인체 지방 및 간장조직 중 유기염소제류의 확인 및 정량기법 체계화

이상기,양자열,인상환,김기욱,이수연,오승민,김미영,정규혁 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-

인체 지방 및 간장조직 중 유기염소제류 및 PCB의 확인 및 정량기법 체계화 : 2차년도

이상기,양자열,김기욱,이수연,오승민,김대현,정규혁 內務部 國立科學搜査硏究所 2002 國立 科學 搜査 硏究所 年報 Vol.34 No.-

한국인 모발과 내부장기조직간 Cd, Hg, Pb 및 Zn함량의 상호관련성

유영찬,이상기,양자열,김기욱,이수연,정규혁 한국환경독성학회 2002 환경독성보건학회지 Vol.17 No.1

In order to study the relationships between trace element concentrations of hair and internal organs, autopsy samples of hair, liver, kidney cortex, kidney medulla, heart, lung, spleen, cerebrum, testis and bone from 162 Korean subjects were analyzed for Cd, Hg, Pb and Zn by inductively coupled plasma atomic emission spectrometry. High significant positive correlations were found between the Cd concentration in hair and bone and Pb in hair and lung. Hair Hg levels were highly significantly correlated with organ Hg levels in the liver, kidney cortex, kidney medulla, heart, lung, spleen, cerebrum, testis and bone. And hair Zn levels were highly significantly correlated with organ Zn levels in the kidney cortex, kidney medulla, spleen, testis and bone.

녹농균의 혈청형에 관한 연구

서인수,조양자,정용훈,이열 한양대학교 의과대학 1987 한양의대 학술지 Vol.7 No.2

The rabbit anti-group sera against thirteen representative standard strains of Pseudomonas aeruginosa, A to M groups were prepared for preparation of serological diagnostic factor. Using the grouping sera for both slide and tube methods, the agglutination reaction has been carried out for each of the thirteen groups of viable and various killed cells of Pseudomonas aeruginosa, A to M groups as agglutinogens to obtain the following results: 1. Of the thirteen anti-group sera eleven showed highly specific antisera for serological typing on the slide agglutination regardless of ind of agglutinogens i.e., viable, thermostable, thermolabile or formalized cells. 2. When serologicalcross reaction of the standard group strains with each of the anti-sera was estimated by using agglutination reaction, the anti-G group serum showed ?? To ?? Intensity of cross reaction with the viable cells of A, F and J grouping. 3. The viable cells of F group were reacted with all anti-group sera except one. 4. The thermostable agglutinogen (120℃, 2hr) of group F strain gave no cross reaction with any of the thirteen anti-group serum. By contrast group M showed the cross reactivity with almost all of the anti-sera. 5. In the course of the immunization, of the thirteen groups, the agglutinin titers of each of anti-group sera, except for the thermolabile antigen were highest in two weeks after immunization by tube method. 6. Of the standard groups strains the group E was highly immunogenic. The anti-E serum showed agglutinin titer 2,560 times more than other groups for various agglutinogens as mentioned previously. The agglutinin titers of anti-C, -D, -D and -K group sera were shown even at 1,280 to 2,560 times dilution when thermostable antigens were used. In case of thermolabile antigens, however, the above titers were not appreciable at 20 times dilution. 7. In the titration of the agglutinins of 0 antigen of Pseudomonas aeruginosa, A to M groups, the thermostable antigens were most sensitive agglutinogen, while the thermolabile antigens were lowest in sensitivity.

마우스 단위법에 의한 테트로도톡신 중독사 판정사례(제2보)

정희선,김은미,김인숙,양자열 內務部 國立科學搜査硏究所 1996 國立 科學 搜査 硏究所 年報 Vol.28 No.-

Soluble c‐Met protein as a susceptible biomarker for gastric cancer risk: A nested case‐control study within the Korean Multicenter Cancer Cohort

Yang, Jae Jeong,Yang, Ji Hyun,Kim, Jungkon,Ma, Seung Hyun,Cho, Lisa Y.,Ko, Kwang‐,Pil,Shin, Aesun,Choi, Bo Youl,Kim, Hyun Ja,Han, Dong Soo,Eun, Chang Soo,Song, Kyu Sang,Kim, Yong Sung,Chang, Sou Wiley Subscription Services, Inc., A Wiley Company 2013 International journal of cancer: Journal internati Vol.132 No.9

<P><B>Abstract</B></P><P>This study was conducted to evaluate the relevance of the soluble form of c‐Met protein, a truncated form of the c‐Met membrane receptor involved in the CagA pathway, as a potential biomarker for gastric cancer. Among 290 gastric cancer case‐control sets selected from the Korean Multicenter Cancer Cohort, the plasma concentrations of soluble c‐Met protein were measured with enzyme‐linked immunosorbent assays. Using analysis of variance and covariance models with age, sex, smoking, <I>Helicobacter pylori</I> infection, and CagA seropositivity, the mean concentrations of soluble c‐Met protein between cases and controls were compared. To evaluate the association between gastric cancer and a c‐Met protein level, odds ratios and 95% confidence intervals were estimated using conditional logistic regression models. Interactions between CagA‐related genes and the soluble c‐Met protein concentration were also investigated. The overall median plasma concentration of soluble c‐Met among cases was significantly lower than those of controls (1.390 <I>vs</I>. 1.610 ng/mL, <I>p</I> < 0.0001). Closer to the onset of gastric cancer, the soluble c‐Met protein level decreased linearly in a time‐dependent manner (<I>p</I> for trend = 0.0002). The combined effects between the CagA‐related genes and the soluble c‐Met protein concentration significantly intensified risks for gastric cancer. Restricted analyses including cases that had been diagnosed within 1 year after entering the cohort had a fair degree of ability (area under the receiver operating characteristic curve of 0.73–0.77) to discriminate gastric cancer cases from normal controls. Our findings demonstrate the potential of the soluble form of c‐Met protein as a novel biomarker for gastric cancer. The beneficial effects of a high soluble c‐Met concentration in human plasma are strongly supported.</P>

유아문해교육에 대한 교사의 인식과 실태 분석

양자인(Ja-In Yang),배율미(Youl-Mi Bae) 중앙대학교 한국교육문제연구소 2014 한국교육문제연구 Vol.32 No.1

본 연구의 목적은 유아문해교육에 대한 교사의 인식과 유아교육현장의 문해교육 실태를 조사하는 것이었다. 연구대상은 서울시, 경기도, 광주광역시, 부산광역시, 울산광역시, 전라도, 충청도 지역의 어린이집 및 유치원에 재직하고 있는 유아교사 373명이었다. 교사의 인식과 실태에 대한 자료를 수집하기 위해 설문지를 개발하여 사용하였다. 수집된 자료는 카이검증(χ²-test)을 통해 분석하였다. 연구결과, 문해교육 수행에 적절한 연령으로 대부분의 교사들이 만 3세부터 시작하는 것이 가장 적절하다고 인식하고 문해교육 수행 이유는 대부분의 교사들이 유아들의 흥미와 발달상 중요하다는 인식 때문인 것으로 나타났다. 문해교육과 가장 효과적으로 연계하여 가르칠 수 있는 영역으로는 누리과정 중 사회관계 영역을 가장 많이 인식하였다. 문해교육 교사연수 필요성에 대해서는 대부분의 교사들이 문해교육 교사연수가 필요하다고 인식하였다. 문해교육 수행 횟수와 시간에 대해 대부분의 교사들이 문해교육을 주 1∼2회, 하루 일과 중 항상 하는 것으로 가장 많이 응답하였고 문해교육 교재교구 구비 실태와 문해교육 자료준비 실태에 대해서는 보통이라고 응답하였다. 본 연구를 통해 유아교육자들이 유아문해교육을 보다 효과적으로 실행할 수 있도록 돕는 기초자료를 제공하고자 한다. The purpose of this study was to investigate teachers’ awareness and the status of literacy education for young children in the field of early childhood education. The subjects were 373 early childhood teachers at the care centers and preschools in Seoul, Gyeonggi-do, Gwangju, Busan, and Ulsan metropolitan cities, Jeolla-do, and Chungcheong-do. A survey was developed and used to collect data of teachers’ awareness and status of literacy education. Chi-square test (χ²-test) was used to analyze the collected data. The results were as follows. First, most teachers were aware that the most proper time to begin literacy education for young children was at the age of three; the importance of children’s interest and development was a reason for implementing literacy education in early childhood; a domain of social relationship among Nuri curriculum can be most effectively taught when connecting literacy education and the curriculum; and in-service teacher training related to literacy education was needed. Second, related to frequency and time of literacy education implementation, most teachers answered that they provided literacy education to their children 1-2 times per week and every time in daily routines; the statuses of teaching material requirements and preparation of general materials were neutral. This study provides fundamental information for helping early childhood educators to implement more effective literacy education for young children.

유·무선 인터넷 서비스가 가능한 맞춤형 비빔밥 콘텐츠 설계

장대자(Dai-Ja Jang),양혜정(Hye Jeong Yang),권대영(Dae Young Kwon),성우열(Woo-Youl Sung) 한국콘텐츠학회 2010 한국콘텐츠학회논문지 Vol.10 No.7

본 연구에서는 PC 웹상에서만 제공되던 음식정보를 모바일에서도 동일하게 서비스가 가능한 콘텐츠를 설계하였다. PC와 모바일에서 동시에 서비스되는 웹 사이트는 회원 정보를 통해 각 개인에게 맞는 음식정보를 중심으로 콘텐츠를 서비스가 가능하도록 설계하였다. 이 콘텐츠를 통해 제공된 정보를 모바일 사용자가 실제 적용할 수 있도록 함으로써 각 개인의 건강관리에 도움을 줄 수 있도록 하였다. 이 시스템에서는 무선 인터넷이 가능한 모바일을 사용하는 사람들을 대상으로 하며, 여러 음식 메뉴 중에서도 비빔밥과 관련된 식자재 정보와 각 개인에게 맞는 레시피 그리고 조리 동영상을 제공할 수 있도록 하였다. 한국 전통 음식 중 하나인 비빔밥은 여러 가지 생채류와 나물들로 구성되어 영양적으로도 균형 있는 음식으로도 잘 알려져 있다. 이는 유·무선 인터넷 서비스가 가능한 웹 사이트 설계로 어느 곳에서든지 사용자들이 모바일의 무선인터넷을 이용하여 몸에 좋은 식품 정보, 건강을 위한 메뉴와 같은 콘텐츠를 제공받을 수 있도록 하는 것이다. In this research a food information contents available as well as for PC web and for mobile web users was designed. The web site providing service for PC web and mobile web clients focuses on offering data on individually matching food based on the member’s information. The information obtained from the contents can be practically applied by mobile users helping them to take care of their health. This system focuses on wireless internet mobile users and offers various food menus with cooking videos and also information regarding food supplies for individually matching bibimpab recipes. It gives a good information about one of the most traditional Korean food bibimpab which is made of various kinds of vegetables and greens. It also contains nutrition balance information. Designing the web site as a web site available for wired·wireless internet accesses makes it available at any place for mobile wireless internet users so that they can obtain all information regarding products and menu which are good for their health.

Fatal poisoning cases due to benfuracarb or furathiocarb ingestion

Sang Ki Lee,Ja Youl Yang,Ki Wook Kim,Mee Jung Park,Yoo Sin Park,Hee Sun Chung,Young Chan Yoo 환경독성보건학회 2005 한국독성학회 심포지움 및 학술발표회 Vol.- No.-

생약류중에서 중금속의 함량에 관한 연구

이상기,양자열,인상환,김기욱,구기서 내무부 국립과학수사연구소 1999 國立科學搜査硏究所年報 Vol.31 No.-