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      • The Impact of Tourism Development in Lijiang City, China

        Mayumi Matsuura,Kazuo Ichikawa 실천경영학회 2011 실천경영연구 Vol.6 No.1

        Tourism industry is a source of foreign currency acquirement and promotes employment of new workers. Hence, tourism development is able to become an effective tool to reduce poverty and achieve economic development in developing countries. However, as economy grows, the environment is apt to be harmed by an influx of tourists and merchants from outside. Wherein, this research showed major environmental issues, such as water pollution and lack of water supply, and revealed economic effects in the case of Lijiang City, China. Estimates economic effect, tourism industry has produced 25.526 billion RMB of the total amount of economic effect and 259,874 people of the total number of employed workers by tourists’ consumption expenditures.

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        Genomic Profiling Shows Increased Glucose Metabolism in Luminal B Breast Cancer

        Shigeto Ueda,Hideki Takeuchi,Takashi Shigekawa,Kazuo Matsuura,Noriko Nakamiya,Hiroshi Sano,Hiroko Shimada,Eiko Hirokawa,Akihiko Osaki,Toshiaki Saeki 한국유방암학회 2013 Journal of breast cancer Vol.16 No.3

        We had previously reported a close association between pathological response and the maximum tumor standardized uptake value (SUVmax) measured by 18F-fluorodeoxyglucose positron emission tomography prior to chemotherapy in estrogen receptor (ER)-positive breast cancer. We hypothesized that glucose hypermetabolism by luminal B tumors may result in chemotherapy responsiveness. Using a single-gene expression assay, TargetPrint® (Agendia) and a 70-gene expression classifier,MammaPrint® (Agendia), we divided 20 patients with ERpositive primary breast cancer into luminal A and luminal B subtypes and compared the tumor SUVmax value between the two groups. A significantly higher SUVmax was measured for luminal B tumors (n=10; mean±SD, 7.6±5.6) than for luminal A tumors (n=10; mean±SD, 2.6±1.2; p=0.01). Glucose hypermetabolism could help predict intrinsic subtyping and chemotherapy responsiveness as a supplement to ER, progesterone receptor, HER2,and Ki-67 histochemical scores.

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