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      • 생체분해성 고분자의 특성 및 의학적 응용

        이진호,최선웅,강길선,노승무,민병무,김용백,김학용 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

        "Biomaterials" are nonviable materials used in medical devices, intended to interact with biological systems. They should have "biocompativility", which is defined as the ability of materials to perform with an appropriate host response in a specific application. It includes many materials that are often classified as biomaterials. Metals, ceramics, polymers, glasses, carbons, and composite materials are some examples. Among them, biodegradable polymers are discussed in this revies article. Since a biodegradable polymeric implant does not have to be removed surgically once it is no longer needed, biodegradable polymers are of value in short-term applications that require only the temporary presence of a polymeric implant. Main short-term medical applications of biodegradable polymers include the temporary tissue scaffold, the temporary adhesion barrier, the drug delivery device, and the multifunctional implant. In this article, the properties, processing methods, and medical applications of the biodegradable polymers are reviewed.

      • 小員環 化合物에 關한 硏究 : Li-Bistosylhydrazone의 熱分解 生成物에 關하여 Products of the Lithium Fumaraldehyde Bistosylhydrazone Pyrolysis

        李學沂,林龍進,沈相喆 경북대학교 공과대학 1971 工大硏究誌 Vol.1 No.-

        The pyrolysis of dry lithiun salt of fumaraldehyde tosylhydrazone which was prepared by reacting fumaraldehyde and tosylhydrazine was studied. The products of therm a decomposition, acetylene, ethytlene and unidentified gaseous substances, were separated by GC to learn the ratio of the products which was variable according to the reaction conditions. The investigaton of the path route to form acetylene, ethylene and unidentified compounds remains for further work to learn the mechanism of tetrahedrane formation.

      • 위암 환자의 복강내 투여를 위한 Activated Charcoal-Alginate Bead 제형으로부터 Mitomycin C의 용출 거동

        이진호,최선웅,서중기,김동민,정경수,오정연,김진향,노승무,민병무,김용백,김창식,박근성,강대영,송규상,양준묵,조준식,정현용,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

        Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherapy seems a logical choice for cancer chemotherapy. In this study, Mitomycin C (MMC)-activated charcoal (CH)-alginate (ALG) beads were prepared by the mixtures of CH particles adsorbed with MMC as an anti-cancer drug and aqueous alginate solution. The alginate is recognized as biodegradable, nontoxic, and biocompatible. The release of MMC from the beads in 0.1 M Tris buffer was stable and continuous until about 1 week. The MMC-CH-ALG beads can be applied in the peritoneal cavity for intraperitoneal chemotherapy since they provide a good adhesiveness on the tissue and controlled release pattern of the drugs.

      • 韓國 알미늄 箔産業의 마케팅 戰略

        李容鶴,文學鎭 수원대학교 기업경영연구소 1992 企業經營硏究 Vol.1 No.-

        Korean Aluminium Foil Industry has grown, during the last five years, as the average annul growth rate was 19.1%, But in the late 80's, with the new foil manufacturers participation, the already established manufacturers have worried over the increased production capacity. The industry is in a transitional stage changing from excess demand to excess supply. The study suggests the marketing strategy for the Korean Aluminium Foil industry as follows. First, the industry needs to reform its management from the reproduction emphasis to marketing emphasis. With the product surplus, the manufacturers have to sell to survive by the circulation of production -sales-reproduction. Second, through a marketing mix, the industry has to promote a new demand and enhance the marketability without pricing competitiveness. There has to be an effort to develop a new product, as well as enhancing the product quality. Third, aggressive export strategy has to be developed. And lastly, Green Marketing should be introduced into the Aluminium Foil industry.

      • 난소절제후 Estrogen을 투여한 흰쥐 대동맥에서 Protein Kinase C-α와 Fas 발현의 변화

        이왕수,이상엽,안지현,송영빈,김학진,이광재,유재격,김상욱,김태호,김치정,류왕성 중앙대학교 의과대학 의과학연구소 2001 中央醫大誌 Vol.26 No.3

        Estrogen is believed to decrease coronary artery disease. Protein kinase C-α(PKCα)appear to be important in signal conduction pathways. Estrogen treatment increases catalytic activity of PKCα,and activation of PKCαcan modulate estrogen receptor levels and responsiveness. And it was reported that activation of PKC can protect cells from apoptosis induced by Fas ligation. But the beneficial effect of estrogen on PKCαwas not clearly demonstrated. The objective of this study was to evaluate the role of PKCαafter ovariectomy and estrogen therapy in rat aorta. The results were summarized as below: 1. The significant pathological changes were not observed in the rat aorta irrelevant to ovariectomy and estrogen therapy. 2. The expression of Fas was decreased in the aorta of estrogen-treated rats than that of ovariectomized rats without estrogen therapy. 3. Increased expression of PKCαwas more marked in the aprta of estrogen-treated rats than that of ovariectomized rat without estrogen therapy. In conclusion,PKCαmay be important in signal conduation pathway on the effect of estrogen. Activation of PKCαby estrogen reduced Fas expression, suggesting that PKCαactivation may play a role in protection against atherasclerosis. Further studies are needed to elucidate the role of PKCαafter estrogen therapy.

      • 뭉툭맵시벌아과(벌목:맵시벌과)의 분류와 계통 : Ⅰ. 현상학적 분석 Ⅰ. Phenetic analysis

        이종욱,차진열,박원학 嶺南大學校 基礎科學硏究所 1995 基礎科學硏究 Vol.15 No.-

        For the phenetic analysis of the subfamily Tryphoninae(Hymenoptera:Ichneumonidae), specimens were collected from March of 1988 to September of 1995 in the southem part of Korean peninsula. Specimens were also obtained from various museums and laboratories both in Korea and other counteries. This research utilized about 1000 domestic specimens and 3010 foregin specimens including 10 specimens from North Korea. Phenetic analysis was performed using these specimens (39 genera 39 species)and the following results were obtained. In the cluster analysis, the ward method is more effective than the average linkage method (within group and between group), while the use of total characteristics was resulted in more stable grouping than only quantitative or qualitative characteristics. The cluster and discriminant analyses suggested that the Townes(1969) and Townes et al.(1992)'s system is well fit for the classification of Tryphoninae. For the subfamiliar classification, the analyses of total characteristics by ward method resulted in the most accetable grouping.

      • 영어의 전치사와 한국어의 후치사와의 대조연구

        이영헌,장태진,최용재,조학행 朝鮮大學校 師範大學 1976 師大論文集 Vol.7 No.-

        두 언어 사이의 대조연구는 그 방법론에서 우선 "주어진 두 언어를 각각 따로 기술하고 그 결과를 대조하여 다른 점을 발견해 내는 것"으로 되어 있다. 이 정의를 이 연구에 적용한다면 영어의 전치사에 대한 모든 기술을 해 놓고 그것과 상관되는 한국어의 어떤 형태를 또한 독자적으로 기술 해 놓은 다음에 이 두가지 서술들을 서로 대조해 보아야 한다. 그러나 이 연구에서는 오히려 그 과정을 반대로 하여 서로 대응되는 것들을 찾아 내고 그것들의 어떤 공통된 유형을 모색해 보려고 한다. 그 이유로서는 본 연구가 문법체계 전반에 걸친 대조가 아니고 극히 특정적인 일부분에 국한 된 것이며 대조의 대상들도 서로 선명히 대응되는 것들이 아니기 때문이다. 더구나 이 연구가 추구하는 부분에서는 한국어와 영어 사이에 아무런 유사성도 발견되지 아니 한 것 같고 오히려 상이점만이 두드러지게 나타나고 있기 때문이다. 그러므로 본 연구의 결과가 상이점의 나열에 그칠 수도 있으며 발견된 대응점의 기계적 서술에 그칠 수도 있다. 그러나 워낙 이 연구의 목적이 거기에 있는 이상 방법론의 새로운 적용은 여기에서만은 타당하다고 볼 수 있다. 물론 이 연구의 효용에 대하여서는 대조분석의 효용이라는 원칙적 문제에까지 소급하여 생각하지 아니 할 수 없으나. 대조분석이 갖는 많은 문제점에도 불구하고 상당히 희망적이다. 대조분석이 노리는 점은 항상 차이점 또는 상이점의 발견이지만, 이 연구는 어떤 기계적 대응관계를 찾으려는 것이기 때문에 그것이 직접 학습과 번역에 도움이 될 것이란 기대가 결코 지나치다고는 할 수 없을 것이다. 이 연구의 결과는 이미 약간 언급한 바와 같이 교제의 편찬을 위한 것이 아니고 단순히 영어학습자에게 전치사를 지도하는 데 있어서 우리말과 대응되는 점을 일깨워 줌으로서 영문국역에 어떤 기계적 대조에 가까운 색인을 주려는 것이다. 여기서 기계적이라고 함은 번역에 있어서 어느 정도의 정확성을 주려고 하는 의도를 나타낸 것이다. 다시 말하면 컴퓨터에 넣을 수 있을 정도로 일대일로 대응되는 색인은 기대할 수 까지는 없다는 것이다.

      • 고성토의 암성토에 대한 흙의 함유율이 다짐에 미치는 효과에 관한 실험적 연구

        이종출,이영대,정진호,류재학,정두회 釜慶大學校 1999 釜慶大學校 論文集 Vol.4 No.1

        We have carried out the field compaction tests in the site in which the high rock fill embankments are going to be constructed about 25m in height, to examine the effect of the soil fraction to the total embankment materials which are the mixture of rock fills and soils on the degree of field compaction. We have made four sets of in-situ concrete boxes of the size of 1.5m×1.5m×0.6m to obtain the maximum dry density of total embankment materials after compacting by using a 10-ton vibrating tamping roller. We have found, as a result, that the optimum passing number of the roller to yield the 90% of relative compaction economically attainable has appeared to be 8 passes, and that the percent of the soil fraction to the total embankment materials to yield the 90% of relative compation in the field has appeared to be 41.78% by weight.

      • 토착형 말라리아 (Plasmodium vivax) 2례

        이영진,박도심,정병학 圓光大學校 醫科學硏究所 1997 圓光醫科學 Vol.13 No.1-2

        In korea indigenous malaria was known as "Hak-chil" in many centuries and they were disappeared from 1984 to 1992. But indegenous malaria (Plasmodium vivax) was detected in 1993 among soldiers and residents in western parts of the demilitarized zone (DMZ). Nowadays infected cases of indeginous malaria are progressively increased and social problem because infected mosquitos and bloods can transmit to other people. We detected 2 cases of indigenous malaria (P.vivax) that they were worked in western parts of the demilitarized zone (DMZ) during army period few months ago but never went out of korea, received blood products and intravenous drugs. We considered that they were were infected malaria at DMZ.

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