만성골반통의 동서의학적 고찰 : 부인과 질환으로 중심으로

김순열 ( Soon Yeol Kim ),윤종원 ( Jong Won Yoon ) 동국대학교 한의학연구소 1996 東國韓醫學硏究所論文集 Vol.5 No.-

The purpose of this study was to generalize the conception of chronic pelvic pain(CPP)through the literature of oriental medicine and occidental medicine. The results are obtained as follows. First, chronic pelvic pain(pain of more than 6 months' duration) may include pain of gynecologic, gastroenterologic, urologic neurologic, and musculoskejetal origin. In this study, the etiologic of chronic pelvic pain may remain obscure and the relationship between certain types of pathologic, such as endometriosis or adhesions, and the pain response may be inconsistent and often inexplicable. Second, the causes of CPP through the literature of oriental medicine were reviewed as pains due to a wind-pathogen, a cold, disorder of Qi, disorder of blood stasis, a improper diet, disorder of fluid, and deficiency type etc... And the charateristic pains were concerned with a aching pain, a heavy pain, a distending pain, a pain due to mass in the abdoman, a pain likes pulling etc... The degree an4 classification of charateristic pains in current of time were dependent on subjective factors. Third, in oriental medicine, it wasn`t to be suggested concretely recognition of etiological factor in pain, But they recognised that facters were influenced by pain. For example, diretic peripheral demages were concerned with a blood stasis, a phlegm, a damp phlegm, heart, and the pains that were occurrenced by sevn emotions were concerned with a stagnancy of Qi or a stagnancy of liver-Qi.

현행 중등학교 과학 실험 , 실습 교육 실태 조사 및 그 운영 진단 (Ⅱ) : 고등학교 과학 실험 , 실습 교육을 중심으로

김영호,이윤종,정원우,강용희,양승영,윤성효,안병호,윤일희,권용주,임성규,오철한,기우항,전명남,김중욱 한국과학교육학회 1998 한국과학교육학회지 Vol.18 No.3

본 연구는 96년도에 실시한 우리 나라 중학교 과학 실험·실습 교육의 실태 조사 연구에 따른 계속 연구의 일환으로 고등학교 과학 실험·실습 교육의 실태를 조사하기 위한 것이다. 연구내용은 고등학교 과학 교과서의 분석, 실험·실습 실시 현황 분석, 현행 실험·실습 교육의 문제점 분석, 현행 학교 구성원들의 실험·실습 교육 운영 실태 조사 및 현행 실험·실습 교육의 개선을 위한 연구과제 도출을 주요 연구내용으로 다루었다. 연구방법은 전국의 고등학교 80개교를 대상으로 이들 학교의 학생 1,977명, 교사 165명, 학교장 80명에게 적용하였다. 본 연구에서 밝혀진 결과를 중심으로 우리 나라 고등학교 과학 실험 실습 교육의 정상화를 위한 실험 내적인 연구과제를 제시하면 다음과 같다. (1)교재 개발에 대한 연구, (2)실험 킷트 개발에 대한 연구, (3)교사교육 및 재교육 프로그램 개발에 대한 연구, (4)교실 밖 실험·실습 활동 프로그램 개발에 대한 연구, (5)과학 실험·실습 소재의 개발에 대한 연구. This study was accomplished to analysis and survey on the experimental and practical science education of high school in korea for the consecutive study of the an analysis and survey on the experimental and practical science education of middle school in korea(Lee, Yoon-Jong et al., 1997). The status of facilities, management for the experiment, practices, teaching methods in high schools have been investigated. The present status and reasonable management of the high school science education have been grasped from the questionaires. To do this 165 high school science teachers, 1977 students and 80 principals of high schools in Korea are administered questionaires of Science Education Research Institute of Kyungpook National University(1997). The results of this study are as follows : The reasonable management for experiments and practices of science education were scanty in the high school around the urban and rural school owing to the shortage of facilities and equipments, crowded class, excessive class works for teacher, excessive contents of present textbooks and insufficiency of the administrative supports etc. The current teaching method of high school science has emphasized knowledge. This fact does not satisfy the objective of learning due to lack of the teaching method. Desirable directions for the improvement of present status of high school science education were proposed in this paper.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

5052 및 6061 알루미늄 합금 레이저 용접에 관한 연구

윤종원,이윤상 東義大學校産業技術開發硏究所 2003 産業技術硏究誌 Vol.17 No.-

두께 2㎜ 압연판재 알루미늄 합금 5052 및 6061 Nd:YAG 레이저 용접부의 인장특성 및 액압성형성을 조사하였다. 6061의 경우 5052에 비해 레이저 용접부의 기계적 특성 열화가 현저한 것으로 조사되었다. 모든 cross-weld 인장시험편 및 액압성형시험 시편에서 용접금속을 따라 파단이 일어났으며 파단면에는 기공이 관찰되었다. 특히 6061 용접금속에서 관찰되는 고온균열은 6061 용접부의 현저하게 저하된 인장강도, 연신률, 성형성의 주요한 원인으로 추정된다.

6K21-T4 알루미늄 합금 레이저 용접부의 기계적 성질에 미치는 필러 와이어의 영향

윤종원,강준일 동의대학교 산업기술개발연구소 2006 産業技術硏究誌 Vol.20 No.-

6xxx(Al-Mg-Si) alloy is candidate material for eco-friendly car (lightweight car body structure and panels) due to their good combination of strength and formability. 6K21 aluminum alloy sheet of 1㎜ and 2㎜ thickness were TB(tailored blank) welded using continuous wave Nd:YAG laser with and without 4043 filler wire. The effect of filler wire on the weldability of 6K21 alloy was investigated. The weld metal composition was changed by feeding the 4043 filler wire containing 5wt.% Si. Solidification cracking in the weld metal was substantially reduced when the filler wire was used. Tensile strength and formability of the welds were improved compared to those of welds made without filler wires. It was revealed by EPMA analysis and image mapping that the abundant amount of Al-Si eutectic existed particularly at the interdendritic sites or grain boundaries and thus the eutectic prevented the solidification cracking in the weld metal.

상아질 결합제가 컴포머의 불소유리에 미치는 영향에 관한 연구

윤여상,김종수,권순원,김용기 대한소아치과학회 2001 大韓小兒齒科學會誌 Vol.28 No.2

본 연구의 목적은 와동 충전시 충전재와 지질 사이에 개재되는 상아질 결합제가, 수복물에서 유리되는 불소가 와동 벽으로 침투하는 과정에 어떠한 영향을 주는지를 조사함이었고, 부가적으로 레진 강화형-글라스 아이오노머 시멘트의 접착에도 상아질 결합제를 도포하는 것이 체질과의 결합력을 강화시킬 수 있는지에 대해 평가하고자 하였다. Fuji II LCR와 Dyract APR를 선정하여 상아질 결합제의 도포 여부에 따른 불소 유리량 측정과 전단 결합 강도도를 비교분석하였으며, 치질 내로의 불소 침투 양상은 교환 시기에 있는 재2유구지에 Fuji II LCR와 Dyract APR를 충전하고 3주내에 발거하여 EPMA필 분석하였다. 상아질 결합제는 불소 유리량을 현저하게 감소시키는 것으로 나타났으며(p<0.05) Fuji II LCR의 경우 상아질 결합제의 도포가 결합강도를 증가시키지 못하였다. EPMA분석결과 상아질 결합제는 충전재로부터 유리되어 나오는 불소가 치질 내로 확산되는 것을 방해하는 것으로 확인되었다. It is well known that glass-ionomer cement and compomer can release fluoride which can inhibit the progresion of dental caries. The purposes of thins study were to evaluate whether the fluoride from fluoride-containing ailing materials can penetrate the dentin bonding adhesive and the dentin bonding adhesive can increase the bond strength of resin-modified glass lonomer. The amount of fluoride release from resin-modified glass lonomer and compomer was measured during 28 days of period find statistically analyzed by t-test. The bond strength of each material with/without dentin bonding adhesive was measured and also statistically analyzed by t-test. The distribution of fluoride from each material into the tooth was explored by electron probe microanalysis system (EPMA). The expenmental teeth used were second primary molars about to exfoliate. The amount of fluoride from each material was diminished by dentin bonding adhesive during 28 days(p<0.05) and the bond strength was not increased by dentin adhesive in resin-modified glass ionomer. The bond strength of group VI was not detectable. The distribution of fluoride from earth material into teeth was according to dentino-enamel junction and dispersed into pulp from pulpal floor. The widest distribution was shown in resin-modified glass ionomer cement filled without the application of dentin bonding adhesive.

Capsaicin이 동통억제효과를 나타내는 기전에 관한 연구

이종은,김봉옥,이원택,윤호,박경아 대한해부학회 1995 Anatomy & Cell Biology Vol.28 No.5

기업의 부채구조결정과 기업특성간의 관계에 관한 연구

윤봉한,원종철 中央大學校經營硏究所 2003 經營學論集 Vol.29 No.2

Hibiscus Syriacus L品種改良에 關한 基礎 硏究

元鍾樂,鄭玧洙 동국대학교 농림과학연구소 1980 農林科學 論文集 Vol.6 No.-

In order to obtain the basic information for the mutation of Hibiscus syriacus L., the seeds and plants were created with gamma-ray from Co-60 source. LD_50 on germination of irradiated seeds was about 10KR. The rate of chlorophyll reficient mutation was about 13% and 1% on seed and plant irradiation, dwarf type mutation rate being 0.5%. Most of all the chlorophyll mutation was induced with chimera on part of branch and node position of plant. Mutations at different parts of irradiated plant were largely formed upper and low part in V_1 and V_2 branch. The upper part buds of V_1 branch in irradiated plant were more multi-cellular than middle and low part, and primordium cell of V_2 branch bud seemed to be differentiated from V_1 branch, being multi-cellular condition in low part bud than upper and middle part of V_2. The dwarf type selected were characterized on 25% shortening than noncreated plant and half in number of node.

직접 분사식 과급 디이젤엔진의 분사계에 대한 성능특성 연구

윤준규,이종원 경희대학교 산학협력기술연구원 1995 산학협력기술연구논문집 Vol.1 No.-

The influences of fuel injection system on performance of a T/C DI diesel engine were studied in this paper. Fuel injection system is an important system in the exhaust emission and performance of a diesel engine. Effect of fuel injection system in a diesel engine combustion was studied experimantally by measuring the performance and analyzing the combustion phenomena in a T/C DI diesel engine. The selected injection parameters were nozzle hole diameter, number of nozzle spring, nozzle cone angle. From the measured results, It is shown that a small nozzle hole diameter and 1 stage spring holder have the advantage of increasing the engine performance and exhaust emission except of a low speed range. According to this study, I knew that it needs to much more investigation in order to improve for the optimum combustion system.