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- 저자 : Jieg, Jiu (검색결과 2 건)
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양승의,유걸,정회경,Yang, Seung-Eui,Jieg, Jiu,Jung, Hoe-Kyung 한국정보통신학회 2013 한국정보통신학회논문지 Vol.17 No.3
최근 증강현실(Augmented Reality, AR)에 대한 연구가 활발히 진행 중이고, 소셜 네트워크 시스템(Social Network System)에 증강현실 기능의 추가 필요성이 부각되고 있다. 본 논문에서는 소셜 네트워크를 위한 GPS기반 증강현실 시스템을 제안한다. 제안한 시스템은 페이스북(facebook)에서 친구 목록을 자동으로 동기화하여 최근 체크인 좌표를 추가하고, AR을 이용하여 추가된 위치 좌표를 실제 환경에서 표현하는 시스템이다. 기존 이용자들이 사용했던 마커기반 AR 시스템은 핸드 장치 구동에 필요한 프로세싱 빈도와 저장 공간의 소모가 많다. 그러나, 위치기반 AR어플리케이션은 기존 마커기반 AR 시스템의 단점을 해결 할 수 있다. 따라서, 본 논문의 시스템은 향후 iOS 핸드 장치를 가지고 있는 사용자가 GPS기반 AR 시스템을 Wifi와 4G 네트워크에 대해 최적의 속도를 자동으로 검색하여 소셜 네트워크 서비스의 제공이 가능하다. Recently, researches on augmented reality(AR) are actively being conducted, and on addition of AR in social network system has become a necessity. In this paper, we propose GPS-based AR system for social network. This proposed system adds the recent check-in coordinates by automatically synchronizing a friend list in facebook and represents those added location coordinates in a real-world environment by using AR. Marker-based AR system that was commonly used by existing users consumes too much storage space and processing frequency for driving handle devices. But, location-based AR application can solves the disvantages of the standard marker=based AR system. Therefore, this proposed system allows an user with iOS hand devices to use GPS-based AR system by automatically searching the optimal speed for wifi and 4G. This will improve social network service.
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Wu Hao,Wei Guoli,Luo Lixia,Li Lingchang,Gao Yibo,Tan Xiaobin,Wang Sen,Chang Haoxiao,Liu Yuxi,Wei Yingjie,Song Jie,Zhang Zhenhai,Huo Jiege 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00
Combination of chemotherapy and immune checkpoint inhibitor therapy has greatly improved the anticancer effect on multiple malignancies. However, the efficiency on triple-negative breast cancer (TNBC) is limited, since most patients bear “cold” tumors with low tumor immunogenicity. Doxorubicin (DOX), one of the most effective chemotherapy agents, can induce immunogenic cell death (ICD) and thus initiating immune response.In this study, to maximize the ICD effect induced by DOX, chitosan and cell-penetrating peptide (R6F3)-modified nanoparticles (PNPs) loaded with ginsenoside Rg3 (Rg3) were fabricated using the self-assembly technique, followed by co-encapsulation with DOX based on thermo-sensitive hydrogel. Orthotopic tumor model and contralateral tumor model were established to observe the antitumor efficacy of the thermo-sensitive hydrogel combined with anti-PD-L1 immunotherapy, besides, the biocompatibility was also evaluated by histopathological.Rg3-PNPs strengthened the immunogenic cell death (ICD) effect induced by DOX. Moreover, the hydrogel co-loading Rg3-PNPs and DOX provoked stronger immune response in originally nonimmunogenic 4T1 tumors than DOX monotherapy. Following combination with PD-L1 blocking, substantial antitumor effect was achieved due to the recruitment of memory T cells and the decline of adaptive PD-L1 enrichment.The hydrogel encapsulating DOX and highly permeable Rg3-PNPs provided an efficient strategy for remodeling immunosuppressive tumor microenvironment and converting immune “cold” 4T1 into “hot” tumors.
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