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Active vibration control based on modal controller considering structure-actuator interaction
Jinjun Jiang,Weijin Gao,Liang Wang,Zhaohua Teng,Yongguang Liu 대한기계학회 2018 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.32 No.8
Active vibration control to suppress structural vibration of the flexible structure is investigated based on a new control strategy considering structure-actuator interaction. The experimental system consists of a clamped-free rectangular plate, a controller based on modal control switching, and a magnetostrictive actuator utilized for suppressing the vibrations induced by external excitation. For the flexible structure, its deformation caused by the external actuator will affect the active control effect. Thus interaction between structure and actuator is considered, and the interaction model based on magnetomechanical coupling is incorporated into the control system. Vibration reduction strategy has been performed resorting to the actuator in optimal position to suppress the specified modes using LQR (linear quadratic regulator) based on modal control switching. The experimental results demonstrate the effectiveness of the proposed methodology. Considering structure-actuator interaction (SAI) is a key procedure in controller design especially for flexible structures.
Xiaoming Deng,Zhengyu Jiang,Changli Wang,Na Li,Lulong Bo,Yanping Zha,Jinjun Bian,Yan Zhang,Mengda Xu 생화학분자생물학회 2019 Experimental and molecular medicine Vol.51 No.-
Acetate has been indicated to be elevated and to regulate inflammation in inflammatory and metabolic diseases. The inflammasome serves as a key component of immune homeostasis, and its dysregulation can lead to various inflammatory disorders. However, little is known about the effects of acetate on inflammasome activation and the underlying mechanism. Here, we demonstrate that acetate attenuates inflammasome activation via GPR43 in a Ca2+-dependent manner. Through binding to GPR43, acetate activates the Gq/11 subunit and subsequent phospholipase C-IP3 signaling to decrease Ca2+ mobilization. In addition, acetate activates soluble adenylyl cyclase (sAC), promotes NLRP3 inflammasome ubiquitination by PKA, and ultimately induces NLRP3 degradation through autophagy. In vivo, acetate protects mice from NLRP3 inflammasome-dependent peritonitis and LPS-induced endotoxemia. Collectively, our research demonstrates that acetate regulates the NLRP3 inflammasome via GPR43 and Ca2+-dependent mechanisms, which reveals the mechanism of metabolite-mediated NLRP3 inflammasome attenuation and highlights acetate as a possible therapeutic strategy for NLRP3 inflammasome-related diseases.
Xinglong Xie,Yu Qiu,Sen Zhao,Hai-Ying Jiang,Jinjun Lu 한국화학공학회 2018 Korean Journal of Chemical Engineering Vol.35 No.10
We recently reported that PhC2Cu nanobelt exhibits excellent photocatalytic degradation of organic pollutants and activation of molecular O2. However, there has been no further research about the relationship between its crystal structure and photocatalytic activity. Herein, a new safe and energy-save method, photo-synthesis, to prepare PhC2Cu nanobelts with preferential active exposure facet was developed. It was used to study the relationship between its crystal structure and photocatalytic activity, compared to the PhC2Cu nanobelts prepared by thermal-synthesis method. The prepared samples were characterized by X-ray powder diffractometer (XRD), field-emission scanning electron microscopy (FE-SEM), ultraviolet-visible (UV-vis) absorbance spectra and diffuse reflectance spectra (UV-vis Abs and DRS), N2 adsorption-desorption isotherms, FT-IR and Raman spectra. The degradation of MB experiments under visible light irradiation shows that the photocatalytic activity of PhC2Cu prepared by photo-synthesis method is much higher than that by traditional thermal-synthesis method. Moreover, the photocatalytic mechanism of PhC2Cu nanobelts was further studied by the photocatalytic generation of O2 • and •OH.