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- 저자 : Iswar, Riezka Rivani (검색결과 3 건)
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Hazarika Iswar,Mukundan Geetha Kannoth,Sundari Sivakami P.,Das Anju 경희대학교 융합한의과학연구소 2022 Oriental Pharmacy and Experimental Medicine Vol.22 No.1
Hydrocotyle sibthorpioides Lam. (Family: Araliaceae) is used widely in the preparation of food in different cuisines of the world. The study was designed to explore the protective effect of different standardised extracts of H. sibthorpioides on the AlCl3 induced neurotoxicity in Alzheimeric rats. When AlCl3 at a dose of 100 mg/kg body weight was administered i.p. for 60 days showed a significant increase in aluminium (Al) level, acetylcholinesterase (AChE) level and protein expressions of amyloid precursor proteins, β and γ secretase, and β-amyloid (Aβ1–42) in the cortex and hippocampus comparing to the control. Moreover, there was a significant reduction in locomotor activity, muscle coordination and cognition and memory. On the other hand, animals treated with chloroform and methanolic extracts of H. sibthorpiodes given at 200 and 100 mg/ kg body weight orally with AlCl3 altered the behavioural impairment caused by Al and Al concentration, activity of AChE, synthesis molecules of Aβ generation. The report of histological studies in hippocampus and cortex supported the neuropro- tective role of chloroform and a methanolic extract of H. sibthorpioides, which conserved a normal histoarchitecture pattern of cortex and hippocampus. Finally, it can be concluded that chloroform and methanolic extract of H sibthorpioides can alter memory loss induced by aluminum toxicity by enhancing AChE activity and by its involvement in amyloidogenic pathway.
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Sailendra Dewan,Iswar Kumar Chettri,Kishor Sharma,Bhoj Kumar Acharya 한국응용곤충학회 2019 Journal of Asia-Pacific Entomology Vol.22 No.2
The lowland areas of the Himalayan region are subjected to immense anthropogenic pressure because of least representation in the protected area network. Kitam Bird Sanctuary is the only representative protected area that occurs below 1000 m in Sikkim state of India (a part of globally significant biodiversity hotspot of Himalayas) and serves as the refuge for various species of flora and fauna. Here we studied butterfly diversity and community composition in Kitam Bird Sanctuary (a small protected area of 6 km 2 geographical area) following point count method spread across predetermined transects. Altogether 1674 butterflies belonging to 111 species and six families were recorded after completion of 240 point counts. Among these, 18 species are federally protected under the Wildlife (Protection) Act (1972) of India. Most of the butterflies were forest specialist in terms of habitat preference, whereas based on host plant specificity, the butterfly community was mostly dominated by generalist feeder (Oligophagous II and Polyphagous). Butterfly community parameters showed a strong correlation with habitat variables. While Kitam Bird Sanctuary is primarily designated for conservation of lowland birds, the high diversity of butterflies both in terms of taxonomic richness and trait composition suggests that the sanctuary harbors an ideal habitat for butterflies of the tropical region and invites conservation attention.
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Histopathological Features of Lymphoma in Yogyakarta, Indonesia
Dwianingsih, Ery Kus,Indrawati, Indrawati,Hardianti, Mardiah Suci,Malueka, Rusdy Ghazali,Iswar, Riezka Rivani,Sutapa, Stefani APPG,Triningsih, FX Ediati Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.9
The incidence and prevalence, the second most common lymphoid malignancy after leukemia, are both increasing. The distribution of lymphoma varies among sexes, age groups, and sites. In Indonesia, information about the incidence of lymphoma and its characteristics are insufficient. Therefore, this study was performed to evaluate the incidence of lymphoma and features based on age group, sex, site, clinical diagnosis, and histopathological type in Indonesia. This study is an observational analytical study with a cross-sectional design aimed to evaluate the histopathological profile of lymphoma in Yogyakarta from 2010-2014. It was based on secondary data from Anatomic Pathology Department's medical records from several hospitals and laboratories. The result showed an increased incidence of lymphoma in Yogyakarta in 2010-2014 (p=0.039). Lymphoma mostly occurred in age range 45-64 years (p=0.004), dominated by male with ratio 1.6:1. DLBCL was found to be the most common histopathological type (44.4%). Sex, age, and clinical diagnosis demonstrated statistically significant correlations with the histopathological type (p<0.001). In conclusion, the incidence of lymphoma has significantly increased from 2010-2014. There are statistically significant correlations between gender, age, and clinical diagnosis with the histopathological type of lymphoma.
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