간세포암과 감별이 어려웠던 악성중피종 치험 1예

김선문,허원석,채경훈,강윤세,정재훈,김연수,박기오,문희석,이엄석,김석현,성재규,이병석,이헌영,신경숙,조준식,송인상,강대영 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

Malignant peritoneal mesothelioma is a rare neoplasm that arises from the mesothelium of a serosal cavity and is a rapidly fatal disease with a median survival of 4 to 12 months for untreated cases. Recently, we experienced a case with malignant peritoneal mesothelioma who was suspected hepatocelluar carcioma by abdominal CT scan and was confirmed by biopsy including immunohistochemical stain(calretinin) after surgery. We performed tumor excisions and wedge resection of the liver(segment Ⅷ)and inserted Tencoff catheter in abdominal cavity at 25th day of post-operation. We treated with intraperitoneal paclitaxel(25mg/m^(2)/day for 5 days) six courses monthly. She was well tolerable and is still living without any evidence of recurrence for 14th month of post-operation.

유리섬유보강 폴리머 복합패널의 피로특성 : Fatigue Properties of Glass Fiber Reinforced Polymer Composite Panel

연규석,정중호,권택정,김성기 강원대학교 부설 석재복합신소재 제품연구센터 2004 석재연 논문집 Vol.9 No.-

본 연구는 압축강도 1,020 kgf/㎠를 갖는 폴리머 모르타르를 중심부로 하고 내·외표면은 고인장의 GF RP로 보강된 샌드위치 패널의 피로 특성에 관한 연구이다. 이를 위해 중심부 폴리머 모르타르와 압축 및 인장측 GERP보강층 두께를 달리하는 샌드위치 형식의 패널 시험체를 제작하고 이에 대한 휨 피로 시험을 수행함으로써 폴리머 모르타르 두께와 GFRP보강층 두께가 패널의 휨피로거동에 미치는 영향 즉 피로하중수준-피로수명과의 상관관계를 구명하였다. 실험결과 하중수준이 증가함에 폴리머 모르타르 및 GFRP 보강두께에 관계없이 샌드위치 패널의 피로수명은 감소하는 경향을 나타냈고, 동일 하중수준에서는 폴리머 모르타르 두께가 증가함에 따라 피로수명은 감소하는 경향을 나타냈으며, GFRP 보강층 두께가 증가함에 따라 피로수명이 증가하는 경향을 나타냈다. 한편 이러한 폴리머 모르타르 및 GFRP 보강층 두께에 따른 피로응력수준-피로수명 상관관계는 수정된 Miner의 법칙과 부합됨을 확인 할 수 있었다. Is this study, the fatigue properties of the sandwich panel of which core was made of the polymer mortar and inner and outer facings were reinforced by a high-tensile GFRP were surveyed. Sandwich-panel specimens consisted of polymer mortar core and GFRP compressive and tensile sides with various thickness were produced for the experimental study. Flexural fatigue tests were conducted to figure out the correlation between fatigue load and fatigue life for various thickness of core and facings, and its results are presented. The correlation obtained in this study between fatigue load and fatigue life for various thickness are in good agreement with the modified Miner's law.

거푸집 개발용 GFRP보강 폴리머 복합패널의 휨 특성

연규석,권택정,정중호,김성기 강원대학교 부설 석재복합신소재 제품연구센터 2004 석재연 논문집 Vol.9 No.-

본 연구는 반영구수명의 교량상판용 영구거푸집을 개발할 목적으로 리브를 갖는 GFRP보강 폴리머 콘크리트 복합패널을 제작하고 이에 대한 휨특성을 고찰한 것이다. 연구에서 리브높이와 인장측 GFRP보강층 두께를 달리하는 12종류의 GFRP보강 폴리머 콘크리트 복합패널 시험체를 제작하고 이에 대한 휨시험을 수행함으로써 리브 높이와 GFRP보강층 두께가 복합패널의 휨특성에 미치는 영향을 실험적으로 구명하였다. 시험결과 GFRP보강 폴리머 콘크리트 복합패널의 극한 모멘트는 GFRP 보강두께가 증가 1.0에서 4.0 mm로 증가 할때, 리브 높이에 관계없이 약 93~101%의 거의 일정한 중가폭을 보였고, 리브 높이가 1.0에서 3.0cm로 증가할 때, GFRP 보강층 두께에 관계없이 약 35~41%의 거의 일정한 증가폭을 보였다. 또한 강도설계법에 기초한 극한모멘트 예측식은 실험결과와 잘 부합되어 리브를 갖는 GFRP 보강 폴리머 콘크리트 복합패널을 영구거푸집에 적용할 시 지간에 따른 상용 단면설계에 매우 유용하게 적용될 것이다. In this study, twelve different GFRP-reinforced polymer concrete composite panel specimens with various rib heights and tensile side and reinforced side thickness were produced. flexural tests were conducted to figure out the effect of the height and thickness influencing on the flexural properties of composite panel. Test results of the study are presented. Especially, a prediction equation of the ultimate moment based on the strength design method agrees well with the test results, and it is thought to be useful for the corresponding design of cross-section according to various spans as the GFRP-reinforced polymer concrete composite panel is applied for a permanent form.

SJO¨GREN'S SYNDROME 환자에게 즉시 임프란트 술식을 행한 치험례

최정환,손동석,이지연,이윤서,안선희,이재목 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.5

The old edentulous patients experience xerostomia commonly. They have considerable difficulty in wearing tissue-supported prosthesis and high risk rate of caries. One of them is Sj□gren's syndrome patient. Sj□gren's syndrome is a chronic inflammatory autoimmune disorder that results in a lymphocyte-mediated destruction of exocrine glands. We planned to place implants immediately after extraction in this case of autoimmune disease. The advantages of immediate implant placement include considerable decrease in time from tooth extraction to placement of the final prosthesis, fewer surgical procedures, and better acceptance of the overall treatment plan. We present a case of Sj□gren's syndrome patient treated with immediate implant placement & immediate loading in anterior region and immediate implant placement in posterior region.

청소년기 문제행동과 부모 양육행동에 관한 연구

손석한,노경선,허묘연,정현옥,이소희,김세주 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.4

연구목적 : 일반 청소년의 문제행동(내재화 문제, 외현화 문제)을 평가하고, 그들을 정상 집단과 문제행동 집단으로 나누어 집단간에 부모 각각의 양육행동이 어떠한 차이를 보이는지 알아보고자 한다. 방 법 : 서울 소재의 일반 고등학교 학생 792명을 대상으로 부모 양육행동 척도와 K-YSR을 실시하여 청소년이 지각하는 부모의 양육행동과 청소년의 문제행동을 평가하였다. 부모의 양육행동과 청소년의 문제행동과의 상관관계를 분석하였다. 학생들이 보고한 각 문제행동을 상/하위 25% tile을 기준으로 정상 집단과 문제행동 집단으로 나누어 부모의 양육행도의 차이를 분석하였다. 결 과 : 다음과 같다. 1) 부모의 애정, 합리적 설명, 감독의 긍정적인 양육행동은 대부분의 청소년 문제행동들과 유의한 부적 상관을 보였다. 반면에 학대, 과잉간섭, 과잉기대, 방임, 비일관성이 부정적인 양육행동은 문제행동들과 유의한 정적 상관이 있었다. 2)내재화 문제를 보이는 청소년들은 정상 집단에 비해 부모로부터 학대, 과잉간섭, 과잉기대, 방임, 비일관성의 양육행동을 유의하게 더 많이 받았고, 반면에 애정을 유의하게 더 적게 받았다고 지각하고 있었다. 외현화문제를 보이는 청소년들은 정상집단의 청소년들에 비해 부모로부터 학대, 과잉간섭, 과잉기대, 방임, 비일관성의 양육행동을 유의하게 더 많이 받았고, 반면에 감독을 유의하게 더 적게 받았다고 지각하고 있었다. 3) 내재화 및 외현화 문제를 모두 보이는 집단이 내재화 문제만 보이는 집단과 외현화 문제만 보이는 집단에 비해서 양쪽 부모로부터 유의하게 더 많은 과잉간섭을 받을 것으로 지각하고 있었다. 또한, 내재화-외현화 집단과 내재화 집단은 외현화 집단에 비해서 어머니로부터 유의하게 더 적은 애정과 더 많은 방임을 받고 있고, 아버지로부터 유의하게 더 많은 학대를 받은 것으로 지각하고 있었다. 결 론 : 이상의 결과로 미루어 볼 때, 청소녕이 지각한 부모의 학대, 과잉간섭, 과잉기대, 방임, 비일관성의 양육행동은 청소년의 내재화 및 외현화 문제 모두와 유의한 연관이 있고, 반면에 부모의 애정, 감독, 합리적 설명의 양육행동은 다양한 청소년기 문제행동을 줄일 수 있음을 시사하고 있다. Objectives : The purpose of this study is to evaluate the problem behaviors of adolescents and to discriminate between parenting behaviors of problem behavior groups and those of non-problem behavior group. Methods : The subjects of this study were 792 high school students in Seoul. We administered 'parenting behavior Inventory' and Korean version of Youth Self-Report(K-YSR) to the subjects in order to evaluate the parenting behaviors perceived by adolescents and the problem behaviors of adolescents. We analzed the relationship between parenting behaviors and problem behaviors. We classified the subjects into problem behavior groups(internalizing group, externalizing group, internalizing-externalizing group) and a non-problem behavior(normal) group. We studied the differences of parenting behaviors among the groups. Results : The results are as follows. 1) There were significant negative correlations between the positive parenting behaviors such as affection, reasoning, and monitoring and the problem behaviors of adolescents. By contrast, there were significant positive correlations between the negative parenting behaviors such as physical abuse, intrusiveness, over-expectation, neglect, and inconsistency and the problem behaviors of adolescents. 2) Adolescents of the internalizing group perceived significantly more parental abuse, intrusiveness, over-expectation, neglect, and inconsistency than those of normal group. Meanwhile, they perceived significantly less affection than normal adolescents. Adolescents of the externalizing group also perceived significantly more parental abuse, intrusiveness, over-expectation, neglect, and inconsistency than those of normal group. Also, they perceived significantly less monitoring than normal adolescents. 3) Adolescents of the internalizing-externalizing group perceived significantly more intrusiveness from both parents than those of either the internalizing or the externalizing groups. Adolescents of the internalizing-externalizing group perceived significantly less affection and more neglect from their mothers than those of the internalizing of the externalizing groups. In addition, adolescents of the internalizing-externalizing group perceived significantly more physical abuse from their fathers than those of the internalizing or the externalizing groups. Conclusion : Parenting behaviors such as abuse, intrusiveness, over-expectation, neglect, and inconsistency are associated with both internalizing and externalizing problems. In contrast, our results suggest that parenting behaviors such as affection, monitoring, and reasoning might decrease the various problem behaviors of adolescents.

전자서명을 통한 인증기술과 공개키 기반구조에 대한 고찰

황재훈,박춘석,정연식,송홍엽 연세대학교 산업기술연구소 2000 논문집 Vol.32 No.2

전자서명과 인증의 정의 및 필요성과 개략적인 기술적 요소 등을 정리하고, 정보보호시스템의 보안에 대한 신뢰도를 향상시킬 수 있는 방향을 제안한다. 공개키의 인증문제를 해결하기 위해 발전된 공개키 기반구조, 즉 PKI에 대해서 살펴봄으로써 인증에 대한 심층적 고찰을 수행한다.

Inoue Balloon을 이용한 PMV의 장·단기 결과 분석

진은선,이연아,전숙,김현숙,정승묵,박상선,최락경,임달수,홍석근,황흥곤 대한순환기학회 2003 Korean Circulation Journal Vol.33 No.11

사망진단서(사체검안서) 상의 선행사인으로부터 사망통계의 원사인이 선정되는 비율 : 3개 대학병원에서 교부된 사망진단서를 중심으로

박우성,박석건,정철원,김우철,탁우택,김부연,서순원,김광환,서진숙,부유경 한국의료QA학회 2004 한국의료질향상학회지 Vol.11 No.1

Background : To exatnine the problems intolved in writing practice of death certificates, we cotnpated the determination of underlying cause of death for wital statistics using recorded underlying cause of death in issued death statistics. Methods : We collected 688 rnortality certificates issue in year of 2,000 from 3 university hospitals. And we also collected vital statistics from ministry of statistics. The causes of death were coded by experienced medical record wpecialists. And causes of death determined at ministry of statistics for national vita statistics were mapped to causes of death recorded at each death certificates. The rate that underlying causes of death for vital statistics were derived from underlying causes of death recorded at issued death certificaties sere analysed. Results : 64.5% of underlying cause of death for could be derived from underlying cause of death recorded at issued death certificates, 8.6% derived from intermediate cause of death, and 3.9% derived from direct cause of death. In 23% of cases, underlying cause of death could not be derived using issued death certificates. The rate that underlying cause of death for vital statistics could be derived from underlying cause of death recorded at death certificates was different between 3 university hospitals. Ane the rate was also different between death certificates and postmortem certificates. We classified the causes of death using 21 major categories. The rate was different between diseases or conditions tha caused death too. Conclusion : When we examined the correctness of death certificate writing practice using abpve methods, cortectness of writing could not be told as satisfactory. There was difference in correctness of writing between hospotals, between death certificates and postmortem certificates, and between diseases and conditions that caused death. With this results, we suggested some strategy to improve the correctness of death certificate writing practice.

동일한 시료에 대한 국내 기관간의 STR 분석결과 비교 : STR 유전자좌 분석법의 표준화 설정을 위하여

박종태,신경진,양윤석,우광만,이숭덕,이승환,이정빈,정연보,조승희,한길로,한면수,홍승범 大韓法醫學會 2001 대한법의학회지 Vol.25 No.1

This paper described a collaborative exercise intended to see what kinds of short tandem repeat (STR) loci are used in different DNA typing laboratories in Korea and to compare their results for the demonstration whether uniformity of DNA profiling results from different laboratory could be achieved in Korea Laboratories were asked to test five tissue DNAs using methods routinely used in each laboratory and to report the results to the coordinating laboratory. The exercise demonstrated that each laboratory was using different STR loci for the typing with different STR numbers,2 VNTRS,36 STRs and amelogenin in total, and the direct comparison of the results from all the laboratory for the 18 loci could not be done as only one laboratory submitted typing results. Among 21 loci for which several laboratories submitted typing results, results for 14 loci were the same and results for the other 7 loci were different depending on the participating laboratory. D1S80, F13A01, D16S539, D21S11, D18S51, D3S1744 were the loci with different typing results. Even in the cases where commercial kits were used, the results were not the same depending on the machines used, that is the capillary electrophoresis or the gel based electrophoresis. The reason for the different results, points about the standardization of the methods arid the profiling data were described.

한국산 녹차 5종의 물의 온도 및 우린 횟수별에 따른 Chlorphyll 함량의 변화

변재옥,최석현,小机信行,이연정,김동석,한재숙 동아시아식생활학회 2004 동아시아식생활학회지 Vol.14 No.2

This study was carried out to examine the changes of chlorophyll a and b contents by the extraction temperatures and the number of soaking using five kinds of Korean green teas(3 kinds of green tea and 2 kinds of tea bag) which were obtained from a local market in Daegu city, Korea. The chlorophylls were extracted with 80% acetone, and determined by a visible spectrophotometer. The concentration of chlorophyll in Sulrok(tea bag) were the highest among all kinds of teas when they were extracted at 60, and decreased with the number of soaking increased. On the other hand, the chlorophyll content of green teas was the highest at 80, and decreased with the increase of the number of soaking as the tea bag did. It was found that the Korean tea bag contained more chlorophyll than green teas did, and green teas contained significantly more chlorophyll b than chlorophyll a.