오렌지로부터 아플라톡신B₁의 정량분석에 관한 연구

장향동,백광균,구경림,옥선미,최진석,고은주,류성렬 한국공업화학회 2004 응용화학 Vol.8 No.2

Aflatoxin B₁ was known to have the strongest poisonous character among Aflatoxin compounds. To search the production of Aflatoxin B1 according to the change of temperature, relative humidity and incubation days, orange incubated with Aspergillus parasiticus KCCM 35078 was incubated at 20℃, 25℃, 30℃ at relative humidity 60%, 70%, 80% and for incubation time 3, 4, 5, 6, 7 days.. Production of Aflatoxin B₁ shows that the highest production appeared at 25℃ and its relative humidity 70%. The result that was quantitatively analyzed by using HPLC was 77.41ppm, and by using Fluoroscence detector was 87.87ppm. - Production of Aflatoxin B₁ shows that the lowest production appreared at 20℃ and its relative humidity 80%(HPLC), 60%(Fluoroscence detector). The result that was quantitatively analyzed by using HPLC was 4.47ppm, and by using Fluoroscence detector was 4.17ppm. The structure of Aflatoxin B₁ was identify with authentic sample by using instrumental analysis methods of GC/MS, ¹H-NMR, FT-IR respectively.

적외선을 이용한 액체 유기물 내 수분 농도 감지기

장성태,정종대,정경석 한국기술교육대학교 2004 論文集 Vol.10 No.2

Water in liquid organic chemicals tends to lower power output or result in the failure of internal combustion engines. There have been lots of proved standard techniques of measuring the water contents in oil, such as distillation, coulometric Karl Fischer titration, and centrifuge. These techniques, however, are mainly for laboratory uses and hard to be used for the continuous monitoring application. Light absorption of water in the near-IR has been used to develop a sensor system to continuously detect water presence in the oil flow. Result shows functional correspondence in the output voltage of the sensor system and water concentration.

정상인 및 신기능장애환자에서 Carumonam(AMA-1080)의 약동학

임동석,이경훈,엄재호,한진석,김성권,장인진,신상구 大韓臨床藥理學會 1994 臨床藥理學會誌 Vol.2 No.1

중소도시에 거주하고 있는 영유아의 건강상태 고찰 : 유치원, 어린이집을 중심으로

장경옥 ; 손재석 김천대학교 2012 김천대학교 논문집 Vol.32 No.-

The purpose of this research is to assess and understand the health conditions and lifestyle patterns of babies and toddlers who attend preschool and childcare centers in small and mid-sized cities, and provide structure and criteria for implementing the fundamental elements for early childhood education and development. A sample population focused on those attending preschools and child care centers in the Gimcheon area were assessed on June 20 through July 5, 2011 by means of questionaires. These children's health results were found to be higher than the national standard for normal 3, 4 and 5 year old children's health development. Findings also showed there was no difference in the level of partic-ipation in health fitness programs among mothers who held different vocations. This research showed that more children were going to childcare centers per year, which came out to be about 12.77 times more than preschool, which had a slightly lower number of 11.81 times. A slighter higher number of the children attending preschool had mothers who were stay-at-home moms (precisely 12.23 times more) as opposed to those whose mothers worked (11.19 times). Lastly, results showed that the children of mothers who did not work had a higher percentage of eating breakfast rather than those children whose mothers worked.

Nortriptyline 청소율과 Metoprolol 산화대사능과의 상관관계

정원석,장인진,이경훈,신상구,우종인,박찬웅 大韓臨床藥理學會 1993 臨床藥理學會誌 Vol.1 No.2

3D 온라인 슈팅 게임 개발 : "3D 포트리스"

金敬植,崔勝寬,寓昔珍,申一卿,朴勝浩,李東熙,李東建,張孝善 호서대학교 공업기술연구소 2000 工業技術硏究所論文集 Vol.19 No.-

In this paper, features and efficiencies of the 3D engine are described which has been developed through the research of 3D real time rendering techniques. And an on-line shooting game "3D Fortress" which has been developed using this 3D engine with server technologies is introduced for the techniques and methodology applied in the process of development of the game as well as the features and discussions of its implementation.

정신간호조무사 양성소 교육과정 전후의 정신질환에 대한 태도조사

최석민,장경준 大韓神經精神醫學會 1996 신경정신의학 Vol.35 No.5

이 연구는 정신질환에 대한 태도 변화가 적절한 교육에 의하여 변화할 수 있다는 관점에서, 정신질환자 치료에 일익을 담당하게 정신간호조무사를 양성하는 국립서울정신병원 부설 정신 간호조무사 양성소의 학생을 대상으로 정신질환에 대한 태도 조사를 하여, 정신과 교육이 정신질환에 대한 태도에 미치는 영향을 보았다, 연구 방법은 1993년과 1994년에 양성소 교육을 받고 전과정을 수료한 39명을 대상으로, 정신질환에 대한 태도를 묻는 설문지를 사용하여 정신과 교육전, 후의 정신질환에 대한 태도의 변화를 보았으며, 그 결과는 다음과 같다. 먼저 양성소 교육이 정신질한에 대한 태도에 미친 영향을 보면 다음과 같다. 1) 정신병 환자에 대한 개념 및 태도는 긍정적인 방향으로 변하였다(p<0.05). 2) 정신병원에 입원한 환자에 대한 치료 전망, 개방병동에 대한 태도의 변화는 부정적인 방향으로 변화하였다(p<0.05). 3) 나머지 신경증에 대한 개념, 정신질환에 대한 부정적 편견, 정신질환의 치료 예후에 대한 태도, 입원치료와 가정내 보호에 대한 태도, 정신병동의 기능에 대한 태도는 통계적으로 유의한 수준의 변화가 없었다. 이 연구의 조사 대상군의 특성을 알아보기 위해 동일한 설문을 사용하여 조사한 일반인 군, 의과 대학생 군과 비교해 보면 다음과 같은 결과를 얻었다. 1) 이 연구의 교육전 대상군은 정신과 실습을 받지 않은 의과대학생군과 정신질환에 대한 태도를 묻는전체 문항에서 통계적으로 유의한 차이를 보이지 않았다. 2) 이 연구의 교육적 대상군은 일반인보다 신경증에 대한 개념, 정신질환의 치료 예후에 대한 태도, 정신병원에 입원되어 있는 환자의 치료전망에 대한 태도를 묻는 문항에서 일반인보다 부정적으로 대답하였다. Objective : This study was designed to evaluate the effect of the psychiatric nursing assistant education done at Seoul National Psychiatric Assistant School on the attitude toward mental illness. Methods : The subjects were 39 graduates from Seoul National Psychiatric Assistant School, during 1993- 1994. They were assessed during pre- and post-education periods with Scale for Mental Health Attitude(Star 1952). Chi-square test was used for statistical analysis. Results : 1) Statistically significant changes were shown in concepts and attitudes toward mentally ill patients, therapeutic prospect to inpatient, and attitude toward open ward (p<0.05). 2) Statistically significant changes were not shown in concepts of neurosis, negativistic bias toward mental illness, therapeutic prognosis of mental illness, attitude toward inpatient treatment and care in home, and attitude toward function of psychiatric ward. Conclusion : We conclude that psychiatric nursing assistant education needs further improvement.

Pastry 마가린 함량과 적층 수에 따른 puff pastry 제조 특성

한장호,김석영,윤여창,이시경 한국응용생명화학회 2003 Applied Biological Chemistry (Appl Biol Chem) Vol.46 No.4

Puff pastry의 제조 공정에서 pastry 마가린 함량과 적층 수의 변화가 제품의 수분 함량, 굽기 손실, 부피, vapor action 등에 미치는 영향을 조사하였다. Pastry 마가린 함량이 90%로 동일하고 적층 수가 27결일 경우 10.8±0.6%의 수분 함량을 나타냈으며, 1024결일 경우 16.7±0.3%로 적층 수가 증가할수록 제품의 수분함량은 증가 하는 경향을 보였다. 적층 수를 256결로 동일하게 하고, pastry 마가린 함량이 50%일 경우는 17.3±0.5%로 나타났으며, 130%에서는 7.5±0.2%로 pastry 마가린 함량이 증가할수록 제품의 수분 함량은 감소하였다. Pastry 마가린 함량을 70%로 동일하게 했을 때 굽기 손실의 변화는 27결일 경우 25.0±0.7%로 나타났으며, 1024결일경우엔 18.8±0.6^로 나타나 적층 수가 증가할수록 제품의 굽기 손실은 감소하는 경향을 보였다. 적층 수를 27결로 동일하게 한 경우에서는 pastry 마가린 함량이 90%일 때 25.4±0.4%의 굽기 손실이 발생하였으며, 110%에서 26.9±0.4%로 굽기 손실이 가장 높게 나타났다. Pastry 마가린 함량이 130%이고 적층수가 81결일 때에 21.87±0.79㎖/g로 최대의 부피를 나타내었다. 또한 vapor action의 크기는 9.15㎜가 pastry 마가린 함량 110%, 적층 수 256결에서 8.25±0.50개로 가장 많이 나타났다. This study was carried out to investigate the effect of pastry margarine content and number of layers on moisture content, baking loss. specific loaf volume and the vapor action in the manufacturing process of puff pastry. As the number of layers of the puff pastry increased the moisture content of the products slightly increased. And the moisture contents of the products decreased, as the pastry margarine contents of the puff pastry increased in the same number of layers. The baking loss of the products tended to decrease as the number of layers increased. On the other hand, as the pastry margarine contents of the puff pastry increased, the baking loss of the product increased. When the pastry margarine content in puff pastries became 130%, 81 layers provided the maximum specific loaf volumes 21.62±0.79 ㎖/g of puff pastries. When 110% of margarine and 256 layers were applied for preparation of puff pastry, the number of vapor action was 8.25±0.50 with the vapor action size of 9-15 ㎜.

Prevotella nigrescens의 용혈특성에 관한 연구

곽주석,장훈상,장석우,이수종,유용욱,민경산 大韓齒科保存學會 2005 Restorative Dentistry & Endodontics Vol.30 No.4

세균의 용혈활성은 세균이 숙주 내에서 생존하기 위해 필요한 철을 획득하기위한 특성이며 기능면에서 볼 때 숙주에 대한 중요한 독력인자로 간주될 수 있다. 본 연구에서는 괴사치수 및 치근단 치주염으로 진단된 환자의 근관에서 분리한 Prevotella nigrescens의 용혈활성을 다양한 조건 하에서 측정하여 그 특성을 규명하는 것을 목적으로 한다. 1. 임상에서 분리한 P. nigrescers와 표준균주인 P. nigrescers ATCC 33563에서 모두 용혈활성이 나타났다. 2. 사람, 면양 및 말 세 가지 종에 대해 용혈활성을 비교한 결과 사람의 적혈구에서 가장 강한 용혈활성을 나타내었다. 3. 용혈소 억제제인 NaN₃와 dithiothreitol (DTT)는 농도의존적으로 P.nigrescers의 용혈활성을 감소시켰다 (p<0.05). 4. P. nigrescers가 최대 용혈활성을 나타내는 최적의 pH는 4이었으며, 50℃이하의 온도에서는 용혈활성을 보였으나 95℃에서 급격히 감소하였다. 5.배양조건에 따른 P. nigrescens의 용혈활성을비교한 결과 10% CO₂배양기에 배양한 경우혐기성 조건에서 배양한 것보다 더 높은 용혈활성을 보였다. Hemolytic property is a specific feature of bacteria to obtain iron which is essential for its survival in host tissues. Therefore, it is thought to be one of several factors of virulence. The purpose of this study was to investigate the hemolytic properties of Prevotella nigrescens isolated from the teeth diagnosed as pulp necrosis and apical periodontitis under the presence of hemolysin inhibitors such as NaN3 and dithiothreitol, heat, various pH and cultural conditions. The results were as follows; 1. Clinically isolated P. nigrescens strains and standard P. nigrscens ATCC 33563 showed hemolytic activity. 2. P. nigrescens showed higher hemolytic activity against human erythrocytes than sheep or horse erythrocytes. 3. NaN₃ and dithiothreitol (DTT) reduced the hemolytic activity of P. nigrescens in a dose dependent manner (p<0.05). 4. Optimal pH for the maximum hemolytic activity of P. nigrescens was 4.0 and the hemolysin was stable under the 50℃, but the hemolytic activity was significantly decreased at 95℃. 5. P. nigrescens cultured in 10% CO₂ condition showed higher hemolytic activity than the bacteria cultured in the anaerobic condition.[J Kor Acad Cons Dent 30(4):335-343,2005]

부인과질환, 월경통과 여성 체형 및 체온의 상관성 연구

최석영 ( Seok Young Choi ),안지윤 ( Ji Yoon Ahn ),이미주 ( Mi Joo Lee ),이진무 ( Jin Moo Lee ),장준복 ( Jun Bock Jang ),이경섭 ( Kyung Sub Lee ),이창훈 ( Chang Hoon Lee ) 대한한방부인과학회 2012 大韓韓方婦人科學會誌 Vol.25 No.4

Objectives: A women`s body type or body temperature is often thought to be associated with gynecologic disorders or dysmenorrhea. The purpose of this study is to analyse the characteristics of body type and body temperature in relation to gynecologic disorders and dysmenorrhea. Methods: We studied 40 patients visiting Kangnam Kyung-hee Medical Center from Jan. 1st, 2010 to March 31st, 2012. Body type and body temperature were compared between Gynecologic disorder group and non-Gynecologic disorder group. Body type and body temperature were compared again between Dysmenorrhea group and non-Dysmenorrhea group. SPSS 18.0 for Windows was used to analyse the data. Results: There was no statistically significance difference in body type and body temperature between Gynecologic disorder group and non-Gynecologic disorder group. Dysmenorrhea group had more developed lower body and greater temperature difference between lower abdomen and foot compared to non-Dysmenorrhea group. Conclusions: The results suggest that women with developed lower body and greater temperature difference between abdomen and lower extremity are more prone to dysmenorrhea.