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Energy Efficient Routing Algorithms : A Survey
Jaspreet Kaur,R C Gangwa 보안공학연구지원센터 2016 International Journal of Future Generation Communi Vol.9 No.1
Energy and bandwidth of the sensors in wireless sensor networks are highly valuable resources so must be used efficiently. Data aggregation on base station via entity nodes is the starting point of overflow of the information, which effect utmost power utilization. To reduce such obstacle, new data aggregation technique has been proposed called ERA which has improved the act of the wireless sensor network through the use of group-based data aggregation but still a lot improvement can be made. This term paper presents a review on various energy algorithms within clustering. And it has been found that none of the technique performs effectively in all fields. The major task of this survey is to find out the drawbacks in existing techniques and ERA. So this paper makes conclusion along with the future scope to overcome these problems.
Clinical Audit in Radiation Oncology: Results from One Academic Centre in Delhi, India
Kaur, Jaspreet,Mohanti, Bidhu Kalyan,Muzumder, Sandeep Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.5
The objective was to analyze the radiotherapy (RT) practice at the cancer centre of a tertiary academic medical institution in Delhi. This audit from an Indian public institution covered patient care processes related to cancer diagnosis, integration of RT with other anti-cancer modalities, waiting time, overall treatment time, and compliance with RT. Over a period of one year, all consecutively registered patients in radiotherapy were analyzed for the audit cycle. Analysis of 1,030 patients showed median age of 49.6 years, with presentation as stage I and II in 14.2%, stage III and IV in 71.2% and unknown stage in 14.6%. A total of 974 (95%) were advised for RT appointment; 669 (68.6%) for curative intent and 31.4% for palliation. Mean times for diagnostic workup and from registration at cancer centre to radiotherapy referral were 33 and 31 days respectively. Median waiting time to start of RT course was 41 days. Overall RT compliance was 75% and overall duration for a curative RT course ranged from 50 days to 61 days. Non-completion and interruption of RT course were observed in 12% and 13% respectively. Radiotherapy machine burden in a public cancer hospital in India increases the waiting time and 25% of advised patients do not comply with the prescribed treatment. Infrastructure, machine and manpower constraints lead to more patients being treated on cobalt (74%) and by two-dimensional (78%) techniques.
Kaur, Jaspreet,Goyal, Shikha,Muzumder, Sandeep,Bhasker, Suman,Mohanti, Bidhu Kalyan,Rath, Goura Kishore Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.19
Aims: To determine the clinical characteristics, pathological features, local and distant failure patterns in patients with carcinoma of major salivary glands treated with surgery and postoperative radiotherapy (PORT). Materials and Methods: We retrospectively reviewed 106 cases of major salivary gland tumor seen at our centre (1998-2008). Sixty five cases of major salivary gland carcinoma were selected for analysis (exclusions: benign, palliative, non-carcinomas). The patient population treated by surgery and PORT was divided into two groups: 1) Patients who underwent surgery and immediate PORT (Primary PORT); 2) Patients with recurrent carcinoma who underwent at least two surgeries and received PORT in the immediate post-operative period of the last performed surgery (Recurrent PORT). Recurrence free survival (RFS) was assessed using the Kaplan-Meier method. Results: Median age was 35 years with a male: female ratio of 1.3:1. The majority of cancers were located in the parotid gland (86.2%) and the most common histology was mucoepidermoid carcinoma (43%). Thirty nine cases (60%) were primary while 26 (40%) were recurrent. Optimal surgery was performed in 59/65 patients (90.8%). 43 patients (66.2%) underwent neck dissection, of which 14 (32.5%) had nodal metastasis. Overall, 61 (93.8%) patients complied with the prescribed radiotherapy. Median dose of PORT was 60 Gy. Median follow-up was 13.1 months (range 2-70). Relapse free survival was 50.4% at 60 months. Some 12 cases (18.5%) recurred with a median time to recurrence of 16.9 months. Conclusions: Surgery and PORT is an effective treatment for major salivary gland carcinoma with over 90% compliance and <20% recurrence. Early treatment with postoperative radiotherapy may increase the survival rate in major salivary gland carcinoma patients.
Long non-coding RNA: its evolutionary relics and biological implications in mammals: a review
( Jasdeep Kaur Dhanoa ),( Ram Saran Sethi ),( Ramneek Verma ),( Jaspreet Singh Arora ),( Chandra Sekhar Mukhopadhyay ) 한국축산학회(구 한국동물자원과학회) 2018 한국축산학회지 Vol.60 No.10
The central dogma of gene expression propounds that DNA is transcribed to mRNA and finally gets translated into protein. Only 2-3% of the genomic DNA is transcribed to protein-coding mRNA. Interestingly, only a further minuscule part of genomic DNA encodes for long non-coding RNAs (lncRNAs) which are characteristically more than 200 nucleotides long and can be transcribed from both protein-coding (e.g. H19 and TUG1) as well as noncoding DNA by RNA polymerase II. The lncRNAs do not have open reading frames (with some exceptions), 3`- untranslated regions (3’-UTRs) and necessarily these RNAs lack any translation-termination regions, however, these can be spliced, capped and polyadenylated as mRNA molecules. The flexibility of lncRNAs confers them specific 3Dconformations that eventually enable the lncRNAs to interact with proteins, DNA or other RNA molecules via base pairing or by forming networks. The lncRNAs play a major role in gene regulation, cell differentiation, cancer cell invasion and metastasis and chromatin remodeling. Deregulation of lncRNA is also responsible for numerous diseases in mammals. Various studies have revealed their significance as biomarkers for prognosis and diagnosis of cancer. The aim of this review is to overview the salient features, evolution, biogenesis and biological importance of these molecules in the mammalian system.
Living Experiences of Indian Adult Cancer Survivors - a Brief Report
Mohanti, Bidhu Kalyan,Kaur, Jaspreet Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.2
Background: This pilot study looked into the physical, social, psychological and economic issues of Indian adult cancer survivors. Materials and Methods: Assumed cancer free patients, after cancer directed therapy (CDT), were assessed on the basis of a questionnaire developed by the investigators. The mental status of the survivors was elicited by modified MINI international neuro-psychiatric interview. This cross sectional assessment was conducted as a direct interaction with each patient for 30 to 45 minutes at a cancer hospital in 2012. Results: Thirty one adult cancer survivors participated in this study. Median age was 53 years with a median follow up duration of 21.8 months (Range 2.3-194.1 months). The majority (68%) did not receive financial support for treatment. Median interval after CDT to start of activity of daily living was 1.5 months (range: 0-24 months). Fatigue and loss of appetite were reported by 52% and 29% respectively. The cancer diagnosis and its treatment adversely impacted the financial condition in 42% of patients. Nineteen percent each showed social anxiety and post-traumatic stress disorder and another 13% patients reported depression. Conclusions: This prospective assessment highlights survivorship issues and the need to address those issues particularly in the context of developing countries where resources and manpower are limited.
Harminder Singh,Anu Sheetal,Jaspreet Kaur,Maninder Singh,Manupriya Sharma 대한금속·재료학회 2023 ELECTRONIC MATERIALS LETTERS Vol.19 No.5
The main idea behind this study is to fabricate a cost-effective and eco-friendly source of electrical energy for battery-less IOT devices, sensors and small medical/electronic wearable devices, as per the UN’s sustainable development goal SDG 7 (affordable and clean energy). In this study, an electrical energy generation device triboelectric nanogenerator (TENG) is designed and fabricated from fish fin, which is biocompatible, non-toxic, and treated as waste material in the fish market. The fish fin isolated from the waste of the fish is converted to the dielectric layer of the TENG, which is further utilized to convert ambient mechanical energy into useful electrical energy. The thermal stability of the material also has been tested using TGA, and it was observed that it was stable to work up to 100°C. Other biomaterial combinations of egg shell membrane, dog hairs, and tree cotton are also tested in this study. The output of the fish fin based fabricated TENG is utilized to power up 65 green LEDs connected in the series, which is equivalent to 130 V of voltage, and the current of 1.1µA was measured across a 1MΩ resistor. This output of the TENG was used to power up a small digital watch. The fabricated device can also be used as sensor to detect human motion.
Biocomputational Characterization and Evolutionary Analysis of Bubaline Dicer1 Enzyme
Singh, Jasdeep,Mukhopadhyay, Chandra Sekhar,Arora, Jaspreet Singh,Kaur, Simarjeet Asian Australasian Association of Animal Productio 2015 Animal Bioscience Vol.28 No.6
Dicer, an ribonuclease type III type endonuclease, is the key enzyme involved in biogenesis of microRNAs (miRNAs) and small interfering RNAs (siRNAs), and thus plays a critical role in RNA interference through post transcriptional regulation of gene expression. This enzyme has not been well studied in the Indian water buffalo, an important species known for disease resistance and high milk production. In this study, the primary coding sequence (5,778 bp) of bubaline dicer (GenBank: AB969677.1) was determined and the bubaline Dicer1 biocomputationally characterized to determine the phylogenetic signature among higher eukaryotes. The evolutionary tree revealed that all the transcript variants of Dicer1 belonging to a specific species were within the same node and the sequences belonging to primates, rodents and lagomorphs, avians and reptiles formed independent clusters. The bubaline dicer1 is closely related to that of cattle and other ruminants and significantly divergent from dicer of lower species such as tapeworm, sea urchin and fruit fly. Evolutionary divergence analysis conducted using MEGA6 software indicated that dicer has undergone purifying selection over the time. Seventeen divergent sequences, representing each of the families/taxa were selected to study the specific regions of positive vis-$\grave{a}$-vis negative selection using different models like single likelihood ancestor counting, fixed effects likelihood, and random effects likelihood of Datamonkey server. Comparative analysis of the domain structure revealed that Dicer1 is conserved across mammalian species while variation both in terms of length of Dicer enzyme and presence or absence of domain is evident in the lower organisms.
Himanshi Mehta,Megha Gupta,Parminder Kaur,Jaspreet Kaur,Naveen Kaushal 한국진공학회(ASCT) 2021 Applied Science and Convergence Technology Vol.30 No.3
Biomolecules mediated synthesis of nanoparticles (NPs) has revolutionized the nanotechnology research field due to its eco-friendly and non-toxic nature. The green approaches of NPs synthesis using plant extracts offer an effective and better alternative than other synthesis methods. Metal-based NPs have emerged at the forefront of biomedicine due to their versatility in health and therapeutics. In this context, Selenium (Se), a versatile trace element is known for its critical role in various pathophysiological processes through regulation of cellular redox status and inflammatory pathways besides others. However, these beneficial effects of Se are limited by its narrow physiologically relevant concentration range. Deficiency or excess of Se is associated with numerous pathologies and toxicities. Thus, in current study we have synthesized and characterized Hempseed (Cannabis sativa) based novel biogenic Se nanoparticles (SeNPs) using UV visible spectroscopy, DLS, EDX, FE-SEM, and FT-IR. Further, the phytochemical profiles and antioxidant as well as anti-inflammatory potential of these SeNPs were evaluated to ascertain their physiological benefits. Results indicated the spherical shaped SeNPs of average size 140–150 nm with favourable zeta potential of −45.0 mV. The phytochemical and Se analysis validated the redox modulatory anti-inflammatory potential of these hempseed based green SeNPs.
Biocomputational Characterization and Evolutionary Analysis of Bubaline Dicer1 Enzyme
Jasdeep Singh,Changdra Sekhar Mukhopadhyay,Jaspreet Singh Arora,Simarjeet Kaur 아세아·태평양축산학회 2015 Animal Bioscience Vol.28 No.6
Dicer, an ribonuclease type III type endonuclease, is the key enzyme involved in biogenesis of microRNAs (miRNAs) and small interfering RNAs (siRNAs), and thus plays a critical role in RNA interference through post transcriptional regulation of gene expression. This enzyme has not been well studied in the Indian water buffalo, an important species known for disease resistance and high milk production. In this study, the primary coding sequence (5,778 bp) of bubaline dicer (GenBank: AB969677.1) was determined and the bubaline Dicer1 biocomputationally characterized to determine the phylogenetic signature among higher eukaryotes. The evolutionary tree revealed that all the transcript variants of Dicer1 belonging to a specific species were within the same node and the sequences belonging to primates, rodents and lagomorphs, avians and reptiles formed independent clusters. The bubaline dicer1 is closely related to that of cattle and other ruminants and significantly divergent from dicer of lower species such as tapeworm, sea urchin and fruit fly. Evolutionary divergence analysis conducted using MEGA6 software indicated that dicer has undergone purifying selection over the time. Seventeen divergent sequences, representing each of the families/taxa were selected to study the specific regions of positive vis-à-vis negative selection using different models like single likelihood ancestor counting, fixed effects likelihood, and random effects likelihood of Datamonkey server. Comparative analysis of the domain structure revealed that Dicer1 is conserved across mammalian species while variation both in terms of length of Dicer enzyme and presence or absence of domain is evident in the lower organisms.
Patterns of Cancer: A Study of 500 Punjabi Patients
Bal, Manjit Singh,Bodal, Vijay Kumar,Kaur, Jaspreet,Kaur, Mohanvir,Sharma, Swati Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.12
The State of Punjab has been in focus because of aperceived increasing rate of cancer. Both print and electronic media have created an impression that Punjab, especially the cotton belt of Malwa Region, has become a high incidence cancer region. Actually the increased number of cancer patients might be at least partly because of increasing population and heightened health awareness and reporting. The purpose of this study is to find out the pattern of cancer amongst patients registered in Mukh Mantri Punjab Cancer Rahat Kosh Scheme (MMPCRKS), under cancer registry at Rajindra Hospital Patiala from the various districts of Punjab. The study covers 500 cancer patients registered under MMPCRKS at Rajindra Hospital Patiala, for free cancer treatment. Information regarding age, gender, religion, method of diagnosis and affected sites was obtained. Results were analyzed statistically. Of the 500 patients, 65% were females and 35% were males. The most affected female age groups were 50-54 and 60-64; while males in the age groups of 65-69 and 60-64 had the highest risk. The leading cancers in females were breast followed by cervix and ovary where as in males they were were colon followed by esophagus and tongue. The commonest histological type was adenocarcinoma followed by squamous cell carcinoma. The increasing trend of cancer in Punjab is alarming. Since this study is a preliminary investigation, it could provide a leading role in prevention, treatment and future planning regarding cancer in Punjab.