Both endurance- and resistance-type exercise prevents neurodegeneration and cognitive decline in mice with impaired glucose tolerance

Jinhee,Woo,Ki-Ok,Shin,Chan-Ho,Park,Byung-Kon,Yoon,Do-Yeon,Kim,Ju-Yong,Bae,Yul-Hyo,Lee,Kangeun,Ko,Hee-Tae,Roh 한국응용과학기술학회 (구.한국유화학회) 2019 한국응용과학기술학회지 Vol.36 No.3

The purpose of this study was to investigate the effects of different types of exercise training on neurodegeneration and cognitive function in mice with impaired glucose tolerance (IGT). Thirty-six male C57BL/6 mice were randomly assigned to the control (CO, n = 9) and impaired glucose tolerance (IGT, n = 27) groups. The IGT group consumed 45% high fat diet for 4 weeks and received 40 mg/kg of streptozotocin twice in the lower abdomen to induce IGT. After the IGT induction period, the IGT group was subdivided into IGT + sedentary (IGT, n = 9), IGT + endurance exercise (IGTE, n = 9), and IGT + resistance exercise (IGTR, n = 9). The IGTE and IGTR groups performed treadmill and ladder climbing exercises 5 times per week for 8 weeks, respectively. Fasting glucose and glycated hemoglobin (HbA1c) levels were significantly higher in IGT group than in CO, IGTE, and IGTR groups ( p < 0.05). HOMA-IR was significantly higher in IGT group than CO group ( p < 0.05). Hippocampal catalase (CAT) was significantly lower in IGT group than in CO group ( p < 0.05), while beta-amyloid (Aβ) was significantly higher in IGT group than in CO group ( p < 0.05). Hippocampal tau was significantly higher in IGT group than in CO, IGTE, and IGTR groups ( p < 0.05). The Y-maze test performance for cognitive function was significantly lower in IGT group than in CO, IGTE, and IGTR groups ( p <0.05). These results suggest that IGT induces neurodegeneration and negatively affects cognitive function, while regular exercise may be effective in alleviating neurodegeneration and cognitive decline regardless of exercise type.

Effect of resistance training at different intensities on hippocampal neurotrophic factors and peripheral CCL11 levels in obese mice

Jinhee,Woo,Hee-Tae,Roh,Chan-Ho,Park,Byung-Kon,Yoon,Do-Yeon,Kim,Ki-Ok,Shin 한국응용과학기술학회 (구.한국유화학회) 2019 한국응용과학기술학회지 Vol.36 No.3

We investigated the effect of moderate- and high-intensity resistance training on hippocampal neurotrophic factors and peripheral CCL11 levels in high-fat diet (HFD)-induced obese mice. C57/black male mice received a 4 weeks diet of normal (control, CON; n = 9) or a high-fat diet (HF; n = 27) to induce obesity. Thereafter, the HF group was subdivided equally into the HF, HF + moderate-intensity exercise (HFME), and HF + high-intensity exercise (HFHE) groups ( n = 9, respectively), and mice were subjected to ladder-climbing exercise for 8 weeks. The hippocampal brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) levels were significantly lower in the HF group than in the CON group ( p < 0.05). In addition, in the HFME and HFHE groups were significantly higher than in the HF group ( p < 0.05). The peripheral CCL11 levels were significantly higher in the HF group than in the CON group ( p < 0.05). In addition, in the HFME and HFHE groups were significantly lower than in the HF group ( p < 0.05). However, there was no significant difference according to the exercise intensity among the groups. Collectively, these results suggest that obesity can induce down-regulation of neurotrophic factors and inhibition of neurogenesis. In contrast, regardless of exercise intensity, resistance training may have a positive effect on improving brain function by inducing increased expression of neurotrophic factors.

ANALYSIS OF BODY MEASUREMENT ERROR ABOUT 3D SCAN DATA FOR ELDERLY

Jinhee Park,Juwon Chung,Yu Hwa Hong,Yun Ja Nam 글로벌지식마케팅경영학회 2015 Global Fashion Management Conference Vol.2015 No.06

Measuring body size with a 3D scanner can reduce inter-measurer variability and provide better accuracy compared to using a traditional methods of measurement (Park, Nam, & Park, 2009). Many size measurement projects (or studies) that measure body size established a size measurement method prior to the development of a 3D scanner and automatic size measurement programs that produce 3D virtual body size measurements (Park, &Nam, 2012). Size data measured through an automatic size measurement program are more accurate and have a lower variability that is more appropriate for body measurements (Han, & Nam, 2004; Nam, Choi, Jung, & Yun, 2004). However, this method is limited to healthy subjects who can maintain a correct posture in a 3D scanner. It is difficult for the elderly to maintain the correct posture for body measurements in ‘Basic Human Body Measurements for Technological Design’ of ISO 7250(1997). Body measurement definitions are based on vertical and horizontal directions consequently, it is hard to measure those with a bent body type even if they stand in a correct posture. Most body measurement items are automatically measured in vertical and horizontal directions because current automatic size measurement programs utilize algorithms based on typical body measurement definitions. The size measurement method based on a vertical and horizontal directions tends to have a problem for elderly individuals with a bent body type who have difficulty maintaining a correct posture for 3D scanning as defined in ISO 7250(1997)(Ashdown, & Na, 2008).This study analyzes the problem of present auto-measurement programs that use elderly’s 3D body scan data. We conducted a comparative analysis of elderly’s body sizes using an auto-measurement program from virtual 3D body scan data and direct measurement with traditional measurement methods. We establish 34 typical body size measurements for the use of data from 464 males and 472 females (total 936) between the ages of 70 to 85. For error analysis, data separated to normal values and outliers compared with ISO 20655(2003). ISO 20685 defines the accuracy of extracted measurements by classification and measurement type (segment lengths, body height/breaths/depth, large/small circumferences, and head/hand/foot dimensions). The majority of outliers for the male and female body height type was “height”. Total number of persons with outliers for Height’s data was 603; consequently, 64.4% of subjects (elderly group of 70-85 yrs.) could not maintain a correct posture when scanning. Other data also had many errors from inaccurate measurement postures. A total of 72.3% of males and 70% of females have incorrect values in small circumferences. The segment lengths’ error data was 76.5% of males and 75% of females; in addition, the head dimension’ outliers were 87% for both male and female subjects. Especially 57.46% of males had incorrect data, while 74.67% of females had a type of large circumference. Female chest circumference had significant errors due to sagging breasts. The differences identify with a correlation between type of large circumference (chest, hip, under bust, waist, waist of omphalion) and gender. There were several correlations between the many measurement errors because values over 70% of data have outliers; however, each measurement type has properties in regards to correlation. A substantial positive correlation was found between all measurements (except hip circumference) in the type of large circumference; in addition, one-way ANOVA indicated that the measurements influenced height and were statistically significant. Outliers found in height data for the elderly’s were more likely to have errors in the type of large circumference. The type of body height indicated a strong correlation and statistical significance between the axilla height and other measurements (height, waist, crotch, lateral malleolus). Axilla height with more outliers indicated that other type of body height measurements had a higher potential for errors. The posture for body measurement was standardized as standing erect; however, this study indicated that many measurement errors were possible between using an auto-measurement program and direct measurement. The value of outlier about a particular measurement item can expect increased errors about any group (height: large circumference group/ axilla height: body height group). We have to study the relation in measurements in these types ‘large circumference’ because ‘head dimensions’ types correlate between measurements in each group. We need a more detailed analysis about outliers to find the major factors for measurement errors in regards to the elderly as well as discuss the possibility of ISO measurement-standard’s application for the elderly.

Derivation of the Water Quality Criteria for Cadmium and Lead by Using the Statistical Technique

Jinhee Park(박진희),Woo-Jung Kim(김우중),Jaehoon Yeom(염재훈),Sang Don Kim(김상돈) 환경독성보건학회 2016 한국독성학회 심포지움 및 학술발표회 Vol.2016 No.10

A Study on Emotional Classification Algorithm using Vibraimage Technology

Jinhee Park,Kwan Choi,Sungteak Hwang 대한인간공학회 2014 대한인간공학회 학술대회논문집 Vol.2014 No.5

According to the growth of mechanical and technical development of IT technology, development of new technologies has been attempted by combining the human sensitivity into the existing technology. Particularly, studies to predict recognition based on the physiological signal sensitivity are performed actively. Signal quality of the direct contact sensor is accurate but it is inefficient to use, and the sensitivity measurement of physiological responses of human beings through contact sensing has environmental limitations such as the existing burden and uncomfortable feeling of wearing. Thus, techniques that can be detected by recognizing sensitivity in a free range are required to overcome these problems. In this study, the Vibraimage(vibration imaging) technology based on vestibulo-emotional reflex (VER) is trying to classify on the basis of the sensitivity of two-dimensional emotion model as the non-contact sensing technology. Russell"s emotional state model based on the pleasure, displeasure, arousal, relaxation was given as the emotional stimuli. In accordance with confirming the pattern of emotional changes through parameters acquired from the vibration imaging techniques, as a non-contact sensing technology, the Vibraimage technology contributes to the study of sensitive classification.

Comparison of Measurement Error from Anthropometric measurement due to Age Group Difference

Jinhee Park,Sung Hee Ahn,Yun-Ja Nam,Myung Hwan Yun 대한인간공학회 2014 대한인간공학회 학술대회논문집 Vol.2014 No.11

Objective: The purpose of this study is to find body dimensions where measurement errors occur in recording anthropometric data from the elderly over seventy and to compare the results to the participants in their forties. This is required to find the reason why the errors are induced and to minimize them. Background: Anthropometric data from elderly population is demanded by many industries in an aging society. The sixth Size Korea survey has been being undertaken to measure the particular population aged from 70 to 85. However, the way to improve the accuracy of the measurement has not been studied enough when the target population is limited. Method: the experiment was conducted on the participants in their forties and seventies to measure the particular body dimensions and repeated five times in total. From the repeatedly measured data, values of technical error of measurement (TEM) were acquired and statistically compared by age, sex and dimension as well as trial. Results: By comparing TEMs from forties, which were repeatedly measured, it was found that the error of a certain circumstance could be reduced by training the measurer. Moreover, the result which compared the forties and seventies showed that there was no significant difference either in age or in sex. On the other hand, a particular dimension was significantly different from others. Conclusion: According to this study, TEM did not vary due to changes in body shape as people age, and this means that the accuracy or level of expertise is more important in measuring the elderly. Application: It is needed to be discussed whether the existing method to categorize dimensions in selecting value of TEMis better than others.

Pt Nanoparticle-Reduced Graphene Oxide Nanohybrid for Proton Exchange Membrane Fuel Cells

Park, Dae-Hwan,Jeon, Yukwon,Ok, Jinhee,Park, Jooil,Yoon, Seong-Ho,Choy, Jin-Ho,Shul, Yong-Gun American Scientific Publishers 2012 Journal of Nanoscience and Nanotechnology Vol.12 No.7

<P>A platinum nanoparticle-reduced graphene oxide (Pt-RGO) nanohybrid for proton exchange membrane fuel cell (PEMFC) application was successfully prepared. The Pt nanoparticles (Pt NPs) were deposited onto chemically converted graphene nanosheets via ethylene glycol (EG) reduction. According to the powder X-ray diffraction (XRD) pattern and transmission electron microscopy (TEM) analysis, the face-centered cubic Pt NPs (3-5 nm in diameter) were homogeneously dispersed on the RGO nanosheets. The electrochemically active surface area and PEMFC power density of the Pt-RGO nanohybrid were determined to be 33.26 m2/g and 480 mW/cm2 (maximum values), respectively, at 75 degrees C and at a relative humidity (RH) of 100% in a single-cell test experiment.</P>

Financial S tress in t he A sian C hristian Immigrant Community During COVID-19

Jinhee Park,Roy K. Chen,Chu-Ling Lo,Heekyung Lee 한국상담학회 2023 Journal of Asia Pacific counseling Vol.13 No.2

The purpose of the current study was to examine how individual, economic, and psychological factors contributed to the financial concerns of Asian Christian immigrants in the U.S. during the COVID-19 pandemic (i.e., the impact of COVID-19 on employment status and income change, intolerance of uncertainty, hope, and personal meaning in life). The sample consisted of 103 immigrants from three East Asian countries affiliated with Christian churches. A hierarchical regression analysis was conducted to observe how the aforementioned variables predicted the participants’ financial worries. The results showed that intolerance of uncertainty accounted for a significant amount of variance in financial worries among the participants, but the impact of COVID-19, hope, and meaning in life did not predict significant variance. Implications for practice and future research were discussed.

Analysis of Promoter Elements for Transcriptional Expression of Rat p53 Gene in Regenerating Liver

Park, Jong-sang,Choi, Jinhee,Lee, minhyung,Park, Sunhee,Song, Haisun,Yu, Sunhee The Korea Science and Technology Center 1999 BMB Reports Vol.32 No.1

We previously found three transcription factor-binding motifs in the rat p53 promoter. They are two recognition motifs of NF1-like protein (NF1-like element 1 : -296~-312, NF1-like element 2:-195~-219) and a bHLH protein binding element (-142~-146). In this study, we investigated the DNA-protein complex formation of the three elements with nuclear extracts from both normal and regenerating liver to find the element involved in the induced transcription of p53. The level of each DNA-protein complex on NF1-like and bHLH motifs was not changed. Instead, a new element located at-264~-284 was detected in the DNase I footprinting assay with regenerating nuclear extract. This element has partial homology to the AP1 consensus motif. However, the competition studies with diverse oligonucleotides suggest that the binding protein is not AP1. An in vitro transcription assay shows that this element is important for the transcriptional activation of the rat p53 promoter. Therefore, for the induced transcription of the rat p53 promoter, the-264~-284 region is required in addition to two NF1-like and one bHLH motif.

Orchard Variation Differentially Induced the Incidence of Lenticel Blotch by Mediating Major Metabolites and Mineral Nutrients in Peel Tissues of Cold-Stored Apples

Jinhee Lee,Hyowon Park,Si-Eun Byeon,Theint Thandar Latt,Sangyo Jeong,Jiwon Park,Hnin Phyu Lwin,Jong Taek Park,Young Soon Kwon,Jung Hee Kim,Soon-il Kwon,Ha-il Jung,Hee-Seung Park,Jinwook Lee 한국원예학회 2024 한국원예학회 학술발표요지 Vol.2024 No.5