유화처리 바이오디젤이 도포된 콘크리트의 침투깊이 판정

백철 ( Baek Cheol ),김태우 ( Kim Tae-woo ),이재진 ( Lee Jae-jin ),이동윤 ( Lee Dong-yun ),한민철 ( Han Min-cheol ),한천구 ( Han Cheon-goo ) 한국건축시공학회 2017 한국건축시공학회 학술발표대회 논문집 Vol.17 No.2

This study is to provide a evaluation method for the penetration depth of emulsified refined bio diesel(ERBD)applied to a surface of the concrete by using water absorption capability of the concrete. The concrete applied with ERBD was immersed at water for 1 min., 5min., and 10 min. and then was checked the brightness with elapse of time. Test results indicated that there was clear difference between ERBD part and non ERBD part in concrete specimen after measuring the brightness until 120min.

한국인 주의력결핍 과잉행동장애 아동에서 도파민 D4 수용체 유전자의 Variable Number of Tandem Repeats (VNTR) 다형성과 Methyphenidate 치료 반응간의 연관성

천근아,김붕년,조수철,김재원,황준원,신민섭,홍강의 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : In the present study, we investigate the association between homozygosity of the 4-repeat allele (4/4) at the DRD4 and the response to the treatment with MPH in Korean children with ADHD. Methods : The present study included 71 children with ADHD (8.231.78 years) from two children's psychiatric clinics in South Korea. All drug-naive children with ADHD were treated with MPH for about 8 weeks. The subjects who showed improvement of over 50% compared with the baseline ARS score after 8 weeks of treatment were termed as the 'good response' group. The subjects who showed an improvement of less than 50% were considered as the 'poor response' group. After genotyping for DRD4 were performed, we investigated correlation between homozygosity for 4-repeat allele at DRD4 and the response to MPH treatment. Results : We found that while 79.5% (31/39) of the subjects with homozygosity of 4-repeat allele at DRD4 showed good response to MPH treatment, 68.8% (22/32) of the subjects without homozygosity of 4-repeat allele at DRD4 showed poor response to MPH treatment according to ARS scores assessed by their parents (χ²= 16.762, df= 1, p<0.01). We also found that while 61.5% (24/39) of the subjects with homozygosity of 4-repeat allele at DRD4 showed good response to MPH treatment, 87.5% (28/32) of the subjects without homozygosity of the 4-repeat allele at DRD4 showed poor response to MPH treatment according to ARS scores assessed by their teachers (χ²= 17.698, df= 1, P<0.01). Conclusion : Our findings support an association between the homozygosity of 4-repeat allele and a good response to MPH in ADHD of Koreans.

본태성 고혈압쥐의 성장에 따른 뇌신경 세포막 Na, K-ATPase변동에 관한 연구

류석천,허강민,석정호,이재흔 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.1

To investigate the development change of synaptosomal Na, K-ATPase of hypertensive rat, Na, K-ATPase activity and ouabain binding sites were measured in the synaptosomal membrane prepared from 3 days-, 2 weeks-, 20 weeks- old Sprague-Dawley rats and spontaneously hypertensive rats Resulrs are as follows; 1. in the synaptosomal Na, K-ATPase of the normotensive and hypertensive rats, there were 2 kinds of isozymes, high affinity site(IC_(50):80-260 nM) and low affinity site(IC_(50):30-60 μM) 2. Synaptosomal Na, K-ATPase activity was increased in 2 and 20 weeks(high affinity site) or 2 weeks(low affinity site) old compared to that in 3 days old rat, and showed a tendency of decrease in 33 weeks old compared to that in 20 weeks old rats(high affinity site) in both groups. 3. Synaptosomal Na, K-ATPase activities of hypertensive rats were low in 3 days and 2 weeks old(high affinity site) or 3 days old (low affinity site) compared to that age groups of normotensive rats. 4. In the ouabain binding experiments, Kd value(0.1-0.2 μM) for ouabain was slightly increased with increase of age, but no difference between normotensive and hypertensive rats was detected. 5. The numbers of ouabain binding sites were increased in 2 weeks and 20 weeks old compared to those in 3 days old rats, and showed a tendency of decrease in 33 weeks old compared to that in 20 weeks old rats. 6. In the hypertensive rats, the number of ouabain binding sites was low in 3 days, compared to that of the correponding age group of normotensive rats. From the above results, it is suggested that in the spontaneously hypertensive rat, 1) synaptosomal Na, K-ATPase of high affinity site or low affinity site is increased significantly after birth as well as in the normotensive rat, 2) but significantly less than that of normotensive rats in early periods after birth and this may due to the low concentration in both high and low affinity Na, K-ATPase isozymes for ouabain.

Transarticualr portal를 이용한 주관절의 관절경술

김성재,박인섭,김주영,정재훈,류상욱,천용민 대한견.주관절학회 2003 大韓肩.주關節學會誌 Vol.6 No.2

거대적아구성빈혈의 임상적 고찰

곽승근,천재민,박남숙,박상은,박수진,윤환중,김삼용,조덕연 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

Megaloblastic anemias are disorders caused by impaired DNA synthesis and chara-cterized by the presence of megaloblastic cells. Clinical data on these disorders in Korea are limited. The aim of this study was to analyze clinical characteristics of megaloblastic anemias caused by vitamin B12 deficiency. We identified 40 cases who were diagnosed as megaloblastic anemia from January 1993 to December 2002 in a retrospective study on the basis of chart review. We investigated the annual distribution of diagnosed patients, clinical manifestations and response to treatment. 19 cases were complicated with a previous total gastrectomy(gastrectomy group) and 21 cases had no history of surgical operation(non-gastrectomy group). The most common presenting complaint was generalized weakness. The median age at diagnosis was 7(range: 38-79) years in non-gastrectomy group. The mean pos-toperative duration was 7(range: 4-25)years in group of total gastrectomy and mean level of serum vitamin B12 was lower than 100 pg/mL in both group. Peripheral blood revealed thrombocy-topenia, macrocytic anemia and hypersegmented neutrophil in all cases. After treatment of pareliteral vitamin B12, Their clinical symptoms and hematologic findings improved except two patients who had bone marrow with lower cellularity. Cobalamin replacement after total gastrectomy is still missing. Diagnoses are made too late in a population of patients, resulting in irreversible neurological sequale, and we suggest that Pernicious anemia seems not to be very rare in Korea.

전기비저항을 이용한 금속합금 열화도 평가기술

남승훈,유광민,류제천 한국비파괴검사학회 2001 한국비파괴검사학회지 Vol.21 No.5

재료의 노화에 의한 강도 및 인성 감소치를 정량적으로 평가하는 비파괴적 기법의 개발이 시도되고 있으며 전기비저항법도 그 중의 하나이다. 본 연구에서는 전기비저항법의 열화도 평가에의 적용성을 살펴보기 위해 먼저 6종 10 가지의 비자성 금속을 측정시료로 선택하여 직류 two-point probe법(혹은 2탐침법)으로 전기비저항을 계산한 결과와 비접촉식 와전류 방법으로 전기비저항을 측정한 결과를 서로 비교하였다. 또한, 1Cr-1Mo-0.25V강에 대하여 비파괴적 측정 방법인 four-point probe 방법(혹은 4탐침법)을 사용하여 얻은 결과와 기존의 2탐침법을 사용하여 얻은 결과를 서로 비교하여 현장에서의 4탐침 기술의 적용 가능성을 살펴보았다. 1Cr-1Mo-0.25V강에 대하여 2탐침법으로 구한 비저항값과 4탐침법으로 구한 비저항 측정값의 차이는 0.6%였다. 따라서 4탐침법을 사용하여 현장에서 금속소재의 열화도의 비파괴적 평가가 가능하다고 사료된다. Developments of nondestructive evaluation techniques for reduction of strength or toughness by aging of material have been carried out, and the method using electrical resistivity is one of them. In this study, to examine the application of electrical resistivity to the evaluation of the evaluation of degradation of metallic alloy, ten different non-magnetic materials were selected as test materials. Electrical resistivities measured by DC two-point probe method and those measured by non-contact type eddy current method were compared with each other. In addition, to examine the application possibility of four-point probe technology in field, the electrical resistivities for 1Cr-1Mo-0.25V steel measured by DC two-point probe method and four-point probe method were compared with each other. Differences between two measure values for the 1Cr-1Mo-0.25V steel were0.6%. Therefore, the four-point probe method can be applied to the estimation of the degradation of metallic alloy.ect.

한라산 경사면의 일사량 및 기온 추정 모형

이종범,이민영,최재천 江原大學校 附設 環境硏究所 1991 環境硏究 Vol.8 No.-

A prototype air temperature and solar irradiance simulation model was developed to predict the distribution pattern over the slope of Mt. Halla in Chejudo. The model is based on potential effects of major topo-geographical factors on hourly air temperature derived from principal component analysjs multiple regression analysis. Although the model outputs were not validated yet, the precision based on 1km by 1km grid and small RMS error show a feasibility for practical applications to diverse economic activities in Cheju Island.

Synthesis and biodistribution of ¹⁸F-labeled α-, β- and ω-fluorohexadecanoic acid

Lee, Yun-Sang,Kim, Young Joo,Cheon, Gi Jeong,Jeong, Jae Min Korean Society of Radiopharmaceuticals and Molecul 2018 Journal of radiopharmaceuticals and molecular prob Vol.4 No.2

${\omega}-[^{18}F]$-Fluorohexadecanoic acid (FHA) has been used for imaging of fatty acid metabolism of myocardium. To increase retention of radiolabeled fatty acid by blocking ${\beta}$-oxidation, methyl branched analogues have been used. In this experiment, we tried to synthesize 18F-labeled ${\alpha}-$, ${\beta}-$ and ${\omega}-FHA$ for imaging of the myocardial fatty acid metabolism. We synthesized ${\alpha}-$, ${\beta}-$ and ${\omega}$-mesylated methyl hexadecanoates and labeled with $^{18}F$ by reacting with $[^{18}F]$TBAF in acetonitrile at $80^{\circ}C$ for 10 min. Methyl ester group was removed by 1 M NaOH at $80^{\circ}C$ for 5 min. The yields of ${\alpha}-[^{18}F]$ and ${\omega}-[^{18}F]FHA$ were 25.5 and 45.5%, respectively [EOS]. However, ${\beta}-[^{18}F]FHA$ was not labeled at all due to a fast elimination reaction. The biodistribution study in ICR-mice showed that ${\omega}-[^{18}F]FHA$ has higher myocardial uptake and lower liver uptake than ${\alpha}-[^{18}F]FHA$. The electron-withdrawing effect of fluorine at ${\alpha}-$ position is believed to be the major factor affecting the biodistribution.

부비동 악성 종양의 임상적 분석

백병준,유명상,신재민,김효진,박훈,김장묵,오천환 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.2

Background and Objectives : Paranasal sinus cancer is rare when compared with cancers of other sites. Because paranasal sinus is anatomically located adjacent to the orbit and skull base, it is difficult to remove the tumor completely with tumor free margin in advanced paranasal sinus cancer. This report was conducted to investigate clinical characteristics, histologic type and treatment outcome of paranasal sinus cancer. Material and Methods : Twenty-six cases with paranasal sinus cancer diagnosed at the Department of otolaryngology-Head and Neck Surgery, Soonchunhyang Cheonan Hospital from January 1991 to September 2000 were studied by chart review, telephone interview and letters retrospectively. Results : The male to female ratio was 4.2 : 1. Most patients were 6th and 7th decade. The maxillary sinus was the most commonly affected site(61.5%), followed by the ethmoid sinus(34.6%). The most common histologic type of malignancy was squamous cell carcinoma(57.6%), followed by adenocarcinoma(19.2%). Most patients presented with T_(3)/T_(4) or locally advanced disease, N_(0)(91.3%), and M_(0)(100%) Sixtynine pertcent of this study group underwent sugery as part of a mutimodality curative treatment plan or alone as curative treatment. Eighteen patients(69.2%) developed recurrent disease at a median time of 278 days after initial treatment. Kaplan-Meier analysis revealed the 5-year disease specific survival was 34.6%. Conclusion : Most patients with paranasal sinus cancer presented with locally advanced disease. Adanced T stage was highly predictive of poor prognosis. Recurrence rate was high and mostly occured within the second year after treatment.

기도 이물의 임상적 고찰

김영석,이승규,이민재,백병준,오천환 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.2

Aspiration of foreign bodies into the airway is a common problem in spite of efforts to educate the public and it can be sometimes fatal accidents. A retrospective study has been performed for 34 cases of airway foreign bodies, which were obtained from April 1994 to August 1998 at Chunan hospital of Soonchunhyang University. The results were as follows: 1) Among the 34 cases, 26 cases(76.4%) were under the age of 3. The ratio of male and female was 1.4:1. 2) The most common symptom after foreign body aspiration was intractable cough(38.2%). 3) Abnormal findings in the chest X-ray films were found 24 cases(70.6%) and the most common abnormal radiologic feature was combination of pneumonia and atelectasis(37.5%), followed by combination of pneumonia and emphysema(16.6%), pneumonia alone(16.6%). 4) The nature of foreign body was vegetables in 20 cases(58.8%), miscellaneous in 11 cases(32.4%), metals in 2 cases(5.9%) and plastics in 2 cases(5.9%). 5) By distribution of the location of foreign bodies, 26 cases(76.4%) were located in the main bronchus(20 cases in right side and 6 cases in left side), 5 cases were in trachea, 2 cases were in larynx and 1 case was located at carina level. 6) By duration of foreign body lodgement in the airway, 15 cases(44.1%) were found within 24 hours, 9 cases(26.5%) were within 7 days, 7 cases(20.6%) were within 30 days and 3 cases(8.8%) were found over 1 month. 7) In mode of treatment, ventilating bronchoscopic removal under general anesthesia was performed in 29 cases(85.3%), thoracotomy with bronchotomy in 2 cases, thoracotomy with lobectomy in 1 case and postural drainage in 2 cases. 8) Complication rate according to the nature of foreign body was most high in vegetables(68.2%). 9) Correlation between complication rate and the duration of the foreign bodies in situ was definite.