경연 대회를 통한 초ㆍ중고생의 창의력 신장 효과에 관한 연구

이희복,육근철,류해일,김현섭,김희수,박달원,유병환,김선효,김여상,서광수,변두원,서명석,배성효,박종석,심규철,이성희 공주대학교 과학교육연구소 2001 과학교육연구 Vol.32 No.1

미래 사회를 대비하기 위한 개인의 개성을 존중과 창의적인 능력을 지닌 인간을 양성을 목적으로 충청남도 지역의 초 ㆍ 중고등학생들을 대상으로 한 창의력 경연대회가 공주대학교 과학교육연구소에서 개최되었다. 충청남도 초 ㆍ중 ㆍ 고등학생들을 대상으로 실시한 창의력 경연대회는 창조적 아이디어를 내어 스스로 문제를 해결해 나갈 수 있는 교육 프로그램을 제공하는 좋은 기회였음이 확인되었으나, 일부의 팀에서만 참신하고 재미있는 아이디어들이 제안되었다. 여학생의 참가자 수가 상당히 증가하였으며, 대체적으로 입상권의 학생들의 상당 부분이 여학생이라는 것이 특이할만하다. 학년이 올라감에 따라서 창의적인 아이디어를 내는 양이나 질에 있어서 뒤떨어지는 것으로 분석되었으며, 토론 학습의 적응력이 미흡하고 발표력 및 청취력에 있어서도 떨어지는 것으로 나타났다. 따라서 중 ㆍ고등학교의 학교교육에서도 학생들에게 프로젝트형 탐구학습 프로그램의 적용은 물론 토론식 수습을 통한 학생들의 사고의 전환의 기회를 제공해야 할 것으로 사료된다. The creativity competition was held to foster the creativity of elementary and secondary school students in the Institute of Science Education, Kongju national University. It was found that the creativity competition effected on the improvement of inventing creative ideas and problem solving activities. But, only some competitors participated in semifinal and final contests, presented original and interesting ideas. More female students participated in competition than last year. More female participants were awarded a prize than males. Totally, participants were defective in discussion and communication, and presentation and listening ideas. Increasing grades correlated inversely with creativity and originality. There is need of inquiry project teaming programs and presenting opportunities of conversion of thinking by discussing instructions in school

프리미돈의 한국인에서의 생체이용율시험

권광일,윤민혁,윤희열,박희찬,권준택,심희옥,김동출 충남대학교 약학대학 의약품개발연구소 2004 藥學論文集 Vol.19 No.-

A reversed phase HPLC method was developed and validated for the determination of primidone in human plasma. Propylthiouracil was used as an internal standard. Calibration curves were linear in the concentration range of 10-120 ng/㎖. The coefficient of variation of the intra- and inter-day precision were below 15%. The coefficient of variation of the accuracy were below 15% in the concentration range investigated. A bioavailability study was performed using the validated HPLC method. Twenty four healthy human male volunteers were orally administered 20 mg of primidone. The pharmacokinetic parameters were calculated using WinNonlin. The mean values of AUC_(LAST) was 85.0±17.7 ㎍ hr/㎖, C_(max) was 4.22±1.04 ㎍/㎖, T_(max) was 1.85±1.13 hr, t_(1/2) was 17.7±2.4 hr. The pharmacokinetic parameters and the HPLC method can be used for the desigm of bioequivalence study of primidone.

저탁도시 PAC와 Ca-PAX의 입자제거 및 슬러지 탈수성 비교

심유섭,유명진,조희경,이상수,곽종운 대한상하수도학회 2002 상하수도학회지 Vol.16 No.4

This study was accomplished to evaluate the characteristics of particle removal and sludge dewatering and to find out the optimal condition of coagulation depending on the dosage of different coagulants (PAC, Ca-PAX) in low turbidity water. The experiments were carried out at a pilot plant of conventional rapid sand filtration system using artificial raw water. There was no large difference in the removal efficiencies of turbidity and total particle counts for both coagulants. However, Ca-PAX was required less than PAC to obtain the same efficiency of removal, and the initial head loss in a filter increased more fastly in case of PAC. The results on the evaluation of sludge from settling tank indicated that specific resistance of sludge was decreased inversely to the dose of both coagulant and specific resistance of Ca-PAX sludge was lower than that of PAC, therefore dewatering of sludge in case of Ca-PAX was better.

스피로노락톤의 한국인 지원자에서의 약물속도론적 연구

심희옥,이선영,지웅길,김동출 충남대학교 약학대학 의약품개발연구소 2005 藥學論文集 Vol.20 No.-

A reversed phase HPLC method was developed and validated for the determination of spironolactone in human plasma. Fenoprofen was used as an internal standard. Calibration curves were linear in the concentration range of 2.5~200 ng/㎖. The coefficient of variation of the intra- and inter-day precision were below 15%. The coefficient of variation of the accuracy were below 15% in the concentration range investigated. A bioavailability study was performed using the validated HPLC method. Eight healthy male volunteers were orally administered 100 ㎎ of spironolactone. The pharmacokinetic parameters were calculated using WinNonlin. The mean values of AUC_(12hr) was 158.9±69.9 ngㆍhr/㎖, C_(max) was 42.2±14.9 ng/㎖, T_(max)was 1.79±0.60 hr, t_(1/2) was 2.72±0.87 hr. The pharmacokinetic parameters and the HPLC method can be used for the design of bioequivalence study of spironolactone.

韓國 輸出企業의 인터넷을 이용한 사이버貿易 具現 및 成果에 관한 연구

심상렬,문희철 한국통상정보학회 2000 통상정보연구 Vol.2 No.2

인터넷의 급속한 보급 및 확산은 국제무역에 있어 일대 혁신을 초래하고 있으며, 특히 해외시장조사, 해외홍보 및 마케팅, 거래선 발굴, 신용조사, 거래협상 등 계약 체결 이전까지의 거대경로에 있어 시간과 공간의 제약이 없이 저렴하고 신속하게 글로벌 비즈니스를 수행할 수 있게 하고 있다. 본 연구에서는 한국 수출기업들이 어떠한 업무에 어느 정도나 인터넷을 활용하고 있는지, 실제로 어떠한 활용성과를 거두고 있는지 등을 설문조사에 의한 실증분석을 살펴 봄으로써 국내 수출기업들의 인터넷을 활용한 전자상거래, 즉 사이버무역 내지 전자무역의 활성화 및 국제경쟁력 제고 방안을 모색하고 있다.

低酸素馴化가 循環血液總量 及 血液蛋白質에 미치는 影響에 關한 實驗的硏究

沈鳳燮,趙圭輝 공군본부 의무감실 1956 항공의학 Vol.4 No.1

노인의료서비스정책의 발전방안에 관한 연구

심민수,정희선,심미연 원광대학교 대학원 2007 論文集 Vol.38 No.-

The population of the Aged in Korea is more rapidly growing, as compared with that of other countries, which raises serious intricacies in every walk of life, including politics, economy, society, and so forth. In particular, old-age medical service may be said to be one of the largest variables that produce a direct effect upon the good quality of old-age life. Furthermore, it functions as one of the most difficult impedi-ments in building an integration in society. The republic of Korea has made a great deal of efforts for old-age medical service but is now in an early stage. With this n view, this study puts its principal objective on groping for measures for the development of old-age medical service, and suggests some of them, as follows: First, from an environmental perspective, the Republic of Korea is greatly affected by its political influencing power, and so politics and economy need to be grow to a higher stage. And this study suggests changes in the overall age-group social structure and the eradication of a negative image of the aged, on a sociocultural side Second, it is recommended to boldly correct unreal or irrational laws and systems if any, on a legal system dimension. And this study suggests some strategies to establish old-age hospitals, to expand professional personnel, and to extend the range of medical allowances. Thirds, this study suggests measures to pay medical allowances for old-age health diagnoses for disease prevention is the national medical insurance system, to reduce the cost bearing in the use of high-priced medical equipments, to extend the application of administration of Oriental medicine and dental treatment in the old-age medical allowances. Fourth, this study suggests how to objectify the selection of subjects of the underprivileged, how to rationally calculate the amount of properties according to the standards of income, and how to reduce supporting obli-gators for beneficiaries of medical allowances for the underprivileged. Fifth, this study suggests the diversification and specialization of sanatoriums, the generation of subjects of home old-age welfare, and methods of rational fund-raising for long-term medical care. Sixth, this suggests the establishment of an old-age welfare police-making organization in the government, proper personnel allotment, the reestablishment of administrative functions among local governments, and the securement of officeholders in charge of social welfare. Finally, it is absolutely needed to augment the budget to expand the substrata of old-age medical services. In addition to it, to secure a budget on a proper scale for old-age medical services in consideration of the growing population of the aged.

HPLC를 이용한 농약코빈(thiophanate-methyl)의 측정법에 대한 연구

沈凞祥,金昌世 순천향대학교 1990 Journal of Soonchunhyang Medical Science Vol.13 No.1

가상현실 기법의 활용이 지식 성취도 향상에 미치는 효과 : 눈의 구조와 기능 내용을 중심으로 The Structure and Function of Eye

심규철,류수정,김현섭,김희수,박영철 한국과학교육학회 2003 한국과학교육학회지 Vol.23 No.1

The purpose of present study was to develop teaching-learning materials based virtual reality technology(VRT), and to examine the effect of it on the knowledge achievement of biology. Authoring tool of virtual reality(VR) was 3D Webmaster made in Superscape Ltd., United Kingdom. Educational materials was developed for the structure and function of eye of life field in the 10th science. It was learner-directed and interactive educational material using the Web-based and desktop VR. The result showed a meaningful improvement on the achievement. Using 3D VR shows the potential of available education media in the next generation as science teaching-aided material, which especially was efficient in the understanding and perception of abstract or difficult to direct experience learning contents.

우울장애 환자에서 자살 시도와 트립토판 수산화 효소(Tryptophan Hydroxylase) A218C 유전자 다형성과의 관련성

심세훈,황보영,권영준,정희연,이분희,김용구 대한신경정신의학회 2008 신경정신의학 Vol.47 No.2

Objectives : Several lines of evidence suggest the serotonergic dysfunction involved in the biological susceptibility of suicide. Tryptophan hydroxylase (TPH), the rate-limiting enzyme in the biosynthesis of serotonin, Plays a vital role in serotonin metabolism. In a case-control study, we investigated whether the TPH gene was a susceptible factor for suicidal behavior in depressive patients. Methods : The subjects were 218 depressed patients who attempted suicide and visited emergency rooms in multi-medical centers. One hundred thirty hospitalized non-suicidal depressed patients and the 161 normal controls were matched with the suicidal group. Individuals in all 3 groups were evaluated independently by a Structured Clinical Interview for the purpose of establishing a DSM-IV criteria diagnosis (SCID). The severity of depressive symptoms was evaluated using Hamilton depression rating scale (HDRS). Results : There was no significant difference in genotype distributions and allele frequencies of TPH intron 7 A218C polymorphisms among 3 groups. Furthermore, no significant difference in genotype counts and allele frequencies of the polymorphisms was found among lethal suicidal depressed patients, non-suicidal depressed patients and the normal controls. Conclusion : This study suggests that the A218C polymorphism of the TPH gene is unlikely to have a major effect on the susceptibility of suicidal behaviors in depressive patients.