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An Jae Seong,Kim Do Hyun,Kim Soo Whan,Kim Sung Won,Lee Il Hwan 대한비과학회 2023 Journal of rhinology Vol.30 No.1
Background and Objectives: We compared pain levels, cardiovascular parameters, and complications according to whether patients underwent nasal packing with non-absorbable or biodegradable materials. Methods: Patients who underwent septoplasty from May 2015 to April 2020 were retrospectively reviewed. Numeric rating scale (NRS) scores for pain, blood pressure, and heart rate were measured three times (immediately after surgery, 6 hours later, and on postoperative day [POD] 1). We collected data on complications, including postoperative bleeding, septal hematoma, adhesions, septal perforation, and the recurrence of septal deviation. Results: In total, 200 patients underwent septoplasty, of whom 100 underwent nasal packing with Merocel and 100 underwent packing with Nasopore. The summed NRS scores over the three time points did not differ significantly between the groups. The NRS scores at 6 hours after surgery were highest in both groups. The systolic and diastolic blood pressure and the heart rate immediately after surgery were significantly higher than before surgery in both groups. The blood pressure and heart rate at 6 hours after surgery and on POD 1 did not differ significantly from those before surgery in either group. The incidence of sleep disturbance, postoperative bleeding, septal hematoma, adhesions, septal perforation, and recurrence of septal deviation did not differ significantly between the two groups. Conclusion: Although the level of postoperative pain and the cardiovascular parameters changed over time, we found no significant differences in pain, blood pressure, heart rate, or the complication rate according to whether patients underwent nasal packing with Nasopore or Merocel.
An Jae Seong,Kim Do Hyun 대한비과학회 2023 Journal of rhinology Vol.30 No.2
An inverted papilloma of the frontal sinus is a challenging lesion for surgeons, for both anatomical and pathological reasons. Despite the trend away from an external approach and towards an endonasal endoscopic approach, indications for an external approach remain. The options for an external approach include endoscopic frontal trephination, transpalpebral orbital craniotomy, a supraorbital transeyebrow approach, an osteoplastic flap, and bifrontal craniotomy with cranialization. Each approach has advantages and disadvantages. Deciding on the appropriate approach is important for the patient’s prognosis and risk of complications. We report two cases of frontal sinus inverted papilloma treated with a combined bifrontal craniotomy with cranialization and endonasal endoscopic approach. We also present a general review of the external approaches mentioned above.
Analysis of Air Flow inside the Compartment under Backdraft Conditions using Solid Combustibles
Jaeseong An(Jaeseong An),Taehoon Kim(Taehoon Kim) 한국화재소방학회 2022 International Journal of Fire Science and Engineer Vol.36 No.2
Backdraft is a phenomenon of explosive combustion that occurs when fire in a state of smoldering due to the lack of oxygen grows as the air is admitted after opening the entrance door or window. In this study, a reduced compartment was produced to simulate a backdraft. In an actual site, the fire was generated by solid combustibles, and hence, wood pieces were used to generate the backdraft in this study. Twenty-seven thermocouples were installed inside the compartment. One side of a wall consists of polycarbonate and the interior of the compartment was monitored using a camera. An additional fire simulation was performed using a fire dynamics simulator for in-depth analysis of the phenomena inside the compartment. In the experiment, the air flown into the compartment through the vent opening turned the smoldering fire of solid combustibles into the flaming fire, which led to the ignition of flammable gas inside the compartment. Next, the propagation of the flame was first directed upwards to the combustibles, then towards the center, and ultimately to the exterior. This phenomenon was observed in the analysis of the compartment holding a homogeneous flammable mixture. The results of the analysis showed that the flammable mixture on the interior was released to the exterior because of the rise in the internal pressure caused by flame propagation. Consequently, as the internal flame was propagated to the exterior, the mixture was ignited. Thus, the phenomenon of backdraft in the case of compartment fire was shown to occur as follows. First, the air flown in via the vent opening was elevated to the upper part of the compartment by the smoldering heat on the interior. Next, the flame led to the ignition of the flammable mixture formed on the upper part.
재난재해에 대응 가능한 보급형 실내 임시주거시설의 계획에 관한 연구
Jaeseong Ju,Mijin Park 한국재난정보학회 2017 한국재난정보학회 논문집 Vol.13 No.4
국내에서도 홍수, 지진, 산사태, 화재 등의 다양한 재난재해로 인하여 이재민이 발생하고 있으며, 이 중 대다수가 이재민 임시주거시설로 대피하고 있다. 그러나 이재민 임시주거시 설 내에서 개인공간을 확보할 수 있는 실내 임시주거시설의 배치와 성능에 관한 계획은 미 비하다. 이에 이재민 임시주거시설 내 거주환경을 개선하기 위하여, 국민안전처에서 지정 한 1인당 최소 수용면적 3.3㎡로 실내 임시주거시설의 모듈을 구축, 모듈의 배치계획을 진 행하였으며, 실내 임시주거시설의 형태, 재료, 성능에 대한 평가 방향을 제시하였다. Even in South Korea, disaster victims are suffering from various disasters such as floods, earthquakes, landslides, fires, and most of them have evacuated to temporary housing facilities for disaster victims. However, there are few plans for the placement and performance of indoor temporary housing facilities provided to secure private space in temporary housing facilities for disaster victims. In order to improve the living environment in the temporary housing facility of the victim, we constructed a module of minimum temporary accommodation area per person of 3.3 square meters, designated by the MPSS, and are proceeding with the module arrangement plan, Presented the evaluation direction of the form, material and performance of the indoor temporary housing facility.
Review of toxicity prediction studies using toxicity database
Jaeseong Jeong(정재성),Jinhee Choi(최진희) 환경독성보건학회 2021 한국독성학회 심포지움 및 학술발표회 Vol.2021 No.5
Recently, computational toxicology has emerged that predicts toxicity without conducting toxicity tests at all. This has become possible due to the rapid development of computer technology, and various computational toxicology techniques such as quantitative structure-activity relationship (QSAR) that predict toxicity based on the structure of chemical substances are attracting attention. Currently, research are underway to apply artificial intelligence techniques used to process big data in various fields to toxicology, mainly in scientifically advanced countries. The competition for the development of toxicity prediction models using artificial intelligence is accelerating, and techniques are becoming increasingly complex. To develop a toxicity prediction model using artificial intelligence and use it for regulation, it is necessary to understand the recent development. In this study, we analyze toxicity prediction studies using artificial intelligence techniques, and summarize artificial intelligence algorithms and prediction performance used in recent papers. We have analyzed over 70 papers published since 2014. Models have been developed to predict about 30 different toxicity endpoints using more than 20 toxicity databases. In the development of the model, MACCS fingerprint and random forest algorithms were used the most. The use of artificial intelligence techniques in the development of toxicity prediction models is a fairly new challenge, requiring active and diverse efforts toward a scientific accord and regulatory application. The comprehensive overview provided in this study could be used as a useful guide to further development and application of toxicity prediction models.