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        Ultramini nephrostomy tract combined with flexible ureterorenoscopy for the treatment of multiple renal calculi in paediatric patients

        Jingyang Guo,Wen Zeng Yang,Yanqiao Zhang,Feng An,Ruojing Wei,Yu Li,Haisong Zhang 대한비뇨의학회 2015 Investigative and Clinical Urology Vol.56 No.7

        Purpose: To assess the safety and efficacy of an ultramini nephrostomy tract, which we were using for the first time, combinedwith flexible ureterorenoscopy (URS) in the treatment of pediatric patients with multiple renal calculi. Materials and Methods: Twenty pediatric patients (age, ≤6 years) underwent ultramini percutaneous nephrolithotomy (PCNL)combined with flexible URS. The group had multiple renal calculi, which were bilateral in 3 cases and were located in a total of 23sites. The calculi were located in 2 calyces in 10 cases, scattered in more than 2 calyces in 7 cases, and limited to 1 calyx in 3 cases. The average patient age was 37.35 months (range, 14–68 months). The average stone diameter was 2.0 cm (range, 1–3.0 cm). Inall patients, an ultramini nephrostomy tract was established under ultrasound guidance (dilated to F10) with simultaneous sheathplacement. The flexible URS was placed into the collecting system during holmium laser lithotripsy. Results: When ultramini PCNL was combined with flexible ureterorenoscopic holmium laser lithotripsy, the complete stone-freerate was 87% (20/23). The average level of hemoglobin decreased to 1.0 g/dL after the operation. No blood transfusions wereneeded. Levels of blood urea nitrogen, creatinine, and C-reactive protein were not significantly different before and after the operation. The average duration of hospitalization was approximately 4.85 days, and all cases were followed up for 6 to 12 months. No complications were found. Conclusions: Ultramini PCNL combined with flexible ureterorenoscopic holmium laser lithotripsy is a safe and effective treatmentfor children with multiple renal calculi.

      • A Novel Algorithm for Aggregating the Topological Nodes in Web GIS Network Management

        Min Huang,Likun Zhu,Pengfei Liu,Jingyang Wang,Liwei Guo 보안공학연구지원센터 2015 International Journal of Database Theory and Appli Vol.8 No.1

        The problems of the icons covering each other and slow data loading are very challenging when the GIS technology is applied to load a large number of topological nodes. A novel algorithm for aggregating the topological nodes in GIS based on the hierarchical clustering algorithm is presented in this paper. Comparison with the hierarchical clustering algorithm and partitioning algorithm is explored. In addition, the implementation of the algorithm is derived. The experiment demonstrates that the algorithm solved the problems of the icons covering each other and slow data loading effectively, realized the aggregation of the topological nodes preferably, and presented the distributed trend of the topological nodes and the topology relation between each other in the topology. The experimental results verify the effectiveness of the method.

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        Construction of graphene/AuNPs based amperometric immunosensor for detecting bladder cancer biomarker apolipoprotein A1

        Jing Yang,Wang Xingyuan,Zhou Tingting,Wei Liangjun,Guo Meiling,Liu Yanan,Sun Xiaoqi,Wang Yanjie 한국탄소학회 2024 Carbon Letters Vol.34 No.3

        This paper presents the construction and characterization of an amperometric immunosensor based on the graphene/gold nanoparticles (AuNPs/GO) nanocomposite for the detection of the bladder cancer biomarker, apolipoprotein A1 (Apo-A1). The morphological analysis of the AuNPs/GO nanocomposite demonstrated an almost spherical shape of AuNPs and the successful coverage of their surface by graphene oxide. An increased G peak and decreased D peak after the association of AuNPs with GO, implied a reduction in graphene defects. The X-ray photoelectron spectroscopy (XPS) indicated a significant decrease in the quantity of oxygen-containing functional groups in the AuNPs/GO nanocomposite, as compared to the original GO. Furthermore, the developed sensor demonstrated commendable sensitivity and selectivity, with a wide linear range for Apo-A1 detection. Importantly, the immunosensor exhibited remarkable stability over a period of 14 days, signifying its potential for practical applications.

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