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최혁재(Choi, Hyukjae),장희순(Jang, Heesoon) 한국주거환경학회 2021 주거환경(한국주거환경학회논문집) Vol.19 No.4
이 연구는 부동산간접투자에 투자하는 위험과 기대수익 선호도가 다른 투자자의 투자 특성과 그에 부합하는 수익증권 및 주식발행 조건을 파악하는 데 초점을 맞추고, 투자자가 취하고자 하는 위험 정도를 파악해 투자자가 요구하는 투자 유형에 대하여 확인하였다. 간접부동산투자는 기업과 개인이 부동산투자회사(리츠)와 부동산집단투자단체(펀드)를 이용해 임대수익이나 매매차익을 받는 투자 방식으로. 부동산펀드는 소액펀드를 활용해 임대수익이나 배당수익을 누리는 일종의 도관체가 되고, 부동산펀드는 대출자금, 임대자금, 개발자금 등으로 나뉜다. 이를 위해 투자자별 부동산펀드와 리츠의 특성 비교분석에 적합한 교차분석을 이용하여 통계적으로 검증하고, 부동산 간접투자상품을 통해 부동산시장 상황에 적합하면서도 안정적으로 부동산개발에 필요한 자금을 지속적, 반복적으로 공급하기 위하여는 부동산펀드 및 리츠 투자자들의 특성을 파악하여 이들의 요구에 부응하는 증권의 발행과 이러한 금융상품에 투자하는 투자자 특성을 파악하는 것이다. Indirect real estate investment has an investment method in which companies and individuals receive rental income or gains from sale using real estate investment companies (Ritz) and real estate collective investment organizations (funds). REITs serve as a kind of conduit for investing in real estate products using small funds to enjoy rental income or dividend income, and real estate funds are divided into loan funds, rental funds, and development funds.The study focused on identifying beneficiary securities and stock issuance conditions that meet investor characteristics by investors with different risk-expected return preferences, and attempted to prepare protection policies required by investors by identifying the degree of risk they want to take. To this end, it was statistically verified using cross-analysis suitable for comparative analysis of the characteristics of real estate funds and REITs by investor.The purpose of the study is to identify investors demands for securities issued by real estate funds and REITs to protect the people indirectly participating in the real estate market through the real estate indirect investment market and develop the national economy.
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( Sajita Shah ),( Chaemin Lee ),( Hyukjae Choi ),( Jaya Gautam ),( Hyeonjin Jang ),( Geum Jin Kim ),( Yu Jeong Lee ),( Chhabi Lal Chaudhary ),( Sang Won Park ),( Tae Gyu Nam ),( Jung Ae Kim ),( Byeong 영남대학교 약품개발연구소 2016 영남대학교 약품개발연구소 연구업적집 Vol.26 No.-
Angiogenesis plays important roles in tumor growth and metastasis. Sunitinib (sutent®) is an antitumor agent targeting receptor tyrosme kmases which are Involved in angiogenesis as well as cancer cell growth and survival. Using the pyridin-3-01 scaffold. which was previously reported as an excellent antioxidant and antiangiogenic platform, we have synthesized sunitinb mimics 6 by hybridizing bicyclic pyridlnol4 as a key scaffold and pyrrole-2-carbaidehydes 7 as side chains, Cytotoxicity assays showed that compounds: 6 have comparable to better anticancer activity than sunltll1lb against five different cancer cell lines. In addition. compounds 6 showed even lower levels of cytotoxicity against normal cells. resulting in up to 26-fold better safety Windows, than sunitinib, Signaling pathway-associated transcription factor reporter assay and western blot analyses revealed that apoptosis induction In MDA-MB-231 human breast cancer cells by 6F is mall1ly mediated through the pS3 increase and down-regulation of phospho-signal transdu-cer and activator of transcription 3 (STAT3) and its target gene products, cyclin D, Bcl-2. and survivin. The data strongly suggest that our hybrid compounds can provide a novel anticancer scaffold with Improved and safer cytotoxicity profiles than sunitinib.
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A Scalable and Energy-Efficient Context Monitoring Framework for Mobile Personal Sensor Networks
Seungwoo Kang,Jinwon Lee,Hyukjae Jang,Youngki Lee,Souneil Park,Junehwa Song IEEE 2010 IEEE transactions on mobile computing Vol.9 No.5
<P>The key feature of many emerging pervasive computing applications is to proactively provide services to mobile individuals. One major challenge in providing users with proactive services lies in continuously monitoring users' context based on numerous sensors in their PAN/BAN environments. The context monitoring in such environments imposes heavy workloads on mobile devices and sensor nodes with limited computing and battery power. We present SeeMon, a scalable and energy-efficient context monitoring framework for sensor-rich, resource-limited mobile environments. Running on a personal mobile device, SeeMon effectively performs context monitoring involving numerous sensors and applications. On top of SeeMon, multiple applications on the mobile device can proactively understand users' contexts and react appropriately. This paper proposes a novel context monitoring approach that provides efficient processing and sensor control mechanisms. We implement and test a prototype system on two mobile devices: a UMPC and a wearable device with a diverse set of sensors. Example applications are also developed based on the implemented system. Experimental results show that SeeMon achieves a high level of scalability and energy efficiency.</P>
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Chrysin attenuates atopic dermatitis by suppressing inflammation of keratinocytes
Choi, Jin Kyeong,Jang, Yong Hyun,Lee, Soyoung,Lee, Sang-Rae,Choi, Young-Ae,Jin, Meiling,Choi, Jung Ho,Park, Jee Hun,Park, Pil-Hoon,Choi, Hyukjae,Kwon, Taeg Kyu,Khang, Dongwoo,Kim, Sang-Hyun Elsevier 2017 Food and chemical toxicology Vol.110 No.-
<P><B>Abstract</B></P> <P>We previously reported the inhibitory effect of chrysin, a natural flavonoid plentifully contained in propolis, vegetables and fruits, on the mast cell-mediated allergic reaction. In this study, we evaluated the effect of chrysin on atopic dermatitis (AD) and defined underlying mechanisms of action. We used an AD model in BALB/c mice by the repeated local exposure of 2,4-dinitrochlorobenzene (DNCB) and house dust mite (<I>Dermatophagoides farinae</I> extract, DFE) to the ears. Repeated alternative treatment of DNCB/DFE caused AD-like skin lesions. Oral administration of chrysin diminished AD symptoms such as ear thickness and histopathological analysis, in addition to serum IgE and IgG2a levels. Chrysin decreased infiltration of mast cells, and reduced serum histamine level. Chrysin also suppressed AD by inhibiting the inflammatory responses of Th1, Th2, and Th17 cells in mouse lymph node and ear. Interestingly, chrysin significantly inhibited the production of cytokines, Th2 chemokines, CCL17 and CCL22 by the down-regulation of p38 MAPK, NF-κB, and STAT1 in tumor necrosis factor (TNF)-α/interferon (IFN)-γ-stimulated human keratinocytes (HaCaT). Chrysin also inhibited TNF-α/IFN-γ-stimulated IL-33 expression in HaCaT cells and mouse primary keratinocytes. Taken together, the results indicate that chrysin suppressed AD symptoms, suggesting that chrysin might be a candidate for the treatment of AD and skin allergic diseases.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Chrysin suppresses AD symptoms by inhibiting T helper cell immune reaction. </LI> <LI> Chrysin downregulates CCL17 and CCL22 expression via p38 MAPK, STAT1, and NF-κB in human keratinocytes. </LI> <LI> Chrysin and tacrolimus have overlapping effects in inhibiting AD immune responses. </LI> <LI> Chrysin might be a candidate for the treatment of skin allergic diseases. </LI> </UL> </P>
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