간세포암과 감별이 어려웠던 악성중피종 치험 1예

김선문,허원석,채경훈,강윤세,정재훈,김연수,박기오,문희석,이엄석,김석현,성재규,이병석,이헌영,신경숙,조준식,송인상,강대영 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

Malignant peritoneal mesothelioma is a rare neoplasm that arises from the mesothelium of a serosal cavity and is a rapidly fatal disease with a median survival of 4 to 12 months for untreated cases. Recently, we experienced a case with malignant peritoneal mesothelioma who was suspected hepatocelluar carcioma by abdominal CT scan and was confirmed by biopsy including immunohistochemical stain(calretinin) after surgery. We performed tumor excisions and wedge resection of the liver(segment Ⅷ)and inserted Tencoff catheter in abdominal cavity at 25th day of post-operation. We treated with intraperitoneal paclitaxel(25mg/m^(2)/day for 5 days) six courses monthly. She was well tolerable and is still living without any evidence of recurrence for 14th month of post-operation.

Gilbert 증후군에서 열량 제한 시험과 Phenobarbital 자극 시험의 의의(14예)

이헌영,채경훈,정재훈,강윤세,김연수,문희석,박기오,이엄석,김선문,김석현,성재규,이병석,이강욱 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

Gilbert 증후군은 인구의 7%에서까지 나타날 수 있는 매우 흔한 증후군으로서 비진행성인 양성의 만성적 경과를 치하며, 간질환의 증상과 징후가 없는 경한 비포합형 고빌리루빈혈증이 특징인 일종의 체질적인 증상으로서 혈장 빌리루빈 농도에 대한 사춘기의 영향 때문에 10대와 20대에 자주 진단이 된다. 따라서 임상적인 중요성은 미약하지만 높은 빈도가 예상되는 점에 그 중요성이 부여되어야 할 것이다. 따라서 적정한 임상적 진단법으로 기왕에 소개된 열량제한 시험과 phenobarbital 유도 시험을 시행하고 이들의 진단적 가치를 알아보기 위하여 본 연구를 시행하였다. 1990년 7월부터 1999년 4월까지 충남대학교병원에 내원하여 HBsAg, IgG anti-HBc 및 anti-HCV가 음성이고, 간 초음파 스캔에서 이상이 없으며, 혈청 AST, ALT 및 AP가 정상인 비음주자에서 경한 비포합형 고빌리루빈혈증이 있는 14예의 환자들을 대상으로 ^(99m)Tc-DISID 스캔을 시행하였으며, 기저 치 총빌리루빈 및 포합형 빌리루빈 치를 측정한 다음에 하루에 400Kcal로 48시간동안 제한한 열량 제한 시험을 시행하였고, phenobarbital을 하루 60mg씩 5일간 투여한 후에도 각각 총빌리루빈과 포합형 빌리루빈 치를 검사하여 비포합형을 구하였다. 대상 환자들은 모두 14예로서 남자가 11예(78.6%)였고 여자가 3예(21.4%)여서 3.7:1로 남자에서 많았으며, 20대가 6예(42.9%), 30대가 역시 6예(42.9%) 및 40대가 2예(14.2%)로서 2,30대가 대부분(85.8%)이었다. 열량 제한 시험 후의 총빌리루빈 치, 비포합형 및 포합형 빌리루빈 치들은 평균 각각 5.5±2.7, 4.2±2.3 및 1.3±10mg/dL 로서, 시험 전 치들인 3.0±0.8, 2.2±0.8 및 0.7±0.4mg/dL 보다 유의하게(p=0.001, p=0.001, p=0.023) 상승하였다. 포합형 빌리루빈 치도 유의하게 상승하였으나 비포합형의 상승보다는 훨씬 낮아서 주로 비포합형이 증가하였다. phenobarbital 투여 중 설사가 발생하여 중단한 1예를 제외한 13예에서 열량 제한 시험 후에 상승하였던 총, 비포합형 및 포합형 빌리루빈 치가 phenobarbital 유도 시험후에는 2.0±1.1, 1.5±0.8 및 0.5±0.4mg/dL로서 열량 제한 시험 결과보다 유의하게 낮아졌고(p=0.00, p=0.000, p=0.001), 열량 제한 시험 전의 기초치들인 3.0±0.8, 2.2±0.8 및 0.7±0.4mg.dL 보다도 더욱 낮아졌으며 유의한 차이(p=0.001, p=0.02, p=0.005)를 나타내었다. 14예에서 시행한 ^(99m)-Tc DISIDA 스캔에서 9예(64.3%)가 정상이었고, 5예(35.7%)에서는 심장 및 신장으로의 간외 섭취가 3예였고, 60분까지 소장 배출이 없는 배설 지연 예와 담낭 수축 불량 예가 각각 1예 씩 발견되었다. Phenobarbital 투여시험에서 민감도가 열량제한시험에 비해 더 높았다(92.3%와 50.0%). Gilbert 증후군에서 1일 400 Kcal로 48시간의 열량제한 시험과 1일 60mg의 phenobarbital을 5일간 투여하는 유도 시험은 편리하고 유용한 임상적인 진단법으로 이용할 수 있다고 생각된다. 그러나 열량 제한 시험에서는 증가 기준의 통일이 필요하다고 유추되며 phenobarbital 유도 시험이 민감도가 더 높은 것으로 생각된다. Gilbert's syndrome is very frequent and benign chronic process characterized by mild, intermittent, unconjugated hyperbilirubinemia without any symptom and sign of liver disease. Previously intoduced caloric restriction test and phenobarbital stimulation test as two appropriate clinical tests had been examined and their diagnostic values were reevaluated. Fourteen patients with mild, persistent, unconjugated hyperbilirubinemia were included. Subsequently caloric restriction has been applicated by 400 Kcal/day for 48 hours and phenobarbital has been prescribed by 60 mg/day for 5 days. Therafter serum levels of total and direct bilirubin were measured. Most of the patients were third and fourth decade(85.8%) and male predominant. Each basal serum levels of total, indirect and direct bilirubin were 3.0±0.8, 2.2±0.8 and 0.7±0.4 mg/dL. After caloric restriction test, each levels were increased significantly to 5.5±2.7, 4.2±2.3 and 1.3±1.0 mg/dL(p=0.001, p=0.001, p=0.023). After phenobarbital stimulation test for 13 patients had been practiced, increased levels of each bilirubin after caloric restriction test were decreased significantly to 2.0±1.0, 1.5±0.8 and 0.5±0.4 mg/dL(p=0.000, p=0.000, p=0.001) and these levels were significantly lower than basal levels(p=0.001, p=0.02, p=0.005). The sensitivities of caloric restriction test were 85.7%, 50.0%, and 71.4%, 35.7%(1.0, 1.5 mg increase of total bilirubin and 1.0, 1.5 mg/dL increase of indirect bilirubin). The sensitivities of phenobarbital stimulation test were 93.2% and 92.3% at criteria of 1.5 mg/dL increase of total bilirubin and indirect bilirubin. On the diagnosis of Gilbert syndrome, caloric restriction test and phenobarbital stimulation test are convenient and useful diagnostic tools in clinical face. And also phenobarbital stimulation test has higher sensitivity than caloric restriction test. Furthermore, standardization of bilirubin increment would be necessary in caloric restriction test.

고향상실에 나타난 신화성 : 라스뿌찐의 『마쪼라의 이별』과 문순태의 『징소리』를 중심으로

문석우 한국비교문학회 2003 比較文學 Vol.30 No.-

Some mythical features features could seen in Moon sun-tae's Sound of Jing and Balentin Rasputin's parting from Matyora. It made us understand their works easily in that their motives were analyzed with European myth, Siberian myth and folk myth. The works can be categorized in a unit of myth which underlay to create a brand-new myth by reanalyzing an existing myth. I think that Casireo had a point there he said that a mythical way of thinking was interpreted as an incessant denial of death, an assurance of unity and continuity without severance of life and an ardent affirmation of life. These aspects of myth gave a longevity to literary to literary works Therefore, mythology is the best appropriate way for us to recognize ourselves and deal with a relation between an outside world and ourselves. Seen from a mythological angle on parting from Matyora, Jingsori, they were filled with mythical features such as Matyora and Banhyuljae spatial particularity and mythical prototype. Images of creative myth and eschathological myth in the minds of Siberian people were revealed in Parting from Maryora. Although Balentine Rasputine admitted that there was a posthumous world after death eschatology and left a room for rotation, we could discover that there is a little rotational link. Moon sun-tae described not only exhausting lives of people who lost their own homes with a dam-building project in Japanese in Jangsung district, a sense of crisis and despair with severance of their own history and culture of hometown, but also a hatred for human existence downplayed by a tremendous dam. His works could be interpreted in many ways as an perspective of the new drama. Moon Sun-tae said that he had a deep though about how we could express a reality vividly in a genre of non-fiction. He wanted to feel the same pain as people in hometown did, confront with their own history and bring those in a genre of novel. I think that a mythological motive approach of two novels showed how we did forget ourselves in human nature.

중이, 외이도 및 측두하와에 국한된 편평상피유두종 1예

윤병문,박성원,민경식,홍기수,조미연,양석우 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.7

한국 근대문학에 끼친 뚜르게네프의 영향 : 시인 김억을 중심으로

문석우 조선대학교 외국문화연구소 1994 外國文化硏究 Vol.17 No.1

한국 근대문학 초기의 정치, 사회적 분야에서 개혁의 분위기는 곧 문학전반에도 파급되었다. 1894년 갑오경장(개화기)이후 본격적으로 유입되기 시작한 서구문학의 영향을 받으면서 형성된 근대문학은 1910년대의 형성기와 20년대의 전개과정을 거쳐 30년대엔 성숙기를 맞이한다.

도시가로변 건축물 외부색채의 현황에 관한 연구 : 제주시 서부해안도로를 중심으로 Focused on the Western Seashore Road in Jeju City

문석준,박철민 제주대학교 공과대학 첨단기술연구소 2003 尖端技術硏究所論文集 Vol.14 No.2

The purpose of this study is to provide practical guide for the situation of exterior color design in the urban street. The problems with exterior color of the buildings in Western Seashore Road as the subject did not form harmony between surrounding buildings and with natural environment of the region. And it was deficient in the recognition of color planning in a viewpoint of of organism. This study is survey and analysis of the street image which is made by building exterior color, through grasp color distribution of building dominant color. subdominant color and accent color. As a result, it is the value of this study to complement them and it is more desirable than the individual level to apply the results of this study in the public level through the systematic means of control.

超短波治療의 效率性에 關한 臨床檢討

文錫哉,羅相孝,金宇煥 圓光大學校 漢醫科大學 1984 圓光漢醫大論文集 Vol.- No.2

This study is investigated to examine how efficiently the ultra short wave-cure utensil would be helpful to acupuncture treatment. Through investigation, we abtained the following consequences in result of ultra short wave cure [with acupuncture treatment in the causes of 15 patients (44.12%)] to 34 cases of patients who had come receive treatment in Kwang Ju oriental medical Hospital for 2 months from July to August, 1984 ; 1) According to the proportion of males to females, the number of female patients [21 cases (61.76 %)], is more than that of male patients [13 cases (38.24 %)], and in age the ages between 10 and 29 os the highest in th rate. 2) In term of onset of disease, the cases of 10 days period formed 41.18 %(14 cases) of the total and over 2 years period were second 14 cases (29.41 %). 3) In the frequency of treatment, 10-20 times was 88.24 %(30 cases) of the total and in term, 20-40 days was necessary in treatment. 4) More of abjects were patients in motornervous system. 5) In spite of chronic patients in most objects, significant efficiency was abtained in 70.59 %(24 cases).

체홉의 심리주의 연구

문석우 조선대학교 인문학연구소 1997 外國文化硏究 Vol.20 No.2

At present research in human nature holds a great importance in contemporary literatures. This is because understanding of art reveals the realms of the human inner spirit within the intricate social inevitabilities. Anton Chekhov renovated his own creative principles, carrying on the literary traditions of 19th century Russian masters of psychological description, for example, Pushikin, Rermontov, Turgenev, and Tolstoy. Chekhov disclosed the individual inner spirit and psychological description through characters of his works by using of underlying cues, reservation, subjectivity of landscape, pause, details, and hints. This paper analyzes and supports his creative principles through his short stories and dramas, Uncle Vanya, Three Sisters, Bride, At Friend's Home and others. Contemporary prose writers, Shikshin, Abramov, Trifonov, Kazakov, Zalygin and others, have taken a subjective view of prose and have strengthened lyrical principles by widely using inner monologues which were developed abruptly from Chekhov's psychological principles. To conclude, Chekhov's psychological creative principles have helped to understand more easily the complicated human inner spirit in contemporary society and have provided the possibility of approaching nearer to it.

분산 자동차 시스템에서의 실시간 비주기 태스크 스케줄링

문석환 충북대학교 산업과학기술연구소 2022 산업과학기술연구 논문집 Vol.36 No.1

본문참고

러시아 고대문학의 "장엄한 역사주의" 문체 연구

文錫禹 조선대학교 외국문화연구소 1987 外國文化硏究 Vol.10 No.1