서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1994)

김재홍,안진균,정성재,김영태,김중환,김시영,이석종,이홍렬,서호석,김경훈,권혁진,정우권,고우석,이용석,안필수,오준규,오용섭 대한화학요법학회 1996 대한화학요법학회지 Vol.14 No.1

Background : In recent years gonorrhoea has been panendemic and remains one of the most common Sexually Transmitted Diseases in the world, especially in developing countries. Objective & Method : For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria Gonorrhoeae(PPNG), Ive have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1994, 168 strains of N. gonorrhoeae were isolated, among which 109 (64,9% ) were PPNG. Conclustion : Our results suggests that the prevalence of PPNG in Seoul is still increasing.

자궁내막에 발생한 점막 연관 림프조직 (MALT) 림프종 1예

전균호,조현진,박성균,김천복,김대연,김종혁,김용만,김영탁,목정은,남주현 대한부인종양 콜포스코피학회 2003 Journal of Gynecologic Oncology Vol.14 No.4

Non-Hodgkin's 림프종의 약 40%는 결절외(extranodal) 림프종으로 대개 위장관에서 발생하며 이들 중 점막 연관 림프조직(mucosa-associated lymphoid tissue: MALT)에서 기원한 림프종은 MALT 림프종으로 분류된다. 위 외의 부위에서 원발성으로 발생하는 MALT 림프종은 매우 드물지만 실제 거의 모든 신체 장기에 발생하는 것으로 알려져 있는데, 가장 흔한 부위인 위 외에도 폐, 갑상선, 침샘, 눈물샘에 발생하고, 드물게 안구, 유방, 방광, 신장, 흉선 등에도 보고된 바 있다. MALT 림프종은 오랜 기간동안 원격 전이하지 않고 국소 병변으로 남아 있는 특징이 있어 치료 방향 또한 국소 병변의 치료에 집중되며, 예후도 림프절 기원의 림프종에 비해 양호한 것으로 알려져 있다. 본 저자 등은 자궁 내막에 원발성으로 발생한 MALT 림프종 1예를 경험하였기에 문헌 고찰과 함께 이를 보고하고자 한다. Mucosa associated lymphoid tissue (MALT) lymphoma can rarely develop primarily in extranodal sites other than stomach which is the most common site for it. Other rare primary sites are small intestine, colorectum, esophagus, lung, thyroid, salivary gland, lacrymal gland, breast and skin. MALT lymphoma represents a distinct clinicopathologic features: it is usually localized to their original site for a long time and shows much more favorable prognosis than lymphoma at other site, but some MALT lymphoma can arise simultaneously or successively in different organ or give rise to another MALT lymphoma of other organ and can be multifocally disseminated or recurred. We report a very rare case of high grade B-cell lymphoma of mucosa associated lymphoid tissue (MALT) of the uterine endometrium, which was confirmed by immunohistochemical assay.

방광이행상피세포암에서 p53유전자의 변화

김법완,권태균,노기석,정성광,장세국,정운복,김정완 경북대학교 병원 1997 경북대학교병원의학연구소논문집 Vol.1 No.1

The objective of this study was to characterise the pattern of p53 mutations in bladder turmor. In this study, 25 bladder transitional cell carcinomas were analyed by immunohistochemistry (IHC) for p53 nuclear overexpression, and the results were compared with those of polymerase chain reaction-single strand conformational polymorphism (PCR-SSCP) analysis in exon 5-8 of the p53 gene and DNA sequencing analysis. 15 out of 20 cases (75%) showed p53 nuclear immunoreactivities on IHC. On PCR-SSCP analysis, 10 out of 25 cases(40%) had abnormal shifts on mobility. 62% of the mutations were in exon 8. Direct DNA sequencing analysis were performed in these 10 cases to confirm the presence of mutated p53 genes and to determine the type of mutations. Sixteen point mutations were detected in 10 cases. Tow specimens had double mutations and another two had triple mutations. G:C→A:T transitions were the most frequent patterns (62.5%). One mutation was a premature stop codon and two were silent mutations. There out of 10 had a point mutation at codon 285 (GAG/Glu→AAG/Lys) and two had at codon 280(GAG/Glu→AAG/Lys). One of 16 mutations was transition at hot spot codon 273 with CpG site. These results suggest that altered expressions and point mutations of p53 occured in all grade of bladder cancer, but are more associated with hight grade bladder tumors. To elucidate the carcinogenesis of bladder cancer, further studies should be carried out.

방식사의 유해물질 용출특성

김영철,이무강,나중균,박종원 慶星大學校 環境問題硏究所 1998 環境硏報 Vol.8 No.1

Extraction charaxteristics of hazardous components were investigated by anticorrosive sand. The hazardours components for anticorrosive sand were not exceeded limited level of groundwater quality. The COD concentration of waste-molding sand showed remarkable difference by molding factory, which was relatively high level. The quantity of corrosion for metalic pipe after lapse of ll month increased in the order of the following sample: sand>soils>waste molding sand. However, anticorrosive sand did not showed corrosion, it was observed that anticorrosive sand one of the the best material used for anticorrosive metalic pipe.

유기용매 추출법과 산가수분해에 의한 포플라의 전처리 및 효소당화액을 이용한 생물고분자의 생산에 관한 연구

김균성,박정극 동국대학교 산업기술대학원 1993 산업기술논문집 Vol.1 No.-

In this study the lignocellulosic biomass, Italy poplar, was pretreated by the chemical pretreatment method, i.e., organic solvent (Phenol/H_2O) extraction. Using Phenol/H_2O solvent system. Wood yield, % delignification and % sacchari-fication(72hours) of poplar after pretreatment at 190℃, 60 min. which was found out as the optimum pretreatment condition, were 46,3%, 96.1% and 83.35% (43.87 g/L) respectively. The possibility of reusing the spent organic solvent and recovery of hemicellulose fraction were also studied. By recycling spent black organic solvent in this process, we obtained an approximately identical results. The percent saccharification of 79.9% (43.6 g/L) was obtained from the recycled process and the degree of delignification was more than 99%. The delignification reactions using Phenol/H_2O solvent system showed two distinct mechanism of pseudo first order reactions (fast and slow), and the activation energy of the fast reaction was 38.4Kcal/gmol. For the recovery of hemicellulose fraction, poplar wood was pretreated using acid as a catalyst at high temperature and low concentration;180℃,0.05%∼0.15 vol% H_2SO_4(HTLC), and also at low temperature and high concentration;120℃,1∼4 vol% H_2SO_4(LTHC). 58% of hemicellulose was recovered whin the Italy poplar was pretreated at 180℃ with 0.1 vol% H_2SO_4 for 10 minutes (HTLC), and 74.4% recovery of hemicellulose fraction was obtained when it was pretreated at 120℃ with 4 vol% H_2SO_4 (LTHC) for 20 minutes, which is considered as an optimum condition for hemicellulose recovery. And after these acid hydrolysis followed by solvent extraction at 190℃, 60 min, the lower amount of sugar was obtained compared to one-step solvent extraction which was studied. As an application of saccharified broth, the culture of Zoogloea remigera 115 which produces biopolymer adsorbing heavy metals (Cu, Fe, Zn, Co etc) was conducted. When saccharified broth was used as a carbon source, the lag phase of the fermantation was longer than that of synthetic glucose media. After 60 hours of fermentation, the maximum cell density of 1.5 g/L was obtained. Final biopolymer concentration was 10.05 g/L after 200 hours of fermentation. Above experimental results showed the possibility of using saccharified broth as a carbon sourse for fermentation media.

Nd:YAG 레이저의 동작특성에 관한 연구 : 3단 병렬 순차 충·방전 방식 적용 3-mesh parallel sequence charge and discharge method

김희제,홍정환,김병균,박구렬,이동훈,김휘영 釜山大學校生産技術硏究所 1999 生産技術硏究所論文集 Vol.56 No.-

펄스형 Nd:YAG 레이저는 가공물질과 쉽게 반응하고, 램프에 의해서 연속발진은 물론 정상발진, Q-스이치 및 모드동기 발진까지 다양한 발진 형태가 가능하며 재료가공 및 계측용으로 널리 사용되어지고 있다. 재료가공에 있어서는 가공목적에 따라 에너지 밀도를 제어하는 것이 매우 중요하다. 에너지 밀도의 제어는 레이저 출력의 펄스반복률을 제어하는 방법이 주로 사용된다. 본 연구에서는 펄스형 Nd:YAG 레이저의 펄스반복률을 제어할 수 있는 3단 병렬 순차 충·방전 방식의 레이저 전원회로를 설계 및 제작하여 반복율에 따른 플래쉬램프의 전류파형 및 레이저 출력의 안정도와 신뢰성을 확인할 수 있었고, 펄스반복율은 30∼150[pps]까지, 30[pps]씩 증가시켰을 경우, 레이저 출력 효율은 약 5% 씩 감소한 반면, 축력은 약 4W 씩 증가하였다. A pulsed Nd:YAG laser interacts with processing materials easily, having different kinds of oscillators, such as CW by lamp, Q-switching, mode locking and so on. A pulsed Nd:YAG laser has been used in a wide variety of fields : measuring, materrial processing, and so on. In a material processing, it's very important to control an energy density according to the processing purpose. It is mainly used to control the energy density to vary pulse repetition rate. In this study, we designed and fabricated the 3-mesh parallel sequency charge and discharge circuit of which the pulse repetition was to be controlled. As increasing a repetition rate, we could find the stability and the reliability of laser output as well as flashlamp current waveform. When increasing a repetition rate from 30 to 150[pps] by 30[pps], we also found that the efficiency of lase output decreased by about 5%, while the output increased by about 4W.

달걀껍질(생, 삶은)의 수처리에 관한 연구

정대일,정선주,김인식,최영하,류정숙,이용균,최순규 동아대학교 환경문제연구소 1999 硏究報告 Vol.22 No.2

The selective absorption ability of low density heavy metal(Pb(Ⅱ) ion or Cu(Ⅱ) ion) of eggshell(raw or boiled) is better than one of existing absorption materials in treatment ability and experimental condition. The elimination ability of chlorine of eggshell(raw or soiled) is worse than one of active carbon. In elimination of trihalomethane, the effect of treatment of eggshell is almost the same as one of pine cones. And surface of eggshell(raw or boiled) after absorption of heavy metal ion was observed by Scanning Electron Microscope(SEM). Application and availability of eggshell(raw or boiled) as absorption material need lots of experiments. The experiment on baked eggshell is proceeding.

가축분뇨 비료성분 부하수준을 고려한 지역별 적정사육두수 설정

김재환,박치호,한정대,박백균 한국농업정책학회, 한국축산경영학회 2001 농업경영정책연구 Vol.28 No.2

In relation to pollution load, 166 towns and cities set the following optimum number of livestock, according to cultivated area, the amount of fertilizer ingredient for crops and wastes. According to the analysis of the total capacity for waste based on cultivated area and fertilizer requirement, N was 279,884 M/T, P2O5 140,464 M/T and K2O 182.559 M/T. Total amount of nutrient production according to the number of livestock were 222,331 M/T N, 64,716 M/T P2O5 and 86,670 M/T K2O, which are 86.7%, 53.6% and 52.7% of the fertilizer requirment. It is estimated that 45 regions showed an overload capacity of fertilizer per hectare in N, 11 regions in P2O5 and 13 regions in K2O, The converted optimum number of livestock was 13,415,000 Livestock Unit (LU).

체육〔무도〕관련학과 학생들의 대학생활에 대한 전망과 과제

김창모,진중의,장경태,김태균,김공 龍仁大學校 武道硏究所 2011 武道硏究所誌 Vol.22 No.1

이 연구에서는 체육․무도 관련학과 학생들을 대상으로 심층면접을 실시하여 이들의 대학생활에 대한 전반적인 문제점을 심층적으로 규명하는데 목적이 있다. 이러한 목적 달성을 위해서 전라남도 D대학교 체육관련 학과 학생들을 대상으로 비확률 표집방법 중 하나인 유목적 표집(purposeful sampling)에 의해 2학년부터 4학년까지 각 학년별 4명씩 총 12명으로 선정하였는데 다음과 같은 결론을 얻었다. 첫째, 체육․무도 관련학과 학생들의 대학생활에는 선․후배 간 체벌문화가 현재까지도 잠재되어 있음을 알 수 있었다. 이에 학생들은 선배들의 올바른 역할과 선․후배 간의 단합과 화합을 위한 매개체 요인이 필요하다는 의견을 보였다. 둘째, 체육․무도 관련학과와 같은 상․하 관계가 뚜렷한 집단에서는 선․후배간의 의사소통이 더욱 필요하지만 원활히 이루어지지 않는 것으로 나타났다. 또한 원활한 의사소통을 위해 다양한 개선을 요구하는 것으로 나타났다. 셋째, 체육․무도 관련학과 학생들은 대학생활에서 수업관련 문제점에 대해 가장 큰 비중을 두고 있었고 개선에 대한 욕구를 보였다. 특히 체육․무도 관련학과 전공수업에서는 무엇보다도 교수의 지도능력과 현실성 있는 교과과정 개설을 원하는 것으로 나타났다. 넷째, 체육관련 전공자들은 보편적으로 타 전공자들에 비해 취업의 기회 및 관련분야가 상대적으로 적을 수도 있다. 이러한 사회현실은 이들로 하여금 심리적인 불안을 갖게 하였으며 체육관련학과를 선택한 자체에 대한 불만족이기 보다는 체육․무도 관련 전공을 이수하고 나와서 안정적인 직장으로 연결되지 못하는 사회 제반적 여건에 대한 문제점을 보였다. 따라서 체육․무도 관련학과 학생들은 취업관심분야에 대한 업무능력․관련지식 등의 자질과 조건을 갖추기 위해 큰 관심을 가지고 있다. 취업정보 및 자격증 취득 등 취업을 위한 사전준비도 철저히 하고 있는 것으로 나타났다.

반복가열냉각에 의한 수화시멘트 페이스트와 골재 분리 방법

김세훈,임승준,안재철,오상균,김정길 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2(구조계)

Cement mortar and efficient disconnection of aggregate are indispensable for recycling of waste concrete, and the problem is with quality in the existing physical disconnection way, and the problem has been by application of a concrete recycling construction materials. Specially, in case of recycled aggregate, the quality is lowered because of the fine aggregate powder which has a bad influence on flowability, a compression strength by adhesion of mortar on the aggregate face, and the case of recycled cement was added to during recycle cement. Therefore, a mortar and interfacial separation of aggregate are large in proper quality for concrete recycling is expected that affect. This study based on the recycled cement manufacturing way which used an aggregate interfacial separation of waste mortar in this study so that the coefficient of thermal expansion of hardend cement paste and an the coefficient of thermal expansion of a fine aggregate are different in a recycled cement manufacturing way, but leaves a purpose.