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Dry Sliding Wear Behavior of (MWCNT + GNPs) Reinforced AZ91 Magnesium Matrix Hybrid Composites
Muhammet Emre Turan,Huseyin Zengin,Yavuz Sun 대한금속·재료학회 2020 METALS AND MATERIALS International Vol.26 No.4
This study aims to improve tribological performance of magnesium alloy with the addition of carbonaceous (C-based) reinforcements. Synergetic effects of MWCNT and GNPs on wear performance of AZ91 magnesium alloy was evaluated withthis report. AZ91-0.3 wt% MWCNT and AZ91-0.15 wt% MWCNT-0.15 wt% GNPs hybrid composites were synthesizedusing hot pressing via semi powder metallurgy. Microstructures were examined by scanning electron microscope and x-raydiffraction test devices then hardness and wear tests were performed for all samples. Results clearly show that hardnessand wear behaviors of AZ91 magnesium alloy were improved significantly with the addition of reinforcements. Uniformdistribution of carbon atoms was achieved for both of two samples. AZ91-0.15 wt% MWCNT-0.15 wt% GNPs compositeshowed best wear performance among the specimens.
Kos, F. Tugba,Sendur, Mehmet Ali Nahit,Aksoy, Sercan,Celik, Huseyin Tugrul,Sezer, Sevilay,Civelek, Burak,Yaman, Sebnem,Zengin, Nurullah Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2
Background: For early detection of renal damage during the usage of cisplatin based chemotherapy, changes in renal function should be monitored carefully. In recent years, neutrophil gelatinase-associated lipocalin, a small polypeptide molecule, has shown promise as a marker of acute renal failure. The aim of this present study was to assess possible risk prediction of cisplatin-induced nephrotoxicity using serum NGAL. Materials and Methods: A total of 34 consecutive patients with documented serum creatinine at least 24 hours before every cycle of cisplatin-based chemotherapy were included in the study. Demographic and medical data including age, performance status, tumor characteristics and comorbid diseases were collected from medical charts. Renal function was evaluated at least 48 hours before the treatment and at the end of the treatment based on the Modification of Diet in Renal Disease (MDRD) formula. Before and after cisplatin infusion serum NGAL levels were measured for the first and 3rd cycles of chemotherapy. Results: The median age of the study population was 54 (32-70) years. Fifteen patients (41.1%) were treated on an adjuvant basis, whereas 19 patients (58.9%) were treated for metastatic disease. There was no correlation of serum NGAL levels with serum creatinine (r=0.20, p=0.26) and MDRD (r=-0.12, p=0.50) and creatinine clearance-Cockcroft-Gault (r=-0.22, p=0.22) after cisplatin infusion at the end of the 3rd cycle of chemotherapy. Conclusions: In our study, serum NGAL levels were not correlated with the cisplatin induced nephrotoxicity. Further prospective studies are needed to conclude that serum NGAL level is not a good surrogate marker to predict early cisplatin induced nephrotoxicity.