방사성 폐기물 시멘트 고화체로 부터의 ?? 및 ?? 용출특성 연구

황선태,이경주,최길웅,박헌휘,김환영 대한방사선 방어학회 1985 방사선방어학회지 Vol.10 No.2

방사성폐기물 처리, 처분의 안정성 평가를 위하여 방사성 고화체에서 용출되는 137Cs과 90Sr의 방사능 용출율과 누적용출분율을 계측·분석하여 시멘트를 사용한 방사성 고화체에서 Cs+과 Sr++의 용출특성을 조사하였다. 모의방사성 폐액의 몰농도, 시멘트의 종류, 첨가물질 및 붕산농도 등을 변화시키면서 sodium silicate법과 중화법으로 원주형 시멘트 고화제를 제작하였다. 여기에서 가압경수로형 원자력 발전소의 모의 농축폐액의 시멘트 고화체로부터 용출연구는 IAEA의 추천방법에 따라서 수행되었다. 실험결과는 대부분 이미 보고된 연구자료들과 잘 일치하고 있으나 수밀성 시멘트 고화체에서는 상당히 높은 방사능 용출율을 보여주고 있음으로써 방사성 폐기를 고화체에 그 사용이 적합하지 않음을 알게 된다. For the safety assessment of radwaste treatment and disposal, the leaching characteristics of Cs++ and Sr++ from the cement-solidified radwastes was investigated by means of the survey and analysis of the activity leach rate and cumulative leach fraction of 137Cs and 90Sr leaching from solidified radwastes. The cylindrical cement-solidified samples were made by the sodium silicate method and neutralization method changing the mole density of simulated liquid radwaste, type of cement, adding material and concentration of boric acid. The leaching study was carried out by the method using simulated PWR concentrated liquid radwaste solidified in cement that had been processed following the recommendations of IAEA. All the experimental results are in well accordance with the research data reported previously, but the watertight cement-solidified radwastes show rather high leach rate of radioactivity. It is learned, therefore, that the watertight cement is not adequate as the material for the solidified radwastes.

二面交雜에 의한 무(Raphanus sativus l.)의 收量 形質들에 대한 量的遺傳 分析

황주광,전병문,조대환 충북대학교 농업과학기술연구소 2001 農業科學硏究 Vol.18 No.-

Eight parents and a set of 28 diallel crosses were employed to investigate heterosis, combining ability and inheritance of yield characters in radish(Raphanus sativus L.). Using model 1 of Griffing's method 2, heterosis and combining abilities of above characters were estimated. With Jinks and Hayman's method, genetic variance component analysis were performed. The results obtained are summarized as follows. 1.Heterosis was highest for root weight(156.0%). Characters such as leaf weight (55.5%), root length(45.9%), root diameter of middle portion(39.2%), root diameter of lower portion(37.3%) and root diameter of upper portion(32.3%) showed positive heterosis, while T/R ratio(-41.9%) showed negative heterosis. 2.In the analysis of combining ability, mean squares of GCA and SCA were highly significant for the all characters investigated, except leaf length character. 3.The significant positive GCA effects for root length, root weight, number of leaves and root shape index were shown in Tokinashi and Minowase. Yonghyeon and Jungkukcheongpi showed the significant positive GCA effects for root diameter, root weight and leaf length. However, Jinjudaepyeong and Wulsanjaerae showed a negative GCA effect for root length and root weight and, especially Taimayhua showed a negative GCA effect for all characters investigated. 4.The combinations of Tokinashi x Taimayhua, Tokinashi x Wulsanjaerae and Jinjudaepyeong x Minowase indicated the significant positive SCA effects for root length, root diameter and leaf weight. 5.In the degree of dominance, root length, root diameter, T/R ratio, number of leaves and root shape index demonstrated partial dominance, while leaf length showed overdominance. 6.Dominance effects of genes were greater than additive ones for root length, root diameter and leaf weight. Number of leaves, T/R ratio and root shape index expressed larger additive effects. But root weight and leaf length showed overdominance. 7.Heritabilities in broad sense(h2B) were very high for all characters investigated. Heritabilities in narrow sense (h2N) were highs for root length, number of leaves and root shape index, but low for leaf length.

Fluoroacetate(Platol)중독 증상 연구 : 자살기도자를 중심으로

한창환,황주연,김경식,안석철 大韓神經精神醫學會 1984 신경정신의학 Vol.23 No.1

This study was designed to evaluate the clinical problems of fluoroacetate intoxication. The total number of the fluoroacetate intoxication patients who came to the emergency room of Han Gang Sacred Heart Hospital from Jan. 1, 1983 to Aug. 31, 1983 were 96 cases. Among them, 41 attempters who were consulted to the psychiatrist were evaluated and observed in detail. The following results were obtained. 1. The rodenticide poisoning accounts for 37.2% of all toxic substance intoxication(total 266 cases) at Han Gang Sacred Heart Hospital from Jan. 1983 to Aug. 1983. Among them, 96 cases(36.1%) of fluorcacetate intoxication were observed. 2. Female was affected 2.4 times more frequently than male. 35.5% of total cases belonged to age group 21∼30years, when incidence was most prevalent 3. As the route of drug obtainment, supplement were commonest(63.3%), purchase in 29.4%. 4. CNS disturbances such as drowsiness, stupor, semicoma and irritability were observed in 75.6% of the cases. Speech disturbances such as dysarthria, childish speech was observed in 9.8%of the cases. Convulsion(29.3%), tremor(12.2%) spasm and twitching(4.9%) were also frequently observed. Tachycardia was found in 43.8% of the cases and other frequent symptoms were nausea and vomiting(53.7%), abdominal pain(34.2%), mild or high fever(26.8%). Lower calcium(below 9mg) was found in 29.3% of the cases and lower potassium(below 3.5mEq) was found in 22.0% of the cases. EKG findings revealed QT prolongation(22.0%), ST-T change(22.0%) and u-wave, RBBB, and PVC(14.6%). 5. 92 cases(95.8%) recovered without sequelae and 4 cases(4.2%) expired.

超軟弱 粘土의 壓密特性 硏究

李揆丸,李松,黃圭鎬,金周豪 서울市立大學校 1994 論文集 Vol.28 No.-

In recent years, the projects dealing with the marine clay have raising tendency. For example, the dredged clay can be used directly as the reclamation fill material. In this case, it is important to understand the consolidation characteristics for settlement analysis. Using conventional testing procedure, the determination of the consolidation characteris tics of cohesive soils requires consolidation time. the constant rate of strain consolidation test has been proposed as a method to reduce consolidation test time. The information used to the characteristics of settlement has been obtained using a standard oedometer test, but standard oedometer test may not be applicable to very soft soils with high water content because of limations both in theory and in testing techniques. A new constant rate of strain consolidation testing technique for very soft soils with water content of 200 to 500 % is proposed as an alternative of conventioinal oedometer test. This paper presents several benifts on the constant rate of strain consolidation test. To find the consolidation characteristics of the dredged soft clay constant-rate-of-strain consolidation testing method is used In this paper constant rate of strain consolidation test are compared with standard oedometer test for applicablity of constant rate of strain consolidation test It is concluded that the consolidation constants of very soft clays can be accurately determined from the constant rate of strain tests,also is suitable test of derdged clays as this test is applicable to regimes of the low stress level and high stress level

광양만 유역 퇴적토 중의 다환방향족탄화수소류

정흥호,정호승,김은영,조환익,황주찬,최상원 한국환경과학회 2004 한국환경과학회지 Vol.13 No.6

Polycyclic aromatic hydrocarbons(PAHs) in sediments of Kwangyang bay on Korea, have been investigated by gas chromatography-mass spectrometery (GC/MS). The average content of total PAHs in all samples was 2,211ppb, and the range was from 36 to 22,699pph. The higher concentrations were found in sediment sampled near Kwangyang iron processing plant, Taeindo. The resulting distributions of PAHs according to the number of aromatic ring and molecular ratios of specific aromatic compounds (phenanthrene, anthracene, fluoranthene and pyrene) have been discussed in terms of sample location, origin of the organic matter. Four, five and six rings of PAHs were mainly found near to Kwangyang iron processing plant, and three and four rings near to Yeosu chemical kombinat. This result typically indicated the local characteristics, depending on the origin of PAHs.

광양만으로 유입하는 하천하구에서의 이화학적 특성 : 우수기 직후 유입하천에 따른 영향 effect of inputting rivers after rainy season in summer

김은영,정흥호,정호승,조환익,황주찬,최상원 한국환경과학회 2004 한국환경과학회지 Vol.13 No.9

Physicochemical characteristics of Kwangyang Bay, have been investigated on the effects of inputting rivers just after rainy season in summer 2003. The results ranged from 4.96~8.01 mg/L for DO, 1.16~3.09 mg/L for COD, 7.21~67.71 μM for DIN and 0.12~121.84 μM for phosphate. The COD of Yeosu Area was 1.19~3.09 mg/L, Kwangyang Area was 1.23 ~ 2.76 mg/L. The COD of Wallae cheon in Yeosu Area was 3.09 mg/L and Donghoan in Kwangyang Area was 2.76 mg/L. The reason of high COD might be industrial sewage of organic chemical plants and iron foundry. DIN of Yeosu Area and Kwangyang Area were 7.21--63.43 μM and 8.43 67.71 μM respectively. The average phosphate of Yeosu Area was 23.65 μM. The source of phosphate might be industrial sewages of fertilizer plant and phosphate gypsum stocked with high amounts. The metal concentrations were measured in the range of 1.01~175.10 ㎍/L for Cu, 0.13~1.78 ㎍/L for Cd, 1.13~5.21 ㎍/L for Pb, 1.58~13.57 ㎍/L for Cr and 1.07~20.68 ㎍/L for As. The average Cu concentration was 78.99 ㎍/L in Kwangyang Area. The source of Cu might be industrial sewage of iron foundry. The average Cr concentration of Yeosu Area was 9.07 ㎍/L. That is 2 times higher than Kwangyang Bay 5.74 gg/L, because of sewage of chemical plants.

Sulforaphene Attenuates Cutibacterium acnes -Induced Inflammation

Hwang Hwan Ju,김종은,이기원 한국미생물·생명공학회 2022 Journal of microbiology and biotechnology Vol.32 No.11

Acne is a chronic inflammatory disease of the sebaceous gland attached to the hair follicles. Cutibacterium acnes is a major cause of inflammation caused by acne. It is well known that C. acnes secretes a lipolytic enzyme to break down lipids in sebum, and free fatty acids produced at this time accelerate the inflammatory reaction. There are several drugs used to treat acne; however, each one has various side effects. According to previous studies, sulforaphene (SFEN) has several functions associated with lipid metabolism, brain function, and antibacterial and anti-inflammatory activities. In this study, we examined the effects of SFEN on bacterial growth and inflammatory cytokine production induced by C. acnes. The results revealed that SFEN reduced the growth of C. acnes and inhibited proinflammatory cytokines in C. acnes-treated HaCaT keratinocytes through inhibiting NF-κB-related pathways. In addition, SFEN regulated the expression level of IL-1α, a representative pro-inflammatory cytokine expressed in co-cultured HaCaT keratinocytes and THP-1 monocytes induced by C. acnes. In conclusion, SFEN showed antibacterial activity against C. acnes and controlled the inflammatory response on keratinocytes and monocytes. This finding means that SFEN has potential as both a cosmetic material for acne prevention and a pharmaceutical material for acne treatment.

Development Analysis Methods Using Macroporous Diatomaceous Earth Column for Organochlorine Pesticides in liquorice Root

Ju-Hee Lee,Kab-Sik Shin,Young-Hwan Jeon,Jeong-In Hwang,Hyo-Young Kim,Ju-Young Park,Ji-Sang Hwang,Rack-Seon Seong,Jang-Eok Kim 한국농약과학회 2010 한국농약과학회 학술발표대회 논문집 Vol.2010 No.4

Alteration in Phenolic Compounds and Antioxidant Activities of Aronia melanocarpa Ethanol Extracts following Fermentation Using Different Strains of Leuconostoc mesenteroides to Develop Natural Antibiotic Alternative

Hwang, Joo Hwan,Kang, Ju Hui,Lee, Ki Hwan,Lee, Jae Hoon,Lee, Sang Moo,Kim, Nam Hyung,Kim, Joo Young,Kim, Eun Joong 한국유기농업학회 2014 韓國有機農業學會誌 Vol.22 No.4

Antioxidant activity is important for reducing oxidative stress that causes various metabolic disorders. Metabolic disorders are highly related to loss of productivity in livestock. Therefore, development of effective antioxidant compounds originating from plants is important for organic agriculture. Phenolic compounds in edible plants are regarded as major components relevant to antioxidant activity. The present study investigated the changes in antioxidant activity and phenolic compound profiles of Aronia (Aronia meloncarpa) by fermentation using different strains of Leuconostoc mesenteroides. A total of 5 strains of L. mesenteroides were used as starter cultures and their β-glucosidase activities were measured. A total of 6 experiment runs were prepared, one for control (uninoculated) and the others (inoculated) for treatments. For biological activity, antioxidant and antibacterial activities were measured. For phenolic compound profiling, TLC and HPLC analysis were performed. The strains of KACC12313 and KACC12315 showed greater enzyme activity than others. Treatment with KCCM35046 showed strong and broad antibacterial activity against to Listeria monocytogenes. Treatments with KCCM35046 and KACC12315 showed the highest total polyphenol content. The highest antioxidant activity was found in KACC12315 treatment. No remarkable alteration was found in thin layer chromatography (TLC) analysis. In phenolic compound profiling analysis, KCCM35046 showed notable alteration in compound area ratio compared to others and also showed the highest caffeic acid content. In chlorogenic acid, treatments with KCCM35046 and KACC12315 showed great content than others. Treatment with KACC12315 showed the greatest content of trans-ferulic acid. As a result of relative performance indexing analysis, L. mesenteroides KCCM35046 and KACC12315 were selected as the best strain for the fermentation of Aronia.

Memory Impairment in Estrogen Receptor α Knockout Mice Through Accumulation of Amyloid-β Peptides

Hwang, Chul Ju,Yun, Hyung-Mun,Park, Kyung-Ran,Song, Ju Kyung,Seo, Hyun Ok,Hyun, Byung Kook,Choi, Dong Young,Yoo, Hwan-Soo,Oh, Ki-Wan,Hwang, Dae Yeun,Han, Sang-Bae,Hong, Jin Tae Springer US 2015 Molecular Neurobiology Vol.52 No.1

<P>Estrogen has been known to reduce the development of Alzheimer’s disease (AD). However, exact mechanisms are not clear. We investigated whether estrogen can increase amyloid-beta (Aβ) degradation and affects Aβ-induced memory impairment in an estrogen deficiency model. Estrogen receptor alpha (ERα) knockout mice and wild-type mice were intracerebroventricular (ICV) infused with Aβ (300 pmol) for 2 weeks. Cognitive function was then assessed by the Morris water maze test and passive avoidance test. In addition, Western blot analysis, immunostaining, immunofluorescence staining, ELISA, and enzyme activity assays were used to examine the degree of Aβ deposition in the brains of ERα knockout mice. In our present study, Aβ was accumulated more in the ERα knockout mice brain and greatly worsened memory impairment and glial activation as well as neurogenic inflammation. These results suggest that estrogen may protect memory impairment by stimulating the degradation of Aβ and down-regulate neurogenic inflammation as well as amyloidogenesis.</P><P><B>Electronic supplementary material</B></P><P>The online version of this article (doi:10.1007/s12035-014-8853-z) contains supplementary material, which is available to authorized users.</P>