全蝎 抽出物이 血栓症, 全腦虛血 및 腦細胞毒性에 미치는 影響

백명현,황영근,정지천,강정준,김성훈 동국대학교 한의학연구소 1999 東國韓醫學硏究所論文集 Vol.8 No.1

본 실험은 전갈 추출물이 어혈병태 모델과 KCN으로 유발된 전뇌허혈, 뇌세포독성 등에 미치는 영향을 관찰하였다. 전갈은 Dextran에 의해 유도된 혈전으로 감소된 혈소판수, fibrinogen량, hemocrit치를 유의성 있게 증가시키고. 증가된 prothrombin time을 유의성 있게 단축시켰다. 전갈은 thrombin과 ADP에 의해 유도된 혈소판 응집을 억제하였으나 collagen에 의해 유도된 혈소판 응집에는 저해효과를 나타내지 않았다. 또한 collagen과 epinephrine에 의해 유도된 pulmonary embolism에 대하여 보호 효과를 나타내었다. 전갈은 KCN에 의한 전뇌허혈 유발 실험에서 혼수시간을 유의성 있게 단축시켰고, Amyloid β protein(25-35)에 의해 유도된 PC12 세포의 독성에 대하여 보호효과를 나타내었다. This following is effect of Buthus martensi Karsch (BMK) extract on dextran-thrombus model, KCN-induced coma, cytotoxicity of brain etc. BMK extract significantly increased number of platelet and fibrogen and significantly shortened the prothrombin time as compared with control group treated with dextran. BMK extract didn't affect the changes of hematocrit as compared with control group treated with dextran. BMK extract induced a significant inhibition of human platelet aggregation induced by thrombin and ADP but did not affect human platelet aggregation induced by collagen. BMK extract showed a protective effect on pulmonary thrombosis induced by collagen and epinephrine. BMK extract prolonged the duration of KCN-induced coma and showed a protective effect on cytotoxicity of PC12 cells induced by amyloid β protein(25-35) in a dose dependent manner. These results suggested that BMK extract might be usefully applied for prevention and treatement of thrombosis and brain damage.

성악골 절제후 유리피판술을 이용한 상악재건 3례 보고

박정일,한태근,최준,백세민 大韓成形外科學會 1991 Archives of Plastic Surgery Vol.18 No.1

Malignant tumor of the head and neck can be treated by radical excision of the lesion. But the resultant facial deformity acts as a handicap in the patient's life. The quality of life is as important as the quantity. Therefore reconstruction of these patients is an important field in plastic surgery. We used 3 kinds of flap for reconstruction after maxillectomy. Two cases were late reconstruction with Rectus Abdominis myocutaneous free flap and parascapular free flap respectively. In remaining one case, immediate reconstruction was performed with rib bone graft and Latissimus Dorsi free flap. The results were satisfactory. But we found that ptosis of the flap is problem in all cases.

한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

신뢰수준으로 측정한 사회적 자본과 암 검진 수검 간의 관계

정백근(Baek-Geun Jeong),황인경(In-Kyoung Hwang),손혜숙(Hae-Sook Sohn),고광욱(Kwang-Wook Koh),윤태호(Tae-Ho Yoon),임정훈(Jeong-Hun Lim) 한국보건교육건강증진학회 2011 보건교육건강증진학회지 Vol.28 No.2

Objectives: This study was conducted to investigate the relationships between trust and participation in cancer screening. Methods: Data from 2004 Busan Health Survey were analysed for the study. Multiple logistic regression was performed on participation in cancer screening by trust level with potential confounders(sex, age, education, monthly mean household income, subjective health status, smoking, alcohol intake, exercise, and daily eating habits). Results: In a total of 7,423 participants, 2,078(28.0%) were classified as cancer screening participants. High horizontal trust was associated with increased likelihood of cancer screening participation(OR(men) = 1.20, 95% CI 1.00-1.45) and (OR(women) = 1.19, 95% CI 1.02-1.39), after multiple adjustments. Respondents with high trust in health care system had significantly higher odds ratios for participation in cancer screening: 1.60(95% CI 1.27-2.02) among men and 1.18(95% CI 0.97-1.44) among women, after multiple adjustments. Conclusions: Trust was significantly associated with higher odds of cancer screening participation and could be a potent arena for increasing cancer screening participation.

보건의료체계에 대한 신뢰도와 건강검진 수진율 간의 관계

정백근(Baek Geun Jeong),황인경(In-Kyoung Hwang),손혜숙(Hae-Sook Sohn),고광욱(Kwang Wook Koh),윤태호(Tae-Ho Yoon),임정훈(Jeong-Hun Lim) 한국농촌의학 지역보건학회 2010 농촌의학·지역보건 Vol.35 No.4

본 연구는 건강검진 수검과 보건의료체계에 대한 신뢰 수준 간의 관계를 파악하기 위하여 수행된 연구로서 2004년 부산시민 건강조사에 참가한 만 20세 이상 7,683명을 대상으로 하였다. 그 결과 남성과 50대 연령층의 건강검진 수진율이 높았으며 교육수준과 소득수준, 수평적 신뢰수준이 높을수록, 주관적 건강상태가 좋지 않을 수록 수진율이 증가하였다. 또한 보건의료체계에 대한 신뢰도가 높은 사람들이 낮은 사람들에 비하여 건강검진을 받을 확률이 높았다 향후 국민들의 보건의료체계에 대한 신뢰도에 영향을 미칠 수 있는 요인들을 파악하고 이러한 요인들이 국민들의 건강검진 수진율에 영향을 미치는 경로를 파악한다면 국민 보건에 이바지할 수 있는 다양한 방안들이 마련될 수 있을 것으로 판단된다. Objectives: This study was conducted to investigate the relationship between vertical trust in the healthcare system and participation in routine health examinations. Method: Data from the 2008 Pusan Health Survey were analyzed for this study. Multiple logistic regression analyses were performed to investigate the influence of possible confounders (sex, age, education, monthly mean household income, horizontal trust) on participation in routine health examinations according to trust in the healthcare system. Result: In a total sample of 7,683 participants, 3,756 (48.9%) were classified as health examination participants. Respondents with high trust in the healthcare system had significantly higher odds ratios of participation, 1.17 (95% CI 1.03-1.33), after multiple adjustments. Conclusion: Vertical trust in the healthcare system was significantly associated with higher odds of participation in routine health examinations. Improvements to the healthcare system have potential for increasing participation in routine health examinations.

〈사례보고〉 경상남도 지역 간 건강불평등 완화사업

정백근(Baek Geun Jeong),김장락(Jang-Rak Kim),강윤식(Yune-Sik Kang),박기수(Ki-Soo Park),이진향(Jin Hyang Lee),조선래(Sun-Rae Jo),서기덕(Gi-Deok Seo),주상준(Sang-Jun Joo),오은숙(Eun-Suk Oh),김승진(Seung-Jin Kim),조성진(Seong-Jin Jo),김승 한국농촌의학 지역보건학회 2012 농촌의학·지역보건 Vol.37 No.1

‘건강 플러스 행복 플러스 사업’은 경상남도의 높은 표준화사망률을 감소시키고 지역 간 건강불평등을 완화하기 위하여 표준화사망비가 구조적으로 높은 40개 읍면동을 대상으로 수행되는 사업이다. 본 사업은 영국의 헬스 액션 존 사업의 방법론을 기반으로 하여 참여, 파트너쉽, 자원의 집중을 사업의 기본 원칙으로 설정하고 2010년부터 시작되었으며 2017년까지 진행될 예정이다. 총사업비는 56억원이며, 2010년에는 17개 읍면동, 2011년에는 12개 읍면동, 2012년에는 11개 읍면동에 사업이 개시되었거나 개시될 예정이다. 2010년 사업의 경우, 사업대상지역인 17개 읍면동에 예산이 배정되었고, 관련 수단 및 지역 차원의 사업진행 틀을 만드는 과정을 거쳤다. 또한 사업대상지역의 건강결정요인을 파악하기 위하여 지역사회조사를 실시하였으며 사업에 대한 교육훈련지원 및 기술지원을 위하여 교육훈련지원단과 사업운영지원단이 설치되었다. 그 결과 사업 인력들과 코디네이터에 대한 교육이 실시되었으며, 사업대상지역에는 사업팀과 사업추진위원회가 결성되었다. 지역사회조사 이후에는 지역사회조사 결과 보고회를 통하여 지역의 건강결정요인과 건강수준을 지역주민들과 함께 공유하였으며 최종적으로 사업 관련 주민자치조직인 건강위원회가 17개 읍면동에서 출범하였다. 본 사업은 지역사회 참여 및 파트너쉽의 구축과 관련하여 아직 해결해야 될 과제들이 많으나 원칙에 근거한 사업이 지속적으로 진행될 수 있다면 경상남도의 건강불평등 완화를 통한 표준화사망률 감소 및 사업대상지역 주민들의 안녕 수준 향상에 기여할 수 있을 것으로 판단된다. Objectives: This study was conducted to implement Health Plus Happiness Plus projects in Gyeongsangnam-Do and assess the policy implications of initiatives to address regional health inequalities. Methods: Health Plus Happiness Plus projects were started as strategies to address regional health inequalities in Gyeongsangnam-Do. The principles of these projects are taken from the Health Action Zones initiatives in England: participation, partnership, resource concentration in project areas. The time period for these projects is from 2010 to 2017, and the total budget is 5.6 billion won. In 2010, a 6.8 hundred million won total budget was invested in 17 project areas. Such investments fell into four broad categories: establishment of the means and local framework; survey development to analyze the health determinants; development of an education and training center; and establishment of a technical support center. Results: Education and training programs for practitioners and coordinators were provided, and project teams and project promotion committees were established in project areas. Health survey result briefing meetings were held, and 17 health committees were established in project areas. Conclusions: Health Plus Happiness Plus projects have some problems in relation to participation and partnerships, however, if these principled projects are performed continuously, they will contribute to a reduction of standardized mortality rate and regional health inequalities in Gyeongsangnam-Do and the improvement of residents’ well-being in project areas.

병원급 의료기관 의사 1인당 일일 진료환자 수와 관련요인

정백근 ( Baek Geun Jeong ),이상이 ( Sang Yi Lee ) 한국병원경영학회 2002 병원경영학회지 Vol.7 No.2

The purpose of this paper is to find the factors affecting the number of patients per physician for a day at hospital and compare them with the results of previous studies. We used data of Korean national patients survey that had been carried out by central government and local health centers from October 27th to November 11th in 1999. Descriptive analyses were performed to overview the general characteristics of our study subject. Also, we tried to find the factors affecting the number of patients per physician for a day at hospital through t test and correlation analysis. Factors affecting the number of outpatients per physician for a day at hospital are location, training type, ownership, No. of physicians, No. of beds per physician, No. of pharmacists per physician, No. of nursing aids per physician and No. of medical techcians per physician. W e factors affecting the number of inpatients per physician for a day at hospital are location, ownershp, No. of physicians, No. of beds per physician, No. of pharmacists per physician, No. of nurses per physician, No. of nursing aids per physician and No. of administrative awullary personnels per physician. The most correlated variable with outpatients per physician for a day at hospital is No. of medical techcians per physician whde the most correlated variable with inpatients per physician for a day at hospital is No. of beds per physician. A more detailed investigation is needed for verifying factors affecting the number of patients per physician for a day at hospital and other medical institutions.

사회경제적 지위와 사회적 관계가 우울에 미치는 영향

정백근(Baek Geun Jeong) 한국보건교육건강증진학회 2016 보건교육건강증진학회지 Vol.33 No.5

Objectives: This study was to examine the independent and mediating effect of socioeconomic position and social relationship on depression. Methods: The study analyzed the data from the 2014 Korea Welfare Panel Study(n=9,172) using descriptive statistics, Kendall’s rank correlation analysis, multiple regression analysis and the Sobel test. Results: Much of the connection between parental socioeconomic position and respondent depression was explained by respondent educational attainment in men but was not in women. A large portion of the association between educational attainment and depression was explained by type of household and satisfaction with social relationship among men. The effect of educational attainment on depression was fully mediated by type of household among women. The effect of type of household on depression was partly mediated by satisfaction with social relationship in men and women. Lastly, educational attainment, type of household and satisfaction with social relationship had an independent association with depression among men, but educational attainment was not statistically significant among women. Conclusions: Our study illuminated the importance of the independent and mediating effect of parental and respondent socioeconomic position and social relationship in the production of depression for South Korean adults.

Stepper-based L_g = 0.5 μm In_0.52Al_0.48As/In_0.7Ga_0.3As PHEMTs on a 3-inch InP substrate with record product of f_T and L_g

Baek, Ji-Min,Son, Seung-Woo,Park, Jung Ho,Park, Jong-Keun,Kwak, Jeong-Geun,Yoon, Jacoby,Bang, Dong-Soo,Lee, Jung-Hee,Kim, Taewoo,Kim, Dae-Hyun Elsevier 2018 Solid-state electronics Vol.147 No.-

<P><B>Abstract</B></P> <P>We have fabricated and characterized L<SUB>g</SUB> = 0.5 μm In<SUB>0.52</SUB>Al<SUB>0.48</SUB>As/In<SUB>0.7</SUB>Ga<SUB>0.3</SUB>As pseudomorphic high-electron-mobility-transistors (PHEMTs) on a 3-inch InP substrate. Stepper-based photo-lithography was used in all the process steps for device fabrication, aiming to miniaturize key device geometries, such as gate-to-source and gate-to-drain spacing. The fabricated device with L<SUB>g</SUB> = 0.5 μm exhibits an excellent maximum transconductance (g<SUB>m_max</SUB>) of 1.9 S/mm at V<SUB>DS</SUB> = 1.5 V and an ON-resistance (R<SUB>ON</SUB>) of below 0.4 Ω-mm. A high value of g<SUB>m</SUB> in our device leads to a fantastic combination of current-gain cut-off frequency (f<SUB>T</SUB>) of 120 GHz and maximum oscillation frequency (f<SUB>max</SUB>) of 366 GHz at V<SUB>DS</SUB> = 0.8 V. These remarkable characteristics stem from the compact geometry design of the In<SUB>0.52</SUB>Al<SUB>0.48</SUB>As/In<SUB>0.7</SUB>Ga<SUB>0.3</SUB>As PHEMTs with L<SUB>GS</SUB> = L<SUB>GD</SUB> = 0.4 μm, coupled with an optimized gate recess process that yields tight control of side-recess spacing (L<SUB>side</SUB>). More importantly, the product of f<SUB>T</SUB> and L<SUB>g</SUB> in this work yields 60 GHz-μm which is the highest in any field-effect-transistor (FET) technology on any material system.</P>

Powerelectonics for Pulsed Power Technology in KERI

Geun-hie Rim,E.P. Pavlov,Hong-Sik Lee,Jong-Soo Kim,Youn-Sik Jin,Ju-Won Baek,S.V. Shenderey,Dong-Wook Yoo,G.I. Gusev,S.A. Nikiforov,Young-Hoon Jung,In-Wha Jeong,Young-Wook Choi,Jong-Hyun Kim 전력전자학회 2004 ICPE(ISPE)논문집 Vol.- No.-

This paper reviews the R&D results achieved in Korea<br/> Electrotechnology Research Institute (KERI) in a decade or so. KERI has developed pulsed power technology and its applications mostly based on power electronics. KERI’s R&D activity covers components, military systems, and industry applications.<br/> <br/> High voltage switching means developed in KERI are a rotary arc gap switch (11kV, 400kAp), a vacuum rotary arc gap (20kV, 150kAp), an inverse pinch switch (20kV, 150kAp), and 10kV semiconductor switch stacks made of thyristors and IGBTs. The IGBT and thyristor stacks consists of from ten to twelve 1.2kV discrete devices and<br/> are operated by only one active circuit located in the ground side. Some ferromagnetic opening switch schemes are also researched on trial bases. <br/> <br/> KERI has developed several pulsed power supplies responding to industry needs, of which applications are electrostatic precipitators, high voltage capacitor chargers, polluted gas treatment systems. The investigated pulsed power applications are rock fragmentation system, plasma ion implantation (PSII), food process, and fine metal powder fabrication system using wire-exploding process.