유방암의 뇌하수체 전이에 의한 양안 시력소실 1 예

최낙원,안명주,김재민,박동우,박용욱 한양대학교 의과대학 2000 한양의대 학술지 Vol.20 No.1

Pituitary gland metastasis is a rare clinical diagnosis, usually made in the setting of known primary systemic cancer with widespread metastasis to other organs. But visual loss as a presenting symptom of metastasis to the pituitary gland is unusal. We report here a case of 45-year-old woman who had been diagnosed as having metastatic breast cancer involving bone and liver 2 years ago, and received high dose chemotherapy with peripheral blood stem cell transplantation, developed sudden bilateral complete visual loss. At initial presentation, the patient had no light perception and no pupillary response to light in both eyes, but without evidence of panhypopituitarism, or diabetes insipidus. Brain MRI showed a large enhanced mass invasion to the cavernous sinus and extension to the suprasella portion without dura or base-of-skull metastasis. Pathologic examination showed metastatic breast cancer. Despite the transsphenoidal decompression surgery of metastatic tumor, the visual loss was not improved.

입상활성탄의 자연발화 특성에 관한 연구

최재욱,김상렬 東亞大學校 大學院 1993 大學院論文集 Vol.18 No.-

The characteristics of critical spontaneous ignition of granulated activated carbon were investigated at a constant ambient temperature and sinusoidally varying ambient temperatures. As the results of the experiments, the critical spontaneous ignition temperature at the sinusoidally varying ambient tem-peratures was generally lower than that at the constant ambient temperature. At the critical spontaneous ignition temperature decreased as the period increased. The critical Frank-Kameneskii's parameter δ?(εω) was determinded from the results. δ?(εω) = δ?{1-379 exp (-0.935·ω?)} δ?(εω) = δ?{1-381 exp (-0.930·ω?)} δ?(εω) = δ?{1-388 exp (-0.929·ω?)}

입상활성탄의 입도 크기에 따른 자연발화 특성에 관한 연구

최재욱,김상열 동아대학교 공과대학 부설 한국자원개발연구소 1993 硏究報告 Vol.17 No.2

The spontaneous ignition characteristics according to particle size of granulated activated carbon were observed at a constant ambient temperature. As the results of the experiments at the same sample size, the ignition induction time increased as the sample vessel size increased and the critical spontaneous ignition temperature decreased as the sample vessel size increased. As the sample particle size increased, the critical spontaneous ignition temperature decreased. Apparent activation energy of the sample calculated from the Frank-Kamentskii's thermal ignition theory was 37.73 ㎉/㏖.

축전지 사업장에서 공기 중 납 농도의 허용노출기준 초과율 변화에 관한 연구

최재욱,김남수,함정오,이병국 순천향대학교 의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.2

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일부 산업재해 환자들에서 외상후 스트레스장애

최경숙,임채기,최재욱,강성규,염용태 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.3

연구목적 : 우리나라에서 산업 재해로 신체적 손상을 입고 입원해 있는 일부 근로자들을 대상으로 PTSD 발병여부를 조사하고, 산업 재해와 관련된 위험 인자를 파악하여 산업재해 이후 근로자들이 겪게 될 신체적 건강문제 뿐만 아니라 정신적 건장 문제 회복에 도움을 주고자 하였다. 방 법 : 2000년 7월에서 2000년 9월 사이에 산업 재해로 인해 신체적인 부상을 입고 입원 중인 인천 소재 산재병원의 남성 입원환자 47명을 대상으로 PTSD 발병여부와 관련 인자를 연구하기 위하여 구조화된 설문 조사와 CAPS를 이용한 진단적 면담을 시행하였다. 결 과 : CAPS를 이용한 면접조사 결과 최종 연구 대상자 47명중 12명(25.5%)이 PTSD로 나타났으며, 모두 증상의 지속 기간이 3개월 이상인 만성 외상후 스트레스장애로 분류되었다. PTSD군 12명과 non-PTSD군 45명을 비교한 결과 BDI, STAI-I, STAI-II, IES 점수는 PTSD 군에서 유의하게 높게 나타났다. 또한 SCR-90-R의 세부항목 중 편집 사고를 나타내는 PAR 점수가 유일하게 두 군 사이에 유의한 차이를 보이지 않았고 그 외의 항목들은 PTSD 군에서 유의하게 높았다. 산재 관련 위험 인자의 비교에서 환자가 주관적으로 보고한 의식의 상실 경험만이 PTSD군에서 유의하게 높게 나타나 이전의 다른 연구자와 일치된 소견을 보였다. 결 론 : 이상의 결과는 산재 사고 이후에 PTSD가 발생하고, 증상이 장기간 지속되어 만성화를 겪을 가능성이 있다는 것을 보여준다. 위험 인자 중에서 사고 관련 위험 인자로 의식의 상실에 대한 주관적인 보고만이 관련성이 있는 것으로 나타났으나, 그 외의 다른 인자들은 관련서이 없는 것으로 나타났다. 그러나 여러 가지 연구의 제한점이 많으므로 연구 시점을 달리하고 많은 대상자를 포함한 후속 연구를 시행해야 산업재해와 PTSD에 대한 이해를 높일 수 있을 것으로 사료된다. Objectives : This study was conducted to assess the development of posttraumatic stress disorder(PTSD) after occupational physical injuries and the risk factors in occupational accident patients for PTSD. Methods : Forty-seven occupational accident patients with physical injuries were administered BDI. STAI I and II, SCL-90-R, IES and questionnaires for risk factors and Clinician-Administered PTSD Scale(CAPS). Results : 1) 12 patients(25%) were diagnosed as PTSD. 2) The BDI, STAI I and II and IES scores are significantly high(<0.05) in PTSD group than non-PTSD group. 3) The subscales of SCL-90-R, with an exception of PAR subscale, showed higher scores(<0.05) in PTSD group. 4) The loss of consciousness(LOC) was only significant risk factor in the occupational accident related factors(<0.05). Conclusion : The results of this study show the development of PTSD among occupational accident patients. The loss of consciousness(LOC) was the only significant risk factor for PTSD in occupational accident patients.

특발성 좌심실빈맥(Idiopathic Left Ventricular Tachycardia)의 성공적인 전극도자절제술을 위해 단극전기도(Unipolar Electrogram)가 유용한가?

최기준,남기병,강덕현,홍명기,송재관,김재중,박성욱,박승정,박종훈,김유호 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.4

한국 일부지역의 이주근로자의 근로조건과 산업재해실태 조사

최재욱,김정아,김해준,박종태 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.1

This study was conducted to evaluate and to recognize the status and the problems of working conditions, and industrial accidents for migrant workers in a group of 342 who lives in Ansan area, Kyunggi province. By the questionnaire written by 5 languages(English, Bangladesh, Indonesian, Chinese and Korean), the informations of socio-demographic factors, occupational conditions of engaged company and general & occupational health status were obtained from June, 1st to July 30th, 1998. We used the ANOVA to examine differences of working hours, days and average monthly wages between overseas industrial trainee and illegal migrant workers, and by using logistic regression, odds ratio of general risk factors for industrial accidents in migrant workers were calculated. The results obtained were as follows: 1. The major distribution of nationals were from Philippine, Indonesia, Bangladesh and China(92.1%), and the most of subjects were man(78.9%) and over high school graduate(81.9%). 2. Most migrant workers worked at small scale companies under 50 employees, and engaged in dye·textile·clothing·leather industry. The average working hours were 59.9 hours per week in overseas industrial trainee, 64.9 hours in illegal migrant worker respectively. 3. Trainees have transferred to another company for 1.89 times, and workers who have changed qualification from trainee to illegal status were 3.09 time, and illegal workers moved 2.36 times. The major portion of reason to move to another company were low salary and overdue salary. 4. Trainees, workers who have changed position from trainee to illegal status, and illegal workers knows 62.27%, 42.31%, and 20.45% in each about legal documentation for foreign industrial trainees in Korea "Regulations for protecting and managing of foreign industrial trainees in Korea " published on March 1995. Additionally, trainees and illegal workers have experienced medical examination by 52.3% and 18.2% respectively. 5. Industrial accident condition from Jun. 1st, 1997 to Dec. 31th, 1997 were as follows : in case of frequent rate, trainees and illegal workers were 30.04, 23.78 each, and 8.6%, 7.4% for industrial accident rate respectively. 6. The most common causes and types of industrial accident were inappropriate motions of body and abrasion, and body sites most vulnerable to injury were the hands and fingers. The results suggest that working status and industrial accidents of migrant workers are very poor in Korea. Therefore, occupational safety and health policy aimed at migrant workers are needed to protect the migrant workers.

비중격 천공이 없는 크롬 노출 근로자에서의 후각장해에 관한 연구

최재욱,이성희,최연국,이은일,김해준 대한산업의학회 2000 대한직업환경의학회지 Vol.12 No.2

Objectives : The chrome-induced olfactory alterations is caused by inhalation of chromic acid, a highly corrossive and toxic materials. And nasal septum perforation (NSP) has been suspected with possible causative factor of olfactory alterations. To our knowledge, there has been no report of the detailed findings of the olfactory alterations in chrome exposed subjects without nasal septum perforation (NSP). So we present the results of olfactory function test measured by T&T olfactometer and olfactometer perception test among chromium exposed workers without NSP. Methods : We performed this study in 25 study subjects and 25 control subjects matched with age, alcohol and smoking. All of subjects are man. We performed olfactory function test measured by T&T olfactometer and olfactometer perception test. Results : 1) The age distribution of the subjects involved in this study was from 20 to 54 years old (average 33.3 years old) and the mean duration exposed to chromium was from 64.9 months. 2) The olfactory function was checked by detection and recognition thresholds in five odorants. The detection thresholds of exposed group dealing with chromium were significantly increased in A and B ordorants than nonexposed group. The recognition thresholds of exposed group were significantly increased in D ordorants than nonexposed group. 3) The mean threshold of olfactometer perception test of exposed group were more increased than nonexposed group. But thresholds difference did not show statistical significance. 4) The detection thresholds of A and D ordorants, recognition threshold of C ordorants and thresholds of olfactometer perception test were increased in the relation with duration of chrome exposure. Conclusions : There has been no remarkable alterations in olfactory sense (T&T olfactometer and Olfactometer Perception Test) in subjects without nasal septum perforation (NSP) exposed to chromic acid.

안면부에 발생한 고정형 스포로트리쿰증 3례

최윤애,류영욱,정재봉,송준영,이규석 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.3

We experienced 3 cases of fixed type cutaneous sporotrichosis confined to the face. Case 1 was a 32-month old child, affected over the nose. Case 2 was a 25-year old man, affected over the left cheek. Case 3 was a 71-year old man, affected over the nose. Histopathologically, chronic granulomatous inflammation with pseudoepitheliomatous hyperplasia was observed. Mycologically, typical dark brown to black colored colonines with moist, wrinkled and membranous surfaces were cultured. All patients were completely cured by oral administration of saturated KI and itraconazole combined therapy in a short period(40-90 days).

반복 작업 근로자들에서의 경견완장애에 관한 연구

최재욱,염용태,송동빈,박종태,장성훈,최정애 大韓産業醫學會 1996 대한직업환경의학회지 Vol.8 No.2

본 연구는 근골격계 질환중에서 대표적인 질환인 경견완장애를 대상으로 일부 제조업 및 전화교환수 근로자에서의 경견완장애의 유병실태 파악, 경견완장애의 정확한 분류 및 향후 진단기준의 개발에 필요한 기초적인 자료 수집에 목적을 두었다. 조사대상은 반복동작에 폭로되는 생산직 근로자 98명, 모전화국의 전화교환수 115명을 대상으로 근골격계 증상호소, 이학적 검사 및 신경학적검사와 기타 혈중 효소등의 임상검사 및 악력의 차이 등을 조사하였다. 조사대상 사업장 중 B사업장은 전자부품을 생산하는 사업장으로, 제품 조립라인의 작업형태는 주야 2교대 근무이며, 앉아서 하는 작업과 서서하는 작업이 혼재 되어있다. A사업장은 전화교환작업, 즉 컴퓨터단말기를 취급하는 작업으로 전원 앉아서 하는 작업이며, 주야 2교대 작업이다. 조사대상 집단의 일반적 특성은 다음과 같다. A사업장 근로자의 평균 연령은 37.9세, 평균 근속년수는 17년이며, B사업장은 평균 연령 37.7세, 평균 근속년수 10.4년이었다. A 사업장은 대상 근로자 115명이 전원 여자였으며, B사업장은 대상근로자 98명 중 남자 68(69.4%)명, 여자 30(30.6%)명이었다. 조사 결과는 다음과 같다. 사업장별 자각 증상 호소율은 A 사업장의 경우 경부 85.2%, 견관절 81.7%, 주관절 34.8%, 완관절 73.0%의 순으로 특히 경부 및 견관절, 완관절의 증상 호소율이 높았으며, 반면 B 사업장은 경부 51.2%, 견관절 56.1% 주관절 23.5%, 완관절 31.3%의 순이었다. 근속년수별 자각증상 호소율은 경부와 견관절의 자각증상 호소율이 40%이상으로 주관절 및 완관절의 지각 증상 호소율에 비해서 상대적으로 높았으며, 경부와 완관절은 근속년수가 증가함에 따라 자각증상에 호소율이 통계적으로 유의하게 증가하였다. A 사업장, B 사업장 모두 최소 22.8% 이상의 근로자(증상 경험자중)가 병원이나 약국을 방문하여 치료를 받았다고 응답하였으며, 사업장 간의 차이는 보이지 않았다. 조사 대상자 전원에게 신경학적 검사와 근전도 검사를 포함한 정밀건강진단을 실시하였다. 정밀건강진단 결과 A 사업장은 질병자가 10명(8.6%), 요주의자가 31명(26.9%), 재검자가 2(1.7%)이었으며, B 사업장은 질병자가 16(16.3%), 요주의자가 12명(12.2%), 재검자 2명(2.0%)이었다. 이러한 이상자의 질병별 유형은 긴장성 경부증후군에 해당하는 사람이 46명으로 이 중 질병자는 13명, 요주의자 30명 재검자 3명이었으며, 수근관증후군은 16명으로 질병자 3명, 요주의자 8명, 재검자 5명이었다. 기타 드퀘르뱅씨병은 5명으로 질병자 4명, 요주의자 1명이었으며, 외측상과염 3명, 이두근개건염 3명, 회전근개건염 3명, 내측상과염 2명, 경추디스트증후군이 5명 등이었다. 사업장별로는 A 사업장의 경우 긴장성경부증후군이 11명, 수근관증후군이 8명, 드퀘르뱅씨병 3명, 경추디스크증후군이 1명이었으며, B 사업장은 긴장성경부증후군이 35명, 수근관증후군이 8명, 드퀘르뱅씨병 2명등의 순이었다. 이러한 결과는 A 사업장의 경우 작업 조건이 의자에 앉아서 실시하는 컴퓨터 작업인데 반하여 B 작업장은 대부분 기립작업, 반복 조립으로 이러한 작업조건에 차이에 기인하는 것으로 판단된다. 경견완장애의 이상소견과 관련이 있는 성별, 연령, 빈도 위험도 점수 및 힘 위험도를 독립변수로 설정하여 다단계 로지스틱 회귀분석을 실시하였다. 경견완장애 이상소견에 통계적으로 유의한 영향을 미친 변수는 성별(p=0.0005), 연령(p=0.0093)이었으며, 힘위험도는 p값이 0.0567, 빈도위험도는 0.0983으로 유의하지 않았다. The purpose of this study is to investigate the current status of and to collect the basic informations of musculoskeletal diseases of upper extremities in manufacturing and telecommunication companies. The subjects were 213 workers, consisted of 98 manufacturing workers and 115 telephone operators. The musculoskeletal symptom survey, job safety analysis(JSA), and medical examinations including neurologic and nerve conduction velocity(NCV) test were conducted. All workers were women in company A, while the other composed of 68(69.4%) men and 30(30.6%) women. The results were as follows: 1. The rates of self-reporting symptoms in each company were 85.2% at the neck, 81.7% at the shoulder joint, 73.0% at the wrist joint and 34.8% at the elbow joint in company A, while 56.1% at the shoulder joint, 51.2% at the neck and 23.5% at the elbow joint in company B in order. 2. No relationship was observed between the work duration and symptom rate in company A, but the highest symptom rate was observed at the neck in 10-19 year work duration group, at the shoulder, elbow and wrist joint in 5-9 year work duration group in company B. 3. Over the 22.8% of total workers in this study having symptoms got medical treatment at the medical clinics or drug stores, but there was no statistical difference between both companies. 4. In company A, 16(13.9%) workers were classified as D category, 12(10.4%) workers as C category and 2(1.7%) workers as R category among 115 workers. And D category was 10(10.2%), C category 31(31.6%) and R category 4(4.0%) among 98 workers in company B. D category means disease category needed futher treatment, C category means disease category needed no treatment and R category means recheck category needed futher evaluation. 5. The types of musculoskeletal disorders including D, C, and R category were 46 cases(D 13, C 30, R 3)of tension neck syndrome (TNS), 16 cases(D 3, C 8, R 5) of carpal tunnel syndrome (CTS), 5 cases of De Quervain's disease, 3 cases of lateral epicondylitis, 3 cases of bicipital tendinitis, 3 cases of rotator cuff tendinitis, 2 cases of medical epicondylitis, and 5 cases of cervical disc syndrome. 6. In company A, the total cases of 11 TNS, 8 CTS, 3 De Quervain's disease, 3 lateral epicondylitis, 3 rotator cuff tendinitis and 1 cervical disc syndrome were diagnosed and so were total cases of 35 TNS, 8 CTS and 4 cervical disc syndrome in company B. 7. By stepwise multiple regression analysis with dichotomization of musculoskeletal disease, the following odds ratios were significantly high(p<0.05)-sex(2.707) and age (1.926).