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지제근(Je Geun Chi),서정기(Jeong Kee Seo),황세희(Se Hee Hwang),박경희(Kyung Hee Park),신희영(Hee Young Shin),차한(Hann Tchah) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.4
Arteriohepatic dysplasia is a disorder that is characterized by paucity of interlobular bile duct, neonatal hepatitis-like obstructve jaundice, characteristic facial profile, cardiovascular abnormalities and vertebral arch defect. We experienced 4 cases of Arteriohepatic dysplsia of a 1 year-old male, a 6 month-old female, a 3 year-old female and a 2 year 4 month-old male. L hey all showed persistent cholestasis and character- istic facies. The pulmonary artery stenosis was detected in three of them; vertebral arch defect, in one. The etiologic examnation of the liver showed pauctiy of interlobular bile ducts in all the cases.
뇌척수액내 종양세포의 원발부위 분석 및 세포학적 특징 - 총 1,438예 분석 -
김연미,전미영,지제근,Kim, Yeon-Mee,Jeon, Mi-Yeong,Chi, Je-Geun 대한세포병리학회 2000 대한세포병리학회지 Vol.11 No.2
Cytologlc evaluation of cerebrospinal fluid(CSF) is an effective mean for diagnosing many disorders involving the central nervous systems(CNS). One of the most important reasons for cytologic examination of CSF is to detect metastatic or primary neoplasms of the CNS. We did a retrospective study of 1,438 CSF specimens obtained between 1992 and 1996. A total of 1,205 adult and 233 pediatric CSF specimens from 947 patients were accessed at the Department of Pathology of Seoul National University Hospital and Children's Hospital, respectively. Among 1,438 CSF cytology specimens, 169 cases(11.8%, 77 patients) including 135 adult cases(59 patients) and 34 pediatric cases(18 patients) were positive for malignant cells. Diagnoses included 50 metastatic carcinomas(adult, 60; pediatric, 0); 46 malignant lymphomas(adult, 44; pediatric, 2); 21 leukemias(adult, 20; pediatric, 1); 4 retinoblastomas(adult, 0; pediatric 4); 2 rhabdomyosarcomas(adult, 0; pediatric, 2); 1 multiple myeloma(adult, 1; pediatric, 0), and 35 primary CNS neoplasms(adult, 10; pediatric, 25). The most commonly identified metastatic carcinomas in adults were adenocarcinoma. Their primary sites were the lung, gastrointestinal tract, and breast in order of frequency. The most common primary CNS neoplasm in children was medulloblastoma.
Tannic acid를 이용한 전자현미경 (TEM) 염색효과
윤철종,한정연,김철우,지제근,Yoon, Chul-Jong,Han, Joung-Yeon,Kim, Chul-Woo,Chi, Je-Geun 한국현미경학회 1994 Applied microscopy Vol.24 No.2
Using mouse tissue, we studied electron opacity effect of tannic acid for transmission electron microscopic staining. Tannic acid-glutaraldehyde in 0.1M phosphate buffer was used as a fixative. To compare with this we have tested another method consisting of heavy metal staining after treatment of tannic acid in sodium tetraborate (borax) on glutaraldehyde-fixed sections. We have achieved equally consistent electron opacity in both methods. The elastin, collagen, basal lamina of skin and gap junctions of the epithelial cells gave excellent results, while it was good for glycogen, cilia, and plasma. Also fat cells and lipid droplets gave good preservation when tannic acid was added in the fixative. However, prolonged fixation in tannic acid-added fixative was hazardous for further processing, i.e., sectioning problem and deep electron opacity background.