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        Longitudinal Assessment of Intravoxel Incoherent Motion Diffusion Weighted Imaging in Evaluating the Radio-sensitivity of Nasopharyngeal Carcinoma Treated with Intensity-Modulated Radiation Therapy

        Youping Xiao,Ying Chen,Yunbin Chen,Zhuangzhen He,Yiqi Yao,Jianji Pan 대한암학회 2019 Cancer Research and Treatment Vol.51 No.1

        Purpose Intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) was evaluated regarding its ability to preliminarily predict the short-term treatment response of nasopharyngeal carcinoma (NPC) following intensity-modulated radiation therapy. Materials and Methods IVIM-DWI with 14 b-factors (0-1,000 sec/mm2) was performed with a 3T MR system on 47 consecutive NPCs before, during (end of the 5th, 10th, 15th, 20th, and 25th fractions), and after fractional radiotherapy. IVIM parametrics (D, f, and D*) were calculated and compared to the baseline and xth fraction. Patients were categorized into responders and non-responders after radiotherapy. IVIM parametrics were also compared between subgroups. Results After fractional radiations, the D (except D5 and D at the end of the 5th fraction) after radiations were larger than the baseline D0 (p < 0.05), and the post-radiation D* (except D*5 and D*10) were smaller than D*0 (p < 0.05). f0 was smaller than f5 and f10 (p < 0.001) but larger than fend (p < 0.05). Furthermore, greater D5, D10, D15, and f10 coupled with smaller f0, D*20, and D*25were observed in responders than non-responders (all p < 0.01). Responders also presented larger D10, f10, D*20, and D*20 than non-responders (p < 0.05). Receiver operating characteristic curve analysis indicated that the D5, D*20, and f10 could better differentiate responders from non-responders. Conclusion IVIM-DWI could efficiently assess tumor treatment response to fractional radiotherapy and predict the radio-sensitivity for NPCs.

      • Improved Feedforward to Enhance Harmonic Suppression for Grid-Connected Inverter

        Boyang Liu,Hua Lin,Jianjie Xiao 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5

        In most cases, for grid-connected inverters, the grid is not ideal at the point of common coupling. When proportional feedforward is used to suppress grid voltage harmonics, the existence of grid impedance will deteriorate the stability of grid-connected LCL-filtered inverter. To enhance stability, the multi-resonant feed-forward strategy was proposed in some papers. However, because of the phase lag caused by digital delay, the suppression ability of this method to grid harmonics is not good enough. Therefore, this paper proposes a compensation strategy for phase lag of feedforward channel at resonant frequencies, which makes different resonant frequencies correspond to different dq rotation coordinates, and respectively changes initial phase of every dq rotation coordinate properly to compensate phase lag. Then the ability to suppress grid harmonics is obviously enhanced. Finally, experimental results verify the effectiveness of proposed control strategy.

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