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      • SCOPUSKCI등재

        악성 림프종 환자에서 발생한 다형홍반

        여운철,조광현,이유신,허대석,이승철 ( Un Cheol Yeo,Kwang Hyun Cho,Yoo Shin Lee,Dae Seog Heo,Seung Chul Lee ) 대한피부과학회 1990 대한피부과학회지 Vol.28 No.5

        A Case of Erythema Multiforme A ssociated with Malignant Lymphoma Un Cheol Yeo, M.D., Kwang Hyun Cho, M.D., Yoo Shin Lee, M.D., Dae Seog Heo*, M.D., Seoung Chul Lee**, M.D Department of Dermatology and Internal Medicine*, College of Medicine, Seoul National University, Seoul, Korea, Department of Dermatology**, College of Medicine, Inha University, Kyung Gi Do, Korea We report a case of erythema multiforme associated with malignant lymphoma. Fifty-six-year-old male patient visited our clinic complaining generalized skin lesions which were compatible with erythema multiforme clinically and histopathologically. The skin lesions were treatment-resistant, recurrent and persistent for 3 years. In consideration of old age, atypical features of erythema multiforme and no other demonstrable etiology of erythema multiforme, we studied for internal malignancy. Malignant lymphoma at the duodenum was revealed by UGI series, abdominal CT, and endoscopic biopsy. After chemotherapy, the tumor mass and active skin lesions were cleared simultaneously. Erythema multiforme may be regarded as one of the paraneoplastic syndromes.

      • KCI등재

        구조물의 진동 완화를 위한 스마트 감쇠 시스템의 설계 : Part 1. 단일 리야프노프 제어 알고리즘의 전개와 수치적 검증 Part 1. Application of Unified Lyapunov Algorithm and its Numerical Verification

        허광희,이규,윤현도 대한건축학회 2005 大韓建築學會論文集 : 構造系 Vol.21 No.2

        This paper presents a new algorithm which is applicable in designing a smart damping system for vibration mitigation. The algorithm, which is extended into a unified system from Lyapunov stability theory, enables us to decrease the Quantization errors by its increased stability. The validity of this design method was proved in the numerical simulation on a control model of three-storied building structure. Smart damper was used for MR(magnetorheological fluid) damper in the numerical model, and its control effectiveness was evaluated. In order to make a more accurate control model numerical1y, we updated the model on the basis of the analysis of dynamic characteristics of structure and of the numerical analysis of a lumped mass model, and then adopted a state space model redefined by structural property matrix. Using this improved control model, control effect on structures which were under the influence of each different earthquake magnitude was analyzed with various performance index, and thus the algorithm presented here is proved to be valid.

      • 방광 소세포암:1예 보고

        허정남,김용수,조온구,고병희,임현철,함창곡 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.2

        Small cell carcinoma(also known as oat cell carcinoma) of the urinary bladder is an extremely rare malignancy and is derived from neuroendocrine stem cells. It is usually biologically aggressive tumor with early vascular and muscle invasion, so it has poor prognosis. Radiological findings of small cell carcinoma are similar to other malignancies of urinary bladder, therefore it is impossible to distinguish small cell carcinoma from other malignancies. Pathologic study is an only useful method for differential diagnosis of bladder tumor. We report here the case of 74th years old woman presented with painless gross hematuria.

      • 수술 전 진단된 충수돌기 점액류종 1례

        허광식,손현화,김동규,박찬국,김만우,김정용,기근홍 조선대학교 부설 의학연구소 2000 The Medical Journal of Chosun University Vol.25 No.1

        Primary unruptured appendiceal mucocele is a rare disease. It is very difficult to diagnose preoperatively because of the rarity of classical symptoms and low incidence. Usually it is discovered incidentally during abdominal ultrasonography(US), computed tomography(CT), or appendectomy for acute appendicitis. If untreated, one type of mucoceles may rupture producing a potentially fatal entity known as pseudomyxoma peritonei, therefore preoperative diagnosis is very important. With the advent of colonoscopy, abdominal US and CT, it has been possible to preoperatively diagnose mucocele of appendix. We experienced a case of appendiceal mucocele in a 60 year-old woman who had symptoms of lower abdominal discomfort and right lower quadrant abdominal pain, and it was diagnosed preoperatively by colonoscopy, abdominal US and CT. So we present this case with review of literature.

      • 아파트 외부공간에서 아동의 장소형성에 관한 연구 : A Case Study of Apartment Housing

        허현태,이종현,민병호 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(계획계)

        Children's place making was analyzed in neighborhood environments of an apartment site. Open-ended interviews of 34 children, behavior observations of children in neighborhood spaces, and behavior mapping of the places were performed to investigate what were the neighborhood places important to children's everyday life, how they emerged, and what meanings these places had to the children. Ten different places were mentioned as important setting in their neighborhood. These places coincided the locations where behavior observations showed the children were engaged in neighborhood activities most often. This indicates that place and activity correlate. These places were important because they provided settings for social contacts/interactions (including meeting friends), recurrent habitualized activities (including plays), and memories of past events. Important also were physical conditions that helped the children have these experiences. Overall, the analysis indicates that activity is the most important aspect of the place experience, along with friends and play colleagues to share the activities, memories of past events associated with the places, and physical properties of the places supporting the activity experience.

      • 공공스포츠시설의 민영화에 관한 연구

        허현미 경인여자대학 2003 경인논집 Vol.- No.10

        this study was attempted to examine how much our public sports facilities have been operated, meeting their purposes and suggest a future improvement plan centered on the privatization by literature review and analysis on practical data of our national public sports facilities. Unless it is clearly reestablished whether the government is to convert the functions of public sports facilities into those of profit facilities or to leave public sports facilities as they are, an attempt to privatize them at the level of a local autonomous body must invite danger of just making the identity of the functions of public sports facilities ambiguous. Focused on such point, a privatization plan was suggested in two aspects in this study - public service offering and profit creation.

      • 석면함유 슬레이트 지붕 물받이 퇴적물 중 석면 섬유 함유율

        임지현,한솔민,김현석,신유민,박시은,허정윤,김민영,장봉기 순천향대학교 기초과학연구소 2022 순천향자연과학연구 논문집 Vol.28 No.1,2

        This study attempted to determine the degree of asbestos release from the aging slate roof by comparing the asbestos content in the slate roof rain gutter with a colored steel plate (tin plate) over the slate roof. Four slate roof houses located in Haengmok-ri, Asan-si, Chungcheongnam-do, and one house constructed with a colored steel plate on the slate roof were selected to collect the sediment of the roof rain gutter. The asbestos fiber content was calculated by a point counting method using a polarization microscope after pretreatment with conversion treatment and hydrochloric acid treatment. The average asbestos content of the four slate roof rain gutter were 1.89%. However, asbestos was not detected in the Slate covering roof rain gutter, which were constructed on the slate roof. Asbestos fiber content was the highest at 2.89% in the slate roof rain gutter installed in 1976, followed by 2.44% in 1953. From the above results, it is necessary to minimize secondary damage as asbestos fibers released from slate roof houses to the surrounding atmosphere or leaked from slate roofs as rainwater may cause soil pollution and seriously affect residents' health. Although covering with colored steel plates (tin plates) has been shown to prevent the leakage of asbestos fibers to some extent, it is believed that a policy alternative to remove the slate roof as soon as possible is needed to solve the fundamental problem.

      • KCI등재

        백서의 하악골 전방 재위치 시 하악과두 조직에서의 nitric oxide synthases 발현 양상

        김현숙,김호영,허성수,강경화,김상철 대한치과교정학회 2010 대한치과교정학회지 Vol.40 No.4

        Objective: The aim of this study was to identify the expression of nitric oxide synthases (NOS) in the mandibular condyle during mandible advancement by functional appliance and to correlate it with the histologic changes and bone remodeling. Methods: Twenty-four female, 35-day-old Sprague-Dawley rats were randomly divided into 3 experimental groups. In all experimental groups, the mandibles of the rats were kept in a continuous forward position with a fixed bite jumping appliance. The rats were sacrificed on the 3rd, 14th, and 30th days of experiment. More than 2 rats in each group were used for staining. Results: There were no remarkable histologic changes and NOS expression differences in the control group. The most prominent histologic changes occurred in the 14th day experimental group. NOS decreased in the 30th day experimental group. There was increased expression of NOS₂ and NOS₃ in all experimental groups, comparative to the control group. In all the experimental groups and control group, the expression of NOS₂ was greater than that of NOS₃. Conclusions: It is postulated that NOS₂ and NOS₃ in the mandibular condyle might play an important role in bone remodelling of the mandibular condyle. 성장기 아동의 하악과두 조직에서의 골개조 과정은 연골세포, 조골세포, 파골세포가 연관되며 nitric oxide synthase (NOS)가 중요한 매개자의 하나로 작용할 것으로 생각되나 기능성 악정형술을 이용해 하악골을 전방유도시켰을 때 하악과두에서의 골개조와 NOS 의 발현에 대해서는 아직 자세히 연구되어 있지 않다. 본 연구는 하악골을 기능적으로 전방위치시켰을 때 하악과두 조직의 조직학적 변화양상에 대해 살펴보고 NOS 의 발현 정도를 조사하여 상관관계를 알아보고자 하였다 . 35일령의 24마리의 Sprague-Dawley 백서를 3군으로 나누었고 각 군에 있어서 5 마리는 실험군으로 3마리는 대조군으로 나누었다. 실험군은 하악골 전방유도장치를 24시간 장착한 후 3, 14, 30 일에 희생하였으며 시상면에 평행하게 절단하였고 NOS₂와 NOS₃의 조직면역염색을 통해 다음과 같은 결과를 얻었다. 대조군 간에는 조직학적인 변화와 NOS 의 발현 번화가 뚜렷이 관잘되지는 않았으며 실험기간에 따른 조직학적 변화는 실험 14일 군에서 가장 많은 신생골 형성과 조골세포 활성을 보였으며, 실험 30 일 군에서는 감소하는 양상으로 나타났다. 또한 모든 실험군에서 대조군에 비해 NOS₂와 NOS₃의 발현이 많이 나타났으며 실험기간에 따른 비교 시 NOS₂와 NOS₃의 발현은 실험 14 일 군에서 가장 많이 나타났으며 실힘 30 일 군에서는 감소하는 양상으로 나타났다. 전체 실험군과 대조군에서 NOS₂의 발현은 NOS₃의 발현보다 많이 나타났고 NOS₂는 실험군 과두의 비대연골, 연골하골에서 주로 발현되었다. NOS₃는 실험군 과두의 골수와 모세혈관에서 주로 발현되었다. 따라서 하악과두 내의 NOS₂와 발현조절이 하악과두 조직의 골개조에 관여함을 시사한다.

      • KCI등재

        파노라마방사선사진 지수와 임플란트 실패와의 관계에 관한 연구

        조현정,이원진,허민석,안창현,이진구,이삼선,최순철 大韓口腔顎顔面 放射線學會 2004 Imaging Science in Dentistry Vol.34 No.1

        Purpose : Several panoramic indices have been suggested to assess bone quality from the morphology and width of mandibular cortex on panoramic radiography. The purpose of this study was to compare dental implant failure group with control group in panoramic mandibular index (PMI), mandibular cortical index (MCI), and gonion index (GI) and to determine the effect of these panoramic indices on dental implant failure. Materials and Methods : A case-control study was designed. Test group (n = 42) consisted of the patients who had their implants extracted because of peri-implantitis. Control group (n = 139) consisted of the patients who retained their implants over one year without any pathologic changes and had been followed up periodically. They had dental implants installed in their mandibles without bone augmentation surgery from 1991 to 2001. The following measures were collected for each patients: 1) PMI, MCI, and GI were measured twice at one-week interval on preoperative panoramic views; and 2) age, sex, implant length, implant type, installed location, occluding dentition state, and complication were investigated from the chart record. Results : The PMI showed moderate level of repeatability. The intra-observer agreement of MCI and GI were good. There was statistically significant difference in PMI between two groups. There were significant different patterns of distribution of MCI and GI between two groups. Among the panoramic indices, PMI and MCI showed significant correlation with dental implant failure. Conclusion : Panoramic indices can be used as reference data in estimating bone quality of edentulous patients who are to have implants installed in their mandibles.

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