비내시경을 이용한 안와 내벽 골절 정복 2예

김진국,남태욱,임채형,김재영,김정석 건국대학교 의과학연구소 2001 건국의과학학술지 Vol.11 No.-

Traditional surgical approaches to orbital medial wall fractures are either extraocular skin incision or indirect bicoronal flap. However these methods can leave remarkable orbital scar or scalp alopecia with possible complications. Endoscopic intranasal visualization of the medial orbital wall and lamina papyracea is a technique familar to otolaryngologists. This endoscopic view allows confirmation of fracture of medial orbital wall and herniation of orbital contents. Good visualization of the fracture can facilitate the anatomic reduction of orbital contents and the proper placement of orbital implant. Two cases of medial orbital wall fracture repaired by intranasal endoscopy using silastic sheet are reported.

신뢰성에 기초한 PC빔교의 내하력 평가

백용락,정인수,신재철,이상국 忠南大學校 産業技術硏究所 1996 산업기술연구논문집 Vol.11 No.2

In most countries road bridges are subjected to increasingly heavy freight traffic with a number of exceptional truck loads. This has made it necessary to devote particular attention to the evaluation of safety and load-carrying capacity of bridges, which is a vital process in the decision-making for maintenance, repair, strengthening, or even replacement of existing road bridges. However, most countries including Korea do not have a comprehensive rating system or rating code. Furthermore, the current methods of rating of road bridges are dependent on the conventional design concepts and the safety parameters of the current bridge design codes. A practical reliability model for the safety assessment and rating of existing PC beam bridges are developed by explicitly incorporating the degree of deterioration and damages based on available inspection or field test data. AFOSM methods are used for the reliability analysis of the proposed models. The proposed reliability model and methods are applied to the safety assessment of existing PC beam bridges in Korea.

도전재 첨가량에 따른 리튬폴리머 2차 전지 MCMB 부극의 전기적 특성

김상필,정재국,남효덕 嶺南大學校 工業技術硏究所 2002 工業技術硏究所論文集 Vol.30 No.2

Anode characteristics of Lithium Polymer Batteries(LPB) were investigated by adding different contents of conducting agents. Super P Black(SPB), Vapor Carbon Grown Fiber(VGCF) and Kuraha Carbon Fiber(KCF) were used as conducting agents with active material of Mesocarbon Microbeads(MCMB). In consequence, the internal resistance of LPB was decreased by increasing the amounts of conducting agents. AS a result, the conductivity of the battery improved upto 0.27×10 exp (-3)S/㎝, 0.4×10 erxp (-3)-3S/㎝ and 0.36×10 exp (-3)S/㎝ by adding SPB, VGCF and KCF as conducting agents to the anode, compared to that of the anode without conducting agents.

고온에서 회전하는 터빈엔진 디스크의 응력해석

황수철,국정한,조재웅,하영민 한국공작기계학회 1995 한국생산제조학회지 Vol.4 No.4

This study includes thermal plasticity analyses for a turbine rotor with the simple geometry and the boundary conditions. When centrifugal or thermal stress are applied at the high temperarture material of engine blade, stress distributions in material σ_rr, σ_θθ, τ_rθ. Mises stress) are analyzed by computer simulation(ABAQUS) as followings; 1. The maximum stress at the radial direction (σ_rr) is applied at the upper middle part of spline hole. 2. The maximum stress at the tangential direction (σ_θθ) is applied at the upper right boundary of spline hole. 3. The maximum shear stress (τrθ) in (-) direction is applied at the upper middle part of spline hole. 4. The maximum Mises stress is applied at the upper right boundary of spline hole. This stress is due to the critical stress by which rotor can be fractured according to elapsed time.

스위칭 파워 소모를 최소화하기 위한 마이크로 오퍼레이션 인코딩

성광수,현유진,정재국 嶺南大學校 工業技術硏究所 2004 工業技術硏究所論文集 Vol.32 No.1

In this paper, we propose an encoding algorithm for micro-operations which minimizes output transactions of control store. The transition rates between two micro-operations are computed based on the instruction usage frequency and the symbolic micro-codes of each instruction. Then, codes are assigned to micro-operations such that the Hamming distance of codes between micro-operations with higher transition rates is smaller. Experimental results on a x86 real mode symbolic micro-code set show that the proposed algorithm reduces the switching activity by 32% with only 6% area increase compared to the results of NOVA input encoding.

녹차 및 결명자 추출물의 교정용 브라켓과 치면 사이의 경계부에서 분리된 mutans streptococci에 대한 항균작용

임성훈,서정순,윤영주,김광원,유소영,김화숙,국중기,이병래,차종희,박재윤 대한치과교정학회 2003 대한치과교정학회지 Vol.33 No.5

본 연구는 치아우식증에 관련된 Mutans streptococci 표준균주 및 임상분리 균주의 성장억제를 유도할 수 있는 천연 생약추출물을 검색하기 위하여 실시되었다. 녹차추출물은 CHMC-2032를 사용하였으며, 결명자 추출물은 50% 에탄올을 이용하여 얻었다. 이들 추출물의 Mutans streptococci 표준균주 및 교정환자들에서 브라켓과 치면 사이의 경계부에서 분리된 각각 10 균주씩의 S. mutans 및 S. sobrinus에 대한 최소성장억제농도를 액체배지 희석법으로 구하였다. 그 결과 CHMC-2032의 S. mutans 및 S. sobrinus의 표준 균주, S. sobrinus의 대부분 임상분리 균주에 대한 최소성장억제농도는 5 mg/ml이었다. 그러나 결명자 추출물에 의한 S. mutans 및 S. sobrinus에 대한 세균 성장억제 효과는 미미하였다. 본 연구 결과 치아우식증의 예방적 측면에서 결명자차보다는 녹차를 마시는 것이 유리하며, CHMC-2032를 이용하여 구강양치용액을 제조하여 사용할 경우 교정환자를 포함하여 대부분의 사람에게서 치아우식증 예방 효과가 있으리고 추정된다. Mutans streptococci is the major causative factor in dental caries. Especially, orthodontic patients with fixed appliance are a risk group for dental caries. Because fixed appliances attached on teeth may change the environment of dental plaque, the enamel decalcification or dental caries around the bracket and band is a major side effect of orthodontic treatment. The aim of this study was to search plant extracts that have antimicrobial effect on mutans streptococci. Seed-extract of Casio tora were prepared with ethanol and CHMC-2032, the leaf-extracts from Camellia sinensis extract, was obtained extract, 2 type strains and 20 clinical isolates of mutans streptococci isolated from the interface between orthodontic brackets and tooth surfaces in the orthodontic patients were used in this study. The minimal inhibitory concentration of CHMC-2032 was 5 mg/ml on the S. mutans KCTC 3065, S. sobrinus KCTC 3088, and 8 clinical isolates of S. sobrinus. However, there was no antibacterial effect of seed-extract of C. tora on mutans streptococci. These data suggest that green tea may be more effective than the tea prepared from C. tora in the prevention of enamel decalcification or dental caries around brackets.

소장내 위석에 의한 장폐쇄증으로 발생한 급성신부전 1례

김승민,남지형,김준섭,이용국,최재혁,강혁주,탁우택,이정호,정호근 東國大學校醫學硏究所 2007 東國醫學 Vol.14 No.1

Gastric bezoars are concretions or hard masses of foreign matter found in the gastrointestinal tract. It may induce many complications including intestinal obstruction. No report has been proposed on a case of prerenal ARF induced by intestinal obstruction by small-bowel bezoar. Therefore, we report a case of the patient with ARF associated with small-bowel bezoar, who initially visited with the symptoms of nausea and frequent vomiting. 위석(bezoar)은 여러 가지 이물 및 내재성물질이 위장관내에서 혼합되어 응고물을 형성한 것을 말하며, 가장 흔한 형태의 합병증으로 장폐쇄증이 올 수 있으나, 그로 인하여 신부전의 양상으로 나타나는 경우는 흔하지 않다. 이에 저자들은 내원 당시의 병력 및 이학적 검사만으로 장폐색의 원인이 위석임을 의심할 수 없었던 비전형적인 소견을 보인 소장내의 위석에 의한 장폐쇄증과 이로 인해 발생한 급성신부전의 예를 경험하였기에 이에 보고하는 바이다.

한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

Design, Synthesis, and Biological Evaluation of Fluoroneplanocin A as the Novel Mechanism-Based Inhibitor of S-Adenosylhomocysteine Hydrolase

Jeong, Lak Shin,Yoo, Su Jeong,Lee, Kang Man,Koo, Mi Jeong,Choi, Won Jun,Kim, Hea Ok,Moon, Hyung Ryong,Lee, Min Young,Park, Jae Gyu,Lee, Sang Kook,Chun, Moon Woo 梨花女子大學校 藥學硏究所 2003 藥學硏究論文集 Vol.- No.12

Fluoroneplanocin A (12) was designed as a novel mechanism-based inhibitor of S-adenosylhomocysteine hydrolase (SAH) and efficiently synthesized via an electrophilic vinyl fluorination reaction (n-BuLi, N-fluorobenzenesulfonimide at -78℃). Fluoroneplanocin A exhibited 2-fold more potent SAH Inhibitory activity than the parent neplanocin A. A new mechanism of irreversible Inhibition discovered in this work might provide new alternatives in the design of a different class of antiviral agents operating via SAH inhibition.

흰쥐 심근에서 유리 지방산이 세포막 활동전위와 ATP-민감성 칼륨통로 활성에 미치는 영향

김재하,주정민,박종,백영홍,국현,정한성,정명호,조정관,박종춘,강정채 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.12