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        Integrated interpretation of geophysical data from Zagros mountain belt (Iran)

        Mansoure Montahaei,Pilar Queralt,Juanjo Ledo,Behrooz Oskooi,Josep A. Muñoz,Alex Marcuello 한국지질과학협의회 2021 Geosciences Journal Vol.25 No.3

        Fluid composition and distribution, the key factors determining geoelectric structure in a seismically active region, are controlled by local and regional stresses and rheological contrasts. Two closely located magnetotelluric and seismic velocity profiles are jointly interpreted to recover more accurately the structural boundaries and fluid distribution within the crust in the central Zagros collision zone, one of the world’s most seismically active mountain belt. A multi-site and multi-frequency approach was used for the strike analysis of regional structure and decomposition of distortion effects on magnetotelluric data. Distortion corrected magnetotelluric data were then used for two-dimensional inversion modeling. The results indicate distinct conductive structures within the crust: (i) a thick conductive overburden in the southwest of the profile, (ii) high conductivities attributed to the fault zone conductors (FZCs) and (iii) an almost concave conductor extending from middle to lower crust in the central–eastern portion of the mountain belt, beneath the High Zagros (HZ). Comparison with the already available S-wave velocity structure, obtained by joint inversion of P-wave receiver functions and surface wave dispersion data shows that these main conductive features are spatially correlated with a low-velocity layer representative of the sedimentary cover overlying the Arabian platform and a velocity contrast bounded by the main Zagros thrust (MZT) fault, indicating the presence of fault zone fluids. The joint interpretation of magnetotelluric inverse modeling and seismicity data also shed light on fluid generation influencing rock deformation and seismicity in this region. It suggests that beneath the HZ, deep crustal fluids generated through metamorphism may promote aseismic deformations before high stresses are builtup and cause the north-eastern part of the Zagros Fold and Thrust Belt (ZFTB) to be seismically inactive compared to its southwestern part.

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        Effect of Magnet Implant on Iron Biodistribution of Fe@C Nanoparticles in the Mouse

        Elvira Escribano,Rodrigo Fernández-Pacheco,J. Gabriel Valdivia,M. Ricardo Ibarra,Clara Marquina,Josep Queralt 대한약학회 2012 Archives of Pharmacal Research Vol.35 No.1

        The in vivo biodistribution of Fe@C nanoparticles (NP) was tested in mice bearing an inflammatory focus induced by injecting carrageenan into an air pouch previously formed on their back. The animals were intravenously injected NP with a high (60 mg/kg) or a low iron dose (6 mg/kg) and sacrificed 2 h later. Blood and organ samples (liver, spleen, lung, and kidney)were obtained; washed exudates were also collected. Iron concentration in plasma, blood cells, organs, and exudates was determined by flameless atomic-absorption-spectroscopy after digestion of organic material. Pouch exudate volume increased in all groups of mice with experimental inflammation. After i.v. administration of the high and low dose of NP,iron in exudate increased by 83.3% and 92.2%, respectively. A similar increase in hepatic iron appeared after the high dose (78%), but no increase appeared after the low dose. When the magnet was present, a 157% and 119% increase of iron in exudate appeared after both doses of NPs, but only the high dose of NP increased iron liver (60%). The presence of a magnetic field in the pouch favored selective biodistribution of NP in the inflammatory focus. These results indicate that mice with an inflammatory compartment are suitable for primary screening of different NP types. They also show that selective biodistribution is greater when a low dose of NP was used and that distribution in the target organ was increased by the magnetic field.

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