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Kim, K.J.,Lee, T.H.,Kim, J.H.,Cho, N.Y.,Kim, W.H.,Kang, G.H. W. B. Saunders Co ; Centrum Philadelphia 2017 Human pathology Vol.67 No.-
<P>Deletion of the HSP110 T-17 mononucleotide repeat has recently been identified as a prognostic marker that is correlated with wild-type HSP110 (HSP110wt) expression in microsatellite instability-high (MSI-H) colorectal cancers. The aim of this study was to assess the correlation between deletion of the HSP110 T-17 repeat and expression of HSP110wt using DNA testing and immunohistochemistry and to determine the prognostic implications of HSP110 T-17 deletion in MSI-H advanced gastric cancers (GCs). The status of HSP110wt expression was evaluated by immunohistochemistry using an HSP110wt-specific antibody in 142 MSI-H advanced GCs. The size of the HSP110 T-17 repeat deletion was analyzed in 96 MSI-H advanced GCs; deletions were divided into small (0-2 base pairs) and large deletions (3-5 base pairs). Low and high expressions of HSP110wt were detected in 38 (26.8%) and 104 (73.2%) of the 142 cases, respectively. The HSP110 T-17 deletion was observed in 45 (46.9%) of the 96 MSI-H GC samples. Tumors with high expression of HSP110wt showed a tendency to have small or no deletion of HSP110 T-17. In Kaplan-Meier survival analysis, tumors with a large HSP110 T-17 deletion were associated with favorable overall survival and disease-free survival compared with those with small/no deletion of HSP110 T-17. However, HSP110 T-17 deletion size was not an independent prognostic factor in multivariate analysis. In summary, deletion of the HSP110 T-17 repeat was frequently observed in MSI-H GCs, and HSP110 T-17 deletion size was inversely correlated with HSP110wt expression status. Large HSP110 T-17 was not a prognostic indicator in MSI-H GCs. (C) 2017 Elsevier Inc. All rights reserved.</P>
김원배,정재훈,윤보현,이석인,김민선,오태근,조보연,이홍규,고창순 대한내분비학회 1994 Endocrinology and metabolism Vol.9 No.3
It is well known that normal pregnancy is accompanied by a rise in serum concentrations of thyroxine-binding globulin(TBG) and human chorionic gonadotropin (hCG). Alterations of biochemical parameters of thyroid function are recognized during gestation and sensitive tests to evaluate the alterations easily are required. Therefore, a cross-sectional study was undertaken in 140 healthy pregnant women to evaluate the efficacy of free T_4 measured by 2-step RIA compared to other thyroid function tests and to confirm the changes of thyroid function according to the stages of normal pregnancy. The sensitivities of free T_4 index, free T_4(by 2-step RIA), T_3 and TSH were realtively high(99.3%, 93.6%, 92.9%, 83.6%, respectively) compared to those of T_4 and T_3 bead upgake(49.3%, 21.4%) during all stages of pregnancy. There were positive correlations between free T_4 index and free T_4 or total T_4(r=0.68, r=0.72; p$lt;0.001). The values of free T_4 index sharply decreased from 3.22+-0.10(meam +-SEM) during 6th-12th week to an plateau after 16th-20th week of gestation(p$lt;0.01). The serum concentrations free T_4 and T_3 bead uptake also significantly decreased from 1.65+-0.05 ng/dl, 24.7+- 0.7% during 6th-12th week to an plateau after 16th-20th week of gestation, respectively(p$lt;0.001), No differences were found in the changes of serum concentrations of T_3, T_4 and TSH according to the stages of pregnancy. In conclusion, it is adequate to measure some tests including free T_4 index and free T_4 to evaluate thyroid function during pregnancy. The thyroid physiology and changes of thyroid function according to the stages of pregnancy should be considered in the interpretation of thyroid function status during pregnancy(J Kor Soc Endocrinol 9: 183-189, 1994).
육계사료와 식용유 정제 폐백토(Spent Bleaching Clay) 급여가 육계의 생산성에 미치는 영향
전해열,손장호,이길왕,김선구,강한석,신택순,조병욱,Jeon H. Y.,Son J. H.,Lee K. W.,Kim S. K.,Kang H. S.,Shin T. S.,Cho B. W. 한국가금학회 2005 韓國家禽學會誌 Vol.32 No.4
본 연구는 Spent Bleaching Clay(SBC)를 육계사료의 에너지 공급원으로 활용 가능성을 구명하기 위하여 실시하였다. 부화 직후의 120수의 병아리(한협 3호)를4처리 3반복, 반복당 10수(암수 각각 5수씩)를 Control(T1) 사료에 SBC를 $2.0\%(T2),\;4.0\%(T3)$ 및 $6.0\%(T4)$ 첨가한 4처리로 배치하였다. 시험사료 급여전 1주일은 시판사료를 급여하였다. 4주간의 시험 기간동안 증체중 및 사료 섭취량은 T3 및 T4 처리구에서 증가하는 경향이 인정되었다. 사료효율은 T3구에서 개선되는 경향이 인정되었다. 가슴살 및 다리살에서 치방산 조성을 사료의 처리에 따른 효과는 인정되지 않았다. 육계 초기 및 후기 사료 급여시 모두, 사료중의 건물, 조단백질 및 조지방 이용율은 T4 처리구가 다른 처리구에 비해서 유의하게 감소하였으며(p<0.05), 대사에너지가도 T4 처리구가 다른 3구에 비해서 유의하게 저하하였다(p<0.05). 사료중의 조회분의 이용율은 사료의 처리에 따른 차이는 인정되지 않았다. 결론적으로 본 시험의 결과 육계사료에 $2\~4\%$의 SBC첨가는 육계의 성장 및 사료효율 개선의 가능성이 있음이 사료된다. This study was conducted to evaluate the feasibility of spent bleaching clay(SBC) as an energy resource for meat type chicks. A total of one hundred twenty 1-d old broiler chicks(Han-hyop, No. 3) were divided into four groups and each group was assigned to one of the following diets: 0(T1), 2.0(T2), 4.0(T3) and $6.0\%$ SBC(T4). Each treatment had 3 replications of 10 birds. Before feeding experimental diets, they were fed a commercial diet for a week Body weight gain and feed intake tended to increase in T3 and T4, respectively. Feed efficiency(feed intake/ gain) tended to decrease in T3 compared to other groups. Fatty acid composition of breast and thigh meat was not significantly affected by feeding SBC. Utilization of dry matter, energy, crude protein and crude fat was lower in T4 than in the other groups during both starter and finisher periods(p<0.05). Crude ash utilization was not significantly affected by feeding dietary SBC. These results indicate that broiler diets may be supplemented with 2 to $4\%$ SBC without adverse effect on growth.
소화 효소 및 시간에 따른 고섬유소 사료의 In vitro 소화율 측정법
오서영(S. Y. Oh),이민영(M. Y. Lee),김재만(J. M. Kim),이지환(J. H. Lee),윤원(W. Yun),송태화(T. H. Song),정연근(Y. K. Cheong),조진호(J. H. Cho) 충북대학교 동물생명과학연구소 2015 동물생명과학연구 Vol.7 No.-
This study was conducted to investigate assay of high fiber diet in vitro digestibility according to digestive enzyme and time. Treatment of this study included: 1) CON (basic method) 2) T1 (sample amount: 2 times; enzyme level: 2 times) 3) T2 (sample amount: 2 times, enzyme level: 2 times, assay time: 1.5 times) 4) T3 (sample amount: 2 times, enzyme level: 2 times, assay time: 2 times). With regard to dry matter (DM), organic matter (OM) digestibility, T3 and CON were higher than T1 and T2 (P<0.05). Also, with regard to DM and OM digestibility by time of digestion, base was similar T2. In conclusion, in vitro digestibility was closely related to digestion time.
3차원 가상도시 모델에서 높이맵을 이용한 CNN 기반의 그림자 탐지방법
윤희진,김주완,장인성,이병대,김남기 한국인터넷정보학회 2019 인터넷정보학회논문지 Vol.20 No.6
Recently, the use of real-world image data has been increasing to express realistic virtual environments in various application fields such as education, manufacturing, and construction. In particular, with increasing interest in digital twins like smart cities, realistic 3D urban models are being built using real-world images, such as aerial images. However, the captured aerial image includes shadows from the sun, and the 3D city model including the shadows has a problem of distorting and expressing information to the user. Many studies have been conducted to remove the shadow, but it is recognized as a challenging problem that is still difficult to solve. In this paper, we construct a virtual environment dataset including the height map of buildings using 3D spatial information provided by VWorld, and We propose a new shadow detection method using height map and deep learning. According to the experimental results, We can observed that the shadow detection error rate is reduced when using the height map. 최근 교육, 제조, 건설 등 다양한 응용 분야에서 사실적인 가상환경을 표현하기 위하여 실세계 영상데이터를 활용하는 사례가 증가하고 있다. 특히, 스마트 시티 등 디지털 트윈에 대한 관심이 높아지면서, 항공 영상 등 실제 촬영한 영상을 이용하여 현실감 있는 3D 도시 모델을 구축하고 있다. 그러나, 촬영된 항공 영상에는 태양에 의한 그림자가 포함되어 있으며, 그림자가 포함된 3D 도시 모델은 사용자에게 정보를 왜곡시켜 표현하는 문제를 안고 있다. 그림자를 제거하기 위하여 그동안 많은 연구가 진행되었지만, 아직 까지 해결하기 어려운 도전적인 문제로 인식되고 있다. 본 논문에서는 VWorld에서 제공하는 3차원 공간정보를 이용하여 건물의 높이맵을 포함한 가상환경 데이터 셋을 구축하고, 높이맵과 딥러닝을 이용한 새로운 그림자 탐지 방법을 제안한다. 실험 결과에 의하면, 높이맵을 사용했을 때 기존 방법보다 그림자 탐지 에러율이 감소한 것을 확인할 수 있다.
이제룡,서종태,정재두,이진우,하영주,이정일,곽석준,이중동 한국동물자원과학회 2003 한국축산학회지 Vol.45 No.6
In a trial involving 240pigs, the proximate composition, physico-chemical properites, color, amino acid composition and fatty acid composition of loin muscle were investigated in feeding various finished pig fees. The treatments included feeding control) the low-nutrient density diet(2,960㎈/㎏ ME, 12.25% CP, 0.41% lysine and 0.70% Ca), T1) the medium-nutrient density diet(3,220㎈/㎏ ME, 15.50% CP, 0.87% lysine and 0.90% Ca) and T2) the hight-nutrient density diet(3,350㎈/㎏ ME, 17.50% CP, 1.05% lysine and 0.90% Ca). The crude ash contents of T1 were significantly(p<0.05) higher than those of control and T2. The ?_(u) of T2 were significantly higher than those of control and T1, but cooking loss were significantly(p<0.05) lower than those of control. In compositions amino acid, aspartic acid, threonine, iso-leucine and histidine of T2 were higher than those of control, but proline and glycine were significantly(p<0.05) lower then those of control. The oleic acid(18:1) contents of control were significantly higher than those of T1 and T2, but the contents of linoleic acid(C18:2) and arachidonic(C20:4) acid were significantly(p<0.05) lower. Inconclusion, the results of the experiments suggest that the high-nutrient density diet for pigs tended to improve the postmortem ?_(u) and cooking loss.