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RISS 인기검색어
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- 저자 : Kai C. Wong (검색결과 3 건)
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Ming-Wun Wong,I-Hsuan Lo,Wei-Kai Wu,Po-Yu Liu,Yu-Tang Yang,Chun-Yao Chen,Ming-Shiang Wu,Sunny H Wong,Wei-Yi Lei,Chih-Hsun Yi,Tso-Tsai Liu,Jui-Sheng Hung,Shu-Wei Liang,C Prakash Gyawali,Chien-Lin Che 대한소화기 기능성질환∙운동학회 2024 Journal of Neurogastroenterology and Motility (JNM Vol.30 No.3
Background/AimsIneffective esophageal motility (IEM) is common in patients with gastroesophageal reflux disease (GERD) and can be associated with poor esophageal contraction reserve on multiple rapid swallows. Alterations in the esophageal microbiome have been reported in GERD, but the relationship to presence or absence of contraction reserve in IEM patients has not been evaluated. We aim to investigate whether contraction reserve influences esophageal microbiome alterations in patients with GERD and IEM. MethodsWe prospectively enrolled GERD patients with normal endoscopy and evaluated esophageal motility and contraction reserve with multiple rapid swallows during high-resolution manometry. The esophageal mucosa was biopsied for DNA extraction and 16S ribosomal RNA gene V3-V4 (Illumina)/full-length (Pacbio) amplicon sequencing analysis. ResultsAmong the 56 recruited patients, 20 had normal motility (NM), 19 had IEM with contraction reserve (IEM-R), and 17 had IEM without contraction reserve (IEM-NR). Esophageal microbiome analysis showed a significant decrease in microbial richness in patients with IEM-NR when compared to NM. The beta diversity revealed different microbiome profiles between patients with NM or IEM-R and IEM-NR (P = 0.037). Several esophageal bacterial taxa were characteristic in patients with IEM-NR, including reduced Prevotella spp. and Veillonella dispar, and enriched Fusobacterium nucleatum. In a microbiome-based random forest model for predicting IEM-NR, an area under the receiver operating characteristic curve of 0.81 was yielded. ConclusionsIn symptomatic GERD patients with normal endoscopic findings, the esophageal microbiome differs based on contraction reserve among IEM. Absent contraction reserve appears to alter the physiology and microbiota of the esophagus.
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Sang-Heon Lee,Ill-Soo Kim,Kai C. Wong 한국정밀공학회 2004 International Journal of Precision Engineering and Vol.5 No.2
A problem of task rescheduling using a coordinator in a structural decentralized control of supervisory control theory is formulated. we consider that the overall system is divided into a number of local systems. Using an example of a chemical batch reaction process, it has shown that after local supervisors have been established for a given task, a coordinator can be used to solve some rescheduling problems among local plants for new or modified tasks. The coordination system models the interactions of local plants, and is consisting of only the shared events of local plants, so simpler to synthesize. A coordinator is designed based on the specifications given for the coordination system. Under the 'structural' conditions developed in this paper, the combined concurrent actions of the coordinator with the existing local supervisors will achieve the rescheduling requirements. Again since the conditions are structural (not specification-dependent), once the coordination architecture has been established, it can be used for a number of different tasks without further verifications.
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Huai M. Ooi,Pei L. Teh,Cheow K. Yeoh,Wee C. Wong,Chong H. Yew,Xue Y. Lim,Kai K. Yeoh,Nor A. Abdul Rahim,Chun H. Voon Techno-Press 2024 Advances in materials research Vol.13 No.3
Waste tire management and recycling have grown to be significant issues because they bring up a global environmental concern. Thus, turning recycled waste tires into useful products may help tackle the environmental issue. This research aims to study and compare the effect of recycled carbon black (rCB) and commercial carbon black (CB) at certain 15 vol. % of filler loading on the mechanical, thermal, morphology and electrical properties of epoxy/CB composites. For this project, epoxy resin, diethyltoluenediamine (DETDA), recovered carbon black (rCB) and commercial carbon black (CB) graded N330, N550, N660 and N774 were mixed and compared accordingly to the formulation determined. The CB content was dispersed in the epoxy matrix using the mechanical mixing technique. The distribution and dispersion of CB in the epoxy matrix affect the characteristics of the conductive composites. rCB content at 15 vol% was selected at fixed content for comparison purposes due to the optimum value in electrical conductivity results. The flexural strength results followed the sequence of rCB>N774>N660>N550>N330. As for electrical conductivity results, epoxy/N330 exhibited the highest conductivity value, while the others achieved a magnitude of X10<sup>-3</sup> due to the highest external surface area of N330. In terms of thermal stability, epoxy/N330 and epoxy/N774 were slightly more stable than epoxy/rCB.
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