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      • KCI등재

        GIS기반 동남 광역권 산업체 정보시스템 구축 및 활용

        남광우 ( Kwang Woo Nam ),권일화 ( Il Hwa Kwon ),박준호 ( Jun Ho Park ) 한국지리정보학회 2014 한국지리정보학회지 Vol.17 No.1

        Following the technology developments of traffic network and communication for the wide area, the importance of the cooperation system to vitalize the wide area economy is increasing. Therefore, in this study, DongNam Kwon industry information system is established for the industrial information sharing based on GIS in the DongNam Kwon wide area economy. The DongNam Kwon is an industrial integration area centered with the manufacturing so that the operation of effective industrial cluster and cooperation systems are required across the administrational boundaries. To establish the database of the information, the information system was established utilizing already established industrial databases in Busan, Ulsan and Gyeongnam. But, various issues caused by the discordances among the data of each local government and the insufficiency of GIS based location information have been found. According to the analysis, the standardization considering the courses of collection, distributions and utilization are required immediately to solve the issues. This study establishes an 2-way industrial information system enabling the information creation and the phased approach between the administrator and the user in the bi-directions on the web by utilizing cadastral and numerical maps. The result of this study would have a meaning in providing a fundamental frame for cooperative responses and cooperation system for DongNam Kwon``s industrial promotion using industrial information sharing.

      • Hypoxia-Responsive MicroRNA-101 Promotes Angiogenesis <i>via</i> Heme Oxygenase-1/Vascular Endothelial Growth Factor Axis by Targeting Cullin 3

        Kim, Ji-Hee,Lee, Kwang-Soon,Lee, Dong-Keon,Kim, Joohwan,Kwak, Su-Nam,Ha, Kwon-Soo,Choe, Jongseon,Won, Moo-Ho,Cho, Byung-Ryul,Jeoung, Dooil,Lee, Hansoo,Kwon, Young-Guen,Kim, Young-Myeong Mary Ann Liebert 2014 Antioxidants & redox signaling Vol.21 No.18

        <P>Aims: Hypoxia induces expression of various genes and microRNAs (miRs) that regulate angiogenesis and vascular function. In this study, we investigated a new functional role of new hypoxia-responsive miR-101 in angiogenesis and its underlying mechanism for regulating heme oxygenase-1 (HO-1) and vascular endothelial growth factor (VEGF) expression. Results: We found that hypoxia induced miR-101, which binds to the 3 ' untranslated region of cullin 3 (Cul3) and stabilizes nuclear factor erythroid-derived 2-related factor 2 (Nrf2) via inhibition of the proteasomal degradation pathway. miR-101 overexpression promoted Nrf2 nuclear accumulation, which was accompanied with increases in HO-1 induction, VEGF expression, and endothelial nitric oxide synthase (eNOS)-derived nitric oxide (NO) production. The elevated NO-induced S-nitrosylation of Kelch-like ECH-associated protein 1 and subsequent induction of Nrf2-dependent HO-1 lead to further elevation of VEGF production via a positive feedback loop between the Nrf2/HO-1 and VEGF/eNOS axes. Moreover, miR-101 promoted angiogenic signals and angiogenesis both in vitro and in vivo, and these events were attenuated by inhibiting the biological activity of HO-1, VEGF, or eNOS. Moreover, these effects were also observed in aortic rings from HO-1(+/-) and eNOS(-/-) mice. Local overexpression of miR-101 improved therapeutic angiogenesis and perfusion recovery in the ischemic mouse hindlimb, whereas antagomiR-101 diminished regional blood flow. Innovation: Hypoxia-responsive miR-101 stimulates angiogenesis by activating the HO-1/VEGF/eNOS axis via Cul3 targeting. Thus, miR-101 is a novel angiomir. Conclusion: Our results provide new mechanistic insights into a functional role of miR-101 as a potential therapeutic target in angiogenesis and vascular remodeling. Antioxid. Redox Signal. 21, 2469-2482.</P>

      • 고성능 유도 전동기를 위한 퍼지 속도 제어기

        권병휘,全光鎬,崔秉淑,鄭雨均 홍익대학교 산업기술연구소 1997 産業技術 Vol.7 No.-

        In this dissertation a novel speed control system that implements the fuzzy logic controller(FLC) is proposed. The proposed FLC used the speed error its rate of change, and the drive current as three fuzzy variables. The real command output current is chosen by the defuzzification of fuzzy output extracted from the fuzzy control rules. The flex and the torque of the induction motor are estimated using the dynamic model with an excellent dynamic response over a wide speed range and with the rotor flux field-oriented scheme of the decoupling characteristics The performance of this control system is substantiated by computer simulations.

      • 境界要素法에 의한 3次元 基礎一地盤 相互作用 시스템의 地震解析

        權映錄,宋始榮,姜圓鎬,崔光圭,柳又秀 동아대학교 공과대학 부설 한국자원개발연구소 1990 硏究報告 Vol.14 No.1

        In this study, the seismic analysis procedure of foundation-soil interaction system is presented. With the assumption of isotropic material properties and infinitesimal strain theory, the boundary element models of three dimensional foundation plate an semi-infinite soil medium are coupled together, using the compatiblity condition of displacements and equilibrium condition of surface tractions on the contact surface. Through the results of the examples in which the seismic responses of the foundation subjected to the SV-wave and the P-Wave, it is shown that the translational motions are decreased and the rocking motion is occured in higher frquency range.

      • 종이상자포장기의 개발에 관한 연구

        권경우,권병철,류봉조,명태식,박찬호,이광원 한밭대학교 산업과학기술연구소 1994 논문집 Vol.2 No.-

        The paper describes the development of a new automatic wrapping machine using paper films as it has not been used so far. The most of the automatic wrapping machine have used the vinyl film causing environmental pollution, the paper films, however, have a weak point in the aspect of high temperature adhesion. Therefore, the mechanism of the existing wrapping machine should be altered to prevent it from curling effect through the technical know-how. A new method and technology reducing the curling effect in the automnatic wrapping machine are demonstrated by using developed blower. Thus it is exqection and will decrease environmental pollution.

      • KCI등재

        공정변수의 변동을 고려한 호감도 함수를 통한 다중반응표면 최적화

        권준범,이종석,이상호,전치혁,김광재 한국경영과학회 2005 한국경영과학회지 Vol.30 No.1

        A desirability function approach to a multiresponse problem is proposed considering process parameter fluctuation which may amplify the variance of response. It is called POE(propagation of error), which is defined as the standard deviation of the transmitted variability in the response as a function of process parameters. In order to obtain more robust process parameter setting, a new desirability function is proposed by considering POE as well as distance-to-target of response and variance. The proposed method is illustrated using a rubber product case in Ribeiro et al. (2000).

      • 철근콘크리트 부재의 전단변형 해석에 관한 연구

        최광진,장일영,권종주,송재호 金烏工科大學校 1994 論文集 Vol.15 No.-

        The object of this study is to present an analytical method using superposition of displacement due to flexural crack and diagonal tension crack in reinforced concrete members. Flexural displacement caused by bending moment could be found by the double integration of curvature derived from the relationship between moment and curvature. The macro model of shear deformation from the viewpoint of diagonal tension crack occurrence and its development has been developed. The rotational angle due to diagonal tension crack could be evaluated by using strain compatibility, force equilibrium and moment equilibrium. Furthermore the bonding characteristics between concrete and steel as well as the characteristics of dowell have been taken into consideration. The theoretical values calculated using the analytical method developed in this study have been investigated in comparison with the experimental ones which were carried out earlier in order to prove it s validity. From the results it has been shown that theoretical values agree quite well with experimental ones, and it could be pointed out that presented analytical method is widely acceptable for the practical analysis of flexural displacement of reinforced concrete members.

      • HDPE 개질 아스팔트 혼합물의 강도 및 변형특성

        김광우,이기호,권오선,고태영 강원대학교 부설 석재복합신소재 제품연구센터 2004 석재연 논문집 Vol.9 No.-

        본 연구는 폐비닐 펠렛을 도로포장재료로 재활용하여 자원절약 및 아스팔트 혼합물의 품질향상을 위한 연구이다. 이를 위하여 폐비닐의 첨가량별 배합설계를 수행하여 적정 폐비닐 첨가량과 최적 아스팔트 함량으로 편마암과 화강암 2가지 골재와 폐비닐인 RHDPE의 함량을 4가지로 혼합물을 제작하여 8종류의 재질 혼합물과 2종류의 무개질 혼합물을 제작하였다. 그리고 이 공시체에 대하여 마샬안정도, 간접인장강도 및 Kim test와 반복주행시험 등 실내시험을 통하여 혼합물의 특성을 분석하였다. 폐비닐 첨가량은 RHDPE가 8%일 때 안정도와 간접인장강도 모두 가장 우수한 것으로 나타났고 취성도 나타나지 않았다. RHDPE를 첨가한 혼합물에 대하여 Kim test를 수행한 결과 DR과 DS 모두 높은 상관성을 보였다. 그리고 반복주행시험에서는 RHDPE를 첨가한 혼합물이 일반 혼합물보다 우수하였다. 향후 많은 실험을 통해 RHDPE의 우수성을 입증한다면 소성변형 저항성에 우수한 재료로 이용될 수 있을 것이다. This study is a fundamental research for recycled high-density polyethylene (RHDPE) in asphalt mixture for improving roadway pavement. Marshall mix design was conducted and optimum asphalt content(OAC) was determined for dense-graded surface course mixture by RHDPE content. Marshall stability test, indirect tensile strength (ITS) test, wheel tracking trest and Kim-test were carried out to measure the characteristics of RHDPE-added asphalt concretes. From the results of this study, RHDPE in asphalt mixture if possible. It could be considered that adding too much RHDPE in asphalt mixture is not proper. The optimum content of RHDPE was appeared to be 8%. In Kim-test, statistical analysis was performed for each loading head and aggregate to find out correlation between S_(D) values and each rut parameter. The analysis result showed that S_(D) had very high coefficient of determination with rut parameters on the average.

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