창의성 관점에서 본 제 7차 초등 수학과 교육과정 : 규칙성과 함수를 중심으로 Focusing on Patterns and Functions

서경혜,유솔아,정진영 한국수학교육학회 2003 初等 數學敎育 Vol.7 No.1

The present study examined the 7th national elementary school mathematics curriculum from a perspective of mathematical creativity. The study investigated to what extent the activities in the Pattern and Function lessons in the national elementary school mathematics textbooks promoted the development of mathematical creativity. The results indicated that the current elementary school mathematics curriculum was limited in many ways to promote the development of mathematical creativity. Regarding the activities in Pattern lessons, for example, most activities presented closed tasks involving finding and extending patterns. The lesson provided little opportunities to explore the relationships among various patterns, apply patterns to different situations, or create ones own patterns. In regard to the Function lessons, the majority of activities were about computing the rate. This showed that the function was taught from an operational perspective, not a relational perspective. It was unlikely that students would develop the basic understanding of function through the activities involving the computing the rate. Further, the lessons had students use exclusively the numbers in representing the function. Students were provided little opportunities to use various representation methods involving pictures or graphs, explore the strengths and limitations of various representation methods, or to choose more effective representation methods in particular contexts. In conclusion, the lesson activities in the current elementary school mathematics textbooks were unlikely to promote the development of mathematical creativity.

Application of microwave for the production of ghost probiotics with concentrated Lactobacilli cells

Gyeong-Jun NAM,Jong-Hun HAN,Yun-Jeong YANG,Hye-In SEOL,Hye-Jin KIM,Hye-Jin LEE,Byung-Chun KIM,Vivek K. BAJPAI,Sung-Chul SONG,Jong-Hwan LEE,Yong-Ha PARK 한국생물공학회 2016 한국생물공학회 학술대회 Vol.2016 No.4

Up-to-Date Knowledge on Osteoporosis Treatment Selection in Postmenopausal Women

Hye Gyeong Jeong,Min Kyung Kim,Hee Jeung Lim,Seul Ki Kim 대한폐경학회 2022 대한폐경학회지 Vol.28 No.3

The concept of a super-aged society has led to a steady increase in the average lifespan and hence, interest in a healthy life has increased. Aging is a major risk factor for many diseases, including osteoporosis. Osteoporotic fractures have a significant impact on the quality of life of the elderly and hence, it is pivotal to provide effective treatment of osteoporosis after menopause. Osteoporosis requires proper management and the treatment must be centered on long-term goals. New drugs with diverse mechanisms have been developed for treating osteoporosis. Current management of osteoporosis generally focuses on the importance of risk-based strategies to maximize the effectiveness of existing treatments and mitigate potential negative side-effects. Additionally, there is a need for sequential treatment of osteoporosis in the future. This review discusses the dynamic strategies for osteoporosis treatment and the importance of long-term management in postmenopausal women.

Genetic causal relationships between the age at menarche and menopause on the susceptibility to breast and uterine cancer in East Asian women

( Hye Gyeong Jeong ),( Su Min Kang ),( Su Min Cho ),( Charise Mae Malabanan ),( Ki-jin Ryu ),( Tak Kim ),( Yoonjung Yoonie Joo ),( Hyuntae Park ) 대한산부인과학회 2023 대한산부인과학회 학술대회 Vol.109 No.-

review : Role of intestinal microflora in xenobiotic-induced toxicity

( Hye Gwang Jeong ),( Mi Jeong Kang ),( Hyung Gyun Kim ),( Do Gyeong Oh ),( Jin Sung Kim ),( Sang Kyu Lee ),( Tae Cheon Jeong ) 영남대학교 약품개발연구소 2013 영남대학교 약품개발연구소 연구업적집 Vol.23 No.0

In addition to its role in digestion of food in the gastrointestinal tract, the intestinal microflora is also capable of biotransforming numerous drugs. Likewise, the intestinal microflora may significantly modulate xenobiotic-induced toxicity by either activating or inactivating xenobiotics via metabolism. To date, most investigations of xenobiotic metabolism have focused not only on metabolism in host tissues, but the modulation of the pharmacological activity of drugs by the intestinal microflora. Despite its importance, the presumed role of intestinal microflora metabolism inxenobiotic-induced toxicity has been understudied. Therefore, it is appropriate to briefly review our current situation, and state which research in xenobiotic metabolism by intestinal microflora, particularly in the field of toxicology, is needed.

Correlation of oocyte number with serum anti-Müllerian hormone levels measured by either Access or Elecsys in fresh in vitro fertilization cycles

Jeong, Hye Gyeong,Kim, Seul Ki,Lee, Jung Ryeol,Jee, Byung Chul The Korean Society for Reproductive Medicine 2022 Clinical and Experimental Reproductive Medicine Vol.49 No.3

Objective: The aim of this study was to assess the correlation of oocyte number with serum anti-Müllerian hormone (AMH) levels measured by two automated methods (Access or Elecsys) in fresh stimulated in vitro fertilization (IVF) cycles. Methods: In this retrospective study at a university hospital, data were collected from 243 fresh stimulated IVF cycles performed from August 2016 to December 2020. The serum AMH level was measured by Access in 120 cycles and by Elecsys in 123 cycles. The cut-off of serum AMH for prediction of poor responders (three or fewer oocytes) or high responders (15 or more oocytes) was calculated by the receiver operating characteristic curve analysis. Results: For the two automated methods, the following equations were derived: total oocyte number=2.378+1.418×(Access-AMH) (r=0.645, p<0.001) and total oocyte number=2.417+2.163×(Elecsys-AMH) (r=0.686, p<0.001). The following combined equation could be derived: (Access-AMH)=0.028+1.525×(Elecsys-AMH). To predict poor responders, the cut-off of Access-AMH was 1.215 ng/mL (area under the curve [AUC], 0.807; 95% confidence interval [CI], 0.730-0.884; p<0.001), and the cut-off of Elecsys-AMH was 1.095 ng/mL (AUC, 0.848; 95% CI, 0.773-0.923; p<0.001). To predict high responders, the cut-off of Access-AMH was 3.450 ng/mL (AUC, 0.922; 95% CI, 0.862-0.981; p<0.001), and the cut-off of Elecsys-AMH was 2.500 ng/mL (AUC, 0.884; 95% CI, 0.778-0.991; p<0.001). Conclusion: Both automated methods for serum AMH measurement showed a good correlation with oocyte number and good performance for predicting poor and high responders in fresh stimulated IVF cycles. The Access method usually yielded higher measured serum AMH levels than the Elecsys method.

Simple nanophotosensitizer fabrication using water-soluble chitosan for photodynamic therapy in gastrointestinal cancer cells

Jeong, Young-IL,Cha, Byungyoul,Lee, Hye Lim,Song, Yeon Hui,Jung, Yun Hye,Kwak, Tae Won,Choi, Changyong,Jeong, Gyeong-Won,Nah, Jae Woon,Kang, Dae Hwan Elsevier/North Holland 2017 International journal of pharmaceutics Vol.532 No.1

<P><B>Abstract</B></P> <P>The polysaccharide chitosan has abundant cationic amine groups, and can form ion-complexes with anionic molecules such as the strong photosensitizer chlorin e6 (Ce6). In this study, water-soluble chitosan (WSC) was used to fabricate Ce6-incorporated nanophotosensitizers (Abbreviated as ChitoCe6 nanophotosensitizer) via a self-assembling process. This was accomplished by dissolving WSC in pure water and then directly mixing the solution with solid Ce6 causing ion complex formation between WSC and Ce6. The resulting nanophotosensitizer was spherical in shape and had a particle size of less than 300nm. The photodynamic effect of ChitoCe6 nanophotosensitizer was evaluated using gastrointestinal (GI) cancer cells. At <I>in vitro</I> study using SNU478 cholangiocarcinoma cells, ChitoCe6 nanophotosensitizer showed improved Ce6 uptake by tumor cells, reactive oxygen species production, and cellular phototoxicity. An <I>in vivo</I> study using SNU478-bearing nude mice showed that the ChitoCe6 nanophotosensitizer efficiently accumulated in the tumor tissue and inhibited tumor growth more than treatment with Ce6 alone. Furthermore, ChitoCe6 nanophotosensitizer was also efficiently absorbed through tissue layers in an <I>ex vivo</I> study using porcine bile duct explants. ChitoCe6 nanophotosensitizer showed enhanced photosensitivity and photodynamic effects against cancer cells <I>in vitro</I> and <I>in vivo</I>. We present ChitoCe6 nanophotosensitizer as a promising candidate for photodynamic therapy of GI cancer.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

The Largest Uterine Leiomyoma Removed by Robotic- Assisted Laparoscopy in the Late Reproductive Age: A Case Report

( Hye Gyeong Jeong ),( Min Jung Lee ),( Jung Ryeol Lee ),( Byung Chul Jee ),( Seul Ki Kim ) 대한폐경학회 2021 대한폐경학회지 Vol.27 No.1

Uterine leiomyoma is a very common gynecological tumor in the reproductive years. Recent studies have shown that surgical treatment of uterine leiomyoma using robotic-assisted laparoscopic myomectomy (RALM) is associated with significantly fewer complications, lower estimated blood loss, fewer conversions, and less bleeding than conventional laparoscopic myomectomy. This study reports the case of a giant uterine leiomyoma treated using RALM. A 50-year-old woman was referred to our outpatient clinic with progressive abdominal distension. Ultrasonography and magnetic resonance imaging were performed and showed a markedly enlarged uterus containing a 28-cm uterine myoma. RALM confirmed the 28-cm subserosal myoma on the posterior wall of the uterus. The myoma was enucleated, and the myometrial and serosal defect was repaired with a continuous suture using barbed suture materials. The entire myoma was removed using an electric morcellator. The operation lasted for 190 minutes. The total weight of the removed myoma was 3,262 g, and uterine leiomyoma was pathologically diagnosed. There were no postoperative complications. Although the treatment of huge myomas using RALM is controversial and technically demanding, we successfully performed RALM in a patient with a large myoma. This case confirms the efficiency, reliability, and safety of a robotic-assisted laparoscopic approach for removing a huge myoma. In a well-selected case, RALM can be performed by experienced surgeons regardless of the size of fibroids.

대장내시경 전처치에서 Midazolam 단독 투여와 Midazolam과 Meperidine의 병용 투여의 비교에 관한 연구 전향적, 무작위 추출, 이중맹검법

정혜경 ( Jeong Hye Gyeong ),배기선 ( Bae Gi Seon ),윤수진 ( Yun Su Jin ),이종수 ( Lee Jong Su ),권정미 ( Kwon Jeong Mi ),유민아 ( Yu Min A ) 대한소화기학회 2004 대한소화기학회지 Vol.43 No.2

Background/Aims: Colonoscopy is a painful procedure. Therefore conscious sedation is often used. However, the value of adding analgesics to sedatives has not been well evaluated. Methods: The double blind, randomized controlled trial was carried out to compare patients` and endoscopist` assessments in both groups of patients: MP (Midazolam/Placebo) group (n=49) received midazolam plus placebo and MM (Midazolam/Meperidine) group (n=51) received midazolam plus meperidine. Results: There was no significant difference of baseline characteristics except previous operation history. There were no significant difference of grade of tolerance, pain and willingness to another colonoscopy between the two groups. In endoscopist` satisfaction, the degree of difficulty was higher in MP group than in MM group (39.0 vs. 31.7, p<0.05). After the colonoscopy, systolic blood pressure, oxygen saturation, and pulse rate were significantly decreased (p<0.05) in both groups. However, there was no difference in the degree of decrease between the two groups. The incidence of adverse effect was not different in the two groups. However, one case of orthostatic hypotension with presyncope was noted in MM group. Conclusions: Adding meperidine to the midazolam before the colonoscopy does not seem to bring more beneficial effect to patients, whereas endoscopist favored the use of both medications. (Korean J Gastroenterol 2004; 43:96-103)

한국 현대소설에 나타난 여성정체성의 변모과정연구 -남성 인물의 시선에 비친 여성을 중심으로-(1990-2000이후)

정혜경 ( Hye Gyeong Jeong ) 문창어문학회 2008 문창어문논집 Vol.45 No.-

Examining female characters appearing in modern Korean novels together with the circumstances of the time and tracing the past and present issues of women identities is for presenting a direction of life for true coexistence for both men and women. The reason for aiming for this dual-gender culture is for developing the potential women identity and to fill the areas that are deficient due to the male centered culture. This kind of study will be able to sufficiently refill the distorted and empty culture of humankind and also be a driving force that promotes new creativity. Realistically, the existing language that is equipped with the time-old social experience of men and its accompanying acquisition rights may be perceived to be mostly consistent with world history. The objective of this paper is to track these differences and to make this an opportunity to realize that women issues are not the problems of others, but are issues that should be resolved through the collaboration of both men and women. Books used for research in this study are those written from 1990 to post 2000 that properly reflect the circumstances of the era and were convenient to examine the women identity issues of the time. The studies were conducted by examining the women`s identity by tracing the actual perception issues of women that were perceived by the male characters in the works per time period. Coming into the 1990s, women became more vocal and in the changing social systems, there were many changes in the status of women. However, books written during this period show that the mind sets of men were still steadfast through their female characters. Unlike men who protest that they incurred damages from women but do not realize their selfishness, women who made their own selfish yet reasonable selections were formed. It also creates women who contemplate their identity issues and desire for a new family. These situations are accelerated by the appearance of women who seek to find relief from their oppressions and discriminations through sisterhood-like relations. Furthermore, the attitude of women responding to their husbands` whoring changed rapidly as well and they show an assertiveness to heal their own wounds and hurts. Since 2000, there is an even faster change of these circumstances. A new breed of women appeared that chose to be wicked women so that they could live a life where they as women were the center of their lives. Female characters are distinguished based on several contexts. Wicked women in novels do not exercise violence, but survives and pays revenge through disguises. This issue with disguise is related to the indeterminacy of female genders. Through disguise and discourse weapons of disguise, the women reveal their secret desires. First-person women speakers in the works are in the form of a type of disguised speaker, rather than a confessor. This disguise, or makeup, is possible through the double strategy of discourse. In order to live in this society and system, the writer ``disguises`` the ``female identity`` and express their ``disguise`` through camouflaged discourse. It is a tragedy that female characters in this age still have to exercise ``provocative lives``. This is because it shows the current situation where manly hypocrisy and stoicism is still surging in a paradoxical fashion. However, no matter what the circumstances are, the efforts of women to pioneer unfamiliar and difficult paths without hesitating or stopping will continue in various ways. The journey as a wicked woman is rough and dangerous and it is accompanied with realistic difficulties of having to persevere through a great number of resistances. We should, however, pay heed to the fact that new questions are being asked on everyday values that reveals and exposes the importance of the daily lives and desires of women. Straying from the male-centered mechanism that attempts to commodities not only women, but even history, and to be vigilant against the dangerous desires; if hypocrisies and oppressions in life exist, it is the writer`s job and there reason for existence to reveal them. Confrontations only cause destruction for both sides. Being vigilant rather than antagonistic may seem to bring about chaos. However, vigilance can be the driving force to reach a new society filled with the creativity and possibilities to move into a new world that has yet been seen. From this point of view, this study that examines the identity issues of women per time period according to the perspectives of male characters will be significant for searching for a future with room for development.