제왕절개 분만율의 지역간 변이와 관련요인에 대한 연구

김혜경,이정운,박강원,문옥륜,Kim, Hye-Kyung,Lee, Jeon-Un,Park, Kang-Won,Moon, Ok-Ryun 대한예방의학회 1992 Journal of Preventive Medicine and Public Health Vol.25 No.3

The purpose of this study is to estimate cesarean section rate in Korea and analyze the socioeconomic variables and health resources which affect regional variation in the rate. Samples were drawn from the record of vaginal and cesarean section deliveries based upon insurance claim bills which have been submitted to the National Federation of Medical Insurance for the first three months, January through March, 1991. The results are obtained as follows : It was found that. cesarean section rate was increasing rapidly up to 23.1% in 1991. Cesarean section per 10 thousand insured people was 4.8 and the number of cesarean section per 10 thousand insured eligible($15{\sim}49$ years old) female was 7.6. The fee for normal delivery was 109,489 won and that for cesarean section was 390,024 won. The average days of hospitalization in normal delivery was 2.3 days, and those in cesarean section was 7.6 days. On the average cesarean section has a longer of stay as much as by 4.3 days and cost 3.6 times more than normal deliveries. Cesarean section rates vary among medical facilities 19.8% at clinics 37.6% in small-scale hospitals, and 29.1% in general hospitals. The regional variation of cesarean section rates was also fairly prominent. The South Cheju Gun has the highest rate of cesarean section, 56.2%. Meanwhile no cesarean section cases has been reported in Sunchang Gun during the period of this study. The variation is noted among provinces. The rate for Cheju province has been 3.4 times higher than that for Chunnam. The number of cesarean section per 10 thousand insured people vary greatly among regions, too. This study has found that there exists significant regional variations among various geographic units in terms of average length of stay, average cost, number of obsretricians and number of beds. Multiple regression analysis was done to identify factors explaining the regional variance of various cesarean section rates : In the urban areas, no significant explaining variables were noted except the number of beds for the dependent variable of cesarean section cases per 10 thousand insured eligible females. The smaller the number of bed, the more cases of cesarean section was noted for an urban area. The is mostly because the rate of cesarean section is higher in medium-size hospitals than in large general hospitals. In the rural areas, the factor of education has been found significant for all three deplendent variables. The higher the educational level, the rate of cesarean section is most likely to rise. An income variable measured by the amount of monthly insurance contribution has been identified a powerful predictor in explaining the valiance of cesarean section rates. The same has been noted for the number of obstetricians. Similar findings are observed for the country as a whole. The income level has veen found as the most powerful explaining factor in the regional variance of cesarean section rates. In general the rate is higher in the urban areas, and lower in the area with more small hospitals. As this is the initial attempt to identify the factors relevant to the regional difference in the rates of cesarean section, more elaborated study is urgently required.

Short Communications : Development of T-cell Based Reporter Assay System to Identify Immunomodulators from Herbal Medicine

Won Kyung Jeon,Ji Sun Hwang,Ho Keun Kwon,Chung Gu Lee,Sin Hyeog Im,Byoung Seob Ko 한국응용생명화학회 2009 Applied Biological Chemistry (Appl Biol Chem) Vol.52 No.6

To evaluate immunomodulators from herbal medicines that affect the expression of IL-10 and TNF-α, we developed a cell-based high throughput screening system and tested 17 kinds of herbal medicine. We found that extracts of Coptidis Rhizoma can be used to s

Comparison of Micronutrient Levels between Oral Feeding and Enteral Feeding in Chronic Stroke Patients

Kyung Soo Jeon,Hee Seung Yang,Hea-Eun Yang,Ah Rom Song,Ji Won Kwon 대한연하장애학회 2019 대한연하장애학회지 Vol.9 No.1

Objective: This study aimed to investigate the difference in micronutrient levels between oral feeding and enteralfeeding in chronic stroke patients to assess the risks of enteral feeding. Methods: Patients with chronic stroke who were admitted to the Department of Rehabilitation Medicine betweenJanuary 2011 and June 2012 were enrolled. The serum concentrations of iron, copper, zinc, folate, and vitamin B12,as well as the absolute CD4 and CD8 lymphocyte counts, were assessed. Results: Of the 73 patients enrolled in this study, 50 were fed orally, while the other 23 were fed through a percutaneousendoscopic gastrostomy (PEG) or nasogastric (NG) tube. The serum concentrations of vitamin B12 and folatewere significantly higher in the enteral feeding group than in the oral feeding group. However, the serum concentrationof zinc was significantly lower in the enteral feeding group. Conclusion: There is little difference between enteral feeding and oral feeding in terms of micronutrient provisionexcept that the serum concentration of zinc in the enteral feeding group was significantly lower than that in the oralfeeding group. Clinicians should recognize that chronic stroke patients who require tube feeding have a risk ofmicronutrient deficiency. Early detection of malnutrition and micronutrient deficiency is important for providing thenecessary nutrients.

Role of Dedicated Subspecialized Radiologists in Multidisciplinary Team Discussions on Lower Gastrointestinal Tract Cancers

Jeon Sun Kyung,Kim Se Hyung,Shin Cheong-Il,Yoo Jeongin,Park Kyu Joo,Ryoo Seung-Bum,Park Ji Won,Kim Tae-You,Han Sae-Won,Lee Dae-Won,Chie Eui Kyu,Kang Hyun-Cheol 대한영상의학회 2022 Korean Journal of Radiology Vol.23 No.7

Objective: To determine the impact of dedicated subspecialized radiologists in multidisciplinary team (MDT) discussions on the management of lower gastrointestinal (GI) tract malignancies. Materials and Methods: We retrospectively analyzed the data of 244 patients (mean age ± standard deviation, 61.7 ± 11.9 years) referred to MDT discussions 249 times (i.e., 249 cases, as five patients were discussed twice for different issues) for lower GI tract malignancy including colorectal cancer, small bowel cancer, GI stromal tumor, and GI neuroendocrine tumor between April 2018 and June 2021 in a prospective database. Before the MDT discussions, dedicated GI radiologists reviewed all imaging studies again besides routine clinical reading. The referring clinician’s initial diagnosis, initial treatment plan, change in radiologic interpretation compared with the initial radiology report, and the MDT’s consensus recommendations for treatment were collected and compared. Factors associated with changes in treatment plans and the implementation of MDT decisions were analyzed. Results: Of the 249 cases, radiologic interpretation was changed in 73 cases (29.3%) after a review by dedicated GI radiologists, with 78.1% (57/73) resulting in changes in the treatment plan. The treatment plan was changed in 92 cases (36.9%), and the rate of change in the treatment plan was significantly higher in cases with changes in radiologic interpretation than in those without (78.1% [57/73] vs. 19.9% [35/176], p < 0.001). Follow-up records of patients showed that 91.2% (227/249) of MDT recommendations for treatment were implemented. Multiple logistic regression analysis revealed that the nonsurgical approach (vs. surgical approach) decided through MDT discussion was a significant factor for patients being managed differently than the MDT recommendations (odds ratio, 4.48; p = 0.017). Conclusion: MDT discussion involving additional review of radiology examinations by dedicated GI radiologists resulted in a change in the treatment plan in 36.9% of cases. Changes in treatment plans were significantly associated with changes in radiologic interpretation.

Characteristics of cephalosporin-resistant Salmonella isolates from poultry in Korea, 2010-2017

Jeon, Hye Young,Kim, Yeong Bin,Lim, Suk-Kyung,Lee, Young Ju,Seo, Kwang Won Elsevier 2019 Poultry science Vol.98 No.2

A Trend of Yin-tonifying Formulas Compared with Yang-tonifying Formulas on Anti-platelet and Anti-thrombotic Activity

Jeon, Won-Kyung,Yoo, Bo-Kyung,Ahn, Sang-Young,Lee, Ju-Hyun,Ahn, Sang-Woo,Ko, Byoung-Seob The Society of Korean Medicine 2009 대한한의학회지 Vol.30 No.6

Objectives: Formulas for treatment of yin or yang deficiency conditions have been commonly used in traditional Korean medicine. The aim of this study is to examine the possible inhibitory effects of yin- or yang-tonifying formulas on in vivo anti-platelet activity and in vivo anti-thrombotic activity. Methods: We tested the effects of 26 types of yin- or yang-tonifying formulas on platelet aggregation induced by collagen in human whole blood using the impedance method of aggregometry and accessed a biomarker of platelet activation using thromboxane $B_2$ immunoassay. We also tested the anti-thrombotic effects of effective candidates on experimental models of thrombosis in mice. Results: 3 types of yin-tonifying formulas and 3 types of yin-yang-tonifying formulas were selected to be the most effective candidates (p<0.01). Also, through in vivo study, the antithrombotic activities of Igyeong-tang, Gamisipjeondaebo-tang, and Gamisoyo-san-treated groups, with recovery rate of 60, 50, and 45.45%, respectively, were observed to be higher than those of the control group (saline, 36.8%) in mouse acute thrombosis. Conclusion: These results show that yin-tonifying formulas are more effective in anti-platelet and anti-thrombotic activity than yang-tonifying formulas.

Effect of calcination temperature on the association between free NiO species and catalytic activity of Ni−Ce_0.6Zr_0.4O₂ deoxygenation catalysts for biodiesel production

Jeon, Kyung-Won,Shim, Jae-Oh,Jang, Won-Jun,Lee, Da-We,Na, Hyun-Suk,Kim, Hak-Min,Lee, Yeol-Lim,Yoo, Seong-Yeun,Roh, Hyun-Seog,Jeon, Byong-Hun,Bae, Jong Wook,Ko, Chang Hyun Elsevier 2019 RENEWABLE ENERGY Vol.131 No.-

<P><B>Abstract</B></P> <P>In this study, a series of Ni−Ce<SUB>0.6</SUB>Zr<SUB>0.4</SUB>O<SUB>2</SUB> catalysts, which were synthesized by co-precipitation followed by calcination at different temperatures, were applied for the deoxygenation of oleic acid. The physicochemical properties of the catalysts were characterized by N<SUB>2</SUB> adsorption-desorption, X-ray diffraction (XRD), H<SUB>2</SUB> chemisorption, H<SUB>2</SUB> temperature-programmed reduction (H<SUB>2</SUB>-TPR), NH<SUB>3</SUB> temperature-programmed desorption (NH<SUB>3</SUB>-TPD), and X-ray photoelectron spectroscopy (XPS). The Ni−Ce<SUB>0.6</SUB>Zr<SUB>0.4</SUB>O<SUB>2</SUB> catalyst calcined at 300 °C exhibited the highest conversion for oleic acid as well as selectivity for diesel-range compounds. It is predominantly related to the highest amount of free NiO species. In addition, the acidity of the catalyst significantly affected the selectivity and distribution of products.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Calcination temperature influences the physicochemical properties of Ni–CZO. </LI> <LI> The Ni–CZO calcined at 300 °C exhibited the highest catalytic performance. </LI> <LI> Catalyst acidity significantly affected the selectivity and products distribution. </LI> <LI> Hence, the Ni–CZO is a promising for producing diesel-like hydrocarbons via DO. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Development of T-cell Based Reporter Assay System to Identify Immunomodulators from Herbal Medicine

Jeon, Won-Kyung,Hwang, Ji-Sun,Kwon, Ho-Keun,Lee, Chung-Gu,Im, Sin-Hyeog,Ko, Byoung-Seob The Korean Society for Applied Biological Chemistr 2009 Applied Biological Chemistry (Appl Biol Chem) Vol.52 No.6

To evaluate immunomodulators from herbal medicines that affect the expression of IL-10 and TNF-${\alpha}$, we developed a cell-based high throughput screening system and tested 17 kinds of herbal medicine. We found that extracts of Coptidis Rhizoma can be used to stimulate TNF-${\alpha}$ and IL-10 expression.

Isolation of a Calcium-binding Substance from Anchovy

Jeon, So-Jeong,Kim, Won-Gon,Song, Kyung-Bin The Korean Society for Applied Biological Chemistr 2010 Applied Biological Chemistry (Appl Biol Chem) Vol.53 No.4

Dried anchovy (Engraulis japonica) was extracted using hot water and filtered with a YM-3 membrane to isolate a calcium binding substance. The membrane filtered solution was fractionated using gel permeation chromatography, ion exchange chromatography, reverse-phase high performance liquid chromatography, and fast protein liquid chromatography to detect calcium-binding substances. The isolated substance was identified as adenosine by nuclear magnetic resonance spectroscopy.

Catalytic deoxygenation of oleic acid over a Ni-CeZrO₂ catalyst

Jeon, Kyung-Won,Na, Hyun-Suk,Lee, Yeol-Lim,Ahn, Seon-Yong,Kim, Kyoung-Jin,Shim, Jae-Oh,Jang, Won-Jun,Jeong, Dae-Woon,Nah, In Wook,Roh, Hyun-Seog Elsevier Ltd 2019 Fuel Vol.258 No.-

<P><B>Abstract</B></P> <P>Ni-loaded Ce<SUB>0.6</SUB>Zr<SUB>0.4</SUB>O<SUB>2</SUB> catalysts were prepared by a co-precipitation method and subsequently employed in the deoxygenation of oleic acid under solvent-free conditions. Among the prepared catalysts, the 20 wt% Ni-Ce<SUB>0.6</SUB>Zr<SUB>0.4</SUB>O<SUB>2</SUB> catalyst exhibited the highest catalytic activity, i.e., 98.3% oleic acid conversion, with 33.9% C<SUB>9</SUB>-C<SUB>17</SUB> selectivity, and a 95.7% oxygen removal rate. The basic fuel properties of the obtained products were then examined to determine their potential for use in a diesel engine. The product produced using the 20 wt% Ni-Ce<SUB>0.6</SUB>Zr<SUB>0.4</SUB>O<SUB>2</SUB> catalyst exhibited a particularly high calorific value (i.e., 10213 cal/g, similar to that of commercial diesel, i.e., 10220 cal/g), the lowest viscosity (25.2cP), and the lowest solidification temperature (−15 °C).</P> <P><B>Highlights</B></P> <P> <UL> <LI> Biofuel was produced by deoxygenation of oleic acid over Ni-Ce<SUB>0.6</SUB>Zr<SUB>0.4</SUB>O<SUB>2.</SUB> </LI> <LI> The Ni-loaded Ce<SUB>0.6</SUB>Zr<SUB>0.4</SUB>O<SUB>2</SUB> catalyst containing 20 wt% Ni loading was optimal. </LI> <LI> 20 wt% Ni-Ce<SUB>0.6</SUB>Zr<SUB>0.4</SUB>O<SUB>2</SUB> exhibited 98.3% conversion and 33.9% selectivity. </LI> <LI> Furthermore, this catalyst showed a superior oxygen removal rate (95.7%). </LI> <LI> The biofuel produced via this catalyst showed a high calorific value (10213 cal/g). </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>