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배수진(Sujin Bae,),이여진(Yeojin Lee),이우성(Wooseong Lee),이원준(Wonjun Lee),이제욱(Jeuk Lee),이준형(Joon-Hyung Lee),이지환(Jihwan Lee),인재훈(Jaehun In),임지혜(Jihye Lim),전영미(Yung-Mee Jeon),전채리(Chaery Jeon),한덕현(Doug Hyun Han) 한국중독정신의학회 2017 중독정신의학 Vol.21 No.2
Purpose : Smoking adversely affects the health of smokers and passive smoking threatens the health of people around smokers. The purpose of this review was to summarize the effect of smoking on sleep. Methods : We reviewed 430 articles on smoking and the effect of medication for smoking on sleep. These 430 articles consisted of 78 articles on the physiological effects of nicotine, 20 articles on the effects of nicotine on sleep, 56 articles on smoking related diseases provoking a sleep disorder, 183 articles on other substances (except nicotine) provoking a sleep disorder, and 93 articles on the effects of stopping smoking and medication for stopping smoking on sleep. Results : We summarized the physiological effects of nicotine on sleep, the effects of other substances such as acetaldehyde on sleep, smoking related illnesses including obstructive sleep apnea, chronic obstructive pulmonary disease, chronic rhinosinusitis, cardiovascular and cerebrovascular disease, depression, sleep bruxism, and restless legs syndrome, and the effects of smoking cessation on sleep. Conclusion : Research on the effect of smoking on sleep is necessary to understand the mechanism of smoking. More research on smoking, sleep, and brain mechanisms will give us a closer insight into the relationship between smoking and sleep.
The field application and test of insect pollinators in 5 fruit and vegetable crops
Kyeong Yong Lee,Hee Chul Lee,Somi Lee,Jeonghyeon Lim,Sun-young Lee,Young Uk Park,Young Bo Lee,Heeji Kim,Su-bae Kim,Bosun Park,Sujin Lee,Kyu-Won Kwak,Seong Hyun Min,Dong Hee Lee 한국응용곤충학회 2024 한국응용곤충학회 학술대회논문집 Vol.2024 No.04
국내 원예작물에서 화분매개곤충의 의존도는 해마다 증가하고 있다. 우리는 사과, 딸기 등 화분매개곤충의 의존도가 높은 주요 과수와 시설작물에 대하여 화분매개곤충의 사용기술을 개발하고 이를 현장에 적용하는 연구를 수행하고 있다. 2021년부터 2022년까지 딸기, 키위 등 5가지 주요 농작물에서 화분매개벌을 적용한 결과, 딸기에서 뒤영벌의 적용결과 기존 꿀벌과 통계적으로 같은 수준의 화분매개효과를 나타내었으며, 하우스에서 농약적용시 하우스 밖으로 벌통을 위치시키는 것이 방치보다 벌의 소실을 20% 더 감소시킬 수 있었다. 인공수분 에 의존하고 있는 씨없는 수박에서 수분수 식재와 꿀벌을 이용함으로 기존 벌 방사보다 16% 착과율을 향상시킬 수 있었다. 시설고추에서 꿀벌과 뒤영벌의 혼합사용시 기존 꿀벌 방사보다 고추 수량이 10% 향상되었고, 토마토 에서 660㎡당 뒤영벌의 봉군량을 1.5배 증가시 토마토 수량은 4.4% 향상되었다. 키위는 꿀벌로 기존의 인공수분 을 충분히 대체할 수 있었고, 인건비가 60%이상 절감되었다. 또한 현재 시판중인 30종의 살충제와 27종의 살균제 에 대하여 24시간내 반수치사를 보인 농약은 각각 살충제 6종와 살균제 4종 이었다. 이어서 2023년부터 참외, 멜론, 사과, 단감에 대한 현장적용연구가 진행되고 있다.
Piezoelectric Properties of PMN-PNN-PZT Ceramics and the Simulation of Ultrasonic Cleaner
( Sujin Kang ),( Ju Hyun Yoo ),( Sun A Whang ),( Jae Gyu Lee ),( Jong Hyeon Lee ),( Ji Hoon Lee ),( Dae Yeol Hwang ),( Sua Kim ),( Seong Min Lee ),( Han Byeol Kim ) 한국전기전자재료학회 2023 전기전자재료학회논문지 Vol.36 No.2
In this paper, for the application of ultrasonic cleaners for cleaning dentures and transparent braces, Pb(Mn<sub>1/3</sub>Nb<sub>2/3</sub>)O<sub>3</sub>-Pb(Ni<sub>1/3</sub> Nb<sub>2/3</sub>)O<sub>3</sub>-Pb(Zr,Ti)O<sub>3</sub> [PMN-PNN-PZT] system ceramics were manufactured and their dielectric and piezoelectric properties were investigated. Overall the best properties suitable for the device applications such as ultrasonic cleaner were obtained from the ceramics sintered at 920℃: bulk density of 7.8 g/㎤, the dielectric constant (ε<sub>r</sub>) of 1,689, piezoelectric charge constant (d<sub>33</sub>) of 433 pC/N, planar electromechanical coupling factor (k<sub>p</sub>) of 0.64, mechanical quality factor (Qm) of 835, S<sub>11</sub><sup>E</sup> of 13.37 (10<sup>-12 </sup>N/㎡), and Curie temperature of 315℃ By using the physical properties of this composition, the ultrasonic cleaner was designed and simulated using the commercial ATILA software. For the three-layered ceramics with the dimension of 25 mm × 25 mm × 2.5mm, an excellent displacement of 8.998 ×10<sup>-3</sup> m) and the sound pressure of 147.68 dB were recorded.
CNBP acts as a key transcriptional regulator of sustained expression of interleukin-6
Lee, Eunhye,Lee, Taeyun A.,Kim, Ji Hyun,Park, Areum,Ra, Eun A.,Kang, Sujin,Choi, Hyun jin,Choi, Junhee L.,Huh, Hyunbin D.,Lee, Ji Eun,Lee, Sungwook,Park, Boyoun Oxford University Press 2017 Nucleic acids research Vol.45 No.6
<P><B>Abstract</B></P><P>The transcription of inflammatory genes is an essential step in host defense activation. Here, we show that cellular nucleic acid-binding protein (CNBP) acts as a transcription regulator that is required for activating the innate immune response. We identified specific CNBP-binding motifs present in the promoter region of sustained inflammatory cytokines, thus, directly inducing the expression of target genes. In particular, lipopolysaccharide (LPS) induced <I>cnbp</I> expression through an NF-κB-dependent manner and a positive autoregulatory mechanism, which enables prolonged <I>il-6</I> gene expression. This event depends strictly on LPS-induced CNBP nuclear translocation through phosphorylation-mediated dimerization. Consequently, <I>cnbp</I>-depleted zebrafish are highly susceptible to <I>Shigella flexneri</I> infection <I>in vivo</I>. Collectively, these observations identify CNBP as a key transcriptional regulator required for activating and maintaining the immune response.</P>
Highly selective colorimetric detection of Zn(II) ions using label-free silver nanoparticles
Lee, Sujin,Nam, Yun-Sik,Lee, Ho-Jin,Lee, Yeonhee,Lee, Kang-Bong Elsevier 2016 Sensors and actuators. B Chemical Vol.237 No.-
<P><B>Abstract</B></P> <P>A simple and facile colorimetric method for the detection of zinc ions (Zn<SUP>2+</SUP>) using label-free silver nanoparticles (AgNPs) has been developed. Zn<SUP>2+</SUP> ions induced the aggregation of label-free AgNPs in solution, resulting in a color change from yellow to forest green, which was accompanied by the appearance of a new surface plasmon absorption band at 635nm. The sensitivity of label-free AgNPs towards other metal ions was negligible, with the exception of Fe<SUP>3+</SUP>, which caused a modest interference. The binding site and sensing mechanism for Zn<SUP>2+</SUP> ions in label-free AgNPs were characterized by Fourier Transform infrared spectroscopy, ultraviolet-visible spectroscopy, and transmission electron microscopy. The aggregation of AgNPs in the presence of Zn<SUP>2+</SUP> ions was inhibited by polyvinyl alcohol, which formed a shell on the surface of AgNPs. Furthermore, Zn<SUP>2+</SUP> ions coordinated with BH<SUB>4</SUB> <SUP>−</SUP> on AgNPs through a triangular sixdentate binding structure, thus inducing aggregation of AgNPs in solution.</P> <P>The sensor conditions were optimized with 6.0μM of sodium dodecylbenzenesulfonate (NaDDBS) and 0.23mM AgNPs at pH 6. The absorption ratios (A<SUB>635</SUB>/A<SUB>390</SUB>) of the label-free AgNPs solution exhibited a linear correlation with Zn<SUP>2+</SUP> ion concentration within the range of 0.0−7.6×10<SUP>−6</SUP> molL<SUP>−1</SUP>, with a limit of detection of 0.36×10<SUP>−6</SUP> molL<SUP>−1</SUP>. This cost-effective sensing system allows rapid and facile determination of Zn<SUP>2+</SUP> ions in various types of biological, mineral supplement, and environmental samples.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A facile silver nanoparticle sensor for the visual detection of Zn<SUP>2+</SUP> ion. </LI> <LI> A colorimetric Zn<SUP>2+</SUP> ion sensor using label-free silver nanoparticle. </LI> <LI> This sensor exhibits excellent selectivity for Zn<SUP>2+</SUP> ion over other metal ions. </LI> <LI> This simple sensor can detect ∼0.36×10<SUP>−6</SUP> molL<SUP>−1</SUP> concentration of Zn<SUP>2+</SUP> ion within 15min. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Lee, Yongwon,Lee, Jaegi,Lee, Jeongmin,Kim, Koeun,Cha, Aming,Kang, Sujin,Wi, Taeung,Kang, Seok Ju,Lee, Hyun-Wook,Choi, Nam-Soon American Chemical Society 2018 ACS APPLIED MATERIALS & INTERFACES Vol.10 No.17
<P>Sodium (Na) metal anodes with stable electrochemical cycling have attracted widespread attention because of their highest specific capacity and lowest potential among anode materials for Na batteries. The main challenges associated with Na metal anodes are dendritic formation and the low density of deposited Na during electrochemical plating. Here, we demonstrate a fluoroethylene carbonate (FEC)-based electrolyte with 1 M sodium bis(fluorosulfonyl)imide (NaFSI) salt for the stable and dense deposition of the Na metal during electrochemical cycling. The novel electrolyte combination developed here circumvents the dendritic Na deposition that is one of the primary concerns for battery safety and constructs the uniform ionic interlayer achieving highly reversible Na plating/stripping reactions. The FEC-NaFSI constructs the mechanically strong and ion-permeable interlayer containing NaF and ionic compounds such as Na<SUB>2</SUB>CO<SUB>3</SUB> and sodium alkylcarbonates.</P> [FIG OMISSION]</BR>
( Lee Sujin ),( Lee Haejung ),( Lee Yoonju ),( Park Gaeun ),( Hyun Sookyung ) 부산대학교 간호과학연구소 2022 글로벌 건강과 간호 Vol.12 No.1
Purpose: This study aimed to investigate the predictors of late school-age children’s health behaviors in children and their mothers’ health beliefs, children’s self-esteem, and social support. Methods: A descriptive correlational study was conducted with 152 late school-age children from the 4th to 6th grades and their mothers in Korea. Data were collected from February 19 to March 5, 2020. The collected data were analyzed using t-test, ANOVA, Pearson’s correlation coefficient, and hierarchical multiple linear regression. Results: The average score for health behaviors was 3.35 out of 4.00. The highest subscale of health behavior was mental health, whereas the lowest was eating habits. After adjusting for the influences of the general characteristics of children and their mothers, children’s perceived benefits (β=.17, p=.005), perceived barriers (β=-.20, p=.001), self-efficacy (β=.19, p=.005), and mothers’ perceived severity (β=.18, p=.001) were significant predictors of health behaviors among late school-age children, accounting for 24.0% of the variance (R<sup>2</sup> change=.24, F=11.59, p<.001). The total explanatory power of the final regression model was 72.0% (adjusted R<sup>2</sup>=.72, F=24.98, p<.001). Conclusion: Children’s health beliefs were more important than mothers’ health beliefs in explaining the health behaviors of late school-age children. Nursing interventions should focus on perceived barriers, self-efficacy, and perceived benefits to improve health behaviors of late school-age children.