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        The relationship between abnormal intracranial findings in brain computed tomography and antiplatelet or anticoagulant use in patients with nontraumatic headache: a prospective cohort study

        Iskorur Caner,Korkut Mustafa,Soyuncu Secgin 대한응급의학회 2022 Clinical and Experimental Emergency Medicine Vol.9 No.2

        Objective This study aimed to investigate the relationship between abnormal intracranial findings on brain computed tomography and antiplatelet or anticoagulant use in patients with nontraumatic headache in the emergency department (ED).Methods This was a single-center prospective observational study of patients admitted to the tertiary ED with complaints of nontraumatic headache between May 1, 2016 and September 1, 2016. Anticoagulant or antiplatelet drug use by the patient was recorded. Brain computed tomography (CT) results were categorized into two groups, abnormal results (CT positive) and no pathologic results (CT negative), and compared. The CT positive group included any pathological signs in the brain and the negative group was considered a normal read. A logistic regression analysis was used for evaluating the association of antiplatelets and anticoagulants with abnormal CT findings.Results Of the 837 patients with nontraumatic headaches, 157 (18.8%) patients who underwent brain CT scanning were included. The mean age of the patients was 44.4±16.7 years. Eighty-eight (56.1%) of the patients were women. Of the 29 (18.4%) patients using antiplatelets or anticoagulants, 16 (55.2%) were in the CT positive group. There was a statistically significant difference between both groups in terms of drug use compared to the CT negative group (P<0.001). Factors affecting CT results were examined in logistic regression analysis and a statistically significant difference was found in the detection of positive results in antiplatelet or anticoagulant drug users (adjusted odds ratio, 2.478; 95% confidence interval, 1.006–6.102; P=0.048).Conclusion The use of antiplatelets or anticoagulants in patients admitted to the ED with nontraumatic headache is associated with an increased risk of abnormal intracranial results in brain CT.

      • KCI등재

        Impact of nuclear and renewable energy sources on environment quality: Testing the EKC and LCC hypotheses for South Korea

        Pata Ugur Korkut,Kartal Mustafa Tevfik 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.2

        This study investigates the impacts of nuclear energy consumption on environmental quality from a different perspective by focusing on carbon dioxide (CO2) emissions, ecological footprint, and load capacity factor. In this context, the South Korea case, which is a leading country producing and consuming nuclear energy, is investigated by considering also economic growth, and the 1997 Asian crisis from 1977 to 2018. To this end, the study employs the autoregressive distributed lag (ARDL) approach. Different from previous literature, this study proposes a load capacity curve (LCC) and tests the LCC and environmental Kuznets curve (EKC) hypotheses simultaneously. The analysis results reveal that (i) the LCC and EKC hypotheses are valid in South Korea; (ii) nuclear energy has an improving effect on the environmental quality; (iii) renewable energy does not have a significant long-term impact on the environment; (iv) the 1997 Asian crisis had an increasing effect on the load capacity factor; (v) South Korea has not yet reached the turning point, identified as $55,411, where per capita income improves environmental quality. Overall, the results show the validity of the LCC and EKC hypotheses and prove the positive contribution of nuclear energy to South Korea's green development strategies.

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        No Adverse Outcomes of Video-Assisted Thoracoscopic Surgery Resection of cT2 Non-Small Cell Lung Cancer during the Learning Curve Period

        Zeynep Bilgi,Hasan Fevzi Batırel,Bedrettin Yıldızeli,Korkut Bostancı,Tunç Laçin,Mustafa Yüksel 대한흉부외과학회 2017 Journal of Chest Surgery (J Chest Surg) Vol.50 No.4

        Background: Video-assisted thoracoscopic surgery (VATS) anatomic lung resections are gradually becoming the standard surgical approach in early-stage non-small cell lung cancer (NSCLC). The technique is being applied in cases of larger tumors depending on the experience of the surgical team. The objective of this study was to compare early surgical and survival outcomes in patients undergoing anatomic pulmonary resections using VATS and thoracotomy techniques for clinical T2 NSCLC during the adaptation period of the surgical team to the VATS approach. Methods: The data of all patients who underwent anatomic pulmonary resection for NSCLC using VATS and open techniques since April 2012 were recorded to create a prospective lung cancer database. Clinical T2 NSCLC patients who underwent VATS anatomic lung resection were identified and compared with cT2 patients who underwent open resection. Results: Between April 2012 and August 2014, 269 anatomical resections for NSCLC were performed (80 VATS and 189 thoracotomy). Thirty-four VATS patients who had clinical T2 disease were identified and stage-matched to thoracotomy patients. The average tumor diameter was comparable (34.2±11.1×29.8±10.1 mm vs. 32.3±9.8×32.5±12.2 mm, p=0.4). Major complications were higher in the thoracotomy group (n=0 vs. n=5, p=0.053). There was no 30-day mortality, and the 2-year survival rate was 91% for VATS and 82% for thoracotomy patients (p=0.4). Conclusion: VATS anatomic resections in clinical T2 NSCLC tumors are safe and have perioperative and pathologic outcomes similar to those of thoracotomy, while remaining within the learning curve.

      • KCI등재

        Validity and Reliability of the Turkish Version of the Nuss Questionnaire Modified for Adults

        A. Tugba Bahadir,Pinar Kuru,Ceyda Afacan,Nezih Onur Ermerak,Korkut Bostanci,Mustafa Yuksel 대한흉부외과학회 2015 Journal of Chest Surgery (J Chest Surg) Vol.48 No.2

        Background: Pectus excavatum (PE) is the most common chest wall deformity. The Nuss Questionnaire modifiedfor Adults (NQmA) is a disease-specific health-related quality of life assessment tool for patients with pectusdeformities. The aim of this study is to adapt the NQmA into Turkish. Methods: Two hundred and sixty-five patientswith PE were participated, with an age range of 14 to 29 years. All patients underwent a physical examinationand had not undergone corrective surgery. The Turkish version of the NQmA was completed by patients andtheir parents. Results: The content validity index based on expert opinions was 91% for the patient questionnaireand 96% for the parent questionnaire. The Cronbach’s alpha value for the NQmA was found to be 0.805 for thepatient questionnaire and 0.800 for the parent questionnaire. Exploratory factor analysis was used to assess constructvalidity. Two factors explained 51.1% of the total variance in the patient questionnaire (psychosocial:31.145%, Cronbach’s alpha=0.818; physical: 19.955%, Cronbach’s alpha=0.862). In the parent questionnaire, two factorsexplained 51.422% of the total variance (psychosocial: 26.097%, Cronbach’s alpha=0.743; physical: 25.325%,Cronbach’s alpha=0.827). Construct validity was confirmed by confirmatory factor analysis. Conclusion: The Turkishversion of the NQmA was found to be valid and reliable for the assessment of quality of life in patients with PE.

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