipe diameter Le/D behaviors, that is, Le/D of the gradual contractions decreases gradually and then keeps stable; that of the sudden contractions diminishes at first and then increases, and that of the horizontal elbows increases linearly.

      • Selective Radiotherapy after Distant Metastasis of Nasopharyngeal Carcinoma Treated with Dose-Dense Cisplatin plus Fluorouracil

        Liang, Yong,Bu, Jun-Guo,Cheng, Jin-ling,Gao, Wei-Wei,Xu, Yao-Can,Feng, Jian,Chen, Bo-Yu,Liang, Wei-Chao,Chen, Ke-Quan Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.14

        Purpose: To investigate the efficacy and safety of selective radiotherapy after distant metastasis of nasopharyngeal carcinoma (NPC) treated with dose-dense cisplatin plus fluorouracil. Materials and Methods: Eligible patients were randomly assigned to a study group treated with dose-dense cisplatin plus fluorouracil following selective radiotherapy and a control group receiving traditional cisplatin plus fluorouracil following selective radiotherapy according to a 1:1 distribution using a digital random table method. The primary endpoint was overall survival (OS). Secondary endpoints were progression-free survival (PFS), objective response rate, relapse or progression rate in the radiation field and treatment toxicity. Results: Of 52 patients in the study group, 20 cases underwent radiotherapy., while in the control group of 51 patients, 16 underwent radiotherapy. The median PFS, median OS, survival rates in 1, 2 and 3 years in study and control group were 20.9 vs 12.7months, 28.3 vs 18.8months, 85.2%vs 65.9%, 62.2% vs 18.3%, and 36.6%vs 5.2% (p values of 0.00, 0.00, 0.04, 0.00 and 0.00, respectively). Subgroup analysis showed that the median OS and survival rates of 1, 2, 3 years for patients undergoing radiotherapy in the study group better than that in control group( 43.2vs24.1 months, 94.1% vs 86.7%, 82.4% vs 43.3%, 64.7% vs 17.3%, (p=0.00, 0.57, 0.04 and 0.01, respectively). The complete response rate, objective response rate after chemotherapy and three months after radiotherapy, relapse or progression rate in radiation field in study group and in control group were 19.2% vs 3.9%, 86.5% vs 56.9%, 85% vs 50%, 95% vs 81.3% and 41.3% vs 66.7% (p =0.03, 0.00, 0.03,0.30, 0.01 respectively). The grade 3-4 acute adverse reactions in the study group were significantly higher than in the control group (53.8% vs 9.8%, p=0.00). Conclusions: The survival of patients benefits from selective radiotherapy after distant metastasis of NPC treated with dose-dense cisplatin plus fluorouracil.

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