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- 저자 : José Rodellar (검색결과 2 건)
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Interstory-interbuilding actuation schemes for seismic protection of adjacent identical buildings
Francisco Palacios-Quiñonero,Josep Rubió-Massegú,Josep M. Rossell,José Rodellar 국제구조공학회 2019 Smart Structures and Systems, An International Jou Vol.24 No.1
Rows of closely adjacent buildings with similar dynamic characteristics are common building arrangements in residential areas. In this paper, we present a vibration control strategy for the seismic protection of this kind of multibuilding systems. The proposed approach uses an advanced Linear Matrix Inequality (LMI) computational procedure to carry out the integrated design of distributed multiactuation schemes that combine interbuilding linking devices with interstory actuators implemented at different levels of the buildings. The controller designs are formulated as static output-feedback H-infinity control problems that include the interstory drifts, interbuilding approachings and control efforts as controlled-output variables. The advantages of the LMI computational procedure are also exploited to design a fully-decentralized velocity-feedback controller, which can define a passive control system with high-performance characteristics. The main ideas are presented by means of a system of three adjacent five-story identical buildings, and a proper set of numerical simulations are conducted to demonstrate the behavior of the different control configurations. The obtained results indicate that interstory-interbuilding multiactuation schemes can be used to design effective vibration control systems for adjacent buildings with similar dynamic characteristics. Specifically, this kind of control systems is able to mitigate the vibrational response of the individual buildings while maintaining reduced levels of pounding risk.
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Laura Barrachina,Ana Rosa Remacha,Antonio Romero,Francisco José Vázquez,Jorge Albareda,Marta Prades,Beatriz Ranera,Pilar Zaragoza,Inmaculada Martín-Burriel,Clementina Rodellar 대한수의학회 2017 Journal of Veterinary Science Vol.18 No.1
Mesenchymal stem cells (MSCs) are gaining relevance for treating equine joint injuries because of their ability to limit inflammation and stimulate regeneration. Because inflammation activates MSC immunoregulatory function, proinflammatory priming could improve MSC efficacy. However, inflammatory molecules present in synovial fluid or added to the culture medium might have deleterious effects on MSCs. Therefore, this study was conducted to investigate the effects of inflammatory synovial fluid and proinflammatory cytokines priming on viability and plasticity of equine MSCs. Equine bone marrow derived MSCs (eBM-MSCs) from three animals were cultured for 72 h in media supplemented with: 20% inflammatory synovial fluid (SF); 50 ng/mL IFN-g and TNF-a (CK50); and 20 ng/mL IFN-g and TNF-a (CK20). Proliferation assay and expression of proliferation and apoptosis-related genes showed that SF exposed-eBM-MSCs maintained their viability, whereas the viability of CK primed-eBM-MSCs was significantly impaired. Tri-lineage differentiation assay revealed that exposure to inflammatory synovial fluid did not alter eBM-MSCs differentiation potential; however, eBM-MSCs primed with cytokines did not display osteogenic, adipogenic or chondrogenic phenotype. The inflammatory synovial environment is well tolerated by eBM-MSCs, whereas cytokine priming negatively affects the viability and differentiation abilities of eBM-MSCs, which might limit their in vivo efficacy.
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