일부 대학생의 계통별 VDT 증후군 자각증상에 대한 조사

김근조 ; 이규리 ; 박지원 ; 박재영 김천대학교 2005 김천대학교 논문집 Vol.26 No.-

IIn order to find out the actual conditions and habit of using computer and the related VDT subjective symptom, we have done a survey though a random questionnaire of roughly 350 students of Kimchon college for the period of May 9 - June 18, 2005.

장애청소년 어머니의 삶의 질 변인 연구

이규리 ; 김근조 김천대학교 2004 김천대학교 논문집 Vol.25 No.-

Mothers who raise children with disabilities experience various types of fostering stresses that can affect them mentally, physically, psycho-logically and socially. This study attempted to analyze the quality of life for mothers of children with disabilities, consequently aiming at con-tributing to the development of an arbitration strategy that would help to improve the quality of life for mothers of children with disabilities in educational fields and local communities. In the study, variables included self-efficacy, social support the ability to cope with situations, physical health mental health and quality of life of mothers and behavioral characteristics, functional characteristics. medical symptoms, economic circumstances and intellectual level of chil-dren with disabilities. There were 13 measurement variables for these theoretical variables, and we used measuring instruments after analyzing their credibility through preliminary tests. The data for testing the model have been collected through structural questionnaires distributed to 420 mothers of children with disabilities attending general schools and special schools for handicapped students located in Seoul and Kyonggi Province between March 13 and April 10, 2004. We used the SPSS 10.0 Win Program for compiling descriptive statis-tics and analyzing correlations. Specifically, it proved that the variables that exert direct influence on the quality of life for mothers of children with disabilities to a statisti-cally significant extent were the mental health, self-efficacy, social sup-port. physical health, the capability of mothers to cope with situationsand families financial situations. ​It proved that the variables that exert direct influence on the moth-ers mental health were inothers' physical health, self-efficacy, social support and families financial situations. The variables that directly exert influence on mothers physical health to a statistically significant extent were self-efficacy, social support and families financial situations in that order. The variables that directly exert influence on the capability of mothers to cope with situations to a statistically significant extent were, in order, self-efficacy, social support, families financial situations and physical characteristics of children with disabilities.

가정방문 물리치료제도의 필요성에 대한 연구

이규리 ; 김진 ; 박재영 김천대학교 2005 김천대학교 논문집 Vol.26 No.-

As the desire for better medical service was increased, the home visiting physical therapy system has been considered one of the alternative medical services which was adequate to the public health and medical system.

복합부위 통증증후군에 대한 고찰

이규리 ; 김근조 ; 오희종 김천대학교 2008 김천대학교 논문집 Vol.29 No.-

Complex regional pain syndrome type I, formerly known as reflex sympathetic dystrophy and complex regional pain syndrome type II, formetly formerly known as causalgia, are debilitating pain syndroms that have recognized for more than a century. Complex regional pain syndroms remains a poorly understood chronic pain condition with regards to patho-physiology and treatment. According to the International Association for the study of Pain criteria, the characteristic frature required to establish the diagnosis of complex regional pain syndrome type I are as follows: (1) the presence of an initiating noxious event or a cause of immobilization; (2) continuing pain, allodynia; (3) evidence at some time of edema, change in blood flow; and (4) the exclusion of medical conditions thath would account for the degree of pain and dysfuntion. Therapies for complex regional pain syndrome type I are guided by the recogntion of the complex interaction between approach. In general, there is an incremental incorporation of therapeutic measures that combine aspects of physio-therapeutic, pharmace-therapeutic measures chotherapeutic modalites. But the patho-physiologic mechanisms of complex aging the signs and stmptoms of the disease. Nevertheless, no specific personality development of complex regional pain syndrome. Therefore we have to study the new research criteria to refine many smples in clinical reseach to establish efficacy of treatment.

한국형 출혈열 환자에서 분리한 한타 바이러스의 핵산 분석

조종태,윤성철,안규리,한진석,김성권,이정상 단국대학교 1998 論文集 Vol.33 No.-

Hemorrhagic fever with renal syndrome(HFRS)is an infectious disease showing diverse clinical manifestations according to different serotypes of hantavirus. On the assumption that the antigenicity, nucleotide and amino acid sequence diversity of hantaviruses, as well as immune response diversity of individual KHF patients may be present, this study was performed to analyse the genetic diversity of hantaviruses isolated from patients with KHF. In the 13 samples hantaviral RNAs were extracted, cDNAs of partial M segment were amplified by RT-PCR using genus-reactive primer, amplified cNNAs were analyzed by direct sequencing method, and then the nucleotide and deduced amino acid sequences were compared with previously known sequences of four serotypes of hantavirus isolated from rodent hosts and each other by the computer assistance. The results were as follows. The nucleotide and amino acid sequences of 11 samples among the 13 human isolates showed 90.3∼95.5%, 86.7∼97.9% the other 1 samples 82.7%, 71.9% homology respectively to those of Hantaan virus 76-118 strain, and another 1 sample showed 83.7%, 75.3% homology respectively to those of Seoul virus B1 strain isolated from rodent host. The nucleotide and amino acid sequences of 7 among 12 Hantaan samples showed differences within 5%, 10% respectively each other and high genetic similarities, but those of the oehr 5 among 12 Hantaan samples showed low genetic similarities each other. In conclusion, hantaviruese isolated from KHF patients showed genetic diversity compared with previously known hantaviruses isolated from rodent hosts.

조혈모세포 이식 후 발생한 급성 신부전의 원인과 급성 신부전이 예후에 미치는 영향

김세중(Se Joong Kim),김성균(Seong Gyun Kim),오윤규(Yoon Kyu Oh),김현리(Hyun Lee Kim),김연수(Yon Su Kim),안규리(Cu Rie Ahn),한진석(Jin Suk Han),박선양(Seon Yang Park),김성권(Shung Gwon Kim),김병국(Byoung Kook Kim),이정상(Jung Sang Lee 대한신장학회 2002 Kidney Research and Clinical Practice Vol.21 No.3

배 경 : 조혈모세포 이식(hematopoietic stem cell transplantation; HCT) 후 합병증으로 패혈증(sepsis), 이식편대숙주반응(graft versus host disease; GVHD), 정맥폐색성 질환(venoocclusive disease; VOD), 약물에 의한 부작용(drug induced nephrotoxicity; DT), 급성 신부전(acute renal failure; ARF) 등이 있다. HCT 후 발생하는 ARF는 환자의 생존율에 영향을 미치는 것으로 알려져 있으나 우리나라에서의 연구는 미흡한 실정이다. 저자들은 HCT 후 ARF의 발생빈도, 위험인자를 살펴보고, ARF의 발생이 HCT 후 환자의 예후에 미치는 영향을 알아보고자 본 연구를 시행하였다. 방 법 : 1985년부터 2000년까지 서울대학교병원에서 HCT를 받은 환자 163명 중 분석이 가능하였던 107명을 대상으로 하였다. 결 과: HCT 후 ARF는 총 107명의 환자 중 52명(48.6%)에서 발생하였다. VOD, sepsis, GVHD 중 VOD가 ARF의 위험도를 4.4(1.13-17.2)배 증가시켰다(p<0.05). ARF의 원인은 시기에 따라 차이가 있었으나, cyclosporin 신독성이 전 기간에 걸쳐 ARF의 주된 원인이었다. ARF 발생군에서 전체 생존율은 60%였으며, ARF 비발생군(NARF)에서는 73%로, ARF 발생군에서 생존율이 낮았다(p<0.05). ARF 발생군을 최고 혈청 크레아티닌 3.0 ㎎/dL을 기준으로 경증과 중증 ARF로 나누어, NARF 군, 경증 ARF 발생군, 중증 ARF 발생군을 비교하였을 때, 중증 ARF 발생군에서 생존율이 낮았다(p<0.01). 결 론 : HCT 후 VOD, sepsis, GVHD 등이 ARF의 위험도를 증가시켰으나, ARF의 주된 원인은 cyclosporin 신독성이었다. ARF는 중증인 경우 HCT를 받은 환자의 예후를 결정하는 인자였다. Background : Common complications after hematopoietic stem cell transplantation(HCT) include sepsis, graft versus host disease(GVHD), veno-occlusive disease(VOD), drug-induced nephrotoxicity, and acute renal failure(ARF). Prior studies report that the presence of ARF affects prognosis. However, we are unaware of such reports on the incidence of ARF after HCT in Koreans, and whether or not the development of ARF is related to prognosis. The purpose of our study was to investigate the cause of ARF after HCT and its relation to prognosis. Methods : 163 patients received HCT at Seoul National University Hospital since 1985, of which, 107 were available for review. Results : ARF after HCT developed in 52 patients (48.6%). In the three clinical causes, VOD, sepsis, and GVHD, risk factor related to the development of ARF was preexisting VOD. Logistic regression confirmed this association(odds ratio 4.4). The causes of ARF were different according to the periods it developed, and cyclosporin nephrotoxicity was the main cause through the whole period after HCT. The overall survival was worse in the ARF group(60 vs 73 %; p<0.05). ARF group was split into two groups : patients whose peak serum creatinine levels were below 3.0 ㎎/dL(mild ARF group) and those who were above 3.0 ㎎/dL(severe ARF group). Severe ARF group had worse survival than mild ARF group and patients without ARF(p<0.01). Conclusion : VOD, sepsis, GVHD after HCT increase the risk of the deveolopment of ARF, but cyclosprin nephrotoxicity is the main cause of ARF. Severe ARF is a factor influencing the prognosis of patients who received HCT.

Peritoneal Dialysis 2 : Clinical Benefits of a Low Glucose Degradation Products Solution in Patients Starting Peritoneal Dialysis: Preliminary Report

( Se Joong Kim ),( Seong Gyun Kim ),( Ji Eun Oh ),( Woo Kyung Chung ),( Kook Hwan Oh ),( Yon Su Kim ),( Cu Rie Ahn ),( Jin Suk Han ),( Suhng Gwon Kim ),( Jung Sang Lee ) 대한신장학회 2006 춘계학술대회 초록집 Vol.25 No.1

성인의 원발성 초점성 분절성 사구체 경화증 ( FSGS ) 의 예후 및 예후 인자

김연수(Yon Su Kim),안규리(Cu Rie Ahn),한진석(Jin Suk Han),김성권(Shung Gwon Kim),이정상(Jung Sang Lee),김성균(Seong Gyun Kim),김현리(Hyun Lee Kim),황영환(Young Hwan Hwang),이상구(Sang Goo Lee),이정은(Jung Eun Lee),오윤규(Yun Kyu Oh) 대한신장학회 2002 Kidney Research and Clinical Practice Vol.21 No.4

배 경: 성인에서 FSGS는 그 발생율이 증가하고 지속적인 스테로이드 치료로 예후가 향상됨이 제시되면서 질병에 대한 관심이 높아지고 있다. 그러나 우리나라 성인 FSGS의 임상상과 예후에 대한 보고는 많지 않다. 본 연구에서는 성인 FSGS의 임상상을 살펴보고 예후에 관계하는 임상 인자를 밝히고자 하였다. 방 법 : 1985년부터 1999년까지 서울대학교병원에서 조직검사로 확진된 성인 환자를 대상으로 연구를 진행하였고 이차적 원인이 있는 경우는 제외하였다. 조직검사 당시의 임상상을 분석하였고, 10주 이상 추적 관찰된 환자를 대상으로 신기능 악화여부를 후향적으로 분석하였다. 결 과: 대상 환자는 총 92명이였으며, 이 중 47명(51%)이 신증후군(NS) 범주에 속하였다. 남녀비는 1.7 : 1이였으며 조직검사시 신기능 저하가 51%에서 관찰되었고 고혈압은 45%에서 나타났다. NS군과 신증후군 이하의 단백뇨군(non-NS)간에 고혈압유무, 신기능 저하 등의 초기 임상상의 차이는 없었다. 이들 중, 10주 이상 추적 관찰된 환자는 88명이였고, 관찰 기간은 37.1개월(2.5-185)이였다. 관찰 기간동안 14명에서 신기능이 악화되었다. 신기능 악화군과 유지군간에 조직 진단시 임상상의 차이는 없었으며, 신기능 악화 여부에 대한 독립적 예후 인자는 단백 뇨량의 정도와 조직 검사시의 신기능, 스테로이드 치료 여부였다. 전체적으로 5년 신기능 유지율은 80%로 나타났다. NS군에서 스테로이드 치료를 한 환자는 77%(34/44명)이였으며 그 중 1명(3%)에서 신기능 악화소견을 보였다. NS군에서 스테로이드 치료를 하지 않은 10명 중 6명(60%)의 신기능이 악화되었다. 결 론 : 위의 결과에서 밝혀진 성인 FSGS 환자의 예후 인자에 대한 적극적인 조절이 필요하며 향후 스테로이드 치료법의 유용성을 확인하기 위한 전향적인 연구가 필요하다. N/A

혈액투석 : 말기 신부전 환자에서 내부생성 재주입 혈액투석여과요법을 통한 요독물질의 효과적인 제거

김세중 ( Se Joong Kim ),김선문 ( Sun Moon Kim ),오국환 ( Kook Hwan Oh ),주권욱 ( Kwon Wook Joo ),김연수 ( Yon Su Kim ),안규리 ( Cu Rie Ahn ),한진석 ( Jin Suk Han ),김성권 ( Suhng Gwon Kim ),진호준 ( Ho Jun Chin ),나기영 ( Ki Young 대한신장학회 2008 춘계학술대회 초록집 Vol.28 No.1

성인 지속성 외래 복막투석 환자의 생존에 영향을 미치는 인자

김기원,이정상,정우경,양재석,한진석,김성권,김강석,황영환,안규리,오윤규,김연수,이상구,이중건,이경이 대한신장학회 1999 Kidney Research and Clinical Practice Vol.18 No.5

As a single CAPD center in Korea, we, at the department of internal medicine, Seoul National University Hospital, conducted a retrospective study in CAPD patients for the causes of death, patient survival rate, technique success rate, and risk factors. We enrolled in our study 167 patients who had began CAPD as an initial replacement therapy for end stage renal disease from March 1992 to July 1997 and survived for more than 2 months. As the prognostic factors of patient survival and technique success, we analyzed demographic features, clinical features including comorbid conditions at the beginning of CAPD, and laboratory findings at the beginning and 6 months after the start of CAPD. The mean age of patients was 49.8 12.5, and sex ratio was 1.4: 1(M: F). The mean follow-up period was 24.0±14.4 months. Cerebrovasular accident(CVA), the patient giving up on the treatment, cardiac diseases and peritonitis were the main causes of death in CAPD patients. Among the causes of death, although CVA and the patient giving up on the treatment were relatively important, the most important causes of death were cardiovascular diseases. The 2 year survival rate and 4 year survival rate of CAPD patients were 89.4% and 55.57% respectively ; the 2 year technique success rate and 4 year technique success rate of CAPD were 87.37% and 63.18% respectively ; and the mean survival period and technique success period were 50.57±2.42 and 49.37±2.85 rnonths, respectively. We determined the independent prognostic factors for patient survival to be diabetes mellitus$lt;DM$gt;(p=0.0004, relative risk$lt;RR$gt;=5.9263) and liver cirrhosis(p=0.0032, RR=5.3211) using multivariate analysis with Cox proportional hazard model. Although the results were statistically insignificant, the patients with cardiac diseases(p=0.0961, RR= 2.0116) and older patients who were over 60 years old(p=0.1312, RR=1.8431) had a poor prognosis. The probable prognostic factors for 2 year survival of patients, considered marker of risk factors for early death, were DM, liver cirrhosis, and cardiac diseases, though statistically insignificant, and they were similar to prognostic factors for the patient survival during the entire period. The independent prognostic factor of technique failure of CAPD was DM(p= 0.0150, RR=2.6762). The patient survival rate and technique success rate of CAPD patients were similar to the outcomes reported in other countries. However, the fact that liver cirrhosis was included as one of the independent prognostic factors seems to reflect a disease characteristic of Korean population in whom chronic liver diseases are prevalent. Due to ever increasing proportions of DM, cardiac diseases, and older patients in CAPD patients and the prevalence of liver cirrhosis in Korea, more intensive management is necessary for CAPD patients with these disorders/ conditions.