건진센터 수검자 자료를 이용한 비만지표에 대한 연구

김상만,최희정,이득주,김광민,윤수진 대한비만학회 1997 The Korean journal of obesity Vol.6 No.2

We have examined l5145 persons(7468 men 7677 women) to determine the role of Obesity Index(body mass index, WHR, body fat percent) on the risk of various chronic disease. All the subjects were pooled from Health Examination Center who took the annual health examination from June, 1994 through Jan, 1997, BMI(Body mass index, kg/㎡), WHR(Waist hip ratio) were measured and correlated with the frequency of chronic disease. In order to evaluated the BMI, WHR, Body Fat as an independent factors on rnorbidity, analysis of covariance was applied adjusted for age. The risk of variows chronic diseases were also analyzed with obesity, defined by BMI above 26kg/㎡ (men), 25kg/㎡ (women), by logistic regression adjusted age and sex. Risk of hypertension was 2.6 with 95% eonfidence interval of 1.9-2.8 in obese group. Risk of diabetes mel1itus, hypercholesterolemia, hypertriglyceridemia, gall stone, fatty liver were 3.2(2.3-4.4), 1.2(0.9-1.4), 2.1(1.7-2.8), 1.4(1.1-2.6) and 1.3(0.8-2.3) respectiveiy. The risk of various chronic diseases were also analyzed with obesity, WHR above 0.9(men), 0.81(women), by logistic regression adjusted age and sex. Risk of hypertension was 1.7 with 95% confidence interval of 1.4 -2.1 in obese group. Risk of diabetes mellitus, hypercholesterolemia, hypertriglyceridemia, gall stone, fatty liver were 3.1(2.3-4.0), 1.2(0.9-l.4), 1.4(1.1-2.6), 2.4(l.8-4.8) and 2.1(1.2-4.1) respectively. The BMI, WHR were independent risk factors for various chronic diseases.

전격성 경과를 취한 만성 호산구성 폐렴 환자 1예

윤호상,진춘조,유광하,이상엽,이수인,정상만,김선두,이순제,이길도,전혜정 건국대학교 의과학연구소 2000 건국의과학학술지 Vol.10 No.-

Chronic eosinophilic pneumonia(CEP) is a rare disease of unknown etiology characterized by chronic infiltration of the lung with eosinophils. It presents with profound systemic symptoms comprising fever, night sweats, weight loss, dyspnea and blood eosinophilia with nonsegmental air-space consolidation confined to the outer third of the lung, the "photographic negative of pulmonary edema". Histopathologic features of chronic eosinophilic pneumonia are intraalveolar and interstitial infiltrations with eosinophils, histiocytes, giant cells, scattered lymphocytes and plasma cells. Glucocorticoid therapy cause prompt resolution of symptoms as well as disappearans of blood eosinophils, elevated serum Ig E levels and the roentgenographic lesions. Infrequent radiographic findings include nodular infiltrates, consolidations, cavitations, atelectasis and pleural effusions. Deaths from CEP although rare, have been reported, but the majorities of CEP have benign courses and do not need a therapy with ventilator. We report a case of chronic eosinophilic pneumonia, which had a sudden course associated with diffuse pneumonic consolidations on the both lung and bilateral pleural effusion.

퍼지 검사점을 이용한 주기억 데이타베이스 시스템에서의 회복 기법

이광만 공주영상정보대학 1998 논문집 Vol.5 No.-

본 논문은 주기억 데이타베이스에서 시스템이 파손 시에 발생하는 문제점을 해결하고 최소화하였다. 기존의 시스템들은 디스크에 대한 입출력으로 많은 병목 현상을 나타내고 또한 빠른 회복을 할 수 없었으나, 본 기법은 안정된 로그의 사용으로 디스크에 대한 로그 입출력을 없앴고, 검사점 실행 측면에서도 기존의 퍼지 검사점이 트랜잭션의 일시 정지나 데이타의 일관성을 보장하지 못하는 문제점을 개선한 개선된 퍼지 검사점 기법을 제안하였다.

히터를 내장한 고온 산소센서의 개발(Ⅱ)

이광만,고성택 경북대학교 센서기술연구소 1994 연차보고서 Vol.1994 No.-

반도체 공정기술과 마이크로머시닝 기술을 활용하여 히터가 내장된 고온 산소센서를 개발하였다. 얇은 절연막다이아프램 위에 백금히터와 온도감지기를 내장시켜 0.6와트의 작은 전력으로 약 800℃ 의 온도를 얻었다. 고주파 반응성 스퍼터링법으로 형성된 이트리아로 안정화된 지르코니아(YSZ)박막을 고체전해질로 사용하였다. 제조된 산소센서는 산소함량이 0에서 18몰%의 범위 내에서 전류구동법으로 동작하여 음극영역의 감도는 -3.65㎂/pO_2의 양호한 선형성을 보였으며 2초 이내의 빠른 응답을 보였다. A high temperature oxygen sensor has been developed using micromachining techniques and microelectronic fabrication technology. It is possible to have temperature 800℃ using on-chip platinum heater and temperature detector on the thin insulating diaphragm with applying 0.6 watts. The YSZ thin films as solid electrolyte were deposited by reactive RF suputtering method. The fabricated oxygen sensors have been shown a semi-logarithmic relationship between the oxygen content and current from the measurement within 0 to 18 mol% of the oxygen contents. The sensitivity and response time of the oxygen sensor were -3.65㎂/pO_2 and less than 2 seconds, respectively.

실리콘 미세가공 기술을 이용한 마이크로 진공 센서

이광만,고성택,김영민,고희선 濟州大學校 工科大學 産業技術硏究所 1998 尖端技術硏究所論文集 Vol.9 No.1

A micro-vacuum sensor has been fabricated by using silicon micromachining techniques and platinum thin film. NON insulator was deposited by LPCVD and APCVD methods. The insulator diaphragm was fabricated by silicon anisotropic etching in TMAH solution. Thin film platinum heater and temperature detector were deposited by rf sputtering method and patterning was performed by means of lift-off method. Deposited platinum heater and temperature detector have been shown a linear Ⅰ-Ⅴ characteristics. TCR(temperature coefficient of resistance) of thin film platinum heater and temperature detector was about 0.0042/℃. Fabricated vacuum sensor was measured in the range of 1x10­³Torr to 1×10² Torr, and shows a good linear operating characteristics in the range of 1x10­² Torr에서 1x10˚Torr.

유착성 견관절낭염 환자에서 견갑상신경과 견갑배신경의 병합 차단술의 효과

이삼규,노성만,선광진 대한스포츠의학회 2000 대한스포츠의학회지 Vol.18 No.2

Objective : To investigate the effect of combined nerve block of suprascpular and dorsal scapular nerve as a means of pain management in adhesive capsulitis of shoulder. Method : Of the 55 patients with adhesive capsulitis of shoulder, 30 patients〔age: 62.55(47.2-72-7) years, symptom duration: 60(3-365) days, 12 males and 28 females〕were treated with combined nerve blocks of suprascpular and dorsal scapular nerve as a means of pain management, But, 25 patients〔age : 54.0(25.0-75.0) years, symptom duration: 90(3-730)days, 11 males and 14 females〕were not treated with nerve block. We measured the ROM of flexion and external rotation(˙) as degree via AMA method and VAS(mm). as a degree of shoulder pain weekly. We defined therapeutic duration as above 80% recovery of normal active ROM in flexion and external rotation and below 40mm in VAS. Results : 1) There were significantly decreased VAS from 90mm to 30mm in postnerve block group during serial follow-up exam(p<0.001). 2) There were significantly increased ROM of shoulder flexion from 150˚ to 170˚ in post-nerve block group duing serial follow-up exam (p<0001). 3) There were significantly increased ROM of shoulder external rotation form 40˚ to 60˚ in post-nerve block group during serial follow-up exam(p<0.001). 4) There was significantly increased in exercise compliance(sself-exercise time duration per day) from 60.0 minute to 92.0 minute and decreased in therapeutic duration from 6 weeks to 3 weeks(p<0.001). Conclusion : We concluded that the combined nerve blocks of suprascapular and dorsal scapular nerve were simple, safe, and effective procedure and beneficial to pain relief and shortening of the theraprtic duration of rehabilitative management in patients with adhesive capsulitis of shoulder.

자동차용 센서응용을 위한 CMOS 열전대 공정 개발

이광만,박세광,도양회,Liu, C.C. 경북대학교 센서기술연구소 1996 연차보고서 Vol.1996 No.-

자동차용 센서응용을 위하여 CMOS공정을 이용한 마이크로 열센서의 기초 제조공정을 개발하고 CMOS공정과 호환성을 갖는 열센서의 마스크 설계와 공정 설계를 하였다. LPCVD법, APCVD법 및 실리콘 미세가공기술을 각각 활용하여 열전도율이 낮고 내부응력이 최소화된 NON절연막 다이아프램을 형성하였다. TMAH용액의 농도와 온도를 3∼25wt%와 80∼90℃ 범위내에서 각각 변화시키면서 실리콘의 식각특성을 조사하였다. 그리고 NON절연막의 기계적 및 열적응력을 NON 캔티레버와 빔의 조합으로 이루어진 시험패턴의 식각을 통하여 각각 조사하였다. 그리고 CMOS 구동회로를 내장한 마이크로 열센서의 기초연구를 하였다. A basic fabrication process of micro thermal sensor was developed and the related mask pattern and process were designed by standard CMOS process for the automotive sensor application. An NON dielectric diaphragm with low thermal conductivity and minimum internal stress was fabricated by LPCVD, APCVD methods and silicon micromachining techniques. Etching characteristics of silicon in the TMAH solution was studied with the TMAH concentration and temperature variation of 3∼25wt% and 80∼90℃, respectively. Mechanical and thermal stress of the NON layer were investigated by using a test pattern which composed of cantilever and beam. And a micro thermal sensor with on-chip CMOS driving circuits was studied.

화상을 입은 백서에서 식이의 성분이 세균전위에 미친 영향

이광만,이경근,조지현 圓光大學校 醫科學硏究所 1997 圓光醫科學 Vol.13 No.1-2

Bacterial translocation means the passage of viable bacteria from the gastrointestinal tract to normally sterile tissues such as the mesenteric lymph nodes and other internal organs. It is now clear that translocation is increased in bums and in injury including hemorrhagic shock. Total parenteral nutrition and elemental enteral diets are thought to be associated with atrophy of the intestinal mucosa and increased translocation. The purpose of this study was to determine whether or not the composition of nutrients effects on bacterial translocation in normal and burned rats. 54 male Sprague-Dawley rats were randomized to 3 groups of 18 animals each. Group Ⅰ was non-burned control rats, and group Ⅱ and Ⅲ were burned rats. Rats in group Ⅱ and Ⅲ were subjected to contact dermal bum of 10% and 20% each of their body surface area. All 3 groups were re-randomized to 3 subgroups of 6 animals each; subgroup 1 fed rat chow, subgroup 2 fed elemental diet(Energen®) and subgroup 3 fed oral TPN solution. Animals were fed respective diets ad libitum for 2 weeks, and then mesenteric lymph nodes, portal vein blood, and cecal content were aseptically obtained for culture. Bacterial count in mesenteric lymph nodes(MLN) of burned rats was significantly increased than that of non-burned rats(p=0.033). In burned rats, MLN bacterial count was the highest in the rats fed oral TPN (566.1±870.5/g vs. 270.1±382.4/g in the rats fed elemental diet and 164.9±184.7/g in the rats fed chow). Cecal culture in burned rats revealed a statistically significant increase in the cecal anaerobic count in the rats fed oral TPN when compared to the rats fed chow or elemental diet(p=0.003). There was close correlation between MLN bacterial count and cecal aerobes count(r=0.843, p=0.001). In conclusion, the type of nutrients had influence on bacterial translocation in burned animals partly by increasing the cecal bacterial population.

히터를 내장한 고온 산소센서의 개발

이광만,고성택 경북대학교 센서기술연구소 1993 연차보고서 Vol.1993 No.-

마이크로머시닝 기술과 반도체 공정기술을 활용하여 히터가 내장된 고온 산소센서를 개발하였다. 얇은 실리콘 다이아프램 위에 백금히터와 온도감지기를 내장시켜 작은 전력으로 구동되고 on-site 온도측정이 가능하였다. 약 2와트 부근의 전력에서 약 800℃의 온도를 얻었다. 고주파 반응성 스퍼터링법으로 형성된 이트리아가 약 8몰%가 함유된 지르코니아(YSZ)박막을 고체전해질로 사용하였다 제조된 산소센서는 산소함량이 0에서 18몰%의 범위 내에서 산소함량과 측정전류의 상관관계가 직선적인 응답 특성을 보였다. A high temperature oxygen sensor is developed using micromachining techniques and microelectronic fabrication technology. It is possible to have low power diriving and on-site temperature measurement due to the on-chip platinum heater and temperature detector on the thin silicon diaphragm. The sensor can be operated up to 800℃ and require about two watts power. The YSZ thin films as a solid electrolyte were deposited by reactive suputtering method with the target (8mol% of Y-2O_3 in the ZrO^2). The fabricated oxygen sensors have been shown a linear relationship between the oxygen content and the current from the measurement within 0 to 18 mol% of the oxygen contents.

CVD 다이아몬드 박막의 열전도 특성

이광만,고정대,최치규 濟州大學校 産業技術硏究所 2001 산업기술연구소논문집 Vol.12 No.1

Diamond has outstanding thermal properties that make it the material of choice for heat spreading applications in microelectronic devices. In order to asses thermal properties of diamond films grown by microwave plasma CVD method. we have applied an ac thermal conductivity measurement technique where films are thermally excited at frequency ω while the thermal response is measured at the third harmonic via a lock-in amplifier. This method is insensitive to errors due thermal noise. Before the application to diamond. the measurement technique was tested on fused silica and sapphire. The results were in good agreement with published values. The thermal conductivity of CVD diamond films were measured to be around 3 W/cm·K.