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Distribution of Factors Affecting Foreign Direct Investment in ASEAN Countries
Anh Thi Lan NGUYEN(Anh Thi Lan NGUYEN ),Chau Thi Minh PHAM(Chau Thi Minh PHAM ),Hanh Hong NGUYEN(Hanh Hong NGUYEN ),Dat Ngoc NGUYEN(Dat Ngoc NGUYEN ),Duy Van NGUYEN(Duy Van NGUYEN ) 한국유통과학회 2023 유통과학연구 Vol.21 No.2
Purpose: Research on attracting foreign direct investment plays an important role in ASEAN countries. ASEAN has needed FDI capital for development and integration with many developing countries. Research design, data and methodology: This study is conducted to assess the impact of factors: inflation (INF), economic growth (GDP), population (POP), and trade (TRADE) on attracting foreign direct investment (FDI) of ASEAN countries. The study will find out how factors distribution contributes to FDI attraction. The study collects data from 10 ASEAN countries from 2010 to 2020. With data collected for ten countries from 2010 to 2020, data analysis with panel data will be used in this study. The Regression with Driscoll-Kraay standard errors correction model will be used in the study. Results: Panel data analysis shows that economic growth and population positively impact FDI attraction in ASEAN countries. However, two factors: INF and TRADE, do not affect FDI. Conclusions: Countries need to focus on economic development, create many good conditions for people and domestic enterprises and create opportunities for foreign investors to pay more attention. improving the quality of domestic human resources will help to better improve the working quality factor when the demand for high-quality human resources increases.
Lan, Han-hong,Wang, Cui-mei,Chen, Shuang-shuang,Zheng, Jian-ying The Korean Society of Plant Pathology 2019 Plant Pathology Journal Vol.35 No.5
Interplay between Cymbidium mosaic virus (CymMV)/Odontoglossum ringspot virus (ORSV) and its host plant Phalaenopsis equestris remain largely unknown, which led to deficiency of effective measures to control disease of P. equestris caused by infecting viruses. In this study, for the first time, we characterized viral small interfering RNAs (vsiRNAs) profiles in P. equestris co-infected with CymMV and ORSV through small RNA sequencing technology. CymMV and ORSV small interfering RNAs (siRNAs) demonstrated several general and specific/new characteristics. vsiRNAs, with A/U bias at the first nucleotide, were predominantly 21-nt long and they were derived predominantly (90%) from viral positive-strand RNA. 21-nt siRNA duplexes with 0-nt overhangs were the most abundant 21-nt duplexes, followed by 2-nt overhangs and then 1-nt overhangs 21-nt duplexes in infected P. equestris. Continuous but heterogeneous distribution and secondary structures prediction implied that vsiRNAs originate predominantly by direct Dicer-like enzymes cleavage of imperfect duplexes in the most folded regions of the positive strand of both viruses RNA molecular. Furthermore, we totally predicted 54 target genes by vsiRNAs with psRNATarget server, including disease/stress response-related genes, RNA interference core components, cytoskeleton-related genes, photosynthesis or energy supply related genes. Gene Ontology classification showed that a majority of the predicted targets were related to cellular components and cellular processes and performed a certain function. All target genes were down-regulated with different degree by vsiRNAs as shown by real-time reverse transcription polymerase chain reaction. Taken together, CymMV and ORSV siRNAs played important roles in interplay with P. equestris by down modulating the expression levels of endogenous genes in host plant.
Hong Hye-Lan,Seoung Youl-Hun 한국물리학회 2022 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.81 No.11
The purpose of this study was to compare several quantitative imaging parameters for mobile magnetic resonance imaging (MRI) to stationary MRI. The acquisition conditions for MRI were as follows: the American College of Radiology (ACR) phantom was used as the essential part of MRI quality control (QC) protocols, and seven tests were quantitatively evaluated: geometric accuracy, high-contrast resolution, slice thickness accuracy, slice position accuracy, image intensity uniformity, percent signal ghosting, and low-contrast object detectability. We evaluated image quality using digital analysis methods with the new percent integral uniformity (PIU) method. The results indicate that the mobile MRI was degraded with signifcant diferences in geometric accuracy (p=0.021), image intensity uniformity (PIU p=0.248, New PIU p=0.043), and high-contrast spatial resolution of 0.9 mm (p=0.019). In particular, image intensity uniformity was signifcantly diferent between the two diferent MRI system based on the new PIU (p=0.043), but was not on the conventional PIU (p=0.248). Our methods suggest that mobile MRI is more easily exposed to external high-frequency noise than stationary MRI. In conclusion, when reading images with mobile MRI, it is important to pay attention to geometric accuracy and high-contrast resolution, which require shielding against external high-frequency signals.
Lan Hong,Guo-Hua Gong,Li Yu,Ming-Xia Song,Xun Cui,Zhe-Shan Quan 대한약학회 2013 Archives of Pharmacal Research Vol.36 No.11
A series of 7-alkoxy-4,5-dihydro-[1,2,4]oxadiazolo[4,3-a]quinolin-1-ones was synthesized and theirnegative inotropic effects were evaluated by measuring theleft atrium stroke volume in isolated rabbit heart preparations. All compounds moderated the cardiac workload bydecreasing heart rate and contractility (inotropic effects). Among them, compound 6 was found to be best potent witha -28.89 ± 1.91 % decrease in the stroke volume at aconcentration of 3 9 10-5 M in our in vitro study.
Transcriptome Analysis of Long-Term Exposure to Blue Light in Retinal Pigment Epithelial Cells
( Hong Lan Jin ),( Kwang Won Jeong ) 한국응용약물학회 2022 Biomolecules & Therapeutics(구 응용약물학회지) Vol.30 No.3
Dry age-related macular degeneration (AMD) is a type of progressive blindness that is primarily due to dysfunction and the loss of retinal pigment epithelium (RPE). The accumulation of N-retinylidene-N-retinylethanolamine (A2E), a by-product of the visual cycle, causes RPE and photoreceptor degeneration that impairs vision. Genes associated with dry AMD have been identified using a blue light model of A2E accumulation in the retinal pigment epithelium and transcriptomic studies of retinal tissue from patients with AMD. However, dry macular degeneration progresses slowly, and current approaches cannot reveal changes in gene transcription according to stages of AMD progression. Thus, they are limited in terms of identifying genes responsible for pathogenesis. Here, we created a model of long-term exposure to identify temporally-dependent changes in gene expression induced in human retinal pigment epithelial cells (ARPE-19) exposed to blue light and a non-cytotoxic dose of A2E for 120 days. We identified stage-specific genes at 40, 100, and 120 days, respectively. The expression of genes corresponding to epithelial-mesenchymal transition (EMT) during the early stage, glycolysis and angiogenesis during the middle stage, and apoptosis and inflammation pathways during the late stage was significantly altered by A2E and blue light. Changes in the expression of genes at the late stages of the EMT were similar to those found in human eyes with late-stage AMD. Our results provide further insight into the pathogenesis of dry AMD induced by blue light and a novel model in vitro with which relevant genes can be identified in the future.
A Simple Nanocomposite Coating Process for Titanium Metal Surfaces Using a Polyborazine Precursor
Hong, Lan-Young,Kim, Dong-Jin,Kim, Dong-Pyo 한국공업화학회 2004 Journal of Industrial and Engineering Chemistry Vol.10 No.6
A Ti-based nanocomposite coating layer was produced by simple dip-coating of low-viscosity polyborazine, -[B₃N₃H,]_x-, onto a bare Ti substrate surface, followed by pyrolysis at up to 1400℃ under an inert atmosphere. When annealed at higher temperatures, the Ti surface layer showed a step-wise change to form a nanocomposite phase composed of TiO₂, TiN, and TiNyOz, starting from the formation of TiO₂at 800℃ as a result of the presence of native oxygen. The hardness of the modified surface increased to 304 Hv from 132 Hv for the bare sample. The formation mechanism was studied using XRD, SEM, AES, and ESCA instruments. These preliminary results prove that the efficient nanocomposite coating process using preceramic polymers is a promising route for producing designed compositions on metal bodies for various industrial applications.
Hong, Lan-Young,Ryu, So-Hyoung,Kim, Dong-Pyo American Scientific Publishers 2010 Journal of Nanoscience and Nanotechnology Vol.10 No.10
<P>The microcellular SiCN ceramics with high porosity and high surface area were fabricated from polysilazane as a viscous SiCN ceramic precursor and expandable microspheres as a self-sacrificial template. The fabrication steps were composed of (1) forming of expandable microsphere compact, (2) infiltrating polysilazane into the compact, (3) foaming and curing, (4) pyrolysis in N2 gas. The microcellular structures and properties of the obtained ceramic products depended on the foaming and curing conditions as well as the pyrolysis temperature. When foamed and cured at 120 degrees C for 30 min, then pyrolyzed at 1000 degrees C in N2, the microcellular product exhibited the largest cell size 9.3 microm with the lowest cell densities 2.2 x 108 cells/cm2, 93% of porosity and surface area of 356 m2/g. Furthermore, the higher temperature pyrolysis at 1300 degrees C induced significant change in the microcellular morphology by reducing the cell size with thicker wall and the cell density. Finally, it demonstrated an efficient way of manufacturing highly porous microcellular ceramics with no etching process using a polyvinylsilazane and expandable microspheres for catalytic supporting application.</P>