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김재홍,윤기범,박평원,김영진,전경민,김영태,김중환,곽호,구상완,송민석,유옥,지혜구,김동원,문상은,박영립,정승호,성범진,성순제,엄주용,황정열,이기홍,이주협,전태진 대한화학요법학회 1994 대한화학요법학회지 Vol.12 No.1
The prevalence of PPNG among pretreated gonorrhea cases isolated at the STD clinic of Choong-Ku Public Health Center in Seoul has been studied and reported annually since 1981. In 1991, 123 strains of N.gonorrhoeae were isolated, among which 58(47.1%) were PPNG. In 1992, 98 starains of N.gonorrhoeae were isolated, among which 51(52.0%) were PPNG. In all, 109(49.3%) strains were found to be PPNG among 221 strains isolated between 1991-1992. The prevalence of PPNG in Seoul showed increased tendency till 1989, thereafter, it has been stationary or slightly decreasing.
이석종,전재복,김도원,정상립 慶北大學校 醫科大學 1994 慶北醫大誌 Vol.35 No.4
목적 : Pityrosporum ovale는 지루피부염의 발생에 중요한 역할을 하며 이 친지성 진균은ketoconazole제재에 감수성이 있다고 알려져 있다. 이에 저자들은 두피에 사용하기 편리한 2% ketoconazole 샴푸로 지루피부염을 치료하여 그 효과를 확인하고자 본 조사를 실시하였다. 대상 및 방법 : 두피의 지루피부염 환자 52명에게 소양감의 정도를 설문조사하고 피부과 의사의 육안으로 인설의 양을 검사한 후 광학현미경 고배율하에서 진균학적 검사를 실시하였다. 결과 : 지루피부염 환자의 소양감과 인설의 양은 치료전에 비해 치료 2주와 4주 모두에서 유의하게 감소하였으며(p<0.05) 이들 환자에서 실시한 Pityrosporum ovale의 평균 포자수 역시 치료전에 비해 치료 2주와 4주 모두에서 유의하게 감소하였다(p<0.05). 결론 : ketoconazole 샴푸는 지루피부염의 임상 및 진균학적인 면 모두에서 치료효과가 있는 것으로 판단되며 간접적으로나마 Pityrosporum ovale가 지루피부염의 발생에 관여한다는 사실을 알 수 있었다. It is suggested that Pityrosporum ovale may play an important role in the pathogenesis of seborrheic dermatitis and this organism is sensitive to ketoconazole compound. So the efficacy of 2% ketoconazole shampoo in the treatment of seborrheic dermatitis was tested and was calculated by mean scores of scale, itching and yeast cells. We interviewed fifty two patients with seborrheic dermatitis about the degree of itching and examined with naked eyes the scale of scalp of them. In a group of the patients, mycological study of P. ovale was also performed by direct smear with 20% KOH solution containng 1 : 1 Parker-ink^R The results were as follows : As for itching and scale of the scalp, the scores were significantly decreased at week 2 and week 4 as the duration of treatment prolonged in comparison with that of week 0. The mean yeast cell score at the two points of time was also significantly decreased in comparison with that of week 0. There was no significant difference in the response from the view of age, sex and duration of seborrheic dermatitis. It is suggested that the shampooing with ketoconazole 2% shampoo every three other days gave a good result clinically and mycologically.
Kim, Tae-Hoon,Yang, Pil-Sung,Kim, Daehoon,Yu, Hee Tae,Uhm, Jae-Sun,Kim, Jong-Youn,Pak, Hui-Nam,Lee, Moon-Hyoung,Joung, Boyoung,Lip, Gregory Y.H. American Heart Association 2017 Stroke Vol. No.
<P>Conclusions-The CHA(2)DS(2)-VASc score shows good performance in defining truly low-risk Asian patients with atrial fibrillation for stroke compared with CHADS(2) and ATRIA scores.</P>
Ideal Blood Pressure in Patients With Atrial Fibrillation
Kim, Daehoon,Yang, Pil-Sung,Kim, Tae-Hoon,Jang, Eunsun,Shin, Hyejung,Kim, Ha Yan,Yu, Hee Tae,Uhm, Jae-Sun,Kim, Jong-Youn,Pak, Hui-Nam,Lee, Moon-Hyoung,Joung, Boyoung,Lip, Gregory Y.H. Elsevier 2018 JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY - Vol.72 No.11
<P><B>Abstract</B></P> <P><B>Background</B></P> <P>The 2017 American College of Cardiology/American Heart Association (ACC/AHA) Guideline for High Blood Pressure in Adults redefined hypertension as systolic blood pressure (BP) ≥130 mm Hg or diastolic BP ≥80 mm Hg. The optimal BP for patients with atrial fibrillation (AF) is uncertain.</P> <P><B>Objectives</B></P> <P>The goal of this study was to investigate the impacts of the 2017 ACC/AHA guideline and to determine the ideal BP threshold for the management of high BP in patients with AF.</P> <P><B>Methods</B></P> <P>This study analyzed data for 298,374 Korean adults with oral anticoagulant–naive, nonvalvular AF obtained from the National Health Insurance Service database from 2005 to 2015.</P> <P><B>Results</B></P> <P>According to the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure guideline, 62.2% of the individuals in our sample had hypertension. After applying the 2017 ACC/AHA guideline, 79.4% had hypertension, including 17.2% with newly redefined hypertension (130 to 139/80 to 89 mm Hg). Those with newly redefined hypertension had greater risks of major cardiovascular events (hazard ratio: 1.07; 95% confidence interval: 1.04 to 1.10; p < 0.001), ischemic stroke, intracranial hemorrhage, and heart failure admission, compared with nonhypertensive patients (<130/80 mm Hg). Among patients with AF undergoing hypertension treatment, patients with BP ≥130/80 mm Hg or <120/80 mm Hg were at significantly higher risks of major cardiovascular events than patients with BP of 120 to 129/<80 mm Hg.</P> <P><B>Conclusions</B></P> <P>Patients with AF and newly redefined hypertension according to the 2017 ACC/AHA guideline were at higher risk of major cardiovascular events, suggesting that the new BP threshold is beneficial for timely diagnosis and intervention. BP of 120 to 129/<80 mm Hg was the optimal BP treatment target for patients with AF undergoing hypertension treatment.</P> <P><B>Central Illustration</B></P> <P>[DISPLAY OMISSION]</P>
Deok-Gyu Kim,Jae-Hwan Park,Jae-Lip Kim,Bong-Kwang Jung,Sarah Jiyoun Jeon,Hyemi Lim,Mi Youn Lee,Eun-Hee Shin,Terry A. Klein,Heung-Chul Kim,Sung-Tae Chong,Jin-Won Song,Luck-Ju Baek,Jong-Yil Chai 대한기생충학열대의학회 2015 The Korean Journal of Parasitology Vol.53 No.1
A total of 1,708 small mammals (1,617 rodents and 91 soricomorphs), including Apodemus agrarius (n = 1,400), Microtus fortis (167), Crocidura lasiura (91), Mus musculus (32), Myodes (= Eothenomys) regulus (9), Micromys minutus (6), and Tscherskia (= Cricetulus) triton (3), were live-trapped at US/Republic of Korea (ROK) military training sites near the demilitarized zone (DMZ) of Paju, Pocheon, and Yeoncheon, Gyeonggi Province from December 2004 to December 2009. Small mammals were examined for their intestinal nematodes by necropsy. A total of 1,617 rodents (100%) and 91 (100%) soricomorphs were infected with at least 1 nematode species, including Nippostrongylus brasiliensis, Heligmosomoides polygyrus, Syphacia obvelata, Heterakis spumosa, Protospirura muris, Capillaria spp., Trichuris muris, Rictularia affinis, and an unidentified species. N. brasiliensis was the most common species infecting small mammals (1,060; 62.1%) followed by H. polygyrus (617; 36.1%), S. obvelata (370; 21.7%), H. spumosa (314; 18.4%), P. muris (123; 7.2%), and Capillaria spp. (59; 3.5%). Low infection rates (0.1-0.8%) were observed for T. muris, R. affinis, and an unidentified species. The number of recovered worms was highest for N. brasiliensis (21,623 worms; mean 20.4 worms/infected specimen) followed by S. obvelata (9,235; 25.0 worms), H. polygyrus (4,122; 6.7 worms), and H. spumosa (1,160; 3.7 worms). A. agrarius demonstrated the highest prevalence for N. brasiliensis (70.9%), followed by M. minutus (50.0%), T. triton (33.3%), M. fortis (28.1%), M. musculus (15.6%), C. lasiura (13.2%), and M. regulus (0%). This is the first report of nematode infections in small mammals captured near the DMZ in ROK.