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      • KCI등재

        PH 4.3에서 재광화 용액의 포화도에 따른 인공 탈회된 법랑질의 동력학적 변화

        이지숙,노병덕,신수정,이윤,공형규,이찬영 대한치과보존학회 2009 Restorative Dentistry & Endodontics Vol.34 No.1

        법랑질의 재광화에 영향을 주는 요인으로는 PH, 불소 농도, 포화도 등이 있다. 본 연구에서는 유산 완충 탈회용액을 이용하여 법랑질 시편을 인공 탈회시킨 후, pH 4.3에서 포화도를 0.22, 0.30, 0.35로 달리한 세가지 재광화 용액에 10일간 처리하여 나타나는 변화를 편광현미경으로 관찰하여 전체 탈회 깊이와 건전 표층 폭의 변화를 조사하였다. 또한 Image program (Scion Image analyzer)을 이용하여 병소 부위의 평균 mineral density를 측정하여 탈회와 재광화 후 무기질 변화량을 통해 인공 탈회된 법랑질의 동력학적 변화를 관찰하였다. 1 재광화 후 모든 군에서 건선 표층의 폭이 증가하였는데, 포화도가 증가할수록 건전 표층 폭이 증가하였다 (P< .05) 2 재광화 후 mineral density 변화를 관찰한 결과 포화도가 낮은 군에서는 이온의 침착이 병소 전반적으로 일어났으나, 포화도가 높은 군에서는 건전 표층 부위와 표층하 병소의 하층부에서 이온의 침착으로 mineral density 가 증가하였고 표층하 병소의 상층부에서는 탈회가 진행되어 mineral density가 감소하였다. 3 재광화 후 모든 군에서 무기질량이 증가하였고 전체 탈회 깊이도 증가하였으나 각 군간에 통계적 유의차는 없었다. 본 실험에서 인공 탈회된 시편을 pH 4.3인 재광화 용액에 처리시 포화도가 높을수록 건전 표층에서 더 많은 재광화 현상이 일어났고 표층하 병소에서는 재광화 현상이 적게 일어났으며 재광화 후 모든 군에서 전체 탈회 깊이는 증가하였다. The purpose of this study is to observe and compare the dynamic change of artificially demineralized enamel by remineralization solutions of different degrees of saturation at pH 4.3 In this study, 30 enamel specimens were demineralized artificially by lactic acid buffered solution. Each of 10 specimens was immersed in pH 4.3 remineralization solution of three different degrees of saturation (0.22, 0.30, 0.35) for 10 days. After demineralization and remineralization, images were taken by a polarizing microscope (× 100). The density of lesion were determined from images taken after demineralization and remineralization. During remineralization process, mineral deposition and mineral loss occurred at the same time. After remineralization total mineral amount and width of surfacc lesion increased in all groups. The higher degree of saturation was, the more mineral deposition occurred in surface lesion and the amount of mineral deposition was not much in subsurfacc lesion. Total demineralized depth increased in all groups.

      • KCI등재

        하악골 충격시 안면 두개골의 응력분산양상에 미치는 구강보호장치의 역할에 관한 유한요소법적 연구

        김일한,노관태,노현식,김지연,우이형,Kung-Rock Kwon,최대균 대한치과보철학회 2012 대한치과보철학회지 Vol.50 No.1

        연구 목적: 이 연구의 목적은 하악골 충격 시 안면 두개골의 응력 분산양상에 미치는 구강보호장치의 효과에 대해 조사하는 것이다. 연구 재료 및 방법:: 구강보호장치를 제작하고 사람의 머리부위와 치열의 3차원적 유한요소 모델을 컴퓨터 토모그래피를 사용하여 제작하였다. 머리부위의 finite element model은 356,092요소와, 87,099절점으로 이루어져 있다. 그리고 skull과 maxillae, mandible, articular disc, teeth, 그리고 구강보호장치로 구성되었다. 경부의 움직임을 묘사하기 위하여 스프링이 사용되었다. 하악골의 충격점은 gnathion, center of inferior border 와 anterior edge of gonial angle이었다. 충격방향은 수직, 경사방향(45 도), 그리고 수평이다. 충격량은 0.1초당 800 N이었다. 결과: 수직충격을 가한 경우에는 구강보호장치의 장착여부와 무관하게 비슷한 응력과 분산양상이 나타났다(P>.05). 경사충격(45 도)을 가한 경우 구강보호장치를 장착한 모델에서는 응력이 치아와 안면골 및 두개골로 넓게 분산되었으나 이에 비하여 장착하지 않은 모델에서는 치아에 응력이 집중되었다(P<.05). 수평충격을 가한 경우 구강보호 장치를 장착한 모델에서는 응력이 치아와 안면골 및 두개골로 넓게 분산되었으나 이에 비하여 장착하지 않은 모델에서는 치아에 응력이 집중되었다(P<.05). 구강보호장치를 장착하지 않은 모델에서는 상악 치아에 응력이 집중되는 반면, 장착한 모델에서는 모든 충격실험에서 계측된 응력이 매우 낮았으며, 전달된 응력이 상악 치아와 안면골 및 두개골로 넓게 분산되었다. 결론: 구강보호장치는 외부충격 시에 하악에 수직으로 가해지는 충격에는 완충효과가 적었고, 45 도 경사 충격과 수평 충격에는 발생하는 응력을 안면골과 두개골의 넓은 범위로 분산시키고 응력을 감소시켜 응력의 완충 효과가 있었다. PURPOSE. The purpose of this study was to investigate the effects of a mouthguard on stress distribution under mandibular impact. MATERIALS AND METHODS. The FEM model of head consisted of skull, maxilla, mandible, articular disc, teeth, and mouthguard. The impact locations on mandible were gnathion, the center of inferior border, and the anterior edge of gonial angle. And the impact directions were vertical, oblique (45 degrees), and horizontal. The impact load was 800 N for 0.1 sec. RESULTS. When vertical impact was applied, the similar stress and the distribution pattern was occurred without the relation of the mouthguard use (P>.05). The model with mouthguard was dispersed the stress to the teeth, the facial bone and the skull when the oblique (45 degrees) impacts were happened. However, the stress was centralized on the teeth in the model without mouthguard (P<.05). The model with mouthguard was dispersed the stress to the teeth, the facial bone and the skull when the horizontal impacts was occurred. However, the stress was centralized on the teeth without mouthguard (P<.05). For all impact loads, stress concentrated on maxillary anterior teeth in model without mouthguard, on the contrary, the stress was low in the model with mouthguard and distributed broadly on maxillary anterior teeth, facial bone, and skull. CONCLUSION. The mouthguard was less effective at shock absorbing when vertical impact was added. However, it was approved that mouthguard absorbed the shock regarded to the oblique (45 degrees) and horizontal impact by dispersing the shock to the broader areas and decreasing the stress.

      • SCIESCOPUSKCI등재

        CASE REPORT : Pigmented Mammary Paget Disease Misdiagnosed as Malignant Melanoma

        ( Ji Hye Lee ),( Tae Hyung Kim ),( Soo Chan Kim ),( You Chan Kim ),( Mi Ryung Roh ) 대한피부과학회 2014 Annals of Dermatology Vol.26 No.6

        Pigmented mammary Paget disease is a very rare clinicopathologic variant of mammary Paget disease. Diagnosis is often difficult because its clinical and histological features are very similar to those of malignant melanoma. Herein, we report a case of pigmented mammary Paget disease misdiagnosed as malignant melanoma. (Ann Dermatol 26(6) 747∼750, 2014)

      • SCIESCOPUSKCI등재

        Isolation of Off-flavors and Odors from Tuna Fish Oil Using Supercritical Carbon Dioxide

        Roh, Hyung-Seob,Park, Ji-Yeon,Park, Sun-Young,Chun, Byung-Soo The Korean Society for Biotechnology and Bioengine 2006 Biotechnology and Bioprocess Engineering Vol.11 No.6

        Off-flavors and unfavorable odors in tuna fish oil were successfully removed and identified using supercritical carbon dioxide extraction, while retaining variable compounds, polyunsaturated fatty acids such as EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid). Samples of oil were extracted in a 100 mL semi-batch stainless steel vessel under conditions which ranged from 8 to 20 MPa and $20\;to\;60^{\circ}C$ with solvent ($CO_{2}$) flows from 10 g/min. GC-MS was used to identify the main volatile components contributing to the off-flavors and odors which included 2-methyl-1-propanol, 2,4-hexadienal, cyclopropane, and octadiene. Analyses of oil extracted at $40^{\circ}C$, 20 MPa showed a 99.8% reduction in dimethyl disulfide. Other significant off-flavors identified were 2-methyl-butene, 3-hydroxy butanal and ethylbenzene.

      • [P040] Rapidly growing nodular fasciitis on the postauricular area

        ( Ji Young Choi ),( Si-hyung Lee ),( Mi Ryung Roh ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

        Nodular fasciitis (NF) a rapid growing, often painful mass in the subcutis, fascia, or muscle demonstrating proliferation of fibroblast. NF can occur at any sites, however, it is relatively rare in the head and neck area in adults. Here, we`d like to present a case of a rapidly growing NF on the ear of a male adult patient. A 40-year old male visited our clinic with a protruding mass on his right postauricular area. The lesion was discovered a month ago and has grown rapidly. A 4mm punch biopsy was performed and histopathology revealed a dense eosinophilic cellular mass in the lower dermis. Spindle cells in a storiform arrangement in “tissue-culture”-like stroma was observed. Immunohistochemical (IHC) staining results were positive for smooth muscle actin, and negative for CD34 and S-100. Head and neck CT scan showed no invasion to neighboring structures. Complete excision was performed and a well-demarcated dermal mass without encapsulation was observed. Recurrence was not observed during our 2 months follow up period. NF on the ear is not common and can show uncommon clinical and histologic feature. Such distinct features might be related with limited redundancy of ear skin. These clinical features may be worrisome for the patient since physicians may explain the possibility of a malignancy. Therefore, knowing these clinical characteristics in addition to the help of IHC stain would be helpful to make an accurate diagnosis of NF.

      • P141 : Combination of surgical subcision and intralesional corticosteroid injection as a cost-effective and minimally invasive treatment for postoperative adhesive thyroidectomy scar

        ( Ji Hye Lee ),( Tae Hyung Kim ),( Yong Sang Lee ),( Hang Seok Chang ),( Cheong Soo Park ),( Mi Ryung Roh ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2

        Background: Postoperative adhesive symptoms are one of the major complications of thyroidectomy. Those symptoms include swallowing difficulty or a pulling sensation during neck extension. Moreover, adhesive scars are often visible and cause cosmetic concerns. Objectives: To evaluate the efficacy and safety of combined treatment of surgical subcision and intralesional coticosteroid injection on postoperative adhesive thyroidectomy scars. Methods: A retrospective analysis of 16 Korean patients with postoperative adhesive thyroidectomy scars who were treated with three sessions of surgical subcision and intralesional corticosteroid injection was performed. Results: The VSS score significantly decreased after treatment (P-value < 0.001). Follow-up results revealed that 6 of the 16 patients (37.5%) demonstrated clinical improvement of 51% to 75%. Six patients (37.5%) had moderate clinical improvement of 26% to 50%, and three (18.8%) showed improvement of 76% to 100%. One patient (6.3%) demonstrated minimal to no improvement. The mean grade of clinical improvement was 2.68. Post-treatment erythema was observed in most of the patients and notable bruising after treatment was observed in five patients and it resolved spontaneously within seven days. Conclusion: We suggest that combined treatment of surgical subcision and intralesional corticosteroid injection is a cost-effective and minimally invasive treatment of treating postoperative adhesive thyroidectomy scar.

      • SCOPUSKCI등재

        Scar Sarcoidosis after Blepharoplasty: A Case Series

        ( Ji Young Choi ),( Ji Hye Lee ),( Tae Hyung Kim ),( Soo-chan Kim ),( Mi Ryung Roh ) 대한피부과학회 2017 대한피부과학회지 Vol.55 No.7

        Scar sarcoidosis is a cutaneous manifestation of sarcoidosis arising on old cutaneous scars. We report four cases of scar sarcoidosis after blepharoplasty. Lesions were seen to manifest as erythematous, firm, and non-tender nodules diffusely palpable along an upper eyelid scar. Histologically, numerous non-caseating granulomas with multinucleated giant cells were seen. No other evidence of systemic sarcoidosis was observed in any patient. Although rare, sarcoidosis may occur in an eyelid scar after a blepharoplasty. Therefore, scar sarcoidosis should be considered in the differential diagnosis in patients presenting with unusual nodules in blepharoplasty scars. (Korean J Dermatol 2017;55(7):460∼464)

      • SCIESCOPUSKCI등재

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