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강보라(Bo Ra Kang),김은희(Eun Hee Kim),김연경(Yeon Kyoung Kim),김아현(Ah Hhyun Kim),오규연(Gyu Yeon Oh),박유민(Yoo Min Park),조아현(Ah Hyeon Jo),나환식(Hwan Sik Na),신미영(Mi Yeong Shin),안양준(Yang Joon An),조정용(Jeong Yong Cho),이소 한국식품저장유통학회 2024 한국식품저장유통학회지 Vol.31 No.2
국화과에 속하는 큰비쑥은 ‘갯쑥’으로도 알려져 있는 염생식물로서 생물학적 이용 가능성이 높은 2차 대사산물이 풍부할 것으로 기대되며, 항염, 항산화, 미백효과 등 다양한 생리 활성이 있다고 알려져 있다. 따라서 본 연구에서는 큰비쑥을 경쟁력 있는 작물로써 이용성을 높이고자 생장 환경별 총폴리페놀 함량, 라디칼 소거능, 무기질 함량, 중금속 및 잔류농약을 분석하였다. 총폴리페놀은 가장 높은 함량을 보인 자생 성숙잎을 제외하고는 유의적인 차이가 없었으나(p<0.05), ABTS 및 DPPH 라디칼 소거능은 자생잎보다 재배잎에서 높은 활성을 보였다. 이는 폴리페놀 화합물의 구조적 요인이나 폴리페놀 화합물 이외의 영양성분들이 라디칼 소거능에 복합적으로 작용한 결과로 판단된다. 무기질 중 Na 함량은 자생 어린잎이 가장 높았으나, Na을 제외한 총 무기질 함량은 재배잎이 자생잎보다 높았다. K 및 Ca 함량은 자생잎보다 재배잎이 높았다. 큰비쑥 4종의 안전성을 알아보기 위해 중금속을 분석한 결과, Pb, Cd, As, Hg이 검출되었으나, 엽채류 식약처 고시 기준인 Pb 0.3 mg/kg, Cd 0.2 mg/kg보다 낮은 수준으로 나타났고 전반적으로 재배잎이 자생잎보다 낮게 측정되었다. 잔류농약은 큰비쑥 4종에서 검출되지 않아 안전하다고 판단된다. 결론적으로 본 연구를 통해 재배 큰비쑥은 전라남도 해안지역 자생 큰비쑥과 비교하여 큰 차이가 없어 재배잎을 육종하여 대량생산한다면 이용 가능성이 높은 품종으로 활용 가능하다고 판단된다. Artemisia fukudo Makino belongs to the Asteraceae family, is a halophyte that can grow in salinity soils and is known for its various physiological activities. However, few studies were comparing it according to the growth environment. Therefore, in this study, we analyzed the antioxidant activity, functional ingredients, and safety of Artemisia fukudo Makino according to the growth environment. Total polyphenol content was the highest in native mature leaves, but 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) and 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity was higher in cultivated leaves than in native leaves. The total mineral content, excluding sodium, was higher in cultivated than in native leaves. The content of potassium and calcium was higher in cultivated leaves than in native leaves. In addition, heavy metal analysis showed that cultivated leaves were generally lower than those of native leaves. Residual pesticides were not detected in all samples. In conclusion, since there is no significant difference in cultivated leaves compared to native leaves, it was judged that cultivated leaves could be used as a variety to be grown and mass-produced.
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A Case of Idiopathic Aortitis with Left Renal Vein Thrombosis
Hyeon Jeong Yun,Jin Uk Jeong,Jong Ho Shin,Jin Ho Choi,Young Min Na,Jin Cheol Myeong,Ki Tae Bang 순천향대학교 순천향의학연구소 2014 Journal of Soonchunhyang Medical Science Vol.20 No.2
A 38-year-old man was admitted to the hospital because of abrupt left flank pain. He had no fever and physical examination revealed tenderness of the left costovertebral angle. Laboratory data revealed white blood cell 16,060/μL, C-reactive protein 0.93 mg/ dL. Urinalysis showed more than 1/2 red cells per high-power field with severe proteinuria (4+). Enhanced computed tomography (CT) showed the thickened abdominal aorta wall with partial thrombus. The thickened aorta wall compressed the left renal vein and it caused left renal vein thrombosis. Abdominal CT findings suggested aortitis of the abdominal aorta with complication of left renal vein. We could exclude other types of aortitis including autoimmune aortitis, Takayasu’s arteritis, giant cell arteritis, and infectious causes based on a serologic test and the history of the patient. Therefore, the patient was diagnosed with idiopathic aortitis and treated with glucocorticoid. After treatment, his symptoms disappeared and a follow-up CT showed decreased mural thickening of the abdominal aorta. Isolated idiopathic aortitis presented with renal vein thrombosis is extremely rare and has not been reported in Korea yet. We present a rare case report on idiopathic aortitis of the abdominal aorta with complication of left renal vein thrombosis.
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Reproductive and Developmental Toxicity of Amitraz in Sprague-Dawley Rats
Jeong-Hyeon Lim,Sung-Hwan Kim,Kang-Hyeon Kim,Na-Hyeong Park,In-Sik Shin,Changjong Moon,Soo-Hyun Park,Sung-Ho Kim,Jong-Choon Kim 한국독성학회 2010 Toxicological Research Vol.26 No.1
The present study was conducted to obtain information on the effects of amitraz on reproductive and developmental parameters in rats. The test chemical was administered via the drinking water containing 0, 40, 120, and 360 ppm to male rats from 2 weeks before mating to the end of 14-day mating period and to females from 2 weeks before mating, throughout mating, gestation and up to lactational day 4. During the study period, clinical signs, body weights, food intake, organ weights, reproductive and littering findings, necropsy findings, sperm parameters, and histopathology were examined. At 360 ppm, decreases in the body weight gain, food consumption, and the number of live pups and an increase in the post-implantation loss were observed. In addition, decreases in the seminal vesicle weight and sperm motility were found in males. At 120 ppm, a decrease in the food consumption was found transiently in both males and females, but no reproductive and developmental toxicity was observed in both sexes. There were no signs of either general or reproductive and developmental toxicity in the 40 ppm group. Based on these results, it was concluded that the repeated oral administration of amitraz to rats resulted in a decrease in the food consumption at 120 ppm and decreases in the seminal vesicle weight, sperm motility, and the number of live pups and an increase in the post-implantation loss at 360 ppm in rats. Under these experimental conditions, the no-observed-adverse-effect level (NOAEL) of amitraz for general and reproduction/developmental toxicity was believed to be 120 ppm, and the no-observed-effect level (NOEL) of amitraz was believed to be 40 ppm in rats.
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The Suitability Assessment for Recycling Inorganic Wastes in Korea
( Na-hyeon Cho ),( Mi-jeong Jeong ),( Min-jung Kim ),( Young-yeul Kang ),( Soo-youn Hong ),( Cheol-woo Yoon ),( Sun-kyoung Shin ),( Ki-heon Kim ) 한국폐기물자원순환학회(구 한국폐기물학회) 2019 ISSE 초록집 Vol.2019 No.-
As of July 21, 2016, the Ministry of Environment in Korea introduced and enforced the Environmental Assessment of Recycling (EAoR) system for effective waste management and the reduction of environmental burden of recycled products. On the basis of the purpose of EAoR system, Recycling methods and assessment items for non-matrix/matrix contact recycled products are investigated including the management about leaching toxicity and the concentration of hazardous materials in designated wastes. However, there is growing concerns about environmental/human health issue with regard to the recycling of inorganic wastes; High concentration of hexavalent chromium was detected from landfill cover material recycling ferro-silt in Japan, phenol detected from waste foundary sand and arsenic detected from the sludge in water treatment plant. In this study, the sludges discharged from water treatment plant and waste foundry sands in Korea are investigated to evaluated the suitability for matrix contact recycling of inorganic wastes in Korea. sludge and sands samples are collected to investigate the hazardous substances affecting environment and human health. This study introduce the physical, chemical properties of inorganic waste and various leachate test methods including up-flow permeability test designed to simulate the flow of percolating groundwater through a porous bed of granular material.
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Reproductive and Developmental Toxicity of Amitraz in Sprague-Dawley Rats
Lim, Jeong-Hyeon,Kim, Sung-Hwan,Kim, Kang-Hyeon,Park, Na-Hyeong,Shin, In-Sik,Moon, Chang-Jong,Park, Soo-Hyun,Kim, Sung-Ho,Kim, Jong-Choon Korean Society of ToxicologyKorea Environmental Mu 2010 Toxicological Research Vol.27 No.1
The present study was conducted to obtain information on the effects of amitraz on reproductive and developmental parameters in rats. The test chemical was administered via the drinking water containing 0, 40, 120, and 360 ppm to male rats from 2 weeks before mating to the end of 14-day mating period and to females from 2 weeks before mating, throughout mating, gestation and up to lactational day 4. During the study period, clinical signs, body weights, food intake, organ weights, reproductive and littering findings, necropsy findings, sperm parameters, and histopathology were examined. At 360 ppm, decreases in the body weight gain, food consumption, and the number of live pups and an increase in the post-implantation loss were observed. In addition, decreases in the seminal vesicle weight and sperm motility were found in males. At 120 ppm, a decrease in the food consumption was found transiently in both males and females, but no reproductive and developmental toxicity was observed in both sexes. There were no signs of either general or reproductive and developmental toxicity in the 40 ppm group. Based on these results, it was concluded that the repeated oral administration of amitraz to rats resulted in a decrease in the food consumption at 120 ppm and decreases in the seminal vesicle weight, sperm motility, and the number of live pups and an increase in the post-implantation loss at 360 ppm in rats. Under these experimental conditions, the no-observed-adverse-effect level (NOAEL) of amitraz for general and reproduction/developmental toxicity was believed to be 120 ppm, and the no-observed-effect level (NOEL) of amitraz was believed to be 40 ppm in rats.
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나현숙(Na, Hyeon-Suk),정상혁(Jeong, Sanghyeok),정주홍(Jeong, Juhong) 한국게임학회 2015 한국게임학회 논문지 Vol.15 No.4
스텔스 게임 레벨 디자이너는 다양한 난이도의 흥미로운 게임환경(레벨)을 제작해야 한다. J. Temblay와 공동 연구자들은 이 과정의 자동화를 돕는 Unity-기반 레벨 디자인 툴을 개발했다. 이 툴은 디자이너가 지도에서 경비병의 경로, 속도, 감시 영역, 플레이어의 출발점과 도착점 등 여러 게임 요소들을 입력하면 플레이어가 취할 수 있는 가능한 경로들을 포함한 다양한 시뮬레이션 결과들을 보여준다. 이를 이용해 디자이너는 현재의 게임 요소들이 자신이 의도한 난이도 및 플레이어 경로를 만드는지 실시간으로 확인할 수 있고, 필요한 경우 이들을 조정할 수 있게 되었다. 여기서는 두 가지 면에서 이 툴의 개선점을 제시한다. 첫째, 디자이너가 몇 개의 지점을 입력하면 이 지점들을 포함하는 흥미로운 경비병의 감시 경로를 난이도별로 추천해주는 기능을 추가해서 레벨 디자인 툴로서의 편의성과 유용성을 높였다. 둘째, 기존의 충돌 체크 함수 및 RRT-기반 경로 탐색 함수를 새로운 충돌 체크 함수와 델로네 로드맵-기반 경로 탐색 함수로 대체하여 시뮬레이션 속도를 크게 향상시켰다. In the stealth game design, level designers are to develop many interesting game environments with a variety of difficulties. J. Tremblay and his co-authors developed a Unity-based level design tool to help and automate this process. Given a map, if the designer inputs several game factors such as guard paths and velocities, their vision, and the player's initial and goal positions, then the tool visualizes simulation results including (clustered) possible paths a player could take to avoid detection. Thus with the help of this tool, the designer can ensure in realtime if the current game factors result in the intended difficulties and players paths, and if necessary adjust the factors. In this note, we present our improvement on this tool in two aspects. First, we integrate a function that if the designer inputs some vertices in the map, then the tool systematically generates and suggests interesting guard paths containing these vertices of various difficulties, which enhances its convenience and usefulness as a tool. Second, we replace the collision-detection function and the RRT-based (player) path generation function, by our new collision-check function and a Delaunay roadmap-based path generation function, which remarkably improves the simulation process in time-efficiency.
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