비목별 분포 분석을 통한 공사비 투입 곡선 예측 모델

서장원,손보식,이현수 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2

Recently, feasibility study in Korean construction industry becomes important with the increasing development projects. Especially, economical efficiency study of feasibility study is an important step that decides feasibility, and accurate cash flow analysis is needed in this step. However, in Korean construction industry, research about this field is poor. In most construction company, they use total cost by informal calculation and cost distribution method using standard normal distribution, but this method has a low accuracy. In this study, we found weaknesses of existing methodology through literature review and case-study of 23 projects that carried by a large construction company of korea during recent 7 years. Also, we propose a forecasting model of cost flow curve using triangular distribution and investment curve classified by items of expenditure.

유전치의 polyethylene fiber-post를 이용한 심미수복에 관한 증례 보고

서영주,조태식,김효석,고승백,정현구,이난영 조선대학교 구강생물학연구소 2002 口腔生物學硏究 Vol.26 No.2

In clinical practice, restoration of primary incisors severely affected by caries continues to be a challenge. Not only are these teeth difficult to restore. but the behavior of the patient can affect treatment negatively. An acceptable restoration for maxillary anterior incisors should have matching material color, durability, adhesive cementation that is biocompatible with the pulp, easily and rapidly placed. This Paper describes two cases showing an alternative technique for the construction of completely destroyed upper incisors with polyethylene ribbons for retention and stability for the resin crowns.

Helicobacter pylori 양성인 소화성 궤양 및 위염 환자에서 Helicobacter pylori 제균에 대한 판토프라졸 포함 삼제 요법의 임상효과 및 내약성에 대한 연구

서영호,이완식,주영은,김현수,최성규,유종선,김행재,서순팔,김세종 최신의학사 2000 最新醫學 Vol.43 No.11-12

제통단이 퇴행성 슬관절염 환자의 삶의 질에 미치는 영향

서병관,류성룡,강중원,우현수,이상훈,이재동,최도영,김건식,이두익,이윤호 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

Objectives : to evaluate the effects of Jetongdan, the newly developed herbal medicine, on the quality of life in patients with osteoarthritis of knee Methods : Placebo-controlled, randomized clinical trial on the 80 patients with osteoarthritis of the knee was fulfilled. After enrollment, they took medication as they enrolled. And they were asked to answer the questionnaires (Korean Health Assessment Questionnaire (KHAQ), Lequesne's functional index (LF1), visual analogue scale (VAS)) and analysed with the erythrocyte sedimentation rate (ESR) at baseline, after 4 weeks and 8 weeks of medication. Results : Total KHAQ score, some categories of KHAQ like hygiene, activities were significantly improved after 8 weeks of medication. And the change of the KHAQ score was significantly correlated with the change of VAS. But LFI, VAS, ESR level was not significantly improved, and it was considered because of the short medication period and small size of study population. Conclusion : In conclusion, Jetongdan could improve the health-related quality of life in patients with osteoarthritis of knee. Further study in the large population, in long period were recommended.

뇌졸중 후 중추성 통증 환자에 대한 동서협진이 진통과 재활에 미치는 영향

이현종,김수영,이상훈,서동민,이두익,김건식,이재동,이윤호,양형인,박재경,최도영 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2003 東西醫學硏究所 論文集 Vol.2003 No.-

Purpose : In order to study the effectiveness of East-West pain treatment on central poststroke pain(CPSP), we evaluated its effect on alleviation of pain and rehabilitation of CPSP Patients who were treated with electroacupuncture and west pain treatment for four weeks. Methods : Twenty four patients diagnosed by their pain characteristics of central pain from stroke were treated with sympathetic nerve block, gabapentin, amitriptyline, and electroacupuncture for four weeks. Pain intensity through the visual analogue scale(VAS), and improvements of mobility and rehabilitation through the modified Barthel index(MBI) and Rankin scale(RS), respectively, before and after pain treatment were also assessed. Results : VAS pain scores were significantly improved from 7.7±1.7 to 4.4±2.0 with pain treatment(p<0.05). In accordance with improvement of pain scores, RS and MBI scores were also improved from 2.88±0.95 to 2.13± 1.01 and from 83.0± 16.9 to 94.7±9.5(p<0.05), respectively, with pain treatment(p<0.05). Conclusions : It was suggested that the active pain treatment was contributed to the rehabilitation of CPSP patients, resulting in improvement of quality of life of CPSP patients. Futhermore, East pain treatment in combination with West pain treatment may be useful modality to alleviate CPSP.

一般强度 圓形鋼管과 高强度 콘크리트가 合成된 短柱의 擧動特性

姜賢植,林書亨 진주산업대학교 2000 論文集 Vol.39 No.-

A composite structural system using concrete and steels, which is called "steel reinforced concrete" system has been used for buildings taller than 6-story. In these days Concrete Filled steel Tubular(CFT) members has become very popular and constructions are increasing. The results of axilly loaded circular stub columns is introduced in this paper. Sixteen specimen were tested to investigate the effect on the ultimate strength of inner concrete and diameter to thickness ratio. As a result of this study, we found that the circular hollow section members filled with high strength concrete showed the increasing rate from 1.03 to 1.14. The purpose of this study is to evaluate the characteristics of CFCT stub columns filled with high strength concrete and. suggest the basic data for the design of Concrete Filled Tubular structures.

W^(sh)/W^(sh) 마우스 고환에서 Protein Kinase C(PKC)와 c-kit의 발현 양상

곽현정,최병민,서기석,임정식,정헌택 大韓免疫學會 1996 大韓免疫學會誌 Vol.18 No.3

Protein kinase C (PKC) is a multigene family of at least nine serine/threonine kinases that are central to many signal transduction pathways. And the expression of PKC gene is strictly con-trolled by developmental stage. Mutation of the W (c kit) gene, which encodes a transmembrane tyrosine kinase receptor, affect the development and differentiation stem cells. Most homozygous W mutant mice are sterile, due to a lack of germ cells arising during embryonic development, but one of notable exception is W */Wh mice, which are fully fertile in both sexes. In order to elucidate the biological functions of PKC S and c-kit in the testes, we have examined the expression of PKC b mRNA and c-kit mRNA in While mouse testes by means of Northern blotting. North-em blot results was demonstrated that only PKC 8, 4, 8 mRNA can be detected in normal mouse testes. PKC, 8 mRNA was weakly expressed in 7 and 8-week-old mice and highly ex-pressed by 12 weeks. The PKC 8 mRNA and the c-kit mRNA was detectable in the testes of Whl Wh mouse. These results indicated that the function of the PKC a gene is necessary for the development and the W (c-kit) gene is important for the transmission of signal in testes.

골아세포 MC₃T₃-E₁의 증식과 기능에 Insulin Like Growth Factor Ⅰ, Ⅱ 및 부갑상선 호르몬이 미치는 영향

윤현구,정호연,양인명,김성운,김진우,김광원,김영설,최영길,서광식 대한내과학회 1992 대한내과학회지 Vol.42 No.1

MC₃T₃-E₁골아세포군을 이용하여 IGF-Ⅰ과 Ⅱ를 투여하고 DNA합성과 골아세포기능을 측정하기 위해 PTH에 대한 C-AMP반응정도, alkaline phosphatase 활성도를 측정하여 다음과 같은 결과를 얻었다. 1) IGF-Ⅰ과 Ⅱ는 모두 DNA합성이 어느 농도까지는 증식효과를 나타내지만 그 이후에는 억제되는 양상을 보였다. 2) PTH에 대한 골아세포의 C-AMP반응으로 증가되었지만 IGF-Ⅰ과 Ⅱ의 투여시 농도변화에 따른 의미있는 변화는 없었다. 3) 본 실험의 조건에서 alkaline phosphatase 활성도는 증가되지 않았다. 이상의 결과로 MC₃T₃-E₁ 골아세포에 IGF-Ⅰ과 Ⅱ는 세포의 증식을 자극하여 PTH는 C-AMP생성을 촉진하는 효과가 있었다. The effect of insulin-like growth factor (IGF) Ⅰ and Ⅱ on cloned MC₃T₃-E₁ cells that had osteoblastic activity was examined by [³H] thymidine incorporation into DNA, cyclic AMP responsiveness to parathyroid hormone (PTH), and alkaline phosphatase activity. IGF Ⅰ and Ⅱ stimulated the growth and proliferation of osteoblastic cells at 20ng/㎖ and 50ng/㎖, respectively. We next examined the effect of IGF-Ⅰ and Ⅱ on the expression of osteoblastic activity. Adenylate cyclase response of PTH to IGF-Ⅰ and Ⅱ-treated cells showed maximal stimulation at 10 and 50㎚PTH, respectively, but IGF Ⅰ and Ⅱ induced limited activity of osteoblastic function. In conclusion, IGF-Ⅰ and Ⅱ were potent stimulators to the growth of osteoblastic cells but did not have an immediate effect on expression of osteoblastic function in this experiment.

실리카흄을 사용한 충전강관용 초고강도 콘크리트에 관한 연구

임서형,강현식 진주산업대학교 2000 論文集 Vol.39 No.-

The purpose of this study is to investigate properties of the ultra high strength concrete using silica fume for concrete filled tubular. For this purpose, the properties of concrete are examined with varing water/binder ratio, binder content, maximum size of coarse aggregate, sand/aggregate ratio. From these test results, it is possible to manufacture the maximum compressive strength of 1008㎏/㎠ with binder content 560㎏/㎥, 21% water/binder ratio, 10% silica fume content. And it is possible to predict the 28day compressive strength from the 7day strength. The equation for prediction is suggested.

한국인의 각막에 관한 연구

강현식,김대년,김상연,강인산,박은규,서용원 대구보건대학 1999 대구보건대학 論文集 Vol.19 No.-

As the results of measurement of the radius of corneal curvature by keratometry for the right eye of 100 subjects, the steep meridian radius is 7.21㎜ to 8.27㎜ and flat meridian is 7.45㎜ to 8.65㎜, for the left eye the steep meridian radius is 7.30㎜ to 8.35㎜, and flat meridian is 7.45㎜ to 8.72㎜. The mean value of radius of corneal curvature is 7.8㎜ for night eye, 7.8㎜ for left eye. The results of measurement of P-value by topography, it is ranged from 0.45 to 0.91 for the night eye, 0.55 to 0.90 for the left eye, mean value is 0.756 for right eye, 0.735 for left eye respectively. That means the corneal shape is ellipses. The corneal thickness is measured 0.69㎜ 10°degree to the nasal, 0.76㎜ 20°degree to the nasal, 0.66㎜ 10°degree to the temporal, 0.72㎜ 20° degree to the temporal from the visual axis and 0.60㎜ at the central position. The horizontal size of corneal is 11.34㎜ for the night eye, 11.373㎜ for left eye. Those data can be used for contact lens design and fitting.